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The map label for this gene is aroQ

Identifier: 110634066

GI number: 110634066

Start: 1839107

End: 1839544

Strand: Direct

Name: aroQ

Synonym: Meso_1714

Alternate gene names: 110634066

Gene position: 1839107-1839544 (Clockwise)

Preceding gene: 110634065

Following gene: 110634067

Centisome position: 41.68

GC content: 61.19

Gene sequence:

>438_bases
ATGGCGAAAACGGTATACGTTCTCAACGGACCGAACCTGAACACGCTCGGCAAGCGTGAGCCCGGAATCTATGGCGGCAA
GACCCTGGCCGATATCGAGGCGGACTGCCGCGCCGCTGCAGCAGGTCTTGGCTTGGAGGTCGAATTCCGCCAGTCCAACC
ACGAAGGCATGCTGATCGATTGGATTCATGAAGCTGGCGAGCGCGGCGCCGGCATCGTCCTCAATCCCGGAGCATACGGG
CATACGTCGATTGCGCTCCACGATGCGATCAGGGCGGTGAGCCCGCTACCGGTGATCGAGGTGCATCTATCGAATATTCA
CGCGCGCGAGCCGTTCCGGCACAGAACGATGACGGCTCCGGTCGTGGCGGGGATGATCTGCGGTCTCGGACCGATCGGAT
ATACGCTGGCGCTTCAGGCACTGGCGGCAAGGTTATAA

Upstream 100 bases:

>100_bases
CTTTGTCCCTGCCTGGAACGGGGGAATAGCGTATTTGCGCTCTTTCCGCAGCCGCCGAAGCCGATTATAGAGGGCCAGCG
GAATGCCTCGGGACTAGATA

Downstream 100 bases:

>100_bases
TTGGTCGCTGAGGCCAAGGGGATAAGATGTCGATGAAGAAGAACGGTGTGGATCAGCAGCTCATTCGCGAATTGGCGAAC
ATTCTCGACGAGACGCGCCT

Product: 3-dehydroquinate dehydratase

Products: NA

Alternate protein names: 3-dehydroquinase; Type II DHQase

Number of amino acids: Translated: 145; Mature: 144

Protein sequence:

>145_residues
MAKTVYVLNGPNLNTLGKREPGIYGGKTLADIEADCRAAAAGLGLEVEFRQSNHEGMLIDWIHEAGERGAGIVLNPGAYG
HTSIALHDAIRAVSPLPVIEVHLSNIHAREPFRHRTMTAPVVAGMICGLGPIGYTLALQALAARL

Sequences:

>Translated_145_residues
MAKTVYVLNGPNLNTLGKREPGIYGGKTLADIEADCRAAAAGLGLEVEFRQSNHEGMLIDWIHEAGERGAGIVLNPGAYG
HTSIALHDAIRAVSPLPVIEVHLSNIHAREPFRHRTMTAPVVAGMICGLGPIGYTLALQALAARL
>Mature_144_residues
AKTVYVLNGPNLNTLGKREPGIYGGKTLADIEADCRAAAAGLGLEVEFRQSNHEGMLIDWIHEAGERGAGIVLNPGAYGH
TSIALHDAIRAVSPLPVIEVHLSNIHAREPFRHRTMTAPVVAGMICGLGPIGYTLALQALAARL

Specific function: Catalyzes a trans-dehydration via an enolate intermediate

COG id: COG0757

COG function: function code E; 3-dehydroquinate dehydratase II

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the type-II 3-dehydroquinase family

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): AROQ_MESSB (Q11HL6)

Other databases:

- EMBL:   CP000390
- RefSeq:   YP_674274.1
- ProteinModelPortal:   Q11HL6
- SMR:   Q11HL6
- STRING:   Q11HL6
- GeneID:   4181344
- GenomeReviews:   CP000390_GR
- KEGG:   mes:Meso_1714
- NMPDR:   fig|266779.1.peg.3797
- eggNOG:   COG0757
- HOGENOM:   HBG284657
- OMA:   IMVINGP
- ProtClustDB:   PRK05395
- BioCyc:   MSP266779:MESO_1714-MONOMER
- HAMAP:   MF_00169
- InterPro:   IPR001874
- InterPro:   IPR018509
- Gene3D:   G3DSA:3.40.50.9100
- PANTHER:   PTHR21272
- PIRSF:   PIRSF001399
- ProDom:   PD004527
- TIGRFAMs:   TIGR01088

Pfam domain/function: PF01220 DHquinase_II; SSF52304 DHquinase_II

EC number: =4.2.1.10

Molecular weight: Translated: 15368; Mature: 15237

Theoretical pI: Translated: 7.22; Mature: 7.22

Prosite motif: PS01029 DEHYDROQUINASE_II

Important sites: ACT_SITE 24-24 ACT_SITE 102-102 BINDING 75-75 BINDING 81-81 BINDING 88-88 BINDING 113-113

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
4.1 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
3.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAKTVYVLNGPNLNTLGKREPGIYGGKTLADIEADCRAAAAGLGLEVEFRQSNHEGMLID
CCEEEEEEECCCCCCCCCCCCCCCCCCEEECCHHHHHHHHHCCCEEEEEECCCCCCEEEE
WIHEAGERGAGIVLNPGAYGHTSIALHDAIRAVSPLPVIEVHLSNIHAREPFRHRTMTAP
EHHHCCCCCCCEEECCCCCCCCHHHHHHHHHHCCCCCEEEEEECCCCCCCCCHHCCCHHH
VVAGMICGLGPIGYTLALQALAARL
HHHHHHHCCCHHHHHHHHHHHHHCC
>Mature Secondary Structure 
AKTVYVLNGPNLNTLGKREPGIYGGKTLADIEADCRAAAAGLGLEVEFRQSNHEGMLID
CEEEEEEECCCCCCCCCCCCCCCCCCEEECCHHHHHHHHHCCCEEEEEECCCCCCEEEE
WIHEAGERGAGIVLNPGAYGHTSIALHDAIRAVSPLPVIEVHLSNIHAREPFRHRTMTAP
EHHHCCCCCCCEEECCCCCCCCHHHHHHHHHHCCCCCEEEEEECCCCCCCCCHHCCCHHH
VVAGMICGLGPIGYTLALQALAARL
HHHHHHHCCCHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA