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The map label for this gene is ctrA [H]

Identifier: 110634562

GI number: 110634562

Start: 2361345

End: 2362094

Strand: Reverse

Name: ctrA [H]

Synonym: Meso_2213

Alternate gene names: 110634562

Gene position: 2362094-2361345 (Counterclockwise)

Preceding gene: 110634565

Following gene: 110634559

Centisome position: 53.53

GC content: 56.4

Gene sequence:

>750_bases
ATGTTCCGTACCGGATGCCTGCCAGTCCCGGTCGGCGGCGGAAAGGGGAATAAGATGCGTGTTTTGTTGATAGAAGACGA
CAGTGCGACCGCACAGAGCATCGAACTGATGCTGAAGTCGGAAAGCTTCAATGTCTATACGACCGATCTCGGCGAAGAGG
GTGTCGATCTCGGTAAACTGTATGACTATGACATCATCCTTCTCGATCTGAACCTGCCGGACATGTCCGGCTACGAAGTC
TTGAGAACCCTTCGCCTTTCTAAAGTGAAGACGCCGATCCTCATCCTCTCCGGCATGGCCGGAATAGAAGACAAGGTGAG
GGGCCTTGGCTTCGGCGCCGACGACTACATGACCAAGCCCTTCCACAAGGACGAGCTGATTGCACGCATTCATGCGATTG
TCCGCCGCTCAAAAGGCCATGCGCAGTCGGTTATCACGACGGGCGATCTGATCGTCAATCTCGACGCCAAGACCGTCGAG
GTCGGCGGGCAGCGGGTGCACCTGACCGGCAAGGAATATCAGATGCTGGAGCTGCTCTCCCTTCGCAAGGGCACGACGCT
GACGAAGGAGATGTTCCTCAACCATCTTTACGGCGGCATGGACGAGCCGGAATTGAAGATTATCGACGTCTTCATCTGCA
AGCTTCGCAAGAAGCTCGATATGGCCTCGGGCGGCCAGAACTATATCGAGACCGTCTGGGGCCGCGGTTATGTGCTGCGT
GAACCGGAGGAAGTTCGCGAGAGCGCCTGA

Upstream 100 bases:

>100_bases
CAAATAGGTGTCAGCGAATGCTGAAAAAAGCGCTTAGCGCTTTGAGGGGCGAATCAGATATTGTTAACCATTAAATGGCA
GCTTGCGATCCGGGTGCTCA

Downstream 100 bases:

>100_bases
GCCGGCTTATACCCAAAGAAGCAAAGAACCCGGCCAATGCCGGGTTTTTGTTTTCAGGTCGTGGCCAGATACTCTCGGAA
ACTTTCCAGGAGCTGCGGCC

Product: two component transcriptional regulator / cell cycle transcriptional regulator CtrA

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 249; Mature: 249

Protein sequence:

>249_residues
MFRTGCLPVPVGGGKGNKMRVLLIEDDSATAQSIELMLKSESFNVYTTDLGEEGVDLGKLYDYDIILLDLNLPDMSGYEV
LRTLRLSKVKTPILILSGMAGIEDKVRGLGFGADDYMTKPFHKDELIARIHAIVRRSKGHAQSVITTGDLIVNLDAKTVE
VGGQRVHLTGKEYQMLELLSLRKGTTLTKEMFLNHLYGGMDEPELKIIDVFICKLRKKLDMASGGQNYIETVWGRGYVLR
EPEEVRESA

Sequences:

>Translated_249_residues
MFRTGCLPVPVGGGKGNKMRVLLIEDDSATAQSIELMLKSESFNVYTTDLGEEGVDLGKLYDYDIILLDLNLPDMSGYEV
LRTLRLSKVKTPILILSGMAGIEDKVRGLGFGADDYMTKPFHKDELIARIHAIVRRSKGHAQSVITTGDLIVNLDAKTVE
VGGQRVHLTGKEYQMLELLSLRKGTTLTKEMFLNHLYGGMDEPELKIIDVFICKLRKKLDMASGGQNYIETVWGRGYVLR
EPEEVRESA
>Mature_249_residues
MFRTGCLPVPVGGGKGNKMRVLLIEDDSATAQSIELMLKSESFNVYTTDLGEEGVDLGKLYDYDIILLDLNLPDMSGYEV
LRTLRLSKVKTPILILSGMAGIEDKVRGLGFGADDYMTKPFHKDELIARIHAIVRRSKGHAQSVITTGDLIVNLDAKTVE
VGGQRVHLTGKEYQMLELLSLRKGTTLTKEMFLNHLYGGMDEPELKIIDVFICKLRKKLDMASGGQNYIETVWGRGYVLR
EPEEVRESA

Specific function: Essential protein that plays a role in the control of cell division, possibly through the transcriptional regulation of ccrM, rpoD, pleC, minC and ftsZ genes [H]

COG id: COG0745

COG function: function code TK; Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 response regulatory domain [H]

Homologues:

Organism=Escherichia coli, GI1790552, Length=229, Percent_Identity=36.2445414847162, Blast_Score=144, Evalue=7e-36,
Organism=Escherichia coli, GI1786784, Length=226, Percent_Identity=34.9557522123894, Blast_Score=137, Evalue=5e-34,
Organism=Escherichia coli, GI1789402, Length=223, Percent_Identity=34.5291479820628, Blast_Score=130, Evalue=7e-32,
Organism=Escherichia coli, GI1787375, Length=221, Percent_Identity=33.9366515837104, Blast_Score=129, Evalue=2e-31,
Organism=Escherichia coli, GI87082012, Length=220, Percent_Identity=33.6363636363636, Blast_Score=120, Evalue=6e-29,
Organism=Escherichia coli, GI2367329, Length=228, Percent_Identity=32.0175438596491, Blast_Score=110, Evalue=8e-26,
Organism=Escherichia coli, GI1786911, Length=219, Percent_Identity=30.5936073059361, Blast_Score=109, Evalue=2e-25,
Organism=Escherichia coli, GI1786599, Length=221, Percent_Identity=31.2217194570136, Blast_Score=109, Evalue=2e-25,
Organism=Escherichia coli, GI1789809, Length=227, Percent_Identity=29.5154185022026, Blast_Score=107, Evalue=5e-25,
Organism=Escherichia coli, GI1788394, Length=224, Percent_Identity=31.25, Blast_Score=107, Evalue=7e-25,
Organism=Escherichia coli, GI1790860, Length=222, Percent_Identity=30.1801801801802, Blast_Score=105, Evalue=3e-24,
Organism=Escherichia coli, GI1787229, Length=227, Percent_Identity=29.9559471365639, Blast_Score=100, Evalue=8e-23,
Organism=Escherichia coli, GI1790863, Length=227, Percent_Identity=25.5506607929515, Blast_Score=86, Evalue=3e-18,
Organism=Escherichia coli, GI1788550, Length=118, Percent_Identity=27.9661016949153, Blast_Score=69, Evalue=4e-13,
Organism=Escherichia coli, GI1790437, Length=164, Percent_Identity=24.390243902439, Blast_Score=68, Evalue=7e-13,
Organism=Escherichia coli, GI1789149, Length=155, Percent_Identity=27.0967741935484, Blast_Score=62, Evalue=4e-11,
Organism=Escherichia coli, GI145693140, Length=236, Percent_Identity=25.4237288135593, Blast_Score=60, Evalue=9e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011006
- InterPro:   IPR001867
- InterPro:   IPR001789
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00072 Response_reg; PF00486 Trans_reg_C [H]

EC number: NA

Molecular weight: Translated: 27754; Mature: 27754

Theoretical pI: Translated: 6.05; Mature: 6.05

Prosite motif: PS50110 RESPONSE_REGULATORY

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
4.0 %Met     (Translated Protein)
4.8 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
4.0 %Met     (Mature Protein)
4.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MFRTGCLPVPVGGGKGNKMRVLLIEDDSATAQSIELMLKSESFNVYTTDLGEEGVDLGKL
CCCCCCEEECCCCCCCCEEEEEEEECCCCCHHHEEEEEECCCCEEEECCCCCCCCCCCEE
YDYDIILLDLNLPDMSGYEVLRTLRLSKVKTPILILSGMAGIEDKVRGLGFGADDYMTKP
ECEEEEEEEECCCCCCHHHHHHHHHHHHCCCCEEEEECCCCCHHHHHHCCCCCHHCCCCC
FHKDELIARIHAIVRRSKGHAQSVITTGDLIVNLDAKTVEVGGQRVHLTGKEYQMLELLS
CCHHHHHHHHHHHHHCCCCCHHEEEEECCEEEECCCEEEEECCCEEEEECCCHHHHHHHH
LRKGTTLTKEMFLNHLYGGMDEPELKIIDVFICKLRKKLDMASGGQNYIETVWGRGYVLR
HCCCCHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHCCCCCCCHHHHHHHCCCEEEE
EPEEVRESA
CHHHHHHCC
>Mature Secondary Structure
MFRTGCLPVPVGGGKGNKMRVLLIEDDSATAQSIELMLKSESFNVYTTDLGEEGVDLGKL
CCCCCCEEECCCCCCCCEEEEEEEECCCCCHHHEEEEEECCCCEEEECCCCCCCCCCCEE
YDYDIILLDLNLPDMSGYEVLRTLRLSKVKTPILILSGMAGIEDKVRGLGFGADDYMTKP
ECEEEEEEEECCCCCCHHHHHHHHHHHHCCCCEEEEECCCCCHHHHHHCCCCCHHCCCCC
FHKDELIARIHAIVRRSKGHAQSVITTGDLIVNLDAKTVEVGGQRVHLTGKEYQMLELLS
CCHHHHHHHHHHHHHCCCCCHHEEEEECCEEEECCCEEEEECCCEEEEECCCHHHHHHHH
LRKGTTLTKEMFLNHLYGGMDEPELKIIDVFICKLRKKLDMASGGQNYIETVWGRGYVLR
HCCCCHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHCCCCCCCHHHHHHHCCCEEEE
EPEEVRESA
CHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA