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The map label for this gene is ackA [H]

Identifier: 110634583

GI number: 110634583

Start: 2387173

End: 2388345

Strand: Reverse

Name: ackA [H]

Synonym: Meso_2235

Alternate gene names: 110634583

Gene position: 2388345-2387173 (Counterclockwise)

Preceding gene: 110634584

Following gene: 110634582

Centisome position: 54.13

GC content: 64.54

Gene sequence:

>1173_bases
ATGCCGAATACCATCCTCGCTCTCAATGCCGGCTCCTCGAGCCTCAAGTTCGGTCTCTACGAGGCTGGCTCTTCAGGAGA
ACCGCGCTCCATGGCCCGTGGCGCAGTCGGCCTTCGCGACGTGCGCAGCCTGACCGCCAAGGGCCCGGATGGGAAAACGC
TTCTGGAGAAGGAGTTGCCAGGCAGGGGCCTTGAAGATGCGATCGGCGAATTGCTCCGTTGGGCCGACAGTTGGACCGGT
CAGGGGCTTGTTGCAGCCGGTCACCGCATCGTCCACGGCGGCGGCCGGTTCTCAGACCCGGTGCTGCTGACGCCACCGGT
GATCGATGCAGTGGAGGAACTGACGCCGCTTGCGCCGCTCCATCAGCCGCGCAGCATCGCCCCTATCCGTGCTCTTACTG
CCTTGCGACCGCATTTGCCGCAGGTCGGCTGCTTCGACACGGCTTTTCACGGGACGATTGAGGCCACGGTCAGGCGCTAT
GCCCTGCCTCGGCACTATGAGGCTATGGGGATCCAGCGATACGGATTCCACGGCCTTTCCTACGAACACATAGCATCCCG
CCTGCGGCAGGTGTCTCCGGAACTCGCGGCAGGCCGGATCGTCGTCGCGCATCTTGGAAACGGCGCGAGCCTATGCGCCC
TGCACGACGGCAACAGCGTCGACACCACCATGGGCTTTTCCGCGCTCGACGGCCTGGTGATGGGCACGCGCTGCGGTGCG
ATCGATCCGGGCGTGCTCCTTTACCTCCTTCAGGAGGAGGGGTTTTCTCCCGCGGAGCTTCAGCATGTGCTTTACGAGGG
GTCCGGCCTTCTGGGGGTTTCCGGTATCTCGAGCGACGTGCGAGAGCTTTCGGCCAGCGACGATCCGCGCGCCCGCGAAG
CGCTCGAACTCTTCGCCTTCCGCGCGGCGCGAGAGACGGCGGCACTGGCCAGTACGATGGGCGGCCTCGACGGCTTGGTA
TTCACTGCAGGAATAGGCGAGCACTCGGCCTCGATCCGCTCGGCCATCTGCTCACGTCTGACATGGCTCGGCGCAAGGAT
CGATCACGACGCCAACGATTCCCATGCGGAGCGGATCAGCGCTGTGGACAGCCCGGTCGACGTATACGTGATCCCGACCG
ACGAGGAAGTGGTGATCGCACGCCATGTCCTGTCAGCGGTCGGGAAGGTTTAG

Upstream 100 bases:

>100_bases
TCGTTGAGCACGCCGCCTATATCCGCCAGCACGGCGAGGACATGCCCGAGATCCGCGATTGGGGGTGGCCCTACAAGACG
GCCGCCGAAGCCGGTGACTG

Downstream 100 bases:

>100_bases
TCTCGCGGCGGCGCATGCCGGCGACGACCGGTCCCATGAAGGAACAGAAGGCCATGGACACTCTCCAACAGTTTCTGAGG
CACACCAGCATTGCCTACTT

Product: acetate kinase

Products: NA

Alternate protein names: Acetokinase [H]

Number of amino acids: Translated: 390; Mature: 389

Protein sequence:

>390_residues
MPNTILALNAGSSSLKFGLYEAGSSGEPRSMARGAVGLRDVRSLTAKGPDGKTLLEKELPGRGLEDAIGELLRWADSWTG
QGLVAAGHRIVHGGGRFSDPVLLTPPVIDAVEELTPLAPLHQPRSIAPIRALTALRPHLPQVGCFDTAFHGTIEATVRRY
ALPRHYEAMGIQRYGFHGLSYEHIASRLRQVSPELAAGRIVVAHLGNGASLCALHDGNSVDTTMGFSALDGLVMGTRCGA
IDPGVLLYLLQEEGFSPAELQHVLYEGSGLLGVSGISSDVRELSASDDPRAREALELFAFRAARETAALASTMGGLDGLV
FTAGIGEHSASIRSAICSRLTWLGARIDHDANDSHAERISAVDSPVDVYVIPTDEEVVIARHVLSAVGKV

Sequences:

>Translated_390_residues
MPNTILALNAGSSSLKFGLYEAGSSGEPRSMARGAVGLRDVRSLTAKGPDGKTLLEKELPGRGLEDAIGELLRWADSWTG
QGLVAAGHRIVHGGGRFSDPVLLTPPVIDAVEELTPLAPLHQPRSIAPIRALTALRPHLPQVGCFDTAFHGTIEATVRRY
ALPRHYEAMGIQRYGFHGLSYEHIASRLRQVSPELAAGRIVVAHLGNGASLCALHDGNSVDTTMGFSALDGLVMGTRCGA
IDPGVLLYLLQEEGFSPAELQHVLYEGSGLLGVSGISSDVRELSASDDPRAREALELFAFRAARETAALASTMGGLDGLV
FTAGIGEHSASIRSAICSRLTWLGARIDHDANDSHAERISAVDSPVDVYVIPTDEEVVIARHVLSAVGKV
>Mature_389_residues
PNTILALNAGSSSLKFGLYEAGSSGEPRSMARGAVGLRDVRSLTAKGPDGKTLLEKELPGRGLEDAIGELLRWADSWTGQ
GLVAAGHRIVHGGGRFSDPVLLTPPVIDAVEELTPLAPLHQPRSIAPIRALTALRPHLPQVGCFDTAFHGTIEATVRRYA
LPRHYEAMGIQRYGFHGLSYEHIASRLRQVSPELAAGRIVVAHLGNGASLCALHDGNSVDTTMGFSALDGLVMGTRCGAI
DPGVLLYLLQEEGFSPAELQHVLYEGSGLLGVSGISSDVRELSASDDPRAREALELFAFRAARETAALASTMGGLDGLVF
TAGIGEHSASIRSAICSRLTWLGARIDHDANDSHAERISAVDSPVDVYVIPTDEEVVIARHVLSAVGKV

Specific function: Anaerobic degradation of L-threonine to propionate. [C]

COG id: COG0282

COG function: function code C; Acetate kinase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the acetokinase family [H]

Homologues:

Organism=Escherichia coli, GI145693184, Length=399, Percent_Identity=37.844611528822, Blast_Score=233, Evalue=1e-62,
Organism=Escherichia coli, GI1788633, Length=403, Percent_Identity=35.4838709677419, Blast_Score=200, Evalue=2e-52,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000890
- InterPro:   IPR004372 [H]

Pfam domain/function: PF00871 Acetate_kinase [H]

EC number: =2.7.2.1 [H]

Molecular weight: Translated: 41280; Mature: 41149

Theoretical pI: Translated: 6.11; Mature: 6.11

Prosite motif: PS01075 ACETATE_KINASE_1 ; PS01076 ACETATE_KINASE_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
2.6 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
1.3 %Met     (Mature Protein)
2.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPNTILALNAGSSSLKFGLYEAGSSGEPRSMARGAVGLRDVRSLTAKGPDGKTLLEKELP
CCCCEEEEECCCCCEEEEEEECCCCCCCHHHHHHCCCHHHHHHHHCCCCCCCHHHHHCCC
GRGLEDAIGELLRWADSWTGQGLVAAGHRIVHGGGRFSDPVLLTPPVIDAVEELTPLAPL
CCCHHHHHHHHHHHHHCCCCCCEEECCCEEEECCCCCCCCEEECCHHHHHHHHHCCCCCC
HQPRSIAPIRALTALRPHLPQVGCFDTAFHGTIEATVRRYALPRHYEAMGIQRYGFHGLS
CCCCCCCHHHHHHHHCCCCCCCCCCHHHHCCHHHHHHHHHCCCCHHHHHCCHHHCCCCCC
YEHIASRLRQVSPELAAGRIVVAHLGNGASLCALHDGNSVDTTMGFSALDGLVMGTRCGA
HHHHHHHHHHCCHHHHCCCEEEEEECCCCEEEEEECCCCCCHHCCHHHHHHHHCCCCCCC
IDPGVLLYLLQEEGFSPAELQHVLYEGSGLLGVSGISSDVRELSASDDPRAREALELFAF
CCHHHEEEEEHHCCCCHHHHHHHHHCCCCEEEECCCHHHHHHHCCCCCHHHHHHHHHHHH
RAARETAALASTMGGLDGLVFTAGIGEHSASIRSAICSRLTWLGARIDHDANDSHAERIS
HHHHHHHHHHHHHCCCCCEEEEECCCCHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHH
AVDSPVDVYVIPTDEEVVIARHVLSAVGKV
HCCCCEEEEEECCCCCHHHHHHHHHHHCCC
>Mature Secondary Structure 
PNTILALNAGSSSLKFGLYEAGSSGEPRSMARGAVGLRDVRSLTAKGPDGKTLLEKELP
CCCEEEEECCCCCEEEEEEECCCCCCCHHHHHHCCCHHHHHHHHCCCCCCCHHHHHCCC
GRGLEDAIGELLRWADSWTGQGLVAAGHRIVHGGGRFSDPVLLTPPVIDAVEELTPLAPL
CCCHHHHHHHHHHHHHCCCCCCEEECCCEEEECCCCCCCCEEECCHHHHHHHHHCCCCCC
HQPRSIAPIRALTALRPHLPQVGCFDTAFHGTIEATVRRYALPRHYEAMGIQRYGFHGLS
CCCCCCCHHHHHHHHCCCCCCCCCCHHHHCCHHHHHHHHHCCCCHHHHHCCHHHCCCCCC
YEHIASRLRQVSPELAAGRIVVAHLGNGASLCALHDGNSVDTTMGFSALDGLVMGTRCGA
HHHHHHHHHHCCHHHHCCCEEEEEECCCCEEEEEECCCCCCHHCCHHHHHHHHCCCCCCC
IDPGVLLYLLQEEGFSPAELQHVLYEGSGLLGVSGISSDVRELSASDDPRAREALELFAF
CCHHHEEEEEHHCCCCHHHHHHHHHCCCCEEEECCCHHHHHHHCCCCCHHHHHHHHHHHH
RAARETAALASTMGGLDGLVFTAGIGEHSASIRSAICSRLTWLGARIDHDANDSHAERIS
HHHHHHHHHHHHHCCCCCEEEEECCCCHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHH
AVDSPVDVYVIPTDEEVVIARHVLSAVGKV
HCCCCEEEEEECCCCCHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA