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The map label for this gene is uvrB [H]

Identifier: 110634481

GI number: 110634481

Start: 2286136

End: 2288922

Strand: Reverse

Name: uvrB [H]

Synonym: Meso_2132

Alternate gene names: 110634481

Gene position: 2288922-2286136 (Counterclockwise)

Preceding gene: 110634482

Following gene: 110634480

Centisome position: 51.87

GC content: 64.76

Gene sequence:

>2787_bases
ATGGCCAACTCTCCGAGAAAGAATACCGGTGGCTTCCGTGAGTCACCCCAGCCCCCGCTGTCAGGCACGCCGCTTTCCGC
TTCCATTTCCGATTGGGCGGCCGATATCGCGCGTGAGGCGGAGAAGCCGGCCAAGCCACGAAAGAAGATTCCCGAGCGCT
CCGCGGCGCCGGGCAGAACCGGCCGCGGCACCTCAATGGGAGGCGCTGCCTCGGCGCGCGATCGCGCGGCCGCTGGGCTG
ATGCCCATCGCGGGCCTGGATGTTACACTTGAGGAGGCGGAGCGGATCGCCCCTGGTGGCGTTACGGCCACCGTCGCGGC
ACTGTCGAACCTTATCGAGGGCGGCGACCCCAACCTGAAATCCGCCTGGGTGCCGCACCGCCCCCCGCGGCCGGAAAAAT
CCGAGGGTGGTATCCCCTTCCGGATGGCGACGGAATTCAAGCCCTCGGGCGACCAGCCGACAGCTATCCGCGATCTGGTC
GAGGGCATCAGCACCAGCGAGCGCACGCAGGTGCTGCTGGGCGTCACCGGCAGTGGAAAAACCTTCACCATGGCCAAGGT
GATCGAGGAGACGCAACGCCCGGCGCTCATCCTCGCCCCTAACAAAACGCTGGCCGCCCAGCTCTATGGCGAGTTCAAGT
CCTTTTTCCCGGACAACGCGGTCGAGTACTTCGTCTCCTATTACGACTATTACCAGCCGGAGGCCTACGTCCCGCGTTCG
GACACCTATATCGAGAAGGAATCTTCCATCAACGAGCAGATCGACCGGATGCGCCACTCGGCCACTCGCGCCCTGCTCGA
ACGCGACGACGTCATCATCGTCGCTTCCGTTTCCTGCATCTACGGTATCGGCTCGGTCGAGACCTACACGGCCATGACCT
TCCAGATGGCGGTGGGCGACCGGCTCGACCAGCGCCAGCTTCTGGCCGACCTCGTCGAACAGCAATACAAGCGCCGCGAC
GCCGATTTCACCCGCGGCTCCTTCCGCGTGCGCGGCGACACGATCGAGATCTTCCCGGCCCACCTTGAGGATCGCGCCTG
GCGCATTTCGCTCTTCGGCGACGAGATCGAGGCTATCACCGAGTTCGACCCGCTCACCGGCAAGAAGACCGACGACCTCA
AGTCGGTCAAGATTTACGCCAACTCGCATTACGTCACCCCGCGCCCCACGCTCAATCAGGCCATCCGGCAAATCAAGGAG
GAGCTGAAGCTGCGCCTCGTGGAGCTGGAAAAAGCCGGGCGCCTGCTGGAAGCCCAGCGTCTTGAACAGCGCACGCGCTT
CGATCTCGAAATGCTGGAGGCCACCGGCTCCTGCGCCGGGATCGAGAACTATTCGCGCTATCTCACCGGACGCAATCCAG
GCGAGCCGCCGCCAACGCTCTTCGAATACGTGCCGGACAACGCGCTCGTTTTTGTCGACGAATCCCATGTCACCGTGCCG
CAGATCGGCGCCATGTACCGGGGCGACTTTCGTCGCAAGGCCACGCTTGCCGAGTATGGTTTCCGCCTGCCGTCATGCAT
GGACAACCGGCCGCTGCGCTTCGAGGAATGGGATGCCATGCGCCCGCTCACCGTCGCGGTGTCGGCCACGCCCGGCAATT
GGGAGATGGAGCAGTCGGGCGGCGTCTTCGCCGAGCAGGTCATCCGCCCCACCGGCCTTATCGATCCGCCGGTCGAGATT
CGTCCGGCCAAGTCCCAAGTCGACGACGTTCTGGGCGAGATCCGGGAGACCACCAAAGCTGGCTACCGAACCCTCGTCAC
CGTGCTGACGAAGCGCATGGCTGAGGACCTTACCGAATATCTGCACGAGCAGGGCATCCGCGTACGCTATATGCACTCCG
ACATCGACACGCTGGAGCGCATCGAGATCATCCGCGACCTCCGCCTCGGCGCCTTCGACGTGCTGGTGGGCATCAATCTT
TTGCGTGAGGGCCTGGATATTCCGGAATGCGGCCTCGTCGCAATTCTGGACGCGGACAAGGAAGGATTCCTGCGTTCTGA
AACCTCGCTCGTCCAGACCATCGGCCGCGCGGCGCGCAATGTCGATGGCCGCGTCATCCTCTATGCCGATCACATCACCG
GCTCGATGGAGCGCGCGATCGCCGAGACGAACCGCCGCCGTGAGAAGCAGCTCGAATATAACGCGGGGAACGGCATCACG
CCGGAATCGATCAAGAAGAACATCGGCGACATCCTCGGCTCCGTCTACGAGCGCGACCACGTGCGCGCCGAGATCGGCGG
CGCCAAGGGCGACGACCTGAACAATCTCGTCGGCAACAATCTCCAGGCCCATCTTGAATATCTTGAGAAGGCCATGCGGG
ATGCCGCCGCCGACCTCGATTTCGAGGAGGCGGCCCGCCTGCGCGACGAGATCAAGCGCCTGCGGGAGACGGAGCTTGCG
CTTCTGGACGACCCCATGTCGCGCGACGCGGGCGTGGAGAACACGCGGGACCGCCGCCGTCAGGCCGCAAAGGGCAGGGG
CTCTGCCGCGTCGCCGAAAGGCAGCCCGGATAGGCCTCTCTTCCGCAAGCCGGAACTGGACGAGATGGGCAGTTCGGGAG
CCCACGCGGTTCCCGCTGGCCAGACCCTCTTCCGGAAGAACTCGTTGGACGAGATGACCGTGCGGCGCACGGAGAAGCCG
GTCGGCAAGACGCTGCCGGCCACGCCTCCCGACGAGGATCTCATCGCGCCCCGCCGGAGCAAGGTCGGCGCAGGTTCCTA
CGAGGATCCGGCCGACGAGCGCCAGCGTAAGCGCCGGTCACGGAAGACCGGCAGGCCCGGGCAGTAG

Upstream 100 bases:

>100_bases
GACCTTCCTGACAGCCTCCTGTCAGCAGCAGCGGCATGGAGTTTCCTGCTCGGCCTCCTGCCCCTTTCCATTTGCGCCGC
CAACCTCCATATTCGTCGCC

Downstream 100 bases:

>100_bases
GCGCGCGGCGCCCCCCTTCGGGGGCGCATAACTCCCGGTTGATTTCTCAATCCTGCCGCGGCGTTCCACGATGCTGCTTT
TGAAAGCTAAATGCCGCGGT

Product: excinuclease ABC subunit B

Products: NA

Alternate protein names: Protein uvrB; Excinuclease ABC subunit B [H]

Number of amino acids: Translated: 928; Mature: 927

Protein sequence:

>928_residues
MANSPRKNTGGFRESPQPPLSGTPLSASISDWAADIAREAEKPAKPRKKIPERSAAPGRTGRGTSMGGAASARDRAAAGL
MPIAGLDVTLEEAERIAPGGVTATVAALSNLIEGGDPNLKSAWVPHRPPRPEKSEGGIPFRMATEFKPSGDQPTAIRDLV
EGISTSERTQVLLGVTGSGKTFTMAKVIEETQRPALILAPNKTLAAQLYGEFKSFFPDNAVEYFVSYYDYYQPEAYVPRS
DTYIEKESSINEQIDRMRHSATRALLERDDVIIVASVSCIYGIGSVETYTAMTFQMAVGDRLDQRQLLADLVEQQYKRRD
ADFTRGSFRVRGDTIEIFPAHLEDRAWRISLFGDEIEAITEFDPLTGKKTDDLKSVKIYANSHYVTPRPTLNQAIRQIKE
ELKLRLVELEKAGRLLEAQRLEQRTRFDLEMLEATGSCAGIENYSRYLTGRNPGEPPPTLFEYVPDNALVFVDESHVTVP
QIGAMYRGDFRRKATLAEYGFRLPSCMDNRPLRFEEWDAMRPLTVAVSATPGNWEMEQSGGVFAEQVIRPTGLIDPPVEI
RPAKSQVDDVLGEIRETTKAGYRTLVTVLTKRMAEDLTEYLHEQGIRVRYMHSDIDTLERIEIIRDLRLGAFDVLVGINL
LREGLDIPECGLVAILDADKEGFLRSETSLVQTIGRAARNVDGRVILYADHITGSMERAIAETNRRREKQLEYNAGNGIT
PESIKKNIGDILGSVYERDHVRAEIGGAKGDDLNNLVGNNLQAHLEYLEKAMRDAAADLDFEEAARLRDEIKRLRETELA
LLDDPMSRDAGVENTRDRRRQAAKGRGSAASPKGSPDRPLFRKPELDEMGSSGAHAVPAGQTLFRKNSLDEMTVRRTEKP
VGKTLPATPPDEDLIAPRRSKVGAGSYEDPADERQRKRRSRKTGRPGQ

Sequences:

>Translated_928_residues
MANSPRKNTGGFRESPQPPLSGTPLSASISDWAADIAREAEKPAKPRKKIPERSAAPGRTGRGTSMGGAASARDRAAAGL
MPIAGLDVTLEEAERIAPGGVTATVAALSNLIEGGDPNLKSAWVPHRPPRPEKSEGGIPFRMATEFKPSGDQPTAIRDLV
EGISTSERTQVLLGVTGSGKTFTMAKVIEETQRPALILAPNKTLAAQLYGEFKSFFPDNAVEYFVSYYDYYQPEAYVPRS
DTYIEKESSINEQIDRMRHSATRALLERDDVIIVASVSCIYGIGSVETYTAMTFQMAVGDRLDQRQLLADLVEQQYKRRD
ADFTRGSFRVRGDTIEIFPAHLEDRAWRISLFGDEIEAITEFDPLTGKKTDDLKSVKIYANSHYVTPRPTLNQAIRQIKE
ELKLRLVELEKAGRLLEAQRLEQRTRFDLEMLEATGSCAGIENYSRYLTGRNPGEPPPTLFEYVPDNALVFVDESHVTVP
QIGAMYRGDFRRKATLAEYGFRLPSCMDNRPLRFEEWDAMRPLTVAVSATPGNWEMEQSGGVFAEQVIRPTGLIDPPVEI
RPAKSQVDDVLGEIRETTKAGYRTLVTVLTKRMAEDLTEYLHEQGIRVRYMHSDIDTLERIEIIRDLRLGAFDVLVGINL
LREGLDIPECGLVAILDADKEGFLRSETSLVQTIGRAARNVDGRVILYADHITGSMERAIAETNRRREKQLEYNAGNGIT
PESIKKNIGDILGSVYERDHVRAEIGGAKGDDLNNLVGNNLQAHLEYLEKAMRDAAADLDFEEAARLRDEIKRLRETELA
LLDDPMSRDAGVENTRDRRRQAAKGRGSAASPKGSPDRPLFRKPELDEMGSSGAHAVPAGQTLFRKNSLDEMTVRRTEKP
VGKTLPATPPDEDLIAPRRSKVGAGSYEDPADERQRKRRSRKTGRPGQ
>Mature_927_residues
ANSPRKNTGGFRESPQPPLSGTPLSASISDWAADIAREAEKPAKPRKKIPERSAAPGRTGRGTSMGGAASARDRAAAGLM
PIAGLDVTLEEAERIAPGGVTATVAALSNLIEGGDPNLKSAWVPHRPPRPEKSEGGIPFRMATEFKPSGDQPTAIRDLVE
GISTSERTQVLLGVTGSGKTFTMAKVIEETQRPALILAPNKTLAAQLYGEFKSFFPDNAVEYFVSYYDYYQPEAYVPRSD
TYIEKESSINEQIDRMRHSATRALLERDDVIIVASVSCIYGIGSVETYTAMTFQMAVGDRLDQRQLLADLVEQQYKRRDA
DFTRGSFRVRGDTIEIFPAHLEDRAWRISLFGDEIEAITEFDPLTGKKTDDLKSVKIYANSHYVTPRPTLNQAIRQIKEE
LKLRLVELEKAGRLLEAQRLEQRTRFDLEMLEATGSCAGIENYSRYLTGRNPGEPPPTLFEYVPDNALVFVDESHVTVPQ
IGAMYRGDFRRKATLAEYGFRLPSCMDNRPLRFEEWDAMRPLTVAVSATPGNWEMEQSGGVFAEQVIRPTGLIDPPVEIR
PAKSQVDDVLGEIRETTKAGYRTLVTVLTKRMAEDLTEYLHEQGIRVRYMHSDIDTLERIEIIRDLRLGAFDVLVGINLL
REGLDIPECGLVAILDADKEGFLRSETSLVQTIGRAARNVDGRVILYADHITGSMERAIAETNRRREKQLEYNAGNGITP
ESIKKNIGDILGSVYERDHVRAEIGGAKGDDLNNLVGNNLQAHLEYLEKAMRDAAADLDFEEAARLRDEIKRLRETELAL
LDDPMSRDAGVENTRDRRRQAAKGRGSAASPKGSPDRPLFRKPELDEMGSSGAHAVPAGQTLFRKNSLDEMTVRRTEKPV
GKTLPATPPDEDLIAPRRSKVGAGSYEDPADERQRKRRSRKTGRPGQ

Specific function: The UvrABC repair system catalyzes the recognition and processing of DNA lesions. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. Upon binding of the uvrA(2)B(2) complex to a putative damaged site, the DNA

COG id: COG0556

COG function: function code L; Helicase subunit of the DNA excision repair complex

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 UVR domain [H]

Homologues:

Organism=Escherichia coli, GI1786996, Length=668, Percent_Identity=60.4790419161677, Blast_Score=801, Evalue=0.0,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR014001
- InterPro:   IPR001650
- InterPro:   IPR014021
- InterPro:   IPR006935
- InterPro:   IPR001943
- InterPro:   IPR004807
- InterPro:   IPR009055 [H]

Pfam domain/function: PF00271 Helicase_C; PF04851 ResIII; PF02151 UVR [H]

EC number: NA

Molecular weight: Translated: 103109; Mature: 102977

Theoretical pI: Translated: 5.86; Mature: 5.86

Prosite motif: PS50151 UVR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
2.6 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
2.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MANSPRKNTGGFRESPQPPLSGTPLSASISDWAADIAREAEKPAKPRKKIPERSAAPGRT
CCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHCCCCHHHHCCCCCCCCCCC
GRGTSMGGAASARDRAAAGLMPIAGLDVTLEEAERIAPGGVTATVAALSNLIEGGDPNLK
CCCCCCCCCCCHHHHHHHCCCCCCCCCEEHHHHHHCCCCCHHHHHHHHHHHHCCCCCCCC
SAWVPHRPPRPEKSEGGIPFRMATEFKPSGDQPTAIRDLVEGISTSERTQVLLGVTGSGK
CCCCCCCCCCCCCCCCCCCEEEECCCCCCCCCCHHHHHHHHHCCCCCCCEEEEEECCCCC
TFTMAKVIEETQRPALILAPNKTLAAQLYGEFKSFFPDNAVEYFVSYYDYYQPEAYVPRS
EEHHHHHHHHHCCCEEEECCCHHHHHHHHHHHHHHCCCHHHHHHHHHHHHCCCCCCCCCC
DTYIEKESSINEQIDRMRHSATRALLERDDVIIVASVSCIYGIGSVETYTAMTFQMAVGD
CCCCCCHHHHHHHHHHHHHHHHHHHHCCCCEEEEEEHHHHHCCCCCHHHHHHEEEHHHCC
RLDQRQLLADLVEQQYKRRDADFTRGSFRVRGDTIEIFPAHLEDRAWRISLFGDEIEAIT
CCHHHHHHHHHHHHHHHHCCCCCCCCCEEEECCEEEEECCCCCCCEEEEEEECCHHHHHH
EFDPLTGKKTDDLKSVKIYANSHYVTPRPTLNQAIRQIKEELKLRLVELEKAGRLLEAQR
HCCCCCCCCCCCCCEEEEEECCEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LEQRTRFDLEMLEATGSCAGIENYSRYLTGRNPGEPPPTLFEYVPDNALVFVDESHVTVP
HHHHHHHHHHHHHHCCCCCCHHHHHHHHCCCCCCCCCCHHHHCCCCCEEEEEECCCCCHH
QIGAMYRGDFRRKATLAEYGFRLPSCMDNRPLRFEEWDAMRPLTVAVSATPGNWEMEQSG
HHHHHHHCCHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCEEEEEEECCCCCEECCCC
GVFAEQVIRPTGLIDPPVEIRPAKSQVDDVLGEIRETTKAGYRTLVTVLTKRMAEDLTEY
CHHHHHHHCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LHEQGIRVRYMHSDIDTLERIEIIRDLRLGAFDVLVGINLLREGLDIPECGLVAILDADK
HHHCCCEEEEECCCHHHHHHHHHHHHHHCCHHHHHHHHHHHHHCCCCCCCCEEEEEECCC
EGFLRSETSLVQTIGRAARNVDGRVILYADHITGSMERAIAETNRRREKQLEYNAGNGIT
CCCHHHHHHHHHHHHHHHHCCCCEEEEEECCCCCHHHHHHHHHHHHHHHHHCCCCCCCCC
PESIKKNIGDILGSVYERDHVRAEIGGAKGDDLNNLVGNNLQAHLEYLEKAMRDAAADLD
HHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHCCCHHHHHHHHHHHHHHHHCCCC
FEEAARLRDEIKRLRETELALLDDPMSRDAGVENTRDRRRQAAKGRGSAASPKGSPDRPL
HHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHCCCCCCCCCCCCCCCCC
FRKPELDEMGSSGAHAVPAGQTLFRKNSLDEMTVRRTEKPVGKTLPATPPDEDLIAPRRS
CCCCCHHHHCCCCCCCCCCCHHHHHCCCHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCC
KVGAGSYEDPADERQRKRRSRKTGRPGQ
CCCCCCCCCCHHHHHHHHHHHCCCCCCC
>Mature Secondary Structure 
ANSPRKNTGGFRESPQPPLSGTPLSASISDWAADIAREAEKPAKPRKKIPERSAAPGRT
CCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHCCCCHHHHCCCCCCCCCCC
GRGTSMGGAASARDRAAAGLMPIAGLDVTLEEAERIAPGGVTATVAALSNLIEGGDPNLK
CCCCCCCCCCCHHHHHHHCCCCCCCCCEEHHHHHHCCCCCHHHHHHHHHHHHCCCCCCCC
SAWVPHRPPRPEKSEGGIPFRMATEFKPSGDQPTAIRDLVEGISTSERTQVLLGVTGSGK
CCCCCCCCCCCCCCCCCCCEEEECCCCCCCCCCHHHHHHHHHCCCCCCCEEEEEECCCCC
TFTMAKVIEETQRPALILAPNKTLAAQLYGEFKSFFPDNAVEYFVSYYDYYQPEAYVPRS
EEHHHHHHHHHCCCEEEECCCHHHHHHHHHHHHHHCCCHHHHHHHHHHHHCCCCCCCCCC
DTYIEKESSINEQIDRMRHSATRALLERDDVIIVASVSCIYGIGSVETYTAMTFQMAVGD
CCCCCCHHHHHHHHHHHHHHHHHHHHCCCCEEEEEEHHHHHCCCCCHHHHHHEEEHHHCC
RLDQRQLLADLVEQQYKRRDADFTRGSFRVRGDTIEIFPAHLEDRAWRISLFGDEIEAIT
CCHHHHHHHHHHHHHHHHCCCCCCCCCEEEECCEEEEECCCCCCCEEEEEEECCHHHHHH
EFDPLTGKKTDDLKSVKIYANSHYVTPRPTLNQAIRQIKEELKLRLVELEKAGRLLEAQR
HCCCCCCCCCCCCCEEEEEECCEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LEQRTRFDLEMLEATGSCAGIENYSRYLTGRNPGEPPPTLFEYVPDNALVFVDESHVTVP
HHHHHHHHHHHHHHCCCCCCHHHHHHHHCCCCCCCCCCHHHHCCCCCEEEEEECCCCCHH
QIGAMYRGDFRRKATLAEYGFRLPSCMDNRPLRFEEWDAMRPLTVAVSATPGNWEMEQSG
HHHHHHHCCHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCEEEEEEECCCCCEECCCC
GVFAEQVIRPTGLIDPPVEIRPAKSQVDDVLGEIRETTKAGYRTLVTVLTKRMAEDLTEY
CHHHHHHHCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LHEQGIRVRYMHSDIDTLERIEIIRDLRLGAFDVLVGINLLREGLDIPECGLVAILDADK
HHHCCCEEEEECCCHHHHHHHHHHHHHHCCHHHHHHHHHHHHHCCCCCCCCEEEEEECCC
EGFLRSETSLVQTIGRAARNVDGRVILYADHITGSMERAIAETNRRREKQLEYNAGNGIT
CCCHHHHHHHHHHHHHHHHCCCCEEEEEECCCCCHHHHHHHHHHHHHHHHHCCCCCCCCC
PESIKKNIGDILGSVYERDHVRAEIGGAKGDDLNNLVGNNLQAHLEYLEKAMRDAAADLD
HHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHCCCHHHHHHHHHHHHHHHHCCCC
FEEAARLRDEIKRLRETELALLDDPMSRDAGVENTRDRRRQAAKGRGSAASPKGSPDRPL
HHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHCCCCCCCCCCCCCCCCC
FRKPELDEMGSSGAHAVPAGQTLFRKNSLDEMTVRRTEKPVGKTLPATPPDEDLIAPRRS
CCCCCHHHHCCCCCCCCCCCHHHHHCCCHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCC
KVGAGSYEDPADERQRKRRSRKTGRPGQ
CCCCCCCCCCHHHHHHHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: Hydrolase; Acting on ester bonds [C]

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 11214968 [H]