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The map label for this gene is fnrL [H]

Identifier: 110634625

GI number: 110634625

Start: 2429355

End: 2430131

Strand: Direct

Name: fnrL [H]

Synonym: Meso_2279

Alternate gene names: 110634625

Gene position: 2429355-2430131 (Clockwise)

Preceding gene: 110634624

Following gene: 110634626

Centisome position: 55.06

GC content: 57.79

Gene sequence:

>777_bases
ATGACCGCGTTGTCCACCCTGCACACGCCCGCAGCCGATCAATCGACCACCCAGCGCTGTTCCATATGTCAAGGAATGGA
ACCGGAATTGCACCGGCAACTCCAGCGCCTCGGCCGGATCAAAAGATATGCTGCAGGCGAAATTATCGTCGGTGAGGAAG
AGGAAGCTCCCTTCGTCGGCACCGTCACGAGTGGCGTGCTAAGAATGCAGAAGACGCTGTACGACGGACGACAGTTGATC
GTTGGGCTCCTGATGCCTTCCGACATGTTCGGCCGCGTCTTCTCCTCCACCTCGAATGTTTCGATCGAAGCGGCAACGGA
CGTGACGCTATGCTGCTACAGTCGTGCCGGCTTCGAAATCTTGCTTTCGCAATTCCCTGCATTGGAGCACCGGATGCTGC
TCTCGATGCTCGATGAGCTTCAGAGCGCGCAGAACTGGATGCTGCTACTGGGCTGCCAGTCAGTGACTGAACGCATTGCC
ACCTTTCTCCTGGTCCTTCGCCGCCGCTCGGCCAAATTTCCACCGGATTCCCTTCAGTGTCTGGGCAACTCGGTGACGAT
CCCGATCTCGCGCCGAGACATGGCCGCCTATCTGGGGACGACGGTCGAATCGATCAGCCGCTCCATTCAGGAAATGGCGC
GGCATCGTGTTTTGAGCATCATCAACCCCCAGCGATTCCGTATCCTGGACGAACGTCGCCTAATCGAACTTTCTGGGCGC
GACGTTACCGAAATGAAGCTCAGCGTTCCGGTGGAACGAATATTGCGCACCGCCTGA

Upstream 100 bases:

>100_bases
CTCTGCCAATCTGGCATTTGAGAAGGAAACAGGAGCAGCCCGACCGCTGCTTGCCTCAACCAGCGGCGCGAAATCGCATC
CTTGCCTGTCGAGGGAACCA

Downstream 100 bases:

>100_bases
TCGGCGCGAGACTTGATACGGCTCAATGCAACTGGCCGCCTACCGTGGGAAGAGGTGCTTTTCAGGAGTACTGCCATGAC
ACATACCACCATATCCAGCT

Product: Crp/FNR family transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 258; Mature: 257

Protein sequence:

>258_residues
MTALSTLHTPAADQSTTQRCSICQGMEPELHRQLQRLGRIKRYAAGEIIVGEEEEAPFVGTVTSGVLRMQKTLYDGRQLI
VGLLMPSDMFGRVFSSTSNVSIEAATDVTLCCYSRAGFEILLSQFPALEHRMLLSMLDELQSAQNWMLLLGCQSVTERIA
TFLLVLRRRSAKFPPDSLQCLGNSVTIPISRRDMAAYLGTTVESISRSIQEMARHRVLSIINPQRFRILDERRLIELSGR
DVTEMKLSVPVERILRTA

Sequences:

