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The map label for this gene is aatC [H]

Identifier: 110634273

GI number: 110634273

Start: 2057793

End: 2059010

Strand: Reverse

Name: aatC [H]

Synonym: Meso_1923

Alternate gene names: 110634273

Gene position: 2059010-2057793 (Counterclockwise)

Preceding gene: 110634274

Following gene: 110634272

Centisome position: 46.66

GC content: 61.82

Gene sequence:

>1218_bases
ATGGAAGAGTTTCACAAGGTCCGCCGGCTTCCGCCATATGTGTTCGAGCAGGTCAACAGGCTCAAGGCCTCAGCCCGCTC
GCGCGGCGCCGATATTATCGATCTAGGCATGGGGAACCCGGACCTGCCGACGCCCAAGGCGATCGTGGACAAGCTCTGCG
AGGTGGTGCGTGATCCGCGCACGCATCGATATTCGTCTTCGCGCGGCATTCCGGGCCTTCGGCGCGCTCAGGCTGCGTAT
TATGCCCGCCGCTTCGGCGTGAAGCTCAATCCAGATACGCAGGTCGTCGCCACGCTCGGCTCCAAGGAGGGCTTCGCCAA
CATGGCCCAGGCGATCACCGCGCCGGGCGACGTGGTGCTTTGCCCCAATCCGACCTATCCGATCCACGCTTTCGGTTTCA
TCATGTCGGGTGGAGTGATCCGCTCGATTCCCGCGGAGCCGGACCATAATTTCATTCCGGTGCTGGAGCGGGCGGTACGG
CATTCGATCCCCAAGCCACTGGCGCTCATCCTGAACTATCCGTCCAATCCGACGGCTTGCCTGGCCAGTCTTGATTTTTA
CAAGGATGTCGTGGCCTTCGCGCGCAAGCACGACATCATCATCCTTTCCGATCTCGCCTATGCCGAGATTTATTTCGATA
CCGAAGCGCCACCTTCTGTCTTGCAGGTGCCGGGGGCGATGGATGTGGCGGTCGAATTCACATCCATGTCGAAAACCTTC
TCCATGCCAGGGTGGCGCATGGGCTTTGCGGTGGGCAACGAGCGGCTGATCGCTGCGCTTTCCCGCGTGAAGTCCTATCT
CGACTATGGCGCTTTCACCCCCATCCAGGTGGCTGCCACCGCCGCCCTTAATTCCGACGGCACGGAAATCGAGGAAGTTC
GCTCCGTCTATCACCGCCGGCGTGACGTAATGGTGGATGCATTTGGCCGTGCCGGCTGGCAGGTGCCGCCGCCGCCAGCC
ACCATGTTTGCCTGGGCTCCAATACCGGAGCCGTTTCGCCAGCTTGGCTCGCTTGAGTTCTCCAAGCTCCTGGTCGAAAA
GGCCGATGTGGCGGTCGCGCCTGGAATCGGCTTCGGCGAGCATGGCGACGATTACGTGCGCATTGCGCTTGTGGAGAACG
AGCACCGTATCCGCCAGGCGGCGCGCAACATCAAGCGCTTCCTTGCCACGGCGGCGGAGCACCCCAGCAACGTCGTCCCG
TTTGCGGCTACCCGCTAA

Upstream 100 bases:

>100_bases
GAGCCAGATCGAGTCTCCCGCTGATCGGTGAGTTCAAGAAGCTATCGACCGTTCTGGCGAACGGGTGTATAGGGCGCAAT
CAGCAATCCGGAACATCGCC

Downstream 100 bases:

>100_bases
GCGGCTGCAAAATCATAATAGTTGAAGGAAGGCATTAAACATGGCCGACGCCTTGCGCATAGGAATTGCGGGTCTTGGTA
CCGTTGGCGCGAGCGTTGTC

Product: aminotransferase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 405; Mature: 405

Protein sequence:

>405_residues
MEEFHKVRRLPPYVFEQVNRLKASARSRGADIIDLGMGNPDLPTPKAIVDKLCEVVRDPRTHRYSSSRGIPGLRRAQAAY
YARRFGVKLNPDTQVVATLGSKEGFANMAQAITAPGDVVLCPNPTYPIHAFGFIMSGGVIRSIPAEPDHNFIPVLERAVR
HSIPKPLALILNYPSNPTACLASLDFYKDVVAFARKHDIIILSDLAYAEIYFDTEAPPSVLQVPGAMDVAVEFTSMSKTF
SMPGWRMGFAVGNERLIAALSRVKSYLDYGAFTPIQVAATAALNSDGTEIEEVRSVYHRRRDVMVDAFGRAGWQVPPPPA
TMFAWAPIPEPFRQLGSLEFSKLLVEKADVAVAPGIGFGEHGDDYVRIALVENEHRIRQAARNIKRFLATAAEHPSNVVP
FAATR

Sequences:

>Translated_405_residues
MEEFHKVRRLPPYVFEQVNRLKASARSRGADIIDLGMGNPDLPTPKAIVDKLCEVVRDPRTHRYSSSRGIPGLRRAQAAY
YARRFGVKLNPDTQVVATLGSKEGFANMAQAITAPGDVVLCPNPTYPIHAFGFIMSGGVIRSIPAEPDHNFIPVLERAVR
HSIPKPLALILNYPSNPTACLASLDFYKDVVAFARKHDIIILSDLAYAEIYFDTEAPPSVLQVPGAMDVAVEFTSMSKTF
SMPGWRMGFAVGNERLIAALSRVKSYLDYGAFTPIQVAATAALNSDGTEIEEVRSVYHRRRDVMVDAFGRAGWQVPPPPA
TMFAWAPIPEPFRQLGSLEFSKLLVEKADVAVAPGIGFGEHGDDYVRIALVENEHRIRQAARNIKRFLATAAEHPSNVVP
FAATR
>Mature_405_residues
MEEFHKVRRLPPYVFEQVNRLKASARSRGADIIDLGMGNPDLPTPKAIVDKLCEVVRDPRTHRYSSSRGIPGLRRAQAAY
YARRFGVKLNPDTQVVATLGSKEGFANMAQAITAPGDVVLCPNPTYPIHAFGFIMSGGVIRSIPAEPDHNFIPVLERAVR
HSIPKPLALILNYPSNPTACLASLDFYKDVVAFARKHDIIILSDLAYAEIYFDTEAPPSVLQVPGAMDVAVEFTSMSKTF
SMPGWRMGFAVGNERLIAALSRVKSYLDYGAFTPIQVAATAALNSDGTEIEEVRSVYHRRRDVMVDAFGRAGWQVPPPPA
TMFAWAPIPEPFRQLGSLEFSKLLVEKADVAVAPGIGFGEHGDDYVRIALVENEHRIRQAARNIKRFLATAAEHPSNVVP
FAATR

Specific function: Unknown

COG id: COG0436

COG function: function code E; Aspartate/tyrosine/aromatic aminotransferase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family [H]

Homologues:

Organism=Homo sapiens, GI95147551, Length=391, Percent_Identity=23.0179028132992, Blast_Score=111, Evalue=1e-24,
Organism=Homo sapiens, GI169881279, Length=391, Percent_Identity=23.0179028132992, Blast_Score=111, Evalue=1e-24,
Organism=Homo sapiens, GI56713256, Length=391, Percent_Identity=21.7391304347826, Blast_Score=100, Evalue=3e-21,
Organism=Homo sapiens, GI56713254, Length=391, Percent_Identity=21.7391304347826, Blast_Score=100, Evalue=3e-21,
Organism=Homo sapiens, GI169881281, Length=242, Percent_Identity=22.3140495867769, Blast_Score=75, Evalue=1e-13,
Organism=Escherichia coli, GI1788722, Length=382, Percent_Identity=52.8795811518325, Blast_Score=433, Evalue=1e-122,
Organism=Escherichia coli, GI1786816, Length=386, Percent_Identity=25.9067357512953, Blast_Score=139, Evalue=3e-34,
Organism=Escherichia coli, GI1788627, Length=242, Percent_Identity=26.8595041322314, Blast_Score=90, Evalue=2e-19,
Organism=Caenorhabditis elegans, GI17567369, Length=393, Percent_Identity=22.1374045801527, Blast_Score=112, Evalue=3e-25,
Organism=Caenorhabditis elegans, GI71994476, Length=267, Percent_Identity=26.9662921348315, Blast_Score=101, Evalue=9e-22,
Organism=Caenorhabditis elegans, GI71994472, Length=267, Percent_Identity=26.9662921348315, Blast_Score=101, Evalue=9e-22,
Organism=Saccharomyces cerevisiae, GI6322401, Length=389, Percent_Identity=21.3367609254499, Blast_Score=94, Evalue=3e-20,
Organism=Drosophila melanogaster, GI28573069, Length=389, Percent_Identity=23.9074550128535, Blast_Score=113, Evalue=2e-25,
Organism=Drosophila melanogaster, GI24646114, Length=389, Percent_Identity=23.9074550128535, Blast_Score=113, Evalue=2e-25,
Organism=Drosophila melanogaster, GI28573067, Length=389, Percent_Identity=23.9074550128535, Blast_Score=113, Evalue=2e-25,
Organism=Drosophila melanogaster, GI28573065, Length=389, Percent_Identity=23.9074550128535, Blast_Score=113, Evalue=2e-25,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004839
- InterPro:   IPR004838
- InterPro:   IPR015424
- InterPro:   IPR015421
- InterPro:   IPR015422 [H]

Pfam domain/function: PF00155 Aminotran_1_2 [H]

EC number: 2.6.1.- [C]

Molecular weight: Translated: 44596; Mature: 44596

Theoretical pI: Translated: 8.97; Mature: 8.97

Prosite motif: PS00105 AA_TRANSFER_CLASS_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MEEFHKVRRLPPYVFEQVNRLKASARSRGADIIDLGMGNPDLPTPKAIVDKLCEVVRDPR
CCHHHHHHCCCHHHHHHHHHHHHHHHHCCCCEEEECCCCCCCCCHHHHHHHHHHHHCCCC
THRYSSSRGIPGLRRAQAAYYARRFGVKLNPDTQVVATLGSKEGFANMAQAITAPGDVVL
CCCCCCCCCCCHHHHHHHHHHHHHCCCEECCCCEEEEECCCCCHHHHHHHHHCCCCCEEE
CPNPTYPIHAFGFIMSGGVIRSIPAEPDHNFIPVLERAVRHSIPKPLALILNYPSNPTAC
CCCCCCCHHHHHHHHCCCEEEECCCCCCCCHHHHHHHHHHHCCCCCEEEEEECCCCCHHH
LASLDFYKDVVAFARKHDIIILSDLAYAEIYFDTEAPPSVLQVPGAMDVAVEFTSMSKTF
HHHHHHHHHHHHHHHCCCEEEEECCCEEEEEECCCCCHHHEECCCCCEEEEEEHHHHHHH
SMPGWRMGFAVGNERLIAALSRVKSYLDYGAFTPIQVAATAALNSDGTEIEEVRSVYHRR
CCCCCEEEEEECCHHHHHHHHHHHHHHHHCCCCHHHHHHHHHCCCCCCHHHHHHHHHHHH
RDVMVDAFGRAGWQVPPPPATMFAWAPIPEPFRQLGSLEFSKLLVEKADVAVAPGIGFGE
HHHHHHHHCCCCCCCCCCCCCEEEECCCCHHHHHHCCHHHHHHHHHHCCEEEECCCCCCC
HGDDYVRIALVENEHRIRQAARNIKRFLATAAEHPSNVVPFAATR
CCCCEEEEEEECCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCC
>Mature Secondary Structure
MEEFHKVRRLPPYVFEQVNRLKASARSRGADIIDLGMGNPDLPTPKAIVDKLCEVVRDPR
CCHHHHHHCCCHHHHHHHHHHHHHHHHCCCCEEEECCCCCCCCCHHHHHHHHHHHHCCCC
THRYSSSRGIPGLRRAQAAYYARRFGVKLNPDTQVVATLGSKEGFANMAQAITAPGDVVL
CCCCCCCCCCCHHHHHHHHHHHHHCCCEECCCCEEEEECCCCCHHHHHHHHHCCCCCEEE
CPNPTYPIHAFGFIMSGGVIRSIPAEPDHNFIPVLERAVRHSIPKPLALILNYPSNPTAC
CCCCCCCHHHHHHHHCCCEEEECCCCCCCCHHHHHHHHHHHCCCCCEEEEEECCCCCHHH
LASLDFYKDVVAFARKHDIIILSDLAYAEIYFDTEAPPSVLQVPGAMDVAVEFTSMSKTF
HHHHHHHHHHHHHHHCCCEEEEECCCEEEEEECCCCCHHHEECCCCCEEEEEEHHHHHHH
SMPGWRMGFAVGNERLIAALSRVKSYLDYGAFTPIQVAATAALNSDGTEIEEVRSVYHRR
CCCCCEEEEEECCHHHHHHHHHHHHHHHHCCCCHHHHHHHHHCCCCCCHHHHHHHHHHHH
RDVMVDAFGRAGWQVPPPPATMFAWAPIPEPFRQLGSLEFSKLLVEKADVAVAPGIGFGE
HHHHHHHHCCCCCCCCCCCCCEEEECCCCHHHHHHCCHHHHHHHHHHCCEEEECCCCCCC
HGDDYVRIALVENEHRIRQAARNIKRFLATAAEHPSNVVPFAATR
CCCCEEEEEEECCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: Pyridoxal Phosphate. [C]

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 11481430; 9734305 [H]