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The map label for this gene is btuB [H]

Identifier: 110634413

GI number: 110634413

Start: 2215869

End: 2217806

Strand: Direct

Name: btuB [H]

Synonym: Meso_2063

Alternate gene names: 110634413

Gene position: 2215869-2217806 (Clockwise)

Preceding gene: 110634408

Following gene: 110634414

Centisome position: 50.22

GC content: 61.15

Gene sequence:

>1938_bases
ATGATTAGACGACGCACTGCATCCAGCCTTACAGTTGGCGCATCCGCGCTTGCCACCCTTCTGGCGGGCTCCGCCGGCGC
TCAGGACATCGACCTGGGGGAAATCGTTGTAACGCCGAATCGCGCGCCCACGGCGCTGTCCGGGGCCGGTTCAACGGTTG
AAGTCATCGACGAGGACAGCATCGAGGCCCAGTCCCGCCCTCTGCTCACCGATTACCTGAACGAGTTGCCCGGCCTTTAT
GTCGCCACCCAGGGCGGCGTGGGCAAGGAAACCTCGCTGTCCATTCGCGGAGCGGACAAAAAATACATCAAGACCCTGTT
CAACGGCATCGATATCTCCGATCCATCCGCCACCCAGGTTCAGCCGTCCTTTGAGCATCTGCTGATCGGCGGCGTGAGCC
ATATCGAGGTGCTCAAGGGTTCGCAGAGCACGCTTTACGGCGCGGATGCCGTTGCCGGCGTCATCGACATATCCACGTTA
CGTAACGATCCCGTCGGCACCACCCACCGCGTGCTGGTCGAGGGCGGCTCGAACGAGACGGGGCGGGCAAGTTATGGCCT
GTCCAATGTCACGGAAACGGGCCGCATGTCCCTCGATATCGCCGGTCTCTACACGGGCGGCATCTCAGCCGCGCTGGTCA
ATGGCAACCCGCTGATCGACCCCGGCCAATCCAGCCTGGAGGATGATTTCTATCAGAACGTGACCGCGAGCTTTGCGGGC
GAGCAGCAAATGGGCGACAATGTCACCATTTTCGGCTCGGGCCTCCTCATCAACAGCAAGGGCGCCTTCGACGATTCGGG
CCTGCCGCCGACAGATAATGAGATGAACGAGGGACATTCCCGCCAGATGGCTGGCAGGGCCGGCATTTCCTTCGATCTGA
TGGAGGGCCGGTTCCGCAACACGGTTTCCGGTCAGCTGTCGGAAATCGACAGGGATATTTCGAGCGTCAGTATCTTTGGC
CCCTTCGAAGGCGAGTTCAACGGGCGCCGCGGCAAGCTCGATTATCAGGGCGCCTTTGATGTCAACGATCGCCTGACGCT
CCAGTTCGGCGCCGATTATGAGAGGCGGCAGGCGCATATCACCAATAATTACGGCACCGATACCCGTGATGCCGACTGGA
TCGCCGGTATCTGGGGGCAGGTGATCGCCGAGCCGATCGAAAATCTGACGGTCACCGCAGGCCTTCGCCACGACGATCAC
AGCCGCTTCGGCGGCTACACCACCTATCGCGGCGCGGTTGCGTATCTCTTCCCGTCGACGGGCACCAAGCTGCGCAGTTC
CATCGGCACGGGCTTTCGCGCCCCGAGCCTCTACGAGAACAACTATGTGAGCTACGATCCGACGGTTCCCCTCCCCGATC
TAGAGCCGGAGGAAAGCTTCTCCTGGGACGTCGGTATGGACCAAAGCTTCATGGGCGGGCGGGGAACGGCCAGCCTCACC
TATTTCCAGCTCGATACGGATAACCTCATCGATTACGATTTCATCAGGGATACCTACATCCAGTTCGAAGGCACGACGAG
GCGTCGCGGCGTCGAAATGGGCTTGGCCTATGAAGTCAACGACTGGCTCTCCCTTGGGGGGAACTACACCTACACCACCG
CGGTGGAAGCCGACGACGAGCGCCGGCCGCGCATCCCCCGGCATATGATCGGGCTCCTCGCCGAGGCCCGCCCCGCGGAG
AAGTGGACCGTATCCGCTTCTGCCAAGATCGCGCTTGATACGGTCGATTTCATATCGCCGAGCTTCGGCACCTATGAGCG
CGTGGAACTCGACGATTACGTGCTCCTGAACGCCAAGGTCGCCTACAAGCCCACGGAGGATACGGAGCTTTACCTGCGGG
TGGAAAACCTGCTCGACCAGGATTATCAGACCGTCTACGGCTACGGATCGCCCGGCATTTCGGCCTTCGCCGGGTTCAAG
GCGAAGTTCGGGCCGTGA

Upstream 100 bases:

>100_bases
CGGGGCTGTGGTTTCGCAGTGGTGGCGAACGATGTCATCGCTGGCGGGAACCAGGCAGACAGGCCGCTCCTCCAGCATCC
TTGGGGTATTGGGGGACGAT

Downstream 100 bases:

>100_bases
TGACAGCGGGTAAGAGGGGGGTGCGAAGAACGCTACGCAAGGCCACGATCTGCCTCATGACCTTGGCACTTTCATCCGCC
CCCGTGCTTGCCCAGGCACC

Product: TonB-dependent receptor

Products: NA

Alternate protein names: Cobalamin receptor; Outer membrane cobalamin translocator [H]

Number of amino acids: Translated: 645; Mature: 645

Protein sequence:

>645_residues
MIRRRTASSLTVGASALATLLAGSAGAQDIDLGEIVVTPNRAPTALSGAGSTVEVIDEDSIEAQSRPLLTDYLNELPGLY
VATQGGVGKETSLSIRGADKKYIKTLFNGIDISDPSATQVQPSFEHLLIGGVSHIEVLKGSQSTLYGADAVAGVIDISTL
RNDPVGTTHRVLVEGGSNETGRASYGLSNVTETGRMSLDIAGLYTGGISAALVNGNPLIDPGQSSLEDDFYQNVTASFAG
EQQMGDNVTIFGSGLLINSKGAFDDSGLPPTDNEMNEGHSRQMAGRAGISFDLMEGRFRNTVSGQLSEIDRDISSVSIFG
PFEGEFNGRRGKLDYQGAFDVNDRLTLQFGADYERRQAHITNNYGTDTRDADWIAGIWGQVIAEPIENLTVTAGLRHDDH
SRFGGYTTYRGAVAYLFPSTGTKLRSSIGTGFRAPSLYENNYVSYDPTVPLPDLEPEESFSWDVGMDQSFMGGRGTASLT
YFQLDTDNLIDYDFIRDTYIQFEGTTRRRGVEMGLAYEVNDWLSLGGNYTYTTAVEADDERRPRIPRHMIGLLAEARPAE
KWTVSASAKIALDTVDFISPSFGTYERVELDDYVLLNAKVAYKPTEDTELYLRVENLLDQDYQTVYGYGSPGISAFAGFK
AKFGP

Sequences:

>Translated_645_residues
MIRRRTASSLTVGASALATLLAGSAGAQDIDLGEIVVTPNRAPTALSGAGSTVEVIDEDSIEAQSRPLLTDYLNELPGLY
VATQGGVGKETSLSIRGADKKYIKTLFNGIDISDPSATQVQPSFEHLLIGGVSHIEVLKGSQSTLYGADAVAGVIDISTL
RNDPVGTTHRVLVEGGSNETGRASYGLSNVTETGRMSLDIAGLYTGGISAALVNGNPLIDPGQSSLEDDFYQNVTASFAG
EQQMGDNVTIFGSGLLINSKGAFDDSGLPPTDNEMNEGHSRQMAGRAGISFDLMEGRFRNTVSGQLSEIDRDISSVSIFG
PFEGEFNGRRGKLDYQGAFDVNDRLTLQFGADYERRQAHITNNYGTDTRDADWIAGIWGQVIAEPIENLTVTAGLRHDDH
SRFGGYTTYRGAVAYLFPSTGTKLRSSIGTGFRAPSLYENNYVSYDPTVPLPDLEPEESFSWDVGMDQSFMGGRGTASLT
YFQLDTDNLIDYDFIRDTYIQFEGTTRRRGVEMGLAYEVNDWLSLGGNYTYTTAVEADDERRPRIPRHMIGLLAEARPAE
KWTVSASAKIALDTVDFISPSFGTYERVELDDYVLLNAKVAYKPTEDTELYLRVENLLDQDYQTVYGYGSPGISAFAGFK
AKFGP
>Mature_645_residues
MIRRRTASSLTVGASALATLLAGSAGAQDIDLGEIVVTPNRAPTALSGAGSTVEVIDEDSIEAQSRPLLTDYLNELPGLY
VATQGGVGKETSLSIRGADKKYIKTLFNGIDISDPSATQVQPSFEHLLIGGVSHIEVLKGSQSTLYGADAVAGVIDISTL
RNDPVGTTHRVLVEGGSNETGRASYGLSNVTETGRMSLDIAGLYTGGISAALVNGNPLIDPGQSSLEDDFYQNVTASFAG
EQQMGDNVTIFGSGLLINSKGAFDDSGLPPTDNEMNEGHSRQMAGRAGISFDLMEGRFRNTVSGQLSEIDRDISSVSIFG
PFEGEFNGRRGKLDYQGAFDVNDRLTLQFGADYERRQAHITNNYGTDTRDADWIAGIWGQVIAEPIENLTVTAGLRHDDH
SRFGGYTTYRGAVAYLFPSTGTKLRSSIGTGFRAPSLYENNYVSYDPTVPLPDLEPEESFSWDVGMDQSFMGGRGTASLT
YFQLDTDNLIDYDFIRDTYIQFEGTTRRRGVEMGLAYEVNDWLSLGGNYTYTTAVEADDERRPRIPRHMIGLLAEARPAE
KWTVSASAKIALDTVDFISPSFGTYERVELDDYVLLNAKVAYKPTEDTELYLRVENLLDQDYQTVYGYGSPGISAFAGFK
AKFGP

Specific function: Involved in the active translocation of vitamin B12 (cyanocobalamin) across the outer membrane to the periplasmic space. It derives its energy for transport by interacting with the trans-periplasmic membrane protein TonB [H]

COG id: COG4206

COG function: function code H; Outer membrane cobalamin receptor protein

Gene ontology:

Cell location: Cell outer membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the TonB-dependent receptor family. BtuB (TC 1.B.14.3.1) subfamily [H]

Homologues:

Organism=Escherichia coli, GI1790405, Length=664, Percent_Identity=23.644578313253, Blast_Score=112, Evalue=9e-26,
Organism=Escherichia coli, GI1788478, Length=702, Percent_Identity=23.7891737891738, Blast_Score=103, Evalue=3e-23,

Paralogues:

None

Copy number: 100 Molecules/Cell In: Stationary Phase, Rich Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR012910
- InterPro:   IPR000531
- InterPro:   IPR010101
- InterPro:   IPR010917 [H]

Pfam domain/function: PF07715 Plug; PF00593 TonB_dep_Rec [H]

EC number: NA

Molecular weight: Translated: 69927; Mature: 69927

Theoretical pI: Translated: 4.32; Mature: 4.32

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
1.6 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
1.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIRRRTASSLTVGASALATLLAGSAGAQDIDLGEIVVTPNRAPTALSGAGSTVEVIDEDS
CCCCCCCCCEEECHHHHHHHHHCCCCCCCCCCCEEEECCCCCCCEECCCCCEEEEECCCC
IEAQSRPLLTDYLNELPGLYVATQGGVGKETSLSIRGADKKYIKTLFNGIDISDPSATQV
CCCCCCCCHHHHHHHCCCEEEEECCCCCCCCEEEEECCCHHHHHHHHCCCCCCCCCCCCC
QPSFEHLLIGGVSHIEVLKGSQSTLYGADAVAGVIDISTLRNDPVGTTHRVLVEGGSNET
CCCHHHEEECCCCEEEEECCCCCEEECCHHHHHEEEHHHHCCCCCCCEEEEEEECCCCCC
GRASYGLSNVTETGRMSLDIAGLYTGGISAALVNGNPLIDPGQSSLEDDFYQNVTASFAG
CCCCCCCCCCCCCCCEEEEEEEEEECCCEEEEECCCCCCCCCCHHHHHHHHHHHHHHHCC
EQQMGDNVTIFGSGLLINSKGAFDDSGLPPTDNEMNEGHSRQMAGRAGISFDLMEGRFRN
CHHCCCCEEEEECCEEEECCCCCCCCCCCCCCCCCCCCHHHHHHCCCCCEEEECCCCHHC
TVSGQLSEIDRDISSVSIFGPFEGEFNGRRGKLDYQGAFDVNDRLTLQFGADYERRQAHI
CCCHHHHHHHCCHHEEEEEECCCCCCCCCCCCEECCCEECCCCEEEEEECCCHHHHHEEE
TNNYGTDTRDADWIAGIWGQVIAEPIENLTVTAGLRHDDHSRFGGYTTYRGAVAYLFPST
ECCCCCCCCCCHHHHHHHHHHHHHHHHCEEEEEECCCCCCCCCCCEEEECCEEEEEECCC
GTKLRSSIGTGFRAPSLYENNYVSYDPTVPLPDLEPEESFSWDVGMDQSFMGGRGTASLT
CHHHHHHHCCCCCCCCCCCCCEEEECCCCCCCCCCCCCCCEECCCCCCCCCCCCCCCEEE
YFQLDTDNLIDYDFIRDTYIQFEGTTRRRGVEMGLAYEVNDWLSLGGNYTYTTAVEADDE
EEEECCCCCCCHHHHEEEEEEEECCCHHCCEEEEEEEECCHHHHCCCCEEEEEEECCCCC
RRPRIPRHMIGLLAEARPAEKWTVSASAKIALDTVDFISPSFGTYERVELDDYVLLNAKV
CCCCCHHHHHHHHHCCCCCCEEEEECCCEEEEEEHHHCCCCCCCEEEEECCCEEEEEEEE
AYKPTEDTELYLRVENLLDQDYQTVYGYGSPGISAFAGFKAKFGP
EECCCCCCEEEEEEHHHHCCCCCEEEECCCCCHHHHHCCCCCCCC
>Mature Secondary Structure
MIRRRTASSLTVGASALATLLAGSAGAQDIDLGEIVVTPNRAPTALSGAGSTVEVIDEDS
CCCCCCCCCEEECHHHHHHHHHCCCCCCCCCCCEEEECCCCCCCEECCCCCEEEEECCCC
IEAQSRPLLTDYLNELPGLYVATQGGVGKETSLSIRGADKKYIKTLFNGIDISDPSATQV
CCCCCCCCHHHHHHHCCCEEEEECCCCCCCCEEEEECCCHHHHHHHHCCCCCCCCCCCCC
QPSFEHLLIGGVSHIEVLKGSQSTLYGADAVAGVIDISTLRNDPVGTTHRVLVEGGSNET
CCCHHHEEECCCCEEEEECCCCCEEECCHHHHHEEEHHHHCCCCCCCEEEEEEECCCCCC
GRASYGLSNVTETGRMSLDIAGLYTGGISAALVNGNPLIDPGQSSLEDDFYQNVTASFAG
CCCCCCCCCCCCCCCEEEEEEEEEECCCEEEEECCCCCCCCCCHHHHHHHHHHHHHHHCC
EQQMGDNVTIFGSGLLINSKGAFDDSGLPPTDNEMNEGHSRQMAGRAGISFDLMEGRFRN
CHHCCCCEEEEECCEEEECCCCCCCCCCCCCCCCCCCCHHHHHHCCCCCEEEECCCCHHC
TVSGQLSEIDRDISSVSIFGPFEGEFNGRRGKLDYQGAFDVNDRLTLQFGADYERRQAHI
CCCHHHHHHHCCHHEEEEEECCCCCCCCCCCCEECCCEECCCCEEEEEECCCHHHHHEEE
TNNYGTDTRDADWIAGIWGQVIAEPIENLTVTAGLRHDDHSRFGGYTTYRGAVAYLFPST
ECCCCCCCCCCHHHHHHHHHHHHHHHHCEEEEEECCCCCCCCCCCEEEECCEEEEEECCC
GTKLRSSIGTGFRAPSLYENNYVSYDPTVPLPDLEPEESFSWDVGMDQSFMGGRGTASLT
CHHHHHHHCCCCCCCCCCCCCEEEECCCCCCCCCCCCCCCEECCCCCCCCCCCCCCCEEE
YFQLDTDNLIDYDFIRDTYIQFEGTTRRRGVEMGLAYEVNDWLSLGGNYTYTTAVEADDE
EEEECCCCCCCHHHHEEEEEEEECCCHHCCEEEEEEEECCHHHHCCCCEEEEEEECCCCC
RRPRIPRHMIGLLAEARPAEKWTVSASAKIALDTVDFISPSFGTYERVELDDYVLLNAKV
CCCCCHHHHHHHHHCCCCCCEEEEECCCEEEEEEHHHCCCCCCCEEEEECCCEEEEEEEE
AYKPTEDTELYLRVENLLDQDYQTVYGYGSPGISAFAGFKAKFGP
EECCCCCCEEEEEEHHHHCCCCCEEEECCCCCHHHHHCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: NA