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The map label for this gene is yhcK [H]

Identifier: 110634093

GI number: 110634093

Start: 1862413

End: 1863192

Strand: Reverse

Name: yhcK [H]

Synonym: Meso_1742

Alternate gene names: 110634093

Gene position: 1863192-1862413 (Counterclockwise)

Preceding gene: 110634094

Following gene: 110634091

Centisome position: 42.23

GC content: 58.21

Gene sequence:

>780_bases
ATGCGTTTCCATAAGGCAGAATCCGCATTTTTTGTTTTCATCGGTCTGGTTCTCTCGGCCGGCGTCACGCTGGCTGGCGC
CTATGGCGTCATGAGCACCAGTACCCACGCGGCGCTTGCGAAAGAAATCGACGAGTTTGCCTGGCTTTTGCTCGCGACGG
GCATATTGCTCGGCGCGGCAATCATTTTCGGCCTATTCTTCATTTATCCGATCATTCGGACCCAGGTGAAGGTGGAAGGC
AAGCTTCGAGCCATGACCGAGACGTTGAGCGCGTGGTCGGAATCGCTGGAATACGCCGCCTTCACGGACAGTCTCACCGG
AACGTATAATCGCCGGTACTTCGATGATGCCCTGGCCGAATATTTGCTGGAGTTCGGCCGCATCCATAAGCCTGTGGGGC
TGATCATCCTCGATCTCGACCACTTCAAGCAGGTTAACGACGCCTATGGTCATGATATCGGCGACGAGGTTTTGCGCCGG
GTCGCCCGCTGTCTGCAAGAGCTGACGCGCCATGATGACGTGGTGGCGCGTCTCGGAGGAGAGGAGTTCGCAATCCTCGC
GCCGAATATGGACGAGCAGGGGCTGGCGAAACTGGGAGAGCGCGCTCGCCAGGCCATATCGGCGCTGGCCGTGAATGCGG
GCAATATCCGGCTTCGAATCTCAACCAGCGTGGGCCTGGCAGTGTGGGACGGGAACGAAAGTGTGGAGGAATTTTATCGC
CGCGCTGACCGCATGCTCTATCAGGCGAAACGCATGGGAAGGAATCGCGTTTGCGCCTGA

Upstream 100 bases:

>100_bases
GGAAAAATTATGGAAAGCCACAATCTTCAGTTTTCAATTAATTTCATATAAGCCCTCTCTGTGCCAACAACTTACAGATG
TATTTTGCGTGGGTGGGGGC

Downstream 100 bases:

>100_bases
GGAGCCTCGGATCTCGCCATCGCTGACTAGCGCTGGTTTCTTTCGTCCTCCACCAGATCGTCAAGGAGGCGGCTCATTTC
CTCCTCGATCGAGGTTTCCT

Product: diguanylate cyclase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 259; Mature: 259

Protein sequence:

>259_residues
MRFHKAESAFFVFIGLVLSAGVTLAGAYGVMSTSTHAALAKEIDEFAWLLLATGILLGAAIIFGLFFIYPIIRTQVKVEG
KLRAMTETLSAWSESLEYAAFTDSLTGTYNRRYFDDALAEYLLEFGRIHKPVGLIILDLDHFKQVNDAYGHDIGDEVLRR
VARCLQELTRHDDVVARLGGEEFAILAPNMDEQGLAKLGERARQAISALAVNAGNIRLRISTSVGLAVWDGNESVEEFYR
RADRMLYQAKRMGRNRVCA

Sequences:

>Translated_259_residues
MRFHKAESAFFVFIGLVLSAGVTLAGAYGVMSTSTHAALAKEIDEFAWLLLATGILLGAAIIFGLFFIYPIIRTQVKVEG
KLRAMTETLSAWSESLEYAAFTDSLTGTYNRRYFDDALAEYLLEFGRIHKPVGLIILDLDHFKQVNDAYGHDIGDEVLRR
VARCLQELTRHDDVVARLGGEEFAILAPNMDEQGLAKLGERARQAISALAVNAGNIRLRISTSVGLAVWDGNESVEEFYR
RADRMLYQAKRMGRNRVCA
>Mature_259_residues
MRFHKAESAFFVFIGLVLSAGVTLAGAYGVMSTSTHAALAKEIDEFAWLLLATGILLGAAIIFGLFFIYPIIRTQVKVEG
KLRAMTETLSAWSESLEYAAFTDSLTGTYNRRYFDDALAEYLLEFGRIHKPVGLIILDLDHFKQVNDAYGHDIGDEVLRR
VARCLQELTRHDDVVARLGGEEFAILAPNMDEQGLAKLGERARQAISALAVNAGNIRLRISTSVGLAVWDGNESVEEFYR
RADRMLYQAKRMGRNRVCA

Specific function: Unknown

COG id: COG2199

COG function: function code T; FOG: GGDEF domain

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Non Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 GGDEF domain [H]

Homologues:

Organism=Escherichia coli, GI87081881, Length=166, Percent_Identity=39.7590361445783, Blast_Score=120, Evalue=7e-29,
Organism=Escherichia coli, GI1787262, Length=159, Percent_Identity=37.7358490566038, Blast_Score=113, Evalue=1e-26,
Organism=Escherichia coli, GI1786584, Length=194, Percent_Identity=32.9896907216495, Blast_Score=107, Evalue=1e-24,
Organism=Escherichia coli, GI145693134, Length=156, Percent_Identity=35.8974358974359, Blast_Score=107, Evalue=1e-24,
Organism=Escherichia coli, GI87082007, Length=210, Percent_Identity=33.8095238095238, Blast_Score=102, Evalue=2e-23,
Organism=Escherichia coli, GI1787541, Length=167, Percent_Identity=39.5209580838323, Blast_Score=100, Evalue=1e-22,
Organism=Escherichia coli, GI1787816, Length=157, Percent_Identity=36.3057324840764, Blast_Score=91, Evalue=1e-19,
Organism=Escherichia coli, GI1788381, Length=164, Percent_Identity=34.7560975609756, Blast_Score=90, Evalue=1e-19,
Organism=Escherichia coli, GI1787802, Length=161, Percent_Identity=32.9192546583851, Blast_Score=86, Evalue=2e-18,
Organism=Escherichia coli, GI1788085, Length=188, Percent_Identity=29.2553191489362, Blast_Score=84, Evalue=1e-17,
Organism=Escherichia coli, GI87081974, Length=155, Percent_Identity=29.6774193548387, Blast_Score=79, Evalue=3e-16,
Organism=Escherichia coli, GI1787056, Length=165, Percent_Identity=35.1515151515151, Blast_Score=76, Evalue=3e-15,
Organism=Escherichia coli, GI87081977, Length=170, Percent_Identity=30.5882352941176, Blast_Score=75, Evalue=3e-15,
Organism=Escherichia coli, GI1788956, Length=163, Percent_Identity=31.9018404907975, Blast_Score=66, Evalue=2e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001054
- InterPro:   IPR000160
- InterPro:   IPR011620 [H]

Pfam domain/function: PF07694 5TM-5TMR_LYT; PF00990 GGDEF [H]

EC number: NA

Molecular weight: Translated: 28828; Mature: 28828

Theoretical pI: Translated: 6.52; Mature: 6.52

Prosite motif: PS50887 GGDEF

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRFHKAESAFFVFIGLVLSAGVTLAGAYGVMSTSTHAALAKEIDEFAWLLLATGILLGAA
CCCCCHHHHHHHHHHHHHHCCHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHH
IIFGLFFIYPIIRTQVKVEGKLRAMTETLSAWSESLEYAAFTDSLTGTYNRRYFDDALAE
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHH
YLLEFGRIHKPVGLIILDLDHFKQVNDAYGHDIGDEVLRRVARCLQELTRHDDVVARLGG
HHHHHHHHCCCHHEEEECHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCC
EEFAILAPNMDEQGLAKLGERARQAISALAVNAGNIRLRISTSVGLAVWDGNESVEEFYR
CCEEEECCCCCHHHHHHHHHHHHHHHHHHHCCCCCEEEEEECCCEEEEECCCHHHHHHHH
RADRMLYQAKRMGRNRVCA
HHHHHHHHHHHCCCCCCCC
>Mature Secondary Structure
MRFHKAESAFFVFIGLVLSAGVTLAGAYGVMSTSTHAALAKEIDEFAWLLLATGILLGAA
CCCCCHHHHHHHHHHHHHHCCHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHH
IIFGLFFIYPIIRTQVKVEGKLRAMTETLSAWSESLEYAAFTDSLTGTYNRRYFDDALAE
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHH
YLLEFGRIHKPVGLIILDLDHFKQVNDAYGHDIGDEVLRRVARCLQELTRHDDVVARLGG
HHHHHHHHCCCHHEEEECHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCC
EEFAILAPNMDEQGLAKLGERARQAISALAVNAGNIRLRISTSVGLAVWDGNESVEEFYR
CCEEEECCCCCHHHHHHHHHHHHHHHHHHHCCCCCEEEEEECCCEEEEECCCHHHHHHHH
RADRMLYQAKRMGRNRVCA
HHHHHHHHHHHCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 8969498; 9384377 [H]