Click here to switch to the map view.

The map label for this gene is fabH [H]

Identifier: 110634381

GI number: 110634381

Start: 2183352

End: 2184536

Strand: Reverse

Name: fabH [H]

Synonym: Meso_2031

Alternate gene names: 110634381

Gene position: 2184536-2183352 (Counterclockwise)

Preceding gene: 110634382

Following gene: 110634379

Centisome position: 49.51

GC content: 62.45

Gene sequence:

>1185_bases
ATGCTACGCCGGATTAGCGAGCGTGAGTCGGAAAATCCTGCACCAGACCGGGAGCGGGAAGGATTTGGCCGCGTCTGCCT
TTCCGGCCTCGGCGTCGAGATTCCGCGCGCAGTCATTTCCAACGAAGAACTCGTCGACAGCTTCAACCGATGGGTGGAAA
CACAAAATATCCGCAGGGCAGCGCTGGGCGAGGAGCCGCTGCCGCGTTCCGATGCGGATTTTATCGTCCAGGCGTCGGGC
ATCCGGCAGCGCCATGTTTATGAGCGGGAAGGCATTCTGGACCCGGCGCGGATGGCTCCGCGCATTCCGGCAAGGCGCGA
CGACGAGCTTTCCGTCATGGCCGAGTTCGGTCTCAAGGCCGCGCGGAAGGCGCTCGATCATGCGCGGCTCTCCCCGCGCG
ATATCGATCTCGTAATCTGCTCCGCCGCGCATCATCAGCGTCCCTATCCGGCCATCGCCATCGAAATCCAGCAGGCTTTG
GGCGCCGAAGGCGCTGCATTCGACATGGGCCTCGGCTGCTCCTCGGCACTTTTGGGCCTCCACACGGCAGCCAATCTGGT
GCGGACCGGCGCGCACCGCCGCGTGCTCGTGGTGACCCCGGAGCTGATCACGGCACATCTCGACTTCCGCGACCGACAGA
CGCATTTCATCTTCGGCGACGCAGCCACCGCCATGGTGGTGGAGGGTATGGATTCCGGCGGCAGCTATTCCGGCCGATTT
GAAGTGATCGATACGCGGCTCTGGACCCAGTTCTCAAGCAATATCCGCACGAATTTTGGGTTTCTCAGCCGCCTCGCCCA
GGACGATCCCTATAACCTCGCCGTCGAAGGCCAGCTCATCAAGCAGGCGGGCAGCAAGGTCTTCAAGGAGGTCACACTGG
CGGGGCACCAGTTCATCGTGGATTTCCTGGGCGAATATGGGCACACGCCGCTCACCATGCGCCGATTTTGGCTGCACCAG
GCGAATGCCCGCATGAACAAGATGATTCTCAAGCTCGCTTTCGGCGAGGAGGTGGGGCAGGACCGTGCGCCCACCGTTCT
TGAACGGCTCGGCAATACGGCGGCCGCGGGCGCCATCATCGCGCTCGCTGAAAATTACGAAGACATGCAGCCCGGCGAAT
TCGGCCTCCTCTGCGCCTTCGGCGCCGGCTATTCCATAGGCGGCGCGCTGTTAAGGATGATGTAA

Upstream 100 bases:

>100_bases
GCGCCGTCGCAAATAAACCTTATTCCATTCCCTTCCTCGGCAGTAAGCGGTATCCAACAGGATGGAGCCGAGTGCGGCTT
CGGTGCGAAGGGCATGGAAG

Downstream 100 bases:

>100_bases
GGGCTCCTGCGCGATGCCCTTGCGTGATGCGCACGCATTCAGGACCGAGGAAAGCTATTCGTCCTCCTCATCCGGCTCCA
GCAGCCTTGTCGCGCGCCAT

Product: 3-oxoacyl-(acyl carrier protein) synthase III

Products: NA

Alternate protein names: 3-oxoacyl-[acyl-carrier-protein] synthase III; Beta-ketoacyl-ACP synthase III; KAS III [H]

Number of amino acids: Translated: 394; Mature: 394

Protein sequence:

>394_residues
MLRRISERESENPAPDREREGFGRVCLSGLGVEIPRAVISNEELVDSFNRWVETQNIRRAALGEEPLPRSDADFIVQASG
IRQRHVYEREGILDPARMAPRIPARRDDELSVMAEFGLKAARKALDHARLSPRDIDLVICSAAHHQRPYPAIAIEIQQAL
GAEGAAFDMGLGCSSALLGLHTAANLVRTGAHRRVLVVTPELITAHLDFRDRQTHFIFGDAATAMVVEGMDSGGSYSGRF
EVIDTRLWTQFSSNIRTNFGFLSRLAQDDPYNLAVEGQLIKQAGSKVFKEVTLAGHQFIVDFLGEYGHTPLTMRRFWLHQ
ANARMNKMILKLAFGEEVGQDRAPTVLERLGNTAAAGAIIALAENYEDMQPGEFGLLCAFGAGYSIGGALLRMM

Sequences:

>Translated_394_residues
MLRRISERESENPAPDREREGFGRVCLSGLGVEIPRAVISNEELVDSFNRWVETQNIRRAALGEEPLPRSDADFIVQASG
IRQRHVYEREGILDPARMAPRIPARRDDELSVMAEFGLKAARKALDHARLSPRDIDLVICSAAHHQRPYPAIAIEIQQAL
GAEGAAFDMGLGCSSALLGLHTAANLVRTGAHRRVLVVTPELITAHLDFRDRQTHFIFGDAATAMVVEGMDSGGSYSGRF
EVIDTRLWTQFSSNIRTNFGFLSRLAQDDPYNLAVEGQLIKQAGSKVFKEVTLAGHQFIVDFLGEYGHTPLTMRRFWLHQ
ANARMNKMILKLAFGEEVGQDRAPTVLERLGNTAAAGAIIALAENYEDMQPGEFGLLCAFGAGYSIGGALLRMM
>Mature_394_residues
MLRRISERESENPAPDREREGFGRVCLSGLGVEIPRAVISNEELVDSFNRWVETQNIRRAALGEEPLPRSDADFIVQASG
IRQRHVYEREGILDPARMAPRIPARRDDELSVMAEFGLKAARKALDHARLSPRDIDLVICSAAHHQRPYPAIAIEIQQAL
GAEGAAFDMGLGCSSALLGLHTAANLVRTGAHRRVLVVTPELITAHLDFRDRQTHFIFGDAATAMVVEGMDSGGSYSGRF
EVIDTRLWTQFSSNIRTNFGFLSRLAQDDPYNLAVEGQLIKQAGSKVFKEVTLAGHQFIVDFLGEYGHTPLTMRRFWLHQ
ANARMNKMILKLAFGEEVGQDRAPTVLERLGNTAAAGAIIALAENYEDMQPGEFGLLCAFGAGYSIGGALLRMM

Specific function: Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the

COG id: COG0332

COG function: function code I; 3-oxoacyl-[acyl-carrier-protein] synthase III

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the fabH family [H]

Homologues:

Organism=Escherichia coli, GI1787333, Length=345, Percent_Identity=31.304347826087, Blast_Score=103, Evalue=1e-23,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013751
- InterPro:   IPR013747
- InterPro:   IPR004655
- InterPro:   IPR016039
- InterPro:   IPR016038 [H]

Pfam domain/function: PF08545 ACP_syn_III; PF08541 ACP_syn_III_C [H]

EC number: =2.3.1.180 [H]

Molecular weight: Translated: 43486; Mature: 43486

Theoretical pI: Translated: 6.44; Mature: 6.44

Prosite motif: PS00606 B_KETOACYL_SYNTHASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
4.1 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
3.0 %Met     (Mature Protein)
4.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLRRISERESENPAPDREREGFGRVCLSGLGVEIPRAVISNEELVDSFNRWVETQNIRRA
CCCCCCHHCCCCCCCCHHHCCHHHHHHHHCCCHHHHHHHCCHHHHHHHHHHHHHHHHHHH
ALGEEPLPRSDADFIVQASGIRQRHVYEREGILDPARMAPRIPARRDDELSVMAEFGLKA
HCCCCCCCCCCCCEEEEECCCHHHHHHHHCCCCCHHHHCCCCCCCCCCHHHHHHHHHHHH
ARKALDHARLSPRDIDLVICSAAHHQRPYPAIAIEIQQALGAEGAAFDMGLGCSSALLGL
HHHHHHHHCCCCCCEEEEEEECHHCCCCCCEEEEEEHHHHCCCCCEEECCCCHHHHHHHH
HTAANLVRTGAHRRVLVVTPELITAHLDFRDRQTHFIFGDAATAMVVEGMDSGGSYSGRF
HHHHHHHHCCCCCEEEEECHHHHEEECCCCCCCEEEEECCCHHHHEEECCCCCCCCCCEE
EVIDTRLWTQFSSNIRTNFGFLSRLAQDDPYNLAVEGQLIKQAGSKVFKEVTLAGHQFIV
EEEHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEECHHHHHHHHHHHHHHHHHHHHHHHH
DFLGEYGHTPLTMRRFWLHQANARMNKMILKLAFGEEVGQDRAPTVLERLGNTAAAGAII
HHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHCHHCCCCCCCHHHHHCCCHHHHHHHE
ALAENYEDMQPGEFGLLCAFGAGYSIGGALLRMM
EEECCCCCCCCCCEEEEEEECCCCHHHHHHHHCC
>Mature Secondary Structure
MLRRISERESENPAPDREREGFGRVCLSGLGVEIPRAVISNEELVDSFNRWVETQNIRRA
CCCCCCHHCCCCCCCCHHHCCHHHHHHHHCCCHHHHHHHCCHHHHHHHHHHHHHHHHHHH
ALGEEPLPRSDADFIVQASGIRQRHVYEREGILDPARMAPRIPARRDDELSVMAEFGLKA
HCCCCCCCCCCCCEEEEECCCHHHHHHHHCCCCCHHHHCCCCCCCCCCHHHHHHHHHHHH
ARKALDHARLSPRDIDLVICSAAHHQRPYPAIAIEIQQALGAEGAAFDMGLGCSSALLGL
HHHHHHHHCCCCCCEEEEEEECHHCCCCCCEEEEEEHHHHCCCCCEEECCCCHHHHHHHH
HTAANLVRTGAHRRVLVVTPELITAHLDFRDRQTHFIFGDAATAMVVEGMDSGGSYSGRF
HHHHHHHHCCCCCEEEEECHHHHEEECCCCCCCEEEEECCCHHHHEEECCCCCCCCCCEE
EVIDTRLWTQFSSNIRTNFGFLSRLAQDDPYNLAVEGQLIKQAGSKVFKEVTLAGHQFIV
EEEHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEECHHHHHHHHHHHHHHHHHHHHHHHH
DFLGEYGHTPLTMRRFWLHQANARMNKMILKLAFGEEVGQDRAPTVLERLGNTAAAGAII
HHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHCHHCCCCCCCHHHHHCCCHHHHHHHE
ALAENYEDMQPGEFGLLCAFGAGYSIGGALLRMM
EEECCCCCCCCCCEEEEEEECCCCHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA