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The map label for this gene is ilvE [H]

Identifier: 110634489

GI number: 110634489

Start: 2293635

End: 2294603

Strand: Reverse

Name: ilvE [H]

Synonym: Meso_2140

Alternate gene names: 110634489

Gene position: 2294603-2293635 (Counterclockwise)

Preceding gene: 110634495

Following gene: 110634488

Centisome position: 52.0

GC content: 59.96

Gene sequence:

>969_bases
ATGTTCCGGCATAATCCGGTTTTCGCCCGCACTTGTGGGTTTTTTCCAGGGCAAAGGGCCCGAAGGAGACTTAGGATGGC
ATCTGTTCCTTTCGATCAGCTGGATGGCTTCATCTGGATGAACGGCGAGTTCGTAGAGTGGGCGGATGCCAAGATTCACG
TGCTCACCCACGGCCTGCATTACGCAAGCGCCGTATTCGAGGGCGAGCGCGCCTATGGCGGGCAGATCTTCAAGCTGACT
GAGCATTCGGAGCGGCTGCACGAATCCGCGCGCGTCATGGGGTTCCGCATTCCCTACACGGTCGCCGAGATCGATGAGGC
ATGCCGGCAGCTTCTCGCCAAGCAAGGGCTGCAAGACGCCTATGTGCGTCCGATCGCCTGGCGCGGCAGCGAGATGATGG
GCGTTTCAGCTCAGAACAACCGCATCAATCTCGCAATCGCCATCTGGGAATGGCCGAGCTATTTCAACCCCGAACAGCGG
CTCAAGGGCATTCGCCTCGATATGGCCGAATACCGCCGGCCGGATCCGCGTACGGCGCCTTGGAAAGCGAAGGCCGCGGG
GCTTTATATGATCTGCACGCTTTCCAAGCATGCGGCGGAGGCTAAGGGCTACAGTGATGCGCTGATGCTTGATTGGCGCG
GACAGGTGGCTGAGGCCACCGGCGCCAATGTCTTTTTCGTCAAGGACGGAAAGCTGCATACGCCGGCTCCCGATTGCTTC
CTGGATGGAATCACCCGGCGCACCGTGATCGATCTGGCGCGCCGGCGCGGCATCGAGGTGGTTGAAAGGGCGATCCAGCC
GGAGGAGCTGACGGGCTTTGAACAATGCTTCCTCACGGGAAGCGCGGCGGAGGTGACGCCTGTCTCCGAGATCGGGCCTT
ATAACTTCCAAGTGGGTGAAATCACTCGCGTTTTGATGGAGGATTACTCCGAGGAAGTGCGCCCGAGGCAGCGTCTCGCA
GCAGAATAA

Upstream 100 bases:

>100_bases
TGCCAAGCTTTACGCCTTATAGCGAACAAAAAGAGCGTGTTGAGACTGTTTTTCCGGAACTTTCCTCAGGTTGGGCCAAA
ACGGTTTGCTACGGGAAGTG

Downstream 100 bases:

>100_bases
GGACGCCTGGTCCGCGCTGATGCGCGCGGGCGGAATCCTCTCCTGATTTGACTTTGATCGAATTCGGCGTTTCATGATGA
CGCCGGCACAATAAGGTCGG

Product: branched-chain amino acid aminotransferase

Products: NA

Alternate protein names: BCAT [H]

Number of amino acids: Translated: 322; Mature: 322

Protein sequence:

>322_residues
MFRHNPVFARTCGFFPGQRARRRLRMASVPFDQLDGFIWMNGEFVEWADAKIHVLTHGLHYASAVFEGERAYGGQIFKLT
EHSERLHESARVMGFRIPYTVAEIDEACRQLLAKQGLQDAYVRPIAWRGSEMMGVSAQNNRINLAIAIWEWPSYFNPEQR
LKGIRLDMAEYRRPDPRTAPWKAKAAGLYMICTLSKHAAEAKGYSDALMLDWRGQVAEATGANVFFVKDGKLHTPAPDCF
LDGITRRTVIDLARRRGIEVVERAIQPEELTGFEQCFLTGSAAEVTPVSEIGPYNFQVGEITRVLMEDYSEEVRPRQRLA
AE

Sequences:

>Translated_322_residues
MFRHNPVFARTCGFFPGQRARRRLRMASVPFDQLDGFIWMNGEFVEWADAKIHVLTHGLHYASAVFEGERAYGGQIFKLT
EHSERLHESARVMGFRIPYTVAEIDEACRQLLAKQGLQDAYVRPIAWRGSEMMGVSAQNNRINLAIAIWEWPSYFNPEQR
LKGIRLDMAEYRRPDPRTAPWKAKAAGLYMICTLSKHAAEAKGYSDALMLDWRGQVAEATGANVFFVKDGKLHTPAPDCF
LDGITRRTVIDLARRRGIEVVERAIQPEELTGFEQCFLTGSAAEVTPVSEIGPYNFQVGEITRVLMEDYSEEVRPRQRLA
AE
>Mature_322_residues
MFRHNPVFARTCGFFPGQRARRRLRMASVPFDQLDGFIWMNGEFVEWADAKIHVLTHGLHYASAVFEGERAYGGQIFKLT
EHSERLHESARVMGFRIPYTVAEIDEACRQLLAKQGLQDAYVRPIAWRGSEMMGVSAQNNRINLAIAIWEWPSYFNPEQR
LKGIRLDMAEYRRPDPRTAPWKAKAAGLYMICTLSKHAAEAKGYSDALMLDWRGQVAEATGANVFFVKDGKLHTPAPDCF
LDGITRRTVIDLARRRGIEVVERAIQPEELTGFEQCFLTGSAAEVTPVSEIGPYNFQVGEITRVLMEDYSEEVRPRQRLA
AE

Specific function: Acts on leucine, isoleucine and valine [H]

COG id: COG0115

COG function: function code EH; Branched-chain amino acid aminotransferase/4-amino-4-deoxychorismate lyase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family [H]

Homologues:

Organism=Escherichia coli, GI48994963, Length=270, Percent_Identity=40, Blast_Score=198, Evalue=3e-52,
Organism=Caenorhabditis elegans, GI17565728, Length=327, Percent_Identity=25.9938837920489, Blast_Score=65, Evalue=4e-11,

Paralogues:

None

Copy number: 2342 Molecules/Cell In: Growth Phase, Glucose-minimal MOPS Media. 11,000 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001544
- InterPro:   IPR018300 [H]

Pfam domain/function: PF01063 Aminotran_4 [H]

EC number: =2.6.1.42 [H]

Molecular weight: Translated: 36631; Mature: 36631

Theoretical pI: Translated: 7.57; Mature: 7.57

Prosite motif: PS00770 AA_TRANSFER_CLASS_4

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.6 %Cys     (Translated Protein)
3.1 %Met     (Translated Protein)
4.7 %Cys+Met (Translated Protein)
1.6 %Cys     (Mature Protein)
3.1 %Met     (Mature Protein)
4.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MFRHNPVFARTCGFFPGQRARRRLRMASVPFDQLDGFIWMNGEFVEWADAKIHVLTHGLH
CCCCCCCHHHHCCCCCCHHHHHHHHHHCCCHHHCCCEEEECCCEEEECCCEEEEEECCHH
YASAVFEGERAYGGQIFKLTEHSERLHESARVMGFRIPYTVAEIDEACRQLLAKQGLQDA
HHHHHHCCCCCCCCEEEEECHHHHHHHHHHHHEEEECCCHHHHHHHHHHHHHHHCCCHHH
YVRPIAWRGSEMMGVSAQNNRINLAIAIWEWPSYFNPEQRLKGIRLDMAEYRRPDPRTAP
HCCCEEECCCCEEEEECCCCEEEEEEEEEECCCCCCHHHHHCCCEECHHHHCCCCCCCCC
WKAKAAGLYMICTLSKHAAEAKGYSDALMLDWRGQVAEATGANVFFVKDGKLHTPAPDCF
CCCCCCCEEEEEECCHHHHHCCCCCCEEEEECCCCCHHCCCCEEEEEECCEECCCCCHHH
LDGITRRTVIDLARRRGIEVVERAIQPEELTGFEQCFLTGSAAEVTPVSEIGPYNFQVGE
HHCCHHHHHHHHHHHCCHHHHHHHCCCHHCCCHHHHEECCCCCCCCCHHHCCCCCCCHHH
ITRVLMEDYSEEVRPRQRLAAE
HHHHHHHHHHHHHCHHHHHCCC
>Mature Secondary Structure
MFRHNPVFARTCGFFPGQRARRRLRMASVPFDQLDGFIWMNGEFVEWADAKIHVLTHGLH
CCCCCCCHHHHCCCCCCHHHHHHHHHHCCCHHHCCCEEEECCCEEEECCCEEEEEECCHH
YASAVFEGERAYGGQIFKLTEHSERLHESARVMGFRIPYTVAEIDEACRQLLAKQGLQDA
HHHHHHCCCCCCCCEEEEECHHHHHHHHHHHHEEEECCCHHHHHHHHHHHHHHHCCCHHH
YVRPIAWRGSEMMGVSAQNNRINLAIAIWEWPSYFNPEQRLKGIRLDMAEYRRPDPRTAP
HCCCEEECCCCEEEEECCCCEEEEEEEEEECCCCCCHHHHHCCCEECHHHHCCCCCCCCC
WKAKAAGLYMICTLSKHAAEAKGYSDALMLDWRGQVAEATGANVFFVKDGKLHTPAPDCF
CCCCCCCEEEEEECCHHHHHCCCCCCEEEEECCCCCHHCCCCEEEEEECCEECCCCCHHH
LDGITRRTVIDLARRRGIEVVERAIQPEELTGFEQCFLTGSAAEVTPVSEIGPYNFQVGE
HHCCHHHHHHHHHHHCCHHHHHHHCCCHHCCCHHHHEECCCCCCCCCHHHCCCCCCCHHH
ITRVLMEDYSEEVRPRQRLAAE
HHHHHHHHHHHHHCHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA