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The map label for this gene is erpA2 [H]

Identifier: 110634166

GI number: 110634166

Start: 1946822

End: 1947172

Strand: Direct

Name: erpA2 [H]

Synonym: Meso_1815

Alternate gene names: 110634166

Gene position: 1946822-1947172 (Clockwise)

Preceding gene: 110634162

Following gene: 110634177

Centisome position: 44.12

GC content: 56.41

Gene sequence:

>351_bases
ATGGGCATCGATGCCAGGACGGAGATGAAGGGAATCGAATTGACCGATGCCGCGGCTAGACGGATCGTCAAGATTCTCGC
CGCGGAACCGGATAAGACGGCGCTTCGCGTCTCCATCGAAGGTGGCGGCTGCTCGGGCTTTTCTTACAAGTTCGATCTCG
TGGACAGCCGCAACGATGACGATCTCGTCATCGAGAAGGATGGCGCCACGGTGCTGATCGACGATCTCTCCCTCGTCTAT
ATGGGCGGTTCGGTCATCGATTTTGTCGATGACCTGATCGGGCAATCGTTTCAGATCAGGAATCCGAATGCCGTGGCCTC
CTGCGGCTGCGGAACCAGCTTTTCCATTTAA

Upstream 100 bases:

>100_bases
GATGCCGTCGAGATTTGCCGAATCTGCCATCGCCTGCGCATGTTGACTCGCCGCCTCCCCGTTCATACCTATCTGGTGTC
GACGAAAGCAAGGTGAACCC

Downstream 100 bases:

>100_bases
ACAGTTATAGCGGCCGTCGGCTTGGCCGATGCCTTGCCCCGCTCCTCTCTCGCCATAAATTCCGCAAACGGCGGCTCGCG
AGGGGGAGCAGAACCGGAGC

Product: iron-sulfur cluster assembly accessory protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 116; Mature: 115

Protein sequence:

>116_residues
MGIDARTEMKGIELTDAAARRIVKILAAEPDKTALRVSIEGGGCSGFSYKFDLVDSRNDDDLVIEKDGATVLIDDLSLVY
MGGSVIDFVDDLIGQSFQIRNPNAVASCGCGTSFSI

Sequences:

>Translated_116_residues
MGIDARTEMKGIELTDAAARRIVKILAAEPDKTALRVSIEGGGCSGFSYKFDLVDSRNDDDLVIEKDGATVLIDDLSLVY
MGGSVIDFVDDLIGQSFQIRNPNAVASCGCGTSFSI
>Mature_115_residues
GIDARTEMKGIELTDAAARRIVKILAAEPDKTALRVSIEGGGCSGFSYKFDLVDSRNDDDLVIEKDGATVLIDDLSLVYM
GGSVIDFVDDLIGQSFQIRNPNAVASCGCGTSFSI

Specific function: Required for insertion of 4Fe-4S clusters for at least ispG [H]

COG id: COG0316

COG function: function code S; Uncharacterized conserved protein

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the hesB/iscA family [H]

Homologues:

Organism=Homo sapiens, GI160420328, Length=106, Percent_Identity=46.2264150943396, Blast_Score=94, Evalue=2e-20,
Organism=Homo sapiens, GI52426768, Length=106, Percent_Identity=31.1320754716981, Blast_Score=77, Evalue=2e-15,
Organism=Escherichia coli, GI1786351, Length=106, Percent_Identity=46.2264150943396, Blast_Score=102, Evalue=9e-24,
Organism=Escherichia coli, GI1787974, Length=108, Percent_Identity=36.1111111111111, Blast_Score=88, Evalue=1e-19,
Organism=Escherichia coli, GI1788877, Length=105, Percent_Identity=37.1428571428571, Blast_Score=83, Evalue=4e-18,
Organism=Caenorhabditis elegans, GI71998452, Length=107, Percent_Identity=41.1214953271028, Blast_Score=86, Evalue=3e-18,
Organism=Caenorhabditis elegans, GI25146411, Length=114, Percent_Identity=34.2105263157895, Blast_Score=82, Evalue=4e-17,
Organism=Caenorhabditis elegans, GI193209025, Length=106, Percent_Identity=35.8490566037736, Blast_Score=81, Evalue=9e-17,
Organism=Saccharomyces cerevisiae, GI6323001, Length=105, Percent_Identity=35.2380952380952, Blast_Score=79, Evalue=1e-16,
Organism=Saccharomyces cerevisiae, GI6325324, Length=128, Percent_Identity=31.25, Blast_Score=65, Evalue=2e-12,
Organism=Drosophila melanogaster, GI24649697, Length=106, Percent_Identity=41.5094339622642, Blast_Score=85, Evalue=9e-18,
Organism=Drosophila melanogaster, GI24642263, Length=106, Percent_Identity=35.8490566037736, Blast_Score=79, Evalue=7e-16,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000361
- InterPro:   IPR016092
- InterPro:   IPR017870
- InterPro:   IPR023063 [H]

Pfam domain/function: PF01521 Fe-S_biosyn [H]

EC number: NA

Molecular weight: Translated: 12338; Mature: 12207

Theoretical pI: Translated: 4.11; Mature: 4.11

Prosite motif: PS01152 HESB

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.6 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
5.2 %Cys+Met (Translated Protein)
2.6 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
4.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MGIDARTEMKGIELTDAAARRIVKILAAEPDKTALRVSIEGGGCSGFSYKFDLVDSRNDD
CCCCCCCCCCCCEECHHHHHHHHHHHCCCCCCCEEEEEECCCCCCCCEEEEEECCCCCCC
DLVIEKDGATVLIDDLSLVYMGGSVIDFVDDLIGQSFQIRNPNAVASCGCGTSFSI
CEEEECCCCEEEEECEEEEEECCCHHHHHHHHHCCEEEECCCCCEEECCCCCCCCC
>Mature Secondary Structure 
GIDARTEMKGIELTDAAARRIVKILAAEPDKTALRVSIEGGGCSGFSYKFDLVDSRNDD
CCCCCCCCCCCEECHHHHHHHHHHHCCCCCCCEEEEEECCCCCCCCEEEEEECCCCCCC
DLVIEKDGATVLIDDLSLVYMGGSVIDFVDDLIGQSFQIRNPNAVASCGCGTSFSI
CEEEECCCCEEEEECEEEEEECCCHHHHHHHHHCCEEEECCCCCEEECCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA