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The map label for this gene is phbC [H]

Identifier: 110634275

GI number: 110634275

Start: 2059494

End: 2061317

Strand: Direct

Name: phbC [H]

Synonym: Meso_1925

Alternate gene names: 110634275

Gene position: 2059494-2061317 (Clockwise)

Preceding gene: 110634268

Following gene: 110634276

Centisome position: 46.67

GC content: 60.96

Gene sequence:

>1824_bases
ATGGCCAGCGGGGAAAATAAGGACGACCGCGAAACGCCCGACCCGACCGAAGCCTACACCGTTCGGAATCCGGAGCGCTT
CGCTCTCAACCTCGCCCGAGCCGTGGAAGAAGCCGGCAAGGCGGCCGCCGTTTGGGTTCGCGCCCGCGAAGCGGGCAAAA
GCACGACCGGCATGCCGCAGCCCTATCAGGAAGCGGTTCGCACCCTCTCGAAGCTGACGGAATATTGGCTTTCGGATCCC
GCGCGCGCCGTCGAGGCGCAGACGAAGCTCCTTTCCGCCTACATGACGGTTTGGGTCAACTCGATCAGAAGGCTGAGCGG
CGAGACGATTGATGCCGTGGAGCCGGAGCCCGGCGACCGGCGCTTCGAAGATCCGGAATGGGCACAAAACGCGTTTTTCG
ATTTCTTGAAGCAGGTCTATCTGGTGACCGCGCGCTGGGCGGCCGATCTTGTGGAAAACGCAGAAGGACTGGACGAGACG
GCCCGGCAGAGGGCCCGCTTCTACGTGACACAGCTGAGCGAAGCGCTCTCTCCCACGAATTTTGTCCTCACAAACCCGCA
GCTCCTGCGCGAAACCTTCGAGTCGGACGGCGACAATCTCGTGCGTGGCATGCGGATGCTGGTCGAGGACGTGATGGCCG
GCAAAGGCGAGATCCGGCTGCGCCAGACCGACCGCAGCAAGTTCGAGCTTGGCAAGAACGTTGCGGCCACGCCAGGCAAG
GTTGTGGCGCGCAACGAACTCGCGGAGATCATCCAGTACGAGCCGTCGACCGAAACGGTGCTACGGCGGCCGTTGATGAT
CGTTCCCCCCTGGATCAACAAATTCTATGTGCTCGATCTTAAACCGGAGCGGTCGTTCATTCGCTGGGCCGTCGCACAGG
GCCATACCGTTTTCGTGATCTCCTGGGTAAACCCTGACGAGCGGCACGCGACCTATGGCTGGGACGAATATGTGAGCTTG
GGGATCGAGTTCGCACTGGAGACGATTGCCCGGCAGACCGGGGAAAAGGCGATCAATGCGGTCGGTTATTGCGTCGGCGG
CACCCTCCTCGCAGCATCGCTGGCGCTCATGGCTCAGCAAAAGGATGATCGCATAGCCACCGCCACATTCTTCGCCAGCC
AGGTGGATTTCACCTTTGCGGGCGACCTGAAAGTCTTTGTCGACGAGGAACAGGTCGCGGCGCTGGAACAGGCGATGGAG
GAACGGGGCTTTCTCGAAGCCAACCGTATGGCGAGCGCCTTCAACATGCTGCGCGCCCGCGATCTCATCTGGCCTTACGT
GGTCAACAATTATCTGCGCGGGCGAGAGCCGCTTCCCTTCGACCTGCTTTATTGGAACGCCGATTCCACCAGGATGACAG
CGGCCAACCACTCCTATTACCTGCGCAATTGCTATCTGGAGAACAATCTGGCGAAGGGGTTGGCCACACTGGGCGGGCGC
CGATTGTCTCTCGCGGATATCAAGATCCCGGTCTTTAGCCTCGCTGCTGCCGAGGATCATATCGCTCCGGCAAAATCCGT
CCTGTTCGGCAGCCGGCTTTTTGGCGGGCCGGTGGAATTCGTGCTTGCCGGTTCCGGCCACATAGCCGGCGTGGTCAATC
CGCCCGAACCCGGCAAATACCGGCATTGGACAGGGCAAGCCGCCCTTGCCGGGAGCCTCGAAGAATGGATGAGCAAAGCC
CAGGAGCACCCTGGTTCATGGTGGCCGCATTGGCACGCCTGGATCGAAAAGAACTCACATGAACGGGTGAAAGCGCGCAA
GCTCGACCGGCGAAGGAAATGGCTCGCAGACGCACCGGGCGAATATGTAAAGATGGCCGTCTAA

Upstream 100 bases:

>100_bases
AATGTCGTATGCGGGCCATGATTTTCATATGTTCCCGTGAACATGGACAAGGTTTGAATCAGCGCTATCATAGCGCCCTT
CGGGAGGTCCAGCATCAAGA

Downstream 100 bases:

>100_bases
TAGTTGCAACAGACTGGAACATTATTTGAAGACGGCTAGGCGGCGGGCATGGGCCCGTTTCAGCTTAAGTATATTGCTAT
AAAGGGATAATTTGGCTACC

Product: poly(R)-hydroxyalkanoic acid synthase, class I

Products: NA

Alternate protein names: PHA synthase; PHB synthase; Poly(3-hydroxyalkanoate) polymerase; PHA polymerase; Poly(3-hydroxybutyrate) polymerase; PHB polymerase; Polyhydroxyalkanoic acid synthase [H]

Number of amino acids: Translated: 607; Mature: 606

Protein sequence:

>607_residues
MASGENKDDRETPDPTEAYTVRNPERFALNLARAVEEAGKAAAVWVRAREAGKSTTGMPQPYQEAVRTLSKLTEYWLSDP
ARAVEAQTKLLSAYMTVWVNSIRRLSGETIDAVEPEPGDRRFEDPEWAQNAFFDFLKQVYLVTARWAADLVENAEGLDET
ARQRARFYVTQLSEALSPTNFVLTNPQLLRETFESDGDNLVRGMRMLVEDVMAGKGEIRLRQTDRSKFELGKNVAATPGK
VVARNELAEIIQYEPSTETVLRRPLMIVPPWINKFYVLDLKPERSFIRWAVAQGHTVFVISWVNPDERHATYGWDEYVSL
GIEFALETIARQTGEKAINAVGYCVGGTLLAASLALMAQQKDDRIATATFFASQVDFTFAGDLKVFVDEEQVAALEQAME
ERGFLEANRMASAFNMLRARDLIWPYVVNNYLRGREPLPFDLLYWNADSTRMTAANHSYYLRNCYLENNLAKGLATLGGR
RLSLADIKIPVFSLAAAEDHIAPAKSVLFGSRLFGGPVEFVLAGSGHIAGVVNPPEPGKYRHWTGQAALAGSLEEWMSKA
QEHPGSWWPHWHAWIEKNSHERVKARKLDRRRKWLADAPGEYVKMAV

Sequences:

>Translated_607_residues
MASGENKDDRETPDPTEAYTVRNPERFALNLARAVEEAGKAAAVWVRAREAGKSTTGMPQPYQEAVRTLSKLTEYWLSDP
ARAVEAQTKLLSAYMTVWVNSIRRLSGETIDAVEPEPGDRRFEDPEWAQNAFFDFLKQVYLVTARWAADLVENAEGLDET
ARQRARFYVTQLSEALSPTNFVLTNPQLLRETFESDGDNLVRGMRMLVEDVMAGKGEIRLRQTDRSKFELGKNVAATPGK
VVARNELAEIIQYEPSTETVLRRPLMIVPPWINKFYVLDLKPERSFIRWAVAQGHTVFVISWVNPDERHATYGWDEYVSL
GIEFALETIARQTGEKAINAVGYCVGGTLLAASLALMAQQKDDRIATATFFASQVDFTFAGDLKVFVDEEQVAALEQAME
ERGFLEANRMASAFNMLRARDLIWPYVVNNYLRGREPLPFDLLYWNADSTRMTAANHSYYLRNCYLENNLAKGLATLGGR
RLSLADIKIPVFSLAAAEDHIAPAKSVLFGSRLFGGPVEFVLAGSGHIAGVVNPPEPGKYRHWTGQAALAGSLEEWMSKA
QEHPGSWWPHWHAWIEKNSHERVKARKLDRRRKWLADAPGEYVKMAV
>Mature_606_residues
ASGENKDDRETPDPTEAYTVRNPERFALNLARAVEEAGKAAAVWVRAREAGKSTTGMPQPYQEAVRTLSKLTEYWLSDPA
RAVEAQTKLLSAYMTVWVNSIRRLSGETIDAVEPEPGDRRFEDPEWAQNAFFDFLKQVYLVTARWAADLVENAEGLDETA
RQRARFYVTQLSEALSPTNFVLTNPQLLRETFESDGDNLVRGMRMLVEDVMAGKGEIRLRQTDRSKFELGKNVAATPGKV
VARNELAEIIQYEPSTETVLRRPLMIVPPWINKFYVLDLKPERSFIRWAVAQGHTVFVISWVNPDERHATYGWDEYVSLG
IEFALETIARQTGEKAINAVGYCVGGTLLAASLALMAQQKDDRIATATFFASQVDFTFAGDLKVFVDEEQVAALEQAMEE
RGFLEANRMASAFNMLRARDLIWPYVVNNYLRGREPLPFDLLYWNADSTRMTAANHSYYLRNCYLENNLAKGLATLGGRR
LSLADIKIPVFSLAAAEDHIAPAKSVLFGSRLFGGPVEFVLAGSGHIAGVVNPPEPGKYRHWTGQAALAGSLEEWMSKAQ
EHPGSWWPHWHAWIEKNSHERVKARKLDRRRKWLADAPGEYVKMAV

Specific function: Polymerizes d(-)-3-hydroxybutyryl-CoA to create PHB which consists of thousands of hydroxybutyrate molecules linked end to end. PHB serves as an intracellular energy reserve material when cells grow under conditions of nutrient limitation [H]

COG id: COG3243

COG function: function code I; Poly(3-hydroxyalkanoate) synthetase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the PHA/PHB synthase family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000073
- InterPro:   IPR010963
- InterPro:   IPR010941 [H]

Pfam domain/function: PF00561 Abhydrolase_1; PF07167 PhaC_N [H]

EC number: NA

Molecular weight: Translated: 68383; Mature: 68252

Theoretical pI: Translated: 6.07; Mature: 6.07

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
2.6 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
2.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MASGENKDDRETPDPTEAYTVRNPERFALNLARAVEEAGKAAAVWVRAREAGKSTTGMPQ
CCCCCCCCCCCCCCCCCEEECCCHHHHHHHHHHHHHHHCCEEEEEEEEHHCCCCCCCCCC
PYQEAVRTLSKLTEYWLSDPARAVEAQTKLLSAYMTVWVNSIRRLSGETIDAVEPEPGDR
HHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCC
RFEDPEWAQNAFFDFLKQVYLVTARWAADLVENAEGLDETARQRARFYVTQLSEALSPTN
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHCCCCC
FVLTNPQLLRETFESDGDNLVRGMRMLVEDVMAGKGEIRLRQTDRSKFELGKNVAATPGK
EEECCHHHHHHHHHCCCHHHHHHHHHHHHHHHCCCCCEEEEECCCHHHHHCCCCCCCCCC
VVARNELAEIIQYEPSTETVLRRPLMIVPPWINKFYVLDLKPERSFIRWAVAQGHTVFVI
HHHHHHHHHHHHCCCCHHHHHHCCCEEECCCCCCEEEEEECCCHHHHHHHEECCCEEEEE
SWVNPDERHATYGWDEYVSLGIEFALETIARQTGEKAINAVGYCVGGTLLAASLALMAQQ
EECCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHC
KDDRIATATFFASQVDFTFAGDLKVFVDEEQVAALEQAMEERGFLEANRMASAFNMLRAR
CCCCEEHHHHHHHHCCEEEECCEEEEECHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHH
DLIWPYVVNNYLRGREPLPFDLLYWNADSTRMTAANHSYYLRNCYLENNLAKGLATLGGR
HHHHHHHHHHHHCCCCCCCEEEEEECCCCCEEEECCCCEEEEHEEEHHHHHHHHHHHCCC
RLSLADIKIPVFSLAAAEDHIAPAKSVLFGSRLFGGPVEFVLAGSGHIAGVVNPPEPGKY
EEEEEEEECCHHEEHHCHHCCCHHHHHHHHHHHCCCCEEEEEECCCCEEEECCCCCCCCC
RHWTGQAALAGSLEEWMSKAQEHPGSWWPHWHAWIEKNSHERVKARKLDRRRKWLADAPG
CCCCCCHHHHHHHHHHHHHHHHCCCCCCCCHHHHHCCCCHHHHHHHHHHHHHHHHHCCCC
EYVKMAV
CCEEECC
>Mature Secondary Structure 
ASGENKDDRETPDPTEAYTVRNPERFALNLARAVEEAGKAAAVWVRAREAGKSTTGMPQ
CCCCCCCCCCCCCCCCEEECCCHHHHHHHHHHHHHHHCCEEEEEEEEHHCCCCCCCCCC
PYQEAVRTLSKLTEYWLSDPARAVEAQTKLLSAYMTVWVNSIRRLSGETIDAVEPEPGDR
HHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCC
RFEDPEWAQNAFFDFLKQVYLVTARWAADLVENAEGLDETARQRARFYVTQLSEALSPTN
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHCCCCC
FVLTNPQLLRETFESDGDNLVRGMRMLVEDVMAGKGEIRLRQTDRSKFELGKNVAATPGK
EEECCHHHHHHHHHCCCHHHHHHHHHHHHHHHCCCCCEEEEECCCHHHHHCCCCCCCCCC
VVARNELAEIIQYEPSTETVLRRPLMIVPPWINKFYVLDLKPERSFIRWAVAQGHTVFVI
HHHHHHHHHHHHCCCCHHHHHHCCCEEECCCCCCEEEEEECCCHHHHHHHEECCCEEEEE
SWVNPDERHATYGWDEYVSLGIEFALETIARQTGEKAINAVGYCVGGTLLAASLALMAQQ
EECCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHC
KDDRIATATFFASQVDFTFAGDLKVFVDEEQVAALEQAMEERGFLEANRMASAFNMLRAR
CCCCEEHHHHHHHHCCEEEECCEEEEECHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHH
DLIWPYVVNNYLRGREPLPFDLLYWNADSTRMTAANHSYYLRNCYLENNLAKGLATLGGR
HHHHHHHHHHHHCCCCCCCEEEEEECCCCCEEEECCCCEEEEHEEEHHHHHHHHHHHCCC
RLSLADIKIPVFSLAAAEDHIAPAKSVLFGSRLFGGPVEFVLAGSGHIAGVVNPPEPGKY
EEEEEEEECCHHEEHHCHHCCCHHHHHHHHHHHCCCCEEEEEECCCCEEEECCCCCCCCC
RHWTGQAALAGSLEEWMSKAQEHPGSWWPHWHAWIEKNSHERVKARKLDRRRKWLADAPG
CCCCCCHHHHHHHHHHHHHHHHCCCCCCCCHHHHHCCCCHHHHHHHHHHHHHHHHHCCCC
EYVKMAV
CCEEECC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 7582015; 9734305; 11481430 [H]