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The map label for this gene is uvsE [H]

Identifier: 110634765

GI number: 110634765

Start: 2597296

End: 2598357

Strand: Direct

Name: uvsE [H]

Synonym: Meso_2424

Alternate gene names: 110634765

Gene position: 2597296-2598357 (Clockwise)

Preceding gene: 110634764

Following gene: 110634766

Centisome position: 58.86

GC content: 59.42

Gene sequence:

>1062_bases
ATGAGCGAAGGGCCGCTGCGACTTGGGTTCCCGGTCAAAGTGATGGGCGATCCCACACTCAAGAGCAATGACAGCCGCCG
CTGGGCGAACAATCCGCACCTGAAAGTCTCGCTCGAGTATCTTGATGCGATCTTCGATTATCTGGTGCGCCATAACATCA
ATATGTATCGAATGTCTTCGGACCTTGCTCCCTATGCCACACATCCCGATATGCCACAGTTCCACGGCATGATCAGGCAA
AGCGCCGGTGAACTGCAGGCGATCGGCCGCAAGGCTCGCGATCTGAACCTGCGGCTGTCGTTCCATCCCTCGCAATTCGT
GGTGCTGAACAGCCCGGACGCGGAATTGGTCCGCAAGAGCGTCTGGGATCTGTCGGCGCAGGCCGAGATGCTCGACCTCA
TGGAACTCGGGCCGGAAGCTGTGGTCGTGATCCATGTGGGAGGCACCTATGACGACAGGCGGGAGAGCGCGGCGCGTTGG
GTGAAAAACTGGGAAATACTGCCCGAGCACGTACGCCGGCGGCTGGTGCTGGAGCATGATGATCTTCGTTTCAGCGCTGC
GGACGTGCTCTGGATTCACGAGCGGACCGGGGTGCGCCTAATCTTCGACTATCAGCACTTCTGCTGCCTCAATCCGGAAG
GCCTAGATATGCGCGAAACCCTGGAGGCCATCCTGAAAACCTGGCCAGGCGGCGTTCGCCCAAAGATCCACTTCTCGACG
CCGCGGACGGAGATGCGGGAGATAATCCGGAAGAACCGCAGGACGGGAAAGCAAGAGAAGATTCATGCCGCGCCCGTGTG
GACGGCGCACGCCGACTTCTGCAATCCATTTGAGTTCTCTGGCTTCATGAGGATGGCCGCAGGGCTGAATTTCGATGTAA
TGCTCGAAAGCAAGGCAAAGGACCTGGCGCTGATCCGCCTGCGGCCCGACATGCTGCGCTATGCGCCGGACGTGGCGCCC
CGGTTCGGCCTAAAACCTGCCGAGGCGGAGCGTCTTCACGAAGAGGAAGCTGCTCTGCTGGACCAGCAGACGAATGACAT
CGATCGTTCCGTGGTTGAATGA

Upstream 100 bases:

>100_bases
GGAGCGGACATGAGCAGGCGACCGGCGGAGCGCTGCGGCCGGATGCCTGGAATGAATTCGTCGCCCGGCTCGGTTTTGGG
CCGGAAGCAAGGGTCACGTC

Downstream 100 bases:

>100_bases
GGCTGGCGGGATCGCTCCGACGGCGCTCCCGTCTGGAGCCGCGCGGTCTTGCCGCCTTGCCAACGGCATCGTCAATGTAG
TTGGCTTGCGGCCGTAAGGC

Product: UV-endonuclease UvdE

Products: NA

Alternate protein names: UV-endonuclease; UVED [H]

Number of amino acids: Translated: 353; Mature: 352

Protein sequence:

>353_residues
MSEGPLRLGFPVKVMGDPTLKSNDSRRWANNPHLKVSLEYLDAIFDYLVRHNINMYRMSSDLAPYATHPDMPQFHGMIRQ
SAGELQAIGRKARDLNLRLSFHPSQFVVLNSPDAELVRKSVWDLSAQAEMLDLMELGPEAVVVIHVGGTYDDRRESAARW
VKNWEILPEHVRRRLVLEHDDLRFSAADVLWIHERTGVRLIFDYQHFCCLNPEGLDMRETLEAILKTWPGGVRPKIHFST
PRTEMREIIRKNRRTGKQEKIHAAPVWTAHADFCNPFEFSGFMRMAAGLNFDVMLESKAKDLALIRLRPDMLRYAPDVAP
RFGLKPAEAERLHEEEAALLDQQTNDIDRSVVE

Sequences:

