Click here to switch to the map view.

The map label for this gene is nudL [H]

Identifier: 110634526

GI number: 110634526

Start: 2325605

End: 2326240

Strand: Reverse

Name: nudL [H]

Synonym: Meso_2177

Alternate gene names: 110634526

Gene position: 2326240-2325605 (Counterclockwise)

Preceding gene: 110634527

Following gene: 110634525

Centisome position: 52.72

GC content: 61.79

Gene sequence:

>636_bases
ATGAGCACTCAGGACGTCTCCCTCTTTTCGGCCGAGGACTTCCGGCGGCGGGCCGCGGCCCAGGATCCCGCGCTGGCGGG
CGAGGCCTATGGCGACCACCGGCTGAATCCGGATTTGAAGCAGTTTTTCCTGCGCGACGGGCTGCATGACGCTGCCGTGC
TTGTTCCAGTGGTGAACCATGCGGGCGGGGCGACGGTCATCCTTACGGAACGGTCGAGCCGCTTGCGGCAGCATTCGGGA
CAGATCGCCTTTCCTGGCGGGCGCATAGATCCGACCGATTCCTCGCCTGAGGATGCGGCACTTCGCGAGGCGGAGGAGGA
GATCGGGCTTGACCGGGCCCTTATCCAGGTCGTCGGGCGCATGCCCGATTATGTCACCGGCAGTGGCTATCGCATCCGCC
CGGTGCTTTCGGTGGTGCAATCCGATTTTGCCCTGGTTCTGAACACCGACGAGGTGGAGGATGCCTTCGAGGTGCCGCTT
TCCTTCCTGATGGACCCTGCCAATCATCGGCGCGAAAGCCGCATTTGGCAGGAGAGGGAACGCTTTTTCTACACAATGCC
TTACGGCGAGCGCTTCATATGGGGAATCACCGCCGGCATTCTGCATATGCTTTATGAAAGGCTCTATGCCCGATGA

Upstream 100 bases:

>100_bases
GTGAAGAAATGCATATCGGCGGCAGACGCATGTTTGCTGTCCGCTCCAGGGGCAAGGCCTTTCCCGTAATGTCCATGGAA
GAACTGGAGGGCTCACTCGC

Downstream 100 bases:

>100_bases
CCACGATCGCCGGTGCTCCCTGGCTCGATCAGCAGGGCCTTCAGCCACTGCTGGAAATCCTCAACGAAGGCGGGGAAGAA
GCCCGCATCGCAGGCGGCGC

Product: NUDIX hydrolase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 211; Mature: 210

Protein sequence:

>211_residues
MSTQDVSLFSAEDFRRRAAAQDPALAGEAYGDHRLNPDLKQFFLRDGLHDAAVLVPVVNHAGGATVILTERSSRLRQHSG
QIAFPGGRIDPTDSSPEDAALREAEEEIGLDRALIQVVGRMPDYVTGSGYRIRPVLSVVQSDFALVLNTDEVEDAFEVPL
SFLMDPANHRRESRIWQERERFFYTMPYGERFIWGITAGILHMLYERLYAR

Sequences:

>Translated_211_residues
MSTQDVSLFSAEDFRRRAAAQDPALAGEAYGDHRLNPDLKQFFLRDGLHDAAVLVPVVNHAGGATVILTERSSRLRQHSG
QIAFPGGRIDPTDSSPEDAALREAEEEIGLDRALIQVVGRMPDYVTGSGYRIRPVLSVVQSDFALVLNTDEVEDAFEVPL
SFLMDPANHRRESRIWQERERFFYTMPYGERFIWGITAGILHMLYERLYAR
>Mature_210_residues
STQDVSLFSAEDFRRRAAAQDPALAGEAYGDHRLNPDLKQFFLRDGLHDAAVLVPVVNHAGGATVILTERSSRLRQHSGQ
IAFPGGRIDPTDSSPEDAALREAEEEIGLDRALIQVVGRMPDYVTGSGYRIRPVLSVVQSDFALVLNTDEVEDAFEVPLS
FLMDPANHRRESRIWQERERFFYTMPYGERFIWGITAGILHMLYERLYAR

Specific function: Probably mediates the hydrolysis of some nucleoside diphosphate derivatives [H]

COG id: COG0494

COG function: function code LR; NTP pyrophosphohydrolases including oxidative damage repair enzymes

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 nudix hydrolase domain [H]

Homologues:

Organism=Homo sapiens, GI157785656, Length=145, Percent_Identity=33.7931034482759, Blast_Score=86, Evalue=2e-17,
Organism=Escherichia coli, GI1788115, Length=162, Percent_Identity=38.2716049382716, Blast_Score=87, Evalue=1e-18,
Organism=Caenorhabditis elegans, GI17536993, Length=173, Percent_Identity=28.9017341040462, Blast_Score=84, Evalue=4e-17,
Organism=Caenorhabditis elegans, GI17510677, Length=128, Percent_Identity=34.375, Blast_Score=67, Evalue=8e-12,
Organism=Drosophila melanogaster, GI18859683, Length=164, Percent_Identity=42.6829268292683, Blast_Score=94, Evalue=6e-20,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000086
- InterPro:   IPR015797
- InterPro:   IPR000059 [H]

Pfam domain/function: PF00293 NUDIX [H]

EC number: NA

Molecular weight: Translated: 23823; Mature: 23692

Theoretical pI: Translated: 4.97; Mature: 4.97

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
2.4 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
1.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSTQDVSLFSAEDFRRRAAAQDPALAGEAYGDHRLNPDLKQFFLRDGLHDAAVLVPVVNH
CCCCCCHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCHHHHHHHHHCCCCHHHHHHHHHHC
AGGATVILTERSSRLRQHSGQIAFPGGRIDPTDSSPEDAALREAEEEIGLDRALIQVVGR
CCCEEEEEECCHHHHHHHCCCEECCCCCCCCCCCCCHHHHHHHHHHHHCHHHHHHHHHHC
MPDYVTGSGYRIRPVLSVVQSDFALVLNTDEVEDAFEVPLSFLMDPANHRRESRIWQERE
CCCCCCCCCEEHHHHHHHHHCCCEEEEECCHHHHHHHHHHHHHHCCHHHHHHHHHHHHHH
RFFYTMPYGERFIWGITAGILHMLYERLYAR
HEEEECCCCCCHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure 
STQDVSLFSAEDFRRRAAAQDPALAGEAYGDHRLNPDLKQFFLRDGLHDAAVLVPVVNH
CCCCCHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCHHHHHHHHHCCCCHHHHHHHHHHC
AGGATVILTERSSRLRQHSGQIAFPGGRIDPTDSSPEDAALREAEEEIGLDRALIQVVGR
CCCEEEEEECCHHHHHHHCCCEECCCCCCCCCCCCCHHHHHHHHHHHHCHHHHHHHHHHC
MPDYVTGSGYRIRPVLSVVQSDFALVLNTDEVEDAFEVPLSFLMDPANHRRESRIWQERE
CCCCCCCCCEEHHHHHHHHHCCCEEEEECCHHHHHHHHHHHHHHCCHHHHHHHHHHHHHH
RFFYTMPYGERFIWGITAGILHMLYERLYAR
HEEEECCCCCCHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA