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The map label for this gene is lptD [H]

Identifier: 110634110

GI number: 110634110

Start: 1879744

End: 1882104

Strand: Direct

Name: lptD [H]

Synonym: Meso_1759

Alternate gene names: 110634110

Gene position: 1879744-1882104 (Clockwise)

Preceding gene: 110634109

Following gene: 110634111

Centisome position: 42.6

GC content: 59.89

Gene sequence:

>2361_bases
ATGGCGGCTGCGGTGAGAAAGAGCCGCGCGGTCGCTCATTTGACGCGTCTGCGCTTCAAGACAGGTGTTGCGGCCGTCGC
ACTGCTGGCGTTCGCCGCTGCTGCCGCCGCTCAGGTGGCCGGCATCGACCAAGGCGACCTGCCTCAGGACGCGCAGATGC
TGCTCGCGGCCGACACCCTGGTCTATGACAACGACAACAATACCATCACCGCCGTGGGCGGGGTACAGATCGAGTATGGC
GGCTATCGCGTTGTGGCGCAGCGCGTCACCTATGACCGCAGCACCTCGCGTGTCATTGGCAGCGGCAATGTCGAGATCAT
CGACCAGGACGGCAATCGCTTCCATGCCGAAGAGGTCGACCTGACGGACGATTTGGGCGAAGGCTTCGTCCGGGCATTGA
GGGTCGAAACGGTCGACAGGACTTATTTCGGCGCCGAGAGCGCCGTGCGCGAAGGCGGCAGGCTGACCACTTTTAACAAA
GGCGTCTACACCGCCTGCGAACCCTGCGAGGAAAACCCGAATCGGCCACCGCTCTGGCAGATCAAGGCGCAGAAAATCAT
CTGGAACGGCCAGGCGAAGACCGTGCGTTTCGAGAATGCGCGTTTCGAGTTCTTCGGCCTGCCGATCGCTTATCTTCCAT
TCCTGGAAGTGGCCGATCCGACGGTGAAGCGGAAGTCCGGTTTCCTGATGCCGAGCGTGCAGGGCGGCAGCGAGCTCGGC
TATGGCCTTAAGGTTCCCTACTATTTCGCGCTTTCCCCCACCTTCGATCTCACCGCCTCGGTCACAGGCTACACCAAGCA
GGGCTTTCTGGGCGAAGCCGAGTGGCGGCAGAGATTCAATAATGGCGAATACAATCTGCGCGTGGCCGGCATCGACCAGC
AGCGGCCGGAGGAATGGGCGCCGAACGAGGTCGACTCACGTCAGACCGATCGCGGCATGATCGCCTCCAAGGGCGATTTC
CGGATTAATTCCCGCTGGTCCGCCGGCTGGAACGTGATGGTCCAGTCGGACAAGAACTTCGCCAAGACTTACGAAATTGA
GGGCTATTCGTCGTCGGTGCACCGTGACGAAGTCTACCTTACGGGCCTCAACGACCGGAACTATTTCGATCTCAGGGGCT
ACCGGTTCCAGGTGCAGGAAAACTCGGTGAATGGCCGCAACGACTCGCAGCCGCTCGTCCTGCCCAATCTCGATTACACC
TATACGCCCGACCGGGAGGTTGCGGGCGGAGAACTCACCTTTGATGTGAATGCCCAGGCGCTCCACCGCGAAGAGGGCAT
GTACACAATGAGCGATGGGACCAGGAAGCTGCAGGGTCTTCAAGGCAATTCCGGCCGCCTGACCACAGAGGCGGAGTGGC
GGCGTTCCTTCATCACCAGCGCTGGCCTCGTCCTTACCCCGATCCTGCACGCGCGCGGCGATTCGATTTTCACGGATTAT
TCGCAGGATGCTGCCGAAAGGATCCAAAGTTTCGCAAATGGCGCCGGCGCCGAAGCCGATATCCAGTCTGCCTATTACCG
CTCTATGGCGACGGCGGGCATAGAGGCGCGTTGGCCCATTCTATTTGCGGCGGCCGGTTCGGCGCACATCATCGAACCGA
TGGTGCAGCTCTTCGCACGGCCGGATGAGCCCTATCGCGATAGGCTCGGCATCCCCAATGAGGATGCGCAGTCGCTCGTC
TTCGACGCTACAACGCTTTTCGAGCGCGACAAATTTTCCGGCTATGATCGCATGGAGGGTGGTACGCGCGCGAATGTCGG
CTTCCGCTACTCGGGGAGCTTCGGTAACGGCTGGACCGCGCATGGCCTTTTCGGCCAATCCTATCATTTGGCGGGGGATA
ATCCCTACGCATCACCCGACCTTGTAAATGTCGGCGCCTATTCCGGTCTCGAGACGGACGTTTCCGACTATGTGGGATTG
ATCGGAGTAACGTTGCCGAACGGGATTTCCTTCTCGACCGGCGCCAGGCTGGACGAGCGGAGCTTTGAGCTGAGGCGCGC
GGATGTGCGTGCAGCCGGCACGGTGGGCGCGGTTACGGCGGGTGTGCAATACGCCTTTATCGATGCGCAGCCGGGCTACG
GTTTTGCGGAAGACCGGCGGGAAGTAACCGCCTCGACCTCGATTCGCTTCCATGAGAACTGGCGTGGCTTCGCATCGGGA
ACCTACGATCTTGAGAGCAGCACGCTCGTGAAAAATTCCTTCGGCTTCGCCTATGACGACGAATGCTTCACCTATCTGAT
GACATTCTCGCAAGAGCGCAATATCAGTAGCGGCGAACGCGAAAACAGCTTTGGCTTCAATATTTCATTGCGCACTTTGG
GTGATTTCGGCAGTTCCTCGAACGCTTTCGTTCAGCAATAG

Upstream 100 bases:

>100_bases
GTGACGCCGGATTCGTGCCGCCTCCTATTGCGGCCTGGACTCCGGTTATGGTGGCAATGTTTTTCGGGGTTACTTTCCTT
TTATTCCGAGAGGACGGTTA

Downstream 100 bases:

>100_bases
GCATTGTGACAGCGTCATAGTTTCGCCTATCAAGAAAGCGATGCTAAATTCACGATTGCTGAATTTCATATGATGTGAAG
GAGAATGGAACATGTCTGTG

Product: organic solvent tolerance protein

Products: NA

Alternate protein names: Organic solvent tolerance protein [H]

Number of amino acids: Translated: 786; Mature: 785

Protein sequence:

>786_residues
MAAAVRKSRAVAHLTRLRFKTGVAAVALLAFAAAAAAQVAGIDQGDLPQDAQMLLAADTLVYDNDNNTITAVGGVQIEYG
GYRVVAQRVTYDRSTSRVIGSGNVEIIDQDGNRFHAEEVDLTDDLGEGFVRALRVETVDRTYFGAESAVREGGRLTTFNK
GVYTACEPCEENPNRPPLWQIKAQKIIWNGQAKTVRFENARFEFFGLPIAYLPFLEVADPTVKRKSGFLMPSVQGGSELG
YGLKVPYYFALSPTFDLTASVTGYTKQGFLGEAEWRQRFNNGEYNLRVAGIDQQRPEEWAPNEVDSRQTDRGMIASKGDF
RINSRWSAGWNVMVQSDKNFAKTYEIEGYSSSVHRDEVYLTGLNDRNYFDLRGYRFQVQENSVNGRNDSQPLVLPNLDYT
YTPDREVAGGELTFDVNAQALHREEGMYTMSDGTRKLQGLQGNSGRLTTEAEWRRSFITSAGLVLTPILHARGDSIFTDY
SQDAAERIQSFANGAGAEADIQSAYYRSMATAGIEARWPILFAAAGSAHIIEPMVQLFARPDEPYRDRLGIPNEDAQSLV
FDATTLFERDKFSGYDRMEGGTRANVGFRYSGSFGNGWTAHGLFGQSYHLAGDNPYASPDLVNVGAYSGLETDVSDYVGL
IGVTLPNGISFSTGARLDERSFELRRADVRAAGTVGAVTAGVQYAFIDAQPGYGFAEDRREVTASTSIRFHENWRGFASG
TYDLESSTLVKNSFGFAYDDECFTYLMTFSQERNISSGERENSFGFNISLRTLGDFGSSSNAFVQQ

Sequences:

>Translated_786_residues
MAAAVRKSRAVAHLTRLRFKTGVAAVALLAFAAAAAAQVAGIDQGDLPQDAQMLLAADTLVYDNDNNTITAVGGVQIEYG
GYRVVAQRVTYDRSTSRVIGSGNVEIIDQDGNRFHAEEVDLTDDLGEGFVRALRVETVDRTYFGAESAVREGGRLTTFNK
GVYTACEPCEENPNRPPLWQIKAQKIIWNGQAKTVRFENARFEFFGLPIAYLPFLEVADPTVKRKSGFLMPSVQGGSELG
YGLKVPYYFALSPTFDLTASVTGYTKQGFLGEAEWRQRFNNGEYNLRVAGIDQQRPEEWAPNEVDSRQTDRGMIASKGDF
RINSRWSAGWNVMVQSDKNFAKTYEIEGYSSSVHRDEVYLTGLNDRNYFDLRGYRFQVQENSVNGRNDSQPLVLPNLDYT
YTPDREVAGGELTFDVNAQALHREEGMYTMSDGTRKLQGLQGNSGRLTTEAEWRRSFITSAGLVLTPILHARGDSIFTDY
SQDAAERIQSFANGAGAEADIQSAYYRSMATAGIEARWPILFAAAGSAHIIEPMVQLFARPDEPYRDRLGIPNEDAQSLV
FDATTLFERDKFSGYDRMEGGTRANVGFRYSGSFGNGWTAHGLFGQSYHLAGDNPYASPDLVNVGAYSGLETDVSDYVGL
IGVTLPNGISFSTGARLDERSFELRRADVRAAGTVGAVTAGVQYAFIDAQPGYGFAEDRREVTASTSIRFHENWRGFASG
TYDLESSTLVKNSFGFAYDDECFTYLMTFSQERNISSGERENSFGFNISLRTLGDFGSSSNAFVQQ
>Mature_785_residues
AAAVRKSRAVAHLTRLRFKTGVAAVALLAFAAAAAAQVAGIDQGDLPQDAQMLLAADTLVYDNDNNTITAVGGVQIEYGG
YRVVAQRVTYDRSTSRVIGSGNVEIIDQDGNRFHAEEVDLTDDLGEGFVRALRVETVDRTYFGAESAVREGGRLTTFNKG
VYTACEPCEENPNRPPLWQIKAQKIIWNGQAKTVRFENARFEFFGLPIAYLPFLEVADPTVKRKSGFLMPSVQGGSELGY
GLKVPYYFALSPTFDLTASVTGYTKQGFLGEAEWRQRFNNGEYNLRVAGIDQQRPEEWAPNEVDSRQTDRGMIASKGDFR
INSRWSAGWNVMVQSDKNFAKTYEIEGYSSSVHRDEVYLTGLNDRNYFDLRGYRFQVQENSVNGRNDSQPLVLPNLDYTY
TPDREVAGGELTFDVNAQALHREEGMYTMSDGTRKLQGLQGNSGRLTTEAEWRRSFITSAGLVLTPILHARGDSIFTDYS
QDAAERIQSFANGAGAEADIQSAYYRSMATAGIEARWPILFAAAGSAHIIEPMVQLFARPDEPYRDRLGIPNEDAQSLVF
DATTLFERDKFSGYDRMEGGTRANVGFRYSGSFGNGWTAHGLFGQSYHLAGDNPYASPDLVNVGAYSGLETDVSDYVGLI
GVTLPNGISFSTGARLDERSFELRRADVRAAGTVGAVTAGVQYAFIDAQPGYGFAEDRREVTASTSIRFHENWRGFASGT
YDLESSTLVKNSFGFAYDDECFTYLMTFSQERNISSGERENSFGFNISLRTLGDFGSSSNAFVQQ

Specific function: Involved in the assembly of LPS in the outer leaflet of the outer membrane. Determines N-hexane tolerance and is involved in outer membrane permeability. Essential for envelope biogenesis [H]

COG id: COG1452

COG function: function code M; Organic solvent tolerance protein OstA

Gene ontology:

Cell location: Cell outer membrane [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the lptD family [H]

Homologues:

None

Paralogues:

None

Copy number: 60 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR020889
- InterPro:   IPR007543 [H]

Pfam domain/function: PF04453 OstA_C [H]

EC number: NA

Molecular weight: Translated: 86795; Mature: 86664

Theoretical pI: Translated: 4.76; Mature: 4.76

Prosite motif: PS01039 SBP_BACTERIAL_3

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
1.4 %Met     (Translated Protein)
1.8 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
1.3 %Met     (Mature Protein)
1.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAAAVRKSRAVAHLTRLRFKTGVAAVALLAFAAAAAAQVAGIDQGDLPQDAQMLLAADTL
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHEEEEEEEE
VYDNDNNTITAVGGVQIEYGGYRVVAQRVTYDRSTSRVIGSGNVEIIDQDGNRFHAEEVD
EEECCCCEEEEECCEEEEECCEEEEEEEECCCCCCCEEEECCCEEEEECCCCEEECCCCC
LTDDLGEGFVRALRVETVDRTYFGAESAVREGGRLTTFNKGVYTACEPCEENPNRPPLWQ
CCHHHHHHHHHHHHHHHHCCHHCCCHHHHHCCCCEEEECCCCEEECCCHHCCCCCCCEEE
IKAQKIIWNGQAKTVRFENARFEFFGLPIAYLPFLEVADPTVKRKSGFLMPSVQGGSELG
EEEEEEEECCCCEEEEEECCEEEEECCCHHHHCHHHHCCCCHHHCCCCCCCCCCCCCCCC
YGLKVPYYFALSPTFDLTASVTGYTKQGFLGEAEWRQRFNNGEYNLRVAGIDQQRPEEWA
CCEECCEEEEECCCCCEEEEECCCCCCCCCCCHHHHHHCCCCCEEEEEECCCCCCCCCCC
PNEVDSRQTDRGMIASKGDFRINSRWSAGWNVMVQSDKNFAKTYEIEGYSSSVHRDEVYL
CCCCCCCCCCCCCEECCCCEEECCEECCCCEEEEECCCCCEEEEEECCCCCCCCCCEEEE
TGLNDRNYFDLRGYRFQVQENSVNGRNDSQPLVLPNLDYTYTPDREVAGGELTFDVNAQA
EECCCCCEEEECCEEEEEEECCCCCCCCCCCEEECCCCCEECCCCCCCCCEEEEECCHHH
LHREEGMYTMSDGTRKLQGLQGNSGRLTTEAEWRRSFITSAGLVLTPILHARGDSIFTDY
HHHCCCCEEECCCCHHHCCCCCCCCEEECHHHHHHHHHHCCCHHHHHHHHHCCCCEECCC
SQDAAERIQSFANGAGAEADIQSAYYRSMATAGIEARWPILFAAAGSAHIIEPMVQLFAR
CHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHCCCCCCCCEEEEECCCCHHHHHHHHHHCC
PDEPYRDRLGIPNEDAQSLVFDATTLFERDKFSGYDRMEGGTRANVGFRYSGSFGNGWTA
CCCCHHHHCCCCCCCCHHEEEEHHHHHHCCCCCCCCCCCCCCCCCCEEEEECCCCCCEEE
HGLFGQSYHLAGDNPYASPDLVNVGAYSGLETDVSDYVGLIGVTLPNGISFSTGARLDER
CCCCCCEEEECCCCCCCCCCEEECCCCCCCCCCHHHHHEEEEEECCCCCCCCCCCCCCCH
SFELRRADVRAAGTVGAVTAGVQYAFIDAQPGYGFAEDRREVTASTSIRFHENWRGFASG
HHHHHHHHHHHCCCHHHHCCCEEEEEEECCCCCCCHHHHHHEEEEEEEEEECCCCCCCCC
TYDLESSTLVKNSFGFAYDDECFTYLMTFSQERNISSGERENSFGFNISLRTLGDFGSSS
EEECCCCEEEECCCCCEECHHHHHHHHHHHCCCCCCCCCCCCCCEEEEEEEEECCCCCCC
NAFVQQ
CCCCCC
>Mature Secondary Structure 
AAAVRKSRAVAHLTRLRFKTGVAAVALLAFAAAAAAQVAGIDQGDLPQDAQMLLAADTL
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHEEEEEEEE
VYDNDNNTITAVGGVQIEYGGYRVVAQRVTYDRSTSRVIGSGNVEIIDQDGNRFHAEEVD
EEECCCCEEEEECCEEEEECCEEEEEEEECCCCCCCEEEECCCEEEEECCCCEEECCCCC
LTDDLGEGFVRALRVETVDRTYFGAESAVREGGRLTTFNKGVYTACEPCEENPNRPPLWQ
CCHHHHHHHHHHHHHHHHCCHHCCCHHHHHCCCCEEEECCCCEEECCCHHCCCCCCCEEE
IKAQKIIWNGQAKTVRFENARFEFFGLPIAYLPFLEVADPTVKRKSGFLMPSVQGGSELG
EEEEEEEECCCCEEEEEECCEEEEECCCHHHHCHHHHCCCCHHHCCCCCCCCCCCCCCCC
YGLKVPYYFALSPTFDLTASVTGYTKQGFLGEAEWRQRFNNGEYNLRVAGIDQQRPEEWA
CCEECCEEEEECCCCCEEEEECCCCCCCCCCCHHHHHHCCCCCEEEEEECCCCCCCCCCC
PNEVDSRQTDRGMIASKGDFRINSRWSAGWNVMVQSDKNFAKTYEIEGYSSSVHRDEVYL
CCCCCCCCCCCCCEECCCCEEECCEECCCCEEEEECCCCCEEEEEECCCCCCCCCCEEEE
TGLNDRNYFDLRGYRFQVQENSVNGRNDSQPLVLPNLDYTYTPDREVAGGELTFDVNAQA
EECCCCCEEEECCEEEEEEECCCCCCCCCCCEEECCCCCEECCCCCCCCCEEEEECCHHH
LHREEGMYTMSDGTRKLQGLQGNSGRLTTEAEWRRSFITSAGLVLTPILHARGDSIFTDY
HHHCCCCEEECCCCHHHCCCCCCCCEEECHHHHHHHHHHCCCHHHHHHHHHCCCCEECCC
SQDAAERIQSFANGAGAEADIQSAYYRSMATAGIEARWPILFAAAGSAHIIEPMVQLFAR
CHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHCCCCCCCCEEEEECCCCHHHHHHHHHHCC
PDEPYRDRLGIPNEDAQSLVFDATTLFERDKFSGYDRMEGGTRANVGFRYSGSFGNGWTA
CCCCHHHHCCCCCCCCHHEEEEHHHHHHCCCCCCCCCCCCCCCCCCEEEEECCCCCCEEE
HGLFGQSYHLAGDNPYASPDLVNVGAYSGLETDVSDYVGLIGVTLPNGISFSTGARLDER
CCCCCCEEEECCCCCCCCCCEEECCCCCCCCCCHHHHHEEEEEECCCCCCCCCCCCCCCH
SFELRRADVRAAGTVGAVTAGVQYAFIDAQPGYGFAEDRREVTASTSIRFHENWRGFASG
HHHHHHHHHHHCCCHHHHCCCEEEEEEECCCCCCCHHHHHHEEEEEEEEEECCCCCCCCC
TYDLESSTLVKNSFGFAYDDECFTYLMTFSQERNISSGERENSFGFNISLRTLGDFGSSS
EEECCCCEEEECCCCCEECHHHHHHHHHHHCCCCCCCCCCCCCCEEEEEEEEECCCCCCC
NAFVQQ
CCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: NA