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The map label for this gene is gsiC [H]

Identifier: 110633858

GI number: 110633858

Start: 1602679

End: 1603626

Strand: Reverse

Name: gsiC [H]

Synonym: Meso_1505

Alternate gene names: 110633858

Gene position: 1603626-1602679 (Counterclockwise)

Preceding gene: 110633859

Following gene: 110633857

Centisome position: 36.34

GC content: 59.6

Gene sequence:

>948_bases
ATGGCAATGCTCAACTTCATCTTCCGGCGCGTTCTTGCGGCGATCCCGACCTTGCTGATCCTGTCGGTATTCGTTTTCCT
GTTGTTGAAGCTGCTTCCCGGCGATCCCGCGCTGGCACTCGCTGGTGAGGACCGCGACCCCGCCGTGATCGAAAGCATCC
GTGTCAAATACGGTCTCGACCAGCCACTTCCGGTCCAGTATTTCAAATGGCTTGGCGATATCCTTCAGGGTGATTTCGGC
GTCTCGATCCGCACCAAGATGTCGATCGGCGAAATGCTGGCGCAGCGCCTTCCGGTCACACTCCAACTCTCCCTGCAGGC
AATGCTGATCGCCATCATCATCGGCATTCCGGCAGGTGTCTACGCCGCGATCCGGCGTGGCAGCTATGTCGATGTCGCGG
TTTCGACCGTCGGCCTTGCCGGCCTTTCGGTGCCGAGCTTCTGGCTTGGCATTATGTTGATCATGGCCTTTGCGGTCTCG
CTCGGATGGCTGCCCAGTGGCGGCTTTGTCAACTTCTCCGACGCGCCGCTCGAAAACCTTCGCTACACGCTGCTGCCCAG
TCTCGTGCTTGGCACGGCAGCCGCCGCCATCATCATGCGTCACACACGCAATTCGATGCTGTCGGTGCTCAAGCAGGATT
ATATCCGCACCGCCCGCGCGAAAGGCCTGAAGGAGCGCATCGTCATCATTCGCCATGCGTTGCGCAACGGCCTAATTCCG
ATCGTCACTACGGGTACGCTGCATCTTGGCGAGCTTTTGTCCGGCGCGGTCCTGACCGAGCAGGTCTTCGGTATTCCCGG
TTTCGGCAAGATGATCGTCGACGGCGTGTTCAGCCGCGATTACGCGGTCGTGCAGGCGGTGATCCTGTGCTCCGCCGCGA
TTTTCCTGATCCTGAGCCTGCTCGCