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The map label for this gene is fixN [H]

Identifier: 110634597

GI number: 110634597

Start: 2404323

End: 2405966

Strand: Direct

Name: fixN [H]

Synonym: Meso_2250

Alternate gene names: 110634597

Gene position: 2404323-2405966 (Clockwise)

Preceding gene: 110634596

Following gene: 110634598

Centisome position: 54.49

GC content: 64.11

Gene sequence:

>1644_bases
TTGATCGCGCAGCTTACCATTGCCGAGAGACAAGTCGGCTTGGCCCTTGCCGGGCTCGTCACCCTCATGGGCGCCGCGCT
CGGCATTGCCGGACGCAACGACGTGCTGGGCTATCAGGGTCTGCTGATCGTAGTCTTCGGCGCGCTCGTCATGATCACGC
TTCTGCGCAACCTCGACGCACCCGAGCCGGACGAGAGCCGGCTTGCCGAATATTACGACGACCCGATCCGCGTCGGCATC
GTGCTGACGATGCTGTGGGCCATCTTTGGCATGTTCATCGGCGTGTGGGTGGCCGCACTTCTGGCCTGGCCAGAGCTGAC
CTTTGATGCGGCCTGGGCGAGCTTCGGGCGCCTGCGCCCGGCGCACACGACAGGCGTCATCTTCGGCTTCGGCGGCAACG
CGCTGATCGCCACTTCGCTGCATGTCGTGCAGCGCACCTCGCGCGCCCGCCTGCCCGACCAGGTCAGCCCCTGGTTCGTG
CTGCTCGGCTACAACCTCTTCTGCCTGCTCGCCGTCTCCGGCTATTTCCTCGGCATCACGCAGTCGAAGGAATATGCCGA
GCCGGAATGGTATGCCGATATCTGGCTGGTCGTCGTATGGGTCGCCTATTTCGCGCTCTATATCCGCACGCTCGCCCGCC
GCAAGGAGCCGCACATCTATGTGGCGAACTGGTACTTCATGGCCTTCATCCTGGTCGTGGCGGTCCTGCACATCGTCAAC
AACCTCGCCGTGCCCGTCTCCTTCGGCAGCGCCAAGGCCTATTCCGCCTTTTCCGGCGTGCAAGACGCGATGACGCAGTG
GTGGTACGGCCACAACGCCGTCGCCTTCTTCCTCACCGCCGGCTTCCTGGGCATGATGTACTACTACCTGCCGAAGCGTG
CCGAGCGGCCGATCTATTCCTACCGGCTGTCGATCATCAGCTTCTGGGGCATCACCTTCATGTATATGTGGGCGGGCTCG
CACCACCTGCACTACACCGCCCTGCCCCACTGGGTGCAGACGCTGGGCATGACCTTCTCGGTGGTGCTGCTCGTGCCTTC
CTGGGCCTCGGCCGCCAACGCGCTTCTCACCCTCAACGGCGCCTGGCACAAGGTGCGCGACGATGCCACGCTGCGCTTCA
TGATGGTGGCCGCCGTCTTCTACGGCCTGTCCACCTTCGAAGGCTCGTTCCTCGCAATCCGCGCAGTGAACTCGCTCTCG
CACTACACCGACTGGACCGTCGGGCACGTCCATGCCGGCGCGCTCGGCTGGGTGGCGATGATCACCTTCGGCGCGCTGTA
TACGCTGACGCCGGCCATGTGGAAGCGCCCGCGCATGTACTCCAACACGCTGGTGGAGGTGCACTTCTGGTGCGCGGTGA
TCGGCACGCTGATCTACGTCTTCGCCATGTGGAATTCCGGCATCATCCAGGGGCTGATGTGGCGCACCTACAATGAGAGC
GGGACGCTGACCTACTCCTTCATCGAATCGCTGATCGCCATGCACCCCTATTACATCGCGCGCACCGTCGGCGGGCTCTT
CTTCCTGATCGGCGCGGTGGTCGGCACCTACAACATCTTCATGACGATCCGGCACGAGCCGCTGCCGCTCAGCCAGCAGG
CGGAACCACTCGGCGCCGACCGTCCGCTCGTGCCGGGGGAGTAA

Upstream 100 bases:

>100_bases
TTCTCTGCCGGATTTGATCCAGAGCAAAGTCGGGCCCGGCCCGATGCCTCAAAGCGGTCACGATGAAGCAAATGCAGCAA
CGTCACCGATGGGGAAACAA

Downstream 100 bases:

>100_bases
GGATATGCCTGAAGCACACAGGAAACTCGAACGCACGGCCGTCGGCTTCGTGCTGGCCATCATCGGTGTCTCCAGCATCG
GCGGGCTGGTCGAGATCGCG

Product: cbb3-type cytochrome c oxidase subunit I

Products: NA

Alternate protein names: Cytochrome CBB3 subunit 1; Cytochrome c oxidase polypeptide I homolog; Heme B/copper cytochrome c oxidase subunit [H]

Number of amino acids: Translated: 547; Mature: 547

Protein sequence:

>547_residues
MIAQLTIAERQVGLALAGLVTLMGAALGIAGRNDVLGYQGLLIVVFGALVMITLLRNLDAPEPDESRLAEYYDDPIRVGI
VLTMLWAIFGMFIGVWVAALLAWPELTFDAAWASFGRLRPAHTTGVIFGFGGNALIATSLHVVQRTSRARLPDQVSPWFV
LLGYNLFCLLAVSGYFLGITQSKEYAEPEWYADIWLVVVWVAYFALYIRTLARRKEPHIYVANWYFMAFILVVAVLHIVN
NLAVPVSFGSAKAYSAFSGVQDAMTQWWYGHNAVAFFLTAGFLGMMYYYLPKRAERPIYSYRLSIISFWGITFMYMWAGS
HHLHYTALPHWVQTLGMTFSVVLLVPSWASAANALLTLNGAWHKVRDDATLRFMMVAAVFYGLSTFEGSFLAIRAVNSLS
HYTDWTVGHVHAGALGWVAMITFGALYTLTPAMWKRPRMYSNTLVEVHFWCAVIGTLIYVFAMWNSGIIQGLMWRTYNES
GTLTYSFIESLIAMHPYYIARTVGGLFFLIGAVVGTYNIFMTIRHEPLPLSQQAEPLGADRPLVPGE

Sequences:

>Translated_547_residues
MIAQLTIAERQVGLALAGLVTLMGAALGIAGRNDVLGYQGLLIVVFGALVMITLLRNLDAPEPDESRLAEYYDDPIRVGI
VLTMLWAIFGMFIGVWVAALLAWPELTFDAAWASFGRLRPAHTTGVIFGFGGNALIATSLHVVQRTSRARLPDQVSPWFV
LLGYNLFCLLAVSGYFLGITQSKEYAEPEWYADIWLVVVWVAYFALYIRTLARRKEPHIYVANWYFMAFILVVAVLHIVN
NLAVPVSFGSAKAYSAFSGVQDAMTQWWYGHNAVAFFLTAGFLGMMYYYLPKRAERPIYSYRLSIISFWGITFMYMWAGS
HHLHYTALPHWVQTLGMTFSVVLLVPSWASAANALLTLNGAWHKVRDDATLRFMMVAAVFYGLSTFEGSFLAIRAVNSLS
HYTDWTVGHVHAGALGWVAMITFGALYTLTPAMWKRPRMYSNTLVEVHFWCAVIGTLIYVFAMWNSGIIQGLMWRTYNES
GTLTYSFIESLIAMHPYYIARTVGGLFFLIGAVVGTYNIFMTIRHEPLPLSQQAEPLGADRPLVPGE
>Mature_547_residues
MIAQLTIAERQVGLALAGLVTLMGAALGIAGRNDVLGYQGLLIVVFGALVMITLLRNLDAPEPDESRLAEYYDDPIRVGI
VLTMLWAIFGMFIGVWVAALLAWPELTFDAAWASFGRLRPAHTTGVIFGFGGNALIATSLHVVQRTSRARLPDQVSPWFV
LLGYNLFCLLAVSGYFLGITQSKEYAEPEWYADIWLVVVWVAYFALYIRTLARRKEPHIYVANWYFMAFILVVAVLHIVN
NLAVPVSFGSAKAYSAFSGVQDAMTQWWYGHNAVAFFLTAGFLGMMYYYLPKRAERPIYSYRLSIISFWGITFMYMWAGS
HHLHYTALPHWVQTLGMTFSVVLLVPSWASAANALLTLNGAWHKVRDDATLRFMMVAAVFYGLSTFEGSFLAIRAVNSLS
HYTDWTVGHVHAGALGWVAMITFGALYTLTPAMWKRPRMYSNTLVEVHFWCAVIGTLIYVFAMWNSGIIQGLMWRTYNES
GTLTYSFIESLIAMHPYYIARTVGGLFFLIGAVVGTYNIFMTIRHEPLPLSQQAEPLGADRPLVPGE

Specific function: Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. Co I is the catalytic subunit of the enzyme. Electrons originating in cytochrome

COG id: COG3278

COG function: function code O; Cbb3-type cytochrome oxidase, subunit 1

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the heme-copper respiratory oxidase family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004677
- InterPro:   IPR000883 [H]

Pfam domain/function: PF00115 COX1 [H]

EC number: =1.9.3.1 [H]

Molecular weight: Translated: 61237; Mature: 61237

Theoretical pI: Translated: 8.19; Mature: 8.19

Prosite motif: PS50855 COX1 ; PS00077 COX1_CUB

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
3.8 %Met     (Translated Protein)
4.2 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
3.8 %Met     (Mature Protein)
4.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIAQLTIAERQVGLALAGLVTLMGAALGIAGRNDVLGYQGLLIVVFGALVMITLLRNLDA
CCCEEEHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCC
PEPDESRLAEYYDDPIRVGIVLTMLWAIFGMFIGVWVAALLAWPELTFDAAWASFGRLRP
CCCCHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHCCCCC
AHTTGVIFGFGGNALIATSLHVVQRTSRARLPDQVSPWFVLLGYNLFCLLAVSGYFLGIT
CCCCEEEEECCCCCHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHEEEE
QSKEYAEPEWYADIWLVVVWVAYFALYIRTLARRKEPHIYVANWYFMAFILVVAVLHIVN
CCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEHHHHHHHHHHHHHHHHHC
NLAVPVSFGSAKAYSAFSGVQDAMTQWWYGHNAVAFFLTAGFLGMMYYYLPKRAERPIYS
CCCEEEECCCCHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHCHHCCCCHHH
YRLSIISFWGITFMYMWAGSHHLHYTALPHWVQTLGMTFSVVLLVPSWASAANALLTLNG
HHHHHHHHHHHHHHHHHCCCCCEEEHHHHHHHHHHHHHHEEEEEECCHHHHCCEEEEECC
AWHKVRDDATLRFMMVAAVFYGLSTFEGSFLAIRAVNSLSHYTDWTVGHVHAGALGWVAM
CHHHHCCCHHHHHHHHHHHHHHHHHCCCCEEEEEEHHHHHHHCCCCCHHHHHHHHHHHHH
ITFGALYTLTPAMWKRPRMYSNTLVEVHFWCAVIGTLIYVFAMWNSGIIQGLMWRTYNES
HHHHHHHHHCHHHHCCCCHHHCHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHEECCC
GTLTYSFIESLIAMHPYYIARTVGGLFFLIGAVVGTYNIFMTIRHEPLPLSQQAEPLGAD
CCCHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHEEEEEEEECCCCCCCCCCCCCCCC
RPLVPGE
CCCCCCC
>Mature Secondary Structure
MIAQLTIAERQVGLALAGLVTLMGAALGIAGRNDVLGYQGLLIVVFGALVMITLLRNLDA
CCCEEEHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCC
PEPDESRLAEYYDDPIRVGIVLTMLWAIFGMFIGVWVAALLAWPELTFDAAWASFGRLRP
CCCCHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHCCCCC
AHTTGVIFGFGGNALIATSLHVVQRTSRARLPDQVSPWFVLLGYNLFCLLAVSGYFLGIT
CCCCEEEEECCCCCHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHEEEE
QSKEYAEPEWYADIWLVVVWVAYFALYIRTLARRKEPHIYVANWYFMAFILVVAVLHIVN
CCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEHHHHHHHHHHHHHHHHHC
NLAVPVSFGSAKAYSAFSGVQDAMTQWWYGHNAVAFFLTAGFLGMMYYYLPKRAERPIYS
CCCEEEECCCCHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHCHHCCCCHHH
YRLSIISFWGITFMYMWAGSHHLHYTALPHWVQTLGMTFSVVLLVPSWASAANALLTLNG
HHHHHHHHHHHHHHHHHCCCCCEEEHHHHHHHHHHHHHHEEEEEECCHHHHCCEEEEECC
AWHKVRDDATLRFMMVAAVFYGLSTFEGSFLAIRAVNSLSHYTDWTVGHVHAGALGWVAM
CHHHHCCCHHHHHHHHHHHHHHHHHCCCCEEEEEEHHHHHHHCCCCCHHHHHHHHHHHHH
ITFGALYTLTPAMWKRPRMYSNTLVEVHFWCAVIGTLIYVFAMWNSGIIQGLMWRTYNES
HHHHHHHHHCHHHHCCCCHHHCHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHEECCC
GTLTYSFIESLIAMHPYYIARTVGGLFFLIGAVVGTYNIFMTIRHEPLPLSQQAEPLGAD
CCCHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHEEEEEEEECCCCCCCCCCCCCCCC
RPLVPGE
CCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 8386371; 12597275 [H]