>Translated_258_residues
MTALSTLHTPAADQSTTQRCSICQGMEPELHRQLQRLGRIKRYAAGEIIVGEEEEAPFVGTVTSGVLRMQKTLYDGRQLI
VGLLMPSDMFGRVFSSTSNVSIEAATDVTLCCYSRAGFEILLSQFPALEHRMLLSMLDELQSAQNWMLLLGCQSVTERIA
TFLLVLRRRSAKFPPDSLQCLGNSVTIPISRRDMAAYLGTTVESISRSIQEMARHRVLSIINPQRFRILDERRLIELSGR
DVTEMKLSVPVERILRTA
>Mature_257_residues
TALSTLHTPAADQSTTQRCSICQGMEPELHRQLQRLGRIKRYAAGEIIVGEEEEAPFVGTVTSGVLRMQKTLYDGRQLIV
GLLMPSDMFGRVFSSTSNVSIEAATDVTLCCYSRAGFEILLSQFPALEHRMLLSMLDELQSAQNWMLLLGCQSVTERIAT
FLLVLRRRSAKFPPDSLQCLGNSVTIPISRRDMAAYLGTTVESISRSIQEMARHRVLSIINPQRFRILDERRLIELSGRD
VTEMKLSVPVERILRTA

Specific function: Anaerobic regulatory protein; transcriptional activator of hemA. Appears to regulate other genes [H]

COG id: COG0664

COG function: function code T; cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH crp-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1787595, Length=214, Percent_Identity=26.1682242990654, Blast_Score=62, Evalue=4e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR018490
- InterPro:   IPR000595
- InterPro:   IPR001808
- InterPro:   IPR012318
- InterPro:   IPR014710
- InterPro:   IPR018335
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00027 cNMP_binding; PF00325 Crp [H]

EC number: NA

Molecular weight: Translated: 28961; Mature: 28830

Theoretical pI: Translated: 8.38; Mature: 8.38

Prosite motif: PS50042 CNMP_BINDING_3 ; PS00042 HTH_CRP_1 ; PS51063 HTH_CRP_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.3 %Cys     (Translated Protein)
4.3 %Met     (Translated Protein)
6.6 %Cys+Met (Translated Protein)
2.3 %Cys     (Mature Protein)
3.9 %Met     (Mature Protein)
6.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTALSTLHTPAADQSTTQRCSICQGMEPELHRQLQRLGRIKRYAAGEIIVGEEEEAPFVG
CCCCCCCCCCCCCCHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHCCCEEECCCCCCCEEH
TVTSGVLRMQKTLYDGRQLIVGLLMPSDMFGRVFSSTSNVSIEAATDVTLCCYSRAGFEI
HHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHCCCCCEEEEECCCEEEEHCCCCCHHH
LLSQFPALEHRMLLSMLDELQSAQNWMLLLGCQSVTERIATFLLVLRRRSAKFPPDSLQC
HHHHCCHHHHHHHHHHHHHHHHHCCEEEEEEHHHHHHHHHHHHHHHHHHCCCCCCHHHHH
LGNSVTIPISRRDMAAYLGTTVESISRSIQEMARHRVLSIINPQRFRILDERRLIELSGR
CCCCEEEEECHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHEEHHHHHEEEECCC
DVTEMKLSVPVERILRTA
CHHHHHHHCCHHHHHHCC
>Mature Secondary Structure 
TALSTLHTPAADQSTTQRCSICQGMEPELHRQLQRLGRIKRYAAGEIIVGEEEEAPFVG
CCCCCCCCCCCCCHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHCCCEEECCCCCCCEEH
TVTSGVLRMQKTLYDGRQLIVGLLMPSDMFGRVFSSTSNVSIEAATDVTLCCYSRAGFEI
HHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHCCCCCEEEEECCCEEEEHCCCCCHHH
LLSQFPALEHRMLLSMLDELQSAQNWMLLLGCQSVTERIATFLLVLRRRSAKFPPDSLQC
HHHHCCHHHHHHHHHHHHHHHHHCCEEEEEEHHHHHHHHHHHHHHHHHHCCCCCCHHHHH
LGNSVTIPISRRDMAAYLGTTVESISRSIQEMARHRVLSIINPQRFRILDERRLIELSGR
CCCCEEEEECHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHEEHHHHHEEEECCC
DVTEMKLSVPVERILRTA
CHHHHHHHCCHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: Fe [C]

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7592416 [H]