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The map label for this gene is yafC [C]

Identifier: 110634752

GI number: 110634752

Start: 2570291

End: 2571205

Strand: Direct

Name: yafC [C]

Synonym: Meso_2411

Alternate gene names: 110634752

Gene position: 2570291-2571205 (Clockwise)

Preceding gene: 110634733

Following gene: 110634753

Centisome position: 58.25

GC content: 61.97

Gene sequence:

>915_bases
GTGGCGCGTAATTCAGCAAAGGCGGTAGGCGTGAACAAATTTCAGGATATTCTTGCCTTCGCGAGAGTGGCCGAACTTGG
TGGCTTCACTGCCGCAGCGAAGGTGCTGTCCTCGTCAACCTCGACCGTGACCAAGCGTGTGACGCGGCTGGAGGAAACCT
TGGGCGTGCAACTCCTCCATCGCACCACGCGCCGGATGCATTTGACCGAGTTCGGCGCGGAATATTACGAGCGCTGCAAG
CAGATCCTCTCCGACCTCGATGATGCCGATAGCGCGATCCGCGATGCTCATATTTCGGCCAGCGGCCTGGTGCGCATGGC
GCTGCCGCCCTCCTTCGGACGCATGACGGTGATCCCCGCCCTTGCGCAGTTCTATGAACGTCACCCGAATGTCAGCCTCG
ACCTGTGCTTCAAGAGCCAGACCGCCAATCCGATCGAAGGCGGCTTCGACCTGGTTGTGCATTCGGGCCGGCTGGCGGAT
TCGCTGCTGGTCAACCGCATCCTTGTCCGCGGGGCACAGAAGACCGTCGCCTCGCCCGATTATCTTGCCCGCCACGGCCG
GCCGATGGTTCCCTCCGATCTCGTCCATCATAACTGCATCGTCGGCGCCTTCGGCCCTGCCTGGCATTTCCGCGATGAAG
CCGGGCATGAAGAGATCGTGCGCGTATCGGGAAAGTTCGTCACCGACAGCGGCGATATCCTGCGCGAGGCCGCCGTGCAG
GGCCTCGGCATTTCCCAGGCCACCTGGTGGCTGTTTCGTGAGGACATGCAGCGCGGGCGGCTGGTTCCCGTACTTGAGGA
ATACGAGGTCGAGGCTGACCCGATCTCCATCGTGTTTCCGGCCAATCGCCGCGTTCCTGCTAAAGTGCGGGTCTTCGTCG
ACTTCCTGCTGACCATCACGCGGAGCAATCCCTAG

Upstream 100 bases:

>100_bases
CGGCTTTAGCTCCTCGGGCAGTCCAAAAAATCGGCATGATACTTGCTTTGCACCACCGCAGGGCCACGGAGAAGGCTTGG
ATGACTCATGAGGCGCCATC

Downstream 100 bases:

>100_bases
GCCGCACCTGACCTGCCCGTCCGCATGGGCCGTTCACGCACTAACACCGCGACAATATCCCCCACGTTGACGTGGATCCG
GGTTATGCTGGTTCGAAGCG

Product: LysR family transcriptional regulator

Products: NA

Alternate protein names: ORF2 [H]

Number of amino acids: Translated: 304; Mature: 303

Protein sequence:

>304_residues
MARNSAKAVGVNKFQDILAFARVAELGGFTAAAKVLSSSTSTVTKRVTRLEETLGVQLLHRTTRRMHLTEFGAEYYERCK
QILSDLDDADSAIRDAHISASGLVRMALPPSFGRMTVIPALAQFYERHPNVSLDLCFKSQTANPIEGGFDLVVHSGRLAD
SLLVNRILVRGAQKTVASPDYLARHGRPMVPSDLVHHNCIVGAFGPAWHFRDEAGHEEIVRVSGKFVTDSGDILREAAVQ
GLGISQATWWLFREDMQRGRLVPVLEEYEVEADPISIVFPANRRVPAKVRVFVDFLLTITRSNP

Sequences:

>Translated_304_residues
MARNSAKAVGVNKFQDILAFARVAELGGFTAAAKVLSSSTSTVTKRVTRLEETLGVQLLHRTTRRMHLTEFGAEYYERCK
QILSDLDDADSAIRDAHISASGLVRMALPPSFGRMTVIPALAQFYERHPNVSLDLCFKSQTANPIEGGFDLVVHSGRLAD
SLLVNRILVRGAQKTVASPDYLARHGRPMVPSDLVHHNCIVGAFGPAWHFRDEAGHEEIVRVSGKFVTDSGDILREAAVQ
GLGISQATWWLFREDMQRGRLVPVLEEYEVEADPISIVFPANRRVPAKVRVFVDFLLTITRSNP
>Mature_303_residues
ARNSAKAVGVNKFQDILAFARVAELGGFTAAAKVLSSSTSTVTKRVTRLEETLGVQLLHRTTRRMHLTEFGAEYYERCKQ
ILSDLDDADSAIRDAHISASGLVRMALPPSFGRMTVIPALAQFYERHPNVSLDLCFKSQTANPIEGGFDLVVHSGRLADS
LLVNRILVRGAQKTVASPDYLARHGRPMVPSDLVHHNCIVGAFGPAWHFRDEAGHEEIVRVSGKFVTDSGDILREAAVQG
LGISQATWWLFREDMQRGRLVPVLEEYEVEADPISIVFPANRRVPAKVRVFVDFLLTITRSNP

Specific function: Unknown

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH lysR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1786401, Length=295, Percent_Identity=32.2033898305085, Blast_Score=158, Evalue=5e-40,
Organism=Escherichia coli, GI145693193, Length=296, Percent_Identity=31.0810810810811, Blast_Score=157, Evalue=8e-40,
Organism=Escherichia coli, GI87081978, Length=288, Percent_Identity=33.3333333333333, Blast_Score=140, Evalue=1e-34,
Organism=Escherichia coli, GI1789639, Length=288, Percent_Identity=28.125, Blast_Score=128, Evalue=5e-31,
Organism=Escherichia coli, GI1787128, Length=284, Percent_Identity=26.4084507042254, Blast_Score=124, Evalue=5e-30,
Organism=Escherichia coli, GI1789440, Length=285, Percent_Identity=27.3684210526316, Blast_Score=118, Evalue=4e-28,
Organism=Escherichia coli, GI1787589, Length=290, Percent_Identity=27.5862068965517, Blast_Score=114, Evalue=9e-27,
Organism=Escherichia coli, GI1788706, Length=287, Percent_Identity=25.4355400696864, Blast_Score=86, Evalue=3e-18,
Organism=Escherichia coli, GI1789173, Length=271, Percent_Identity=25.0922509225092, Blast_Score=78, Evalue=8e-16,
Organism=Escherichia coli, GI157672245, Length=121, Percent_Identity=35.5371900826446, Blast_Score=75, Evalue=7e-15,
Organism=Escherichia coli, GI145693105, Length=140, Percent_Identity=29.2857142857143, Blast_Score=72, Evalue=3e-14,
Organism=Escherichia coli, GI1787601, Length=121, Percent_Identity=28.9256198347107, Blast_Score=65, Evalue=5e-12,
Organism=Escherichia coli, GI1786448, Length=282, Percent_Identity=25.531914893617, Blast_Score=65, Evalue=6e-12,

Paralogues:

None

Copy number: 10-20 Molecules/Cell [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000847
- InterPro:   IPR005119
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00126 HTH_1; PF03466 LysR_substrate [H]

EC number: NA

Molecular weight: Translated: 33647; Mature: 33516

Theoretical pI: Translated: 8.50; Mature: 8.50

Prosite motif: PS50931 HTH_LYSR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
2.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MARNSAKAVGVNKFQDILAFARVAELGGFTAAAKVLSSSTSTVTKRVTRLEETLGVQLLH
CCCCCCCCCCHHHHHHHHHHHHHHHHCCHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHH
RTTRRMHLTEFGAEYYERCKQILSDLDDADSAIRDAHISASGLVRMALPPSFGRMTVIPA
HHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHCCCCCCEEEEECCCCCCCHHHHHH
LAQFYERHPNVSLDLCFKSQTANPIEGGFDLVVHSGRLADSLLVNRILVRGAQKTVASPD
HHHHHHHCCCCEEEEEEECCCCCCCCCCEEEEEECCCHHHHHHHHHHHHHCHHHHCCCCH
YLARHGRPMVPSDLVHHNCIVGAFGPAWHFRDEAGHEEIVRVSGKFVTDSGDILREAAVQ
HHHHCCCCCCCHHHHHCCEEEECCCCCCCCCCCCCHHHHHHCCCCEEECCHHHHHHHHHH
GLGISQATWWLFREDMQRGRLVPVLEEYEVEADPISIVFPANRRVPAKVRVFVDFLLTIT
CCCCCHHHHHHHHHHHHCCCCCCCHHHCCCCCCCEEEEECCCCCCCHHHHHHHHHHHHHH
RSNP
CCCC
>Mature Secondary Structure 
ARNSAKAVGVNKFQDILAFARVAELGGFTAAAKVLSSSTSTVTKRVTRLEETLGVQLLH
CCCCCCCCCHHHHHHHHHHHHHHHHCCHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHH
RTTRRMHLTEFGAEYYERCKQILSDLDDADSAIRDAHISASGLVRMALPPSFGRMTVIPA
HHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHCCCCCCEEEEECCCCCCCHHHHHH
LAQFYERHPNVSLDLCFKSQTANPIEGGFDLVVHSGRLADSLLVNRILVRGAQKTVASPD
HHHHHHHCCCCEEEEEEECCCCCCCCCCEEEEEECCCHHHHHHHHHHHHHCHHHHCCCCH
YLARHGRPMVPSDLVHHNCIVGAFGPAWHFRDEAGHEEIVRVSGKFVTDSGDILREAAVQ
HHHHCCCCCCCHHHHHCCEEEECCCCCCCCCCCCCHHHHHHCCCCEEECCHHHHHHHHHH
GLGISQATWWLFREDMQRGRLVPVLEEYEVEADPISIVFPANRRVPAKVRVFVDFLLTIT
CCCCCHHHHHHHHHHHHCCCCCCCHHHCCCCCCCEEEEECCCCCCCHHHHHHHHHHHHHH
RSNP
CCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8635745; 7542800 [H]