>Translated_353_residues
MSEGPLRLGFPVKVMGDPTLKSNDSRRWANNPHLKVSLEYLDAIFDYLVRHNINMYRMSSDLAPYATHPDMPQFHGMIRQ
SAGELQAIGRKARDLNLRLSFHPSQFVVLNSPDAELVRKSVWDLSAQAEMLDLMELGPEAVVVIHVGGTYDDRRESAARW
VKNWEILPEHVRRRLVLEHDDLRFSAADVLWIHERTGVRLIFDYQHFCCLNPEGLDMRETLEAILKTWPGGVRPKIHFST
PRTEMREIIRKNRRTGKQEKIHAAPVWTAHADFCNPFEFSGFMRMAAGLNFDVMLESKAKDLALIRLRPDMLRYAPDVAP
RFGLKPAEAERLHEEEAALLDQQTNDIDRSVVE
>Mature_352_residues
SEGPLRLGFPVKVMGDPTLKSNDSRRWANNPHLKVSLEYLDAIFDYLVRHNINMYRMSSDLAPYATHPDMPQFHGMIRQS
AGELQAIGRKARDLNLRLSFHPSQFVVLNSPDAELVRKSVWDLSAQAEMLDLMELGPEAVVVIHVGGTYDDRRESAARWV
KNWEILPEHVRRRLVLEHDDLRFSAADVLWIHERTGVRLIFDYQHFCCLNPEGLDMRETLEAILKTWPGGVRPKIHFSTP
RTEMREIIRKNRRTGKQEKIHAAPVWTAHADFCNPFEFSGFMRMAAGLNFDVMLESKAKDLALIRLRPDMLRYAPDVAPR
FGLKPAEAERLHEEEAALLDQQTNDIDRSVVE

Specific function: Component in a DNA repair pathway. Removal of UV-light damaged nucleotides. Recognizes pyrimidine dimers and cleave a phosphodiester bond immediately 5' to the lesion [H]

COG id: COG4294

COG function: function code L; UV damage repair endonuclease

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the uve1/uvsE family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004601
- InterPro:   IPR013022 [H]

Pfam domain/function: PF03851 UvdE [H]

EC number: NA

Molecular weight: Translated: 40656; Mature: 40525

Theoretical pI: Translated: 6.89; Mature: 6.89

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
4.0 %Met     (Translated Protein)
4.8 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
3.7 %Met     (Mature Protein)
4.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSEGPLRLGFPVKVMGDPTLKSNDSRRWANNPHLKVSLEYLDAIFDYLVRHNINMYRMSS
CCCCCEEECCEEEECCCCCCCCCCCCCCCCCCCEEEEHHHHHHHHHHHHHCCCCEEEECC
DLAPYATHPDMPQFHGMIRQSAGELQAIGRKARDLNLRLSFHPSQFVVLNSPDAELVRKS
CCCCCCCCCCCHHHHHHHHHHHHHHHHHCCCCCEEEEEEEECCCEEEEEECCCHHHHHHH
VWDLSAQAEMLDLMELGPEAVVVIHVGGTYDDRRESAARWVKNWEILPEHVRRRLVLEHD
HHCCHHHHHHHHHHHCCCCEEEEEEECCCCCHHHHHHHHHHHCCCCCHHHHHHHEEECCC
DLRFSAADVLWIHERTGVRLIFDYQHFCCLNPEGLDMRETLEAILKTWPGGVRPKIHFST
CCEEEEEEEEEEECCCCEEEEEECCEEEEECCCCCCHHHHHHHHHHHCCCCCCCEEEECC
PRTEMREIIRKNRRTGKQEKIHAAPVWTAHADFCNPFEFSGFMRMAAGLNFDVMLESKAK
CHHHHHHHHHHHHCCCCCCCEEECCEEECCCCCCCCCHHHHHHHHHCCCCEEEEECCCCC
DLALIRLRPDMLRYAPDVAPRFGLKPAEAERLHEEEAALLDQQTNDIDRSVVE
CEEEEEECHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHCCCCHHHHHHCC
>Mature Secondary Structure 
SEGPLRLGFPVKVMGDPTLKSNDSRRWANNPHLKVSLEYLDAIFDYLVRHNINMYRMSS
CCCCEEECCEEEECCCCCCCCCCCCCCCCCCCEEEEHHHHHHHHHHHHHCCCCEEEECC
DLAPYATHPDMPQFHGMIRQSAGELQAIGRKARDLNLRLSFHPSQFVVLNSPDAELVRKS
CCCCCCCCCCCHHHHHHHHHHHHHHHHHCCCCCEEEEEEEECCCEEEEEECCCHHHHHHH
VWDLSAQAEMLDLMELGPEAVVVIHVGGTYDDRRESAARWVKNWEILPEHVRRRLVLEHD
HHCCHHHHHHHHHHHCCCCEEEEEEECCCCCHHHHHHHHHHHCCCCCHHHHHHHEEECCC
DLRFSAADVLWIHERTGVRLIFDYQHFCCLNPEGLDMRETLEAILKTWPGGVRPKIHFST
CCEEEEEEEEEEECCCCEEEEEECCEEEEECCCCCCHHHHHHHHHHHCCCCCCCEEEECC
PRTEMREIIRKNRRTGKQEKIHAAPVWTAHADFCNPFEFSGFMRMAAGLNFDVMLESKAK
CHHHHHHHHHHHHCCCCCCCEEECCEEECCCCCCCCCHHHHHHHHHCCCCEEEEECCCCC
DLALIRLRPDMLRYAPDVAPRFGLKPAEAERLHEEEAALLDQQTNDIDRSVVE
CEEEEEECHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHCCCCHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA