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The map label for this gene is glpD [H]

Identifier: 110634211

GI number: 110634211

Start: 1999901

End: 2001457

Strand: Reverse

Name: glpD [H]

Synonym: Meso_1861

Alternate gene names: 110634211

Gene position: 2001457-1999901 (Counterclockwise)

Preceding gene: 110634212

Following gene: 110634204

Centisome position: 45.36

GC content: 59.02

Gene sequence:

>1557_bases
ATGGAAACAGAGATGGAAAACATGCGCCCCGCCCTTACGACGTTTAATGGGCGATCCTTTGACGTGGCAATTATCGGAGG
AGGGATAAACGGATGCTCCGCTGCGCAGCATCTCGCGGCGTCCGGCTATAAGGTGCTGCTGGTCGAGAAGCATGATTTCG
CCAGCGGCGCAACCAGCCGATCTGGGCGCATCCTGCACTGCGGATTGAGATTCCTGGCGCCGGAGAAATCCGTCTCGGAA
TTCCTCTTCGCGCCAGGAAAGCTGCTAATGAAGCTGCGGACGGCGAGTGACATGGCCGTTGCGCAGGGTGAACTCTACAA
GACCATCCGGGCTTATCTGCGGCCTATGGACATCGCATTGCCCATCTACAAGCATGCCGGCTATCGGGGCTGGCATGTGG
ATATCGGAGCGGCTCTCGTGCGGGTGATGAATCGTGGCCGCAGCCCGATCAATTATCGCCGATGGAAAGGTGCCGCGTCG
CCTCATCCGTTTGTAAAGCATCTCGTCAATCAGGACGACATACGCTCCGTCGTGGCCTTCACCGACCAGCAGTTCAGGTG
GCCCGAGCGCATCGCACTCGATGCATGCCTGAACGCGGAAGACATGGGCGCGGTGATCCGCAACTACACCAAGGTGGTCC
ACCTGGAGAAAACTGGCAAGACCGACTGGAAGCTGACGCTGGAGGACAGCGAGCACACAGCCTCCGTCAACGCCCGCTAT
GTCCTGAATCTTGCAGGCATCGAGATCGACCGCACCAACCGCATGGTTCCCGGCCTGGATAATATTCCTCCTCGCGTTCG
CGCGATGAAGGGCGTCCACGTACTCATTCGCCTGCCCGAAGAATTCCGCGGTCATGGCATAGCCGGCGAAAATTCCGAGG
GTGAGCATATTTTCTGCCTTCCCTGGGGCGATTATCACTACCTCGGGCCGACTGAGACGTTCTACGACGGACATCCGGAT
GAGGTGACCCCGCTGGACGAGGACATCGATTTCATCATCCGCGAAGCACAGGCTTTGCTTCCCGGCTTGCCGATCAAGGA
AGCAAAAATTGAAATGGCCTGGGCTGGCGCGCGGCCGATTACTTTTGACCCCAGCAGGGCGAAGGGCAAGCGCCTGCCGT
TCAGCATCTTCCACGACATGGTAGACCATGGCGCGCGCAATCTCCTGGCGGTGACCTGGGGCATCATTGTCAACCATCGG
CAGACCGCCCGGAAGGTCACCCAGAAAGTCAAAGGTGTGCTGGGCGCCGCCGGTCCGGCTAAGACGATAAACTATTCTCC
GCGCGGGATACCGGCCCTGACGCCGACATCATCACAGGCGGAAATCGAACGCGCTGTGCGTCACTTCTTGACGGCAGAGC
ACGCTACCAGCGCGATTGATATCCTTTGCCGCCGCACTCCACTCTTCTGGGACAAGGCAGTGACGCTGGACTTCCTGGGT
AGGATCGTCGACGCGATGGGGGTAATCCTGCAGTGGTCAGAGGAGAGAAAGCAGGCGGAACTGGACAGCTTCGCCGAGTA
TGTGTGGCGTAACCACCGAGTGAAGCTTCCGTCCTAA

Upstream 100 bases:

>100_bases
TCGCCGCGGTCTCAGTGCTCGAAATCGCAATGGTCGTGATCGTCATGTTCGTGCTGCTCCGCATGAATAAAGGAAAAGCA
GGCCGCCTGGCTTGAAAGCA

Downstream 100 bases:

>100_bases
GACCTTCAGGCATTATGAAATTTTAACATCGCGTGCGATGCGTAGCCTGGTTGGGTTGGCAGCTTAATGCACGAATGCGT
TTGGTTCAAAATCGGCGTGA

Product: FAD dependent oxidoreductase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 518; Mature: 518

Protein sequence:

>518_residues
METEMENMRPALTTFNGRSFDVAIIGGGINGCSAAQHLAASGYKVLLVEKHDFASGATSRSGRILHCGLRFLAPEKSVSE
FLFAPGKLLMKLRTASDMAVAQGELYKTIRAYLRPMDIALPIYKHAGYRGWHVDIGAALVRVMNRGRSPINYRRWKGAAS
PHPFVKHLVNQDDIRSVVAFTDQQFRWPERIALDACLNAEDMGAVIRNYTKVVHLEKTGKTDWKLTLEDSEHTASVNARY
VLNLAGIEIDRTNRMVPGLDNIPPRVRAMKGVHVLIRLPEEFRGHGIAGENSEGEHIFCLPWGDYHYLGPTETFYDGHPD
EVTPLDEDIDFIIREAQALLPGLPIKEAKIEMAWAGARPITFDPSRAKGKRLPFSIFHDMVDHGARNLLAVTWGIIVNHR
QTARKVTQKVKGVLGAAGPAKTINYSPRGIPALTPTSSQAEIERAVRHFLTAEHATSAIDILCRRTPLFWDKAVTLDFLG
RIVDAMGVILQWSEERKQAELDSFAEYVWRNHRVKLPS

Sequences:

>Translated_518_residues
METEMENMRPALTTFNGRSFDVAIIGGGINGCSAAQHLAASGYKVLLVEKHDFASGATSRSGRILHCGLRFLAPEKSVSE
FLFAPGKLLMKLRTASDMAVAQGELYKTIRAYLRPMDIALPIYKHAGYRGWHVDIGAALVRVMNRGRSPINYRRWKGAAS
PHPFVKHLVNQDDIRSVVAFTDQQFRWPERIALDACLNAEDMGAVIRNYTKVVHLEKTGKTDWKLTLEDSEHTASVNARY
VLNLAGIEIDRTNRMVPGLDNIPPRVRAMKGVHVLIRLPEEFRGHGIAGENSEGEHIFCLPWGDYHYLGPTETFYDGHPD
EVTPLDEDIDFIIREAQALLPGLPIKEAKIEMAWAGARPITFDPSRAKGKRLPFSIFHDMVDHGARNLLAVTWGIIVNHR
QTARKVTQKVKGVLGAAGPAKTINYSPRGIPALTPTSSQAEIERAVRHFLTAEHATSAIDILCRRTPLFWDKAVTLDFLG
RIVDAMGVILQWSEERKQAELDSFAEYVWRNHRVKLPS
>Mature_518_residues
METEMENMRPALTTFNGRSFDVAIIGGGINGCSAAQHLAASGYKVLLVEKHDFASGATSRSGRILHCGLRFLAPEKSVSE
FLFAPGKLLMKLRTASDMAVAQGELYKTIRAYLRPMDIALPIYKHAGYRGWHVDIGAALVRVMNRGRSPINYRRWKGAAS
PHPFVKHLVNQDDIRSVVAFTDQQFRWPERIALDACLNAEDMGAVIRNYTKVVHLEKTGKTDWKLTLEDSEHTASVNARY
VLNLAGIEIDRTNRMVPGLDNIPPRVRAMKGVHVLIRLPEEFRGHGIAGENSEGEHIFCLPWGDYHYLGPTETFYDGHPD
EVTPLDEDIDFIIREAQALLPGLPIKEAKIEMAWAGARPITFDPSRAKGKRLPFSIFHDMVDHGARNLLAVTWGIIVNHR
QTARKVTQKVKGVLGAAGPAKTINYSPRGIPALTPTSSQAEIERAVRHFLTAEHATSAIDILCRRTPLFWDKAVTLDFLG
RIVDAMGVILQWSEERKQAELDSFAEYVWRNHRVKLPS

Specific function: Conversion Of Glycerol 3-Phosphate To Dihydroxyacetone. Uses Fumarate Or Nitrate As Electron Acceptor. [C]

COG id: COG0578

COG function: function code C; Glycerol-3-phosphate dehydrogenase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family [H]

Homologues:

Organism=Homo sapiens, GI285002233, Length=571, Percent_Identity=26.2697022767075, Blast_Score=123, Evalue=5e-28,
Organism=Homo sapiens, GI285002231, Length=571, Percent_Identity=26.2697022767075, Blast_Score=123, Evalue=5e-28,
Organism=Saccharomyces cerevisiae, GI6322036, Length=511, Percent_Identity=23.4833659491194, Blast_Score=87, Evalue=5e-18,
Organism=Drosophila melanogaster, GI161077125, Length=410, Percent_Identity=27.3170731707317, Blast_Score=94, Evalue=2e-19,
Organism=Drosophila melanogaster, GI24653942, Length=410, Percent_Identity=27.3170731707317, Blast_Score=94, Evalue=2e-19,
Organism=Drosophila melanogaster, GI24653944, Length=410, Percent_Identity=27.3170731707317, Blast_Score=94, Evalue=2e-19,
Organism=Drosophila melanogaster, GI20130025, Length=410, Percent_Identity=27.3170731707317, Blast_Score=94, Evalue=2e-19,
Organism=Drosophila melanogaster, GI24586295, Length=418, Percent_Identity=22.9665071770335, Blast_Score=72, Evalue=8e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006076
- InterPro:   IPR000447 [H]

Pfam domain/function: PF01266 DAO [H]

EC number: =1.1.5.3 [H]

Molecular weight: Translated: 57933; Mature: 57933

Theoretical pI: Translated: 9.20; Mature: 9.20

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
3.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
METEMENMRPALTTFNGRSFDVAIIGGGINGCSAAQHLAASGYKVLLVEKHDFASGATSR
CCCCHHHCCCHHEECCCCEEEEEEEECCCCCHHHHHHHHHCCEEEEEEECCCCCCCCCCC
SGRILHCGLRFLAPEKSVSEFLFAPGKLLMKLRTASDMAVAQGELYKTIRAYLRPMDIAL
CCCEEEECHHHHCCCHHHHHHHHCCCHHHHHHHCCCHHHHHHHHHHHHHHHHHCCHHHEE
PIYKHAGYRGWHVDIGAALVRVMNRGRSPINYRRWKGAASPHPFVKHLVNQDDIRSVVAF
EHHHCCCCCCEEEEHHHHHHHHHHCCCCCCCHHHCCCCCCCCHHHHHHCCHHHHHHHHHH
TDQQFRWPERIALDACLNAEDMGAVIRNYTKVVHLEKTGKTDWKLTLEDSEHTASVNARY
CCCCCCCHHHHHHHHHCCHHHHHHHHHHHHHEEEEECCCCCCEEEEEECCCCCCCCCEEE
VLNLAGIEIDRTNRMVPGLDNIPPRVRAMKGVHVLIRLPEEFRGHGIAGENSEGEHIFCL
EEEEECEEEECCCCCCCCCCCCCHHHHHHCCEEEEEECCHHHCCCCCCCCCCCCCEEEEE
PWGDYHYLGPTETFYDGHPDEVTPLDEDIDFIIREAQALLPGLPIKEAKIEMAWAGARPI
ECCCEEECCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHCCCCCCCCCEEEEEECCCCCC
TFDPSRAKGKRLPFSIFHDMVDHGARNLLAVTWGIIVNHRQTARKVTQKVKGVLGAAGPA
EECCCCCCCCCCCHHHHHHHHHHCCHHHHEEEHHHHCCCHHHHHHHHHHHHHHHCCCCCC
KTINYSPRGIPALTPTSSQAEIERAVRHFLTAEHATSAIDILCRRTPLFWDKAVTLDFLG
CCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHH
RIVDAMGVILQWSEERKQAELDSFAEYVWRNHRVKLPS
HHHHHHHHHHCCHHHHHHHHHHHHHHHHHCCCCEECCC
>Mature Secondary Structure
METEMENMRPALTTFNGRSFDVAIIGGGINGCSAAQHLAASGYKVLLVEKHDFASGATSR
CCCCHHHCCCHHEECCCCEEEEEEEECCCCCHHHHHHHHHCCEEEEEEECCCCCCCCCCC
SGRILHCGLRFLAPEKSVSEFLFAPGKLLMKLRTASDMAVAQGELYKTIRAYLRPMDIAL
CCCEEEECHHHHCCCHHHHHHHHCCCHHHHHHHCCCHHHHHHHHHHHHHHHHHCCHHHEE
PIYKHAGYRGWHVDIGAALVRVMNRGRSPINYRRWKGAASPHPFVKHLVNQDDIRSVVAF
EHHHCCCCCCEEEEHHHHHHHHHHCCCCCCCHHHCCCCCCCCHHHHHHCCHHHHHHHHHH
TDQQFRWPERIALDACLNAEDMGAVIRNYTKVVHLEKTGKTDWKLTLEDSEHTASVNARY
CCCCCCCHHHHHHHHHCCHHHHHHHHHHHHHEEEEECCCCCCEEEEEECCCCCCCCCEEE
VLNLAGIEIDRTNRMVPGLDNIPPRVRAMKGVHVLIRLPEEFRGHGIAGENSEGEHIFCL
EEEEECEEEECCCCCCCCCCCCCHHHHHHCCEEEEEECCHHHCCCCCCCCCCCCCEEEEE
PWGDYHYLGPTETFYDGHPDEVTPLDEDIDFIIREAQALLPGLPIKEAKIEMAWAGARPI
ECCCEEECCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHCCCCCCCCCEEEEEECCCCCC
TFDPSRAKGKRLPFSIFHDMVDHGARNLLAVTWGIIVNHRQTARKVTQKVKGVLGAAGPA
EECCCCCCCCCCCHHHHHHHHHHCCHHHHEEEHHHHCCCHHHHHHHHHHHHHHHCCCCCC
KTINYSPRGIPALTPTSSQAEIERAVRHFLTAEHATSAIDILCRRTPLFWDKAVTLDFLG
CCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHH
RIVDAMGVILQWSEERKQAELDSFAEYVWRNHRVKLPS
HHHHHHHHHHCCHHHHHHHHHHHHHHHHHCCCCEECCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8905231 [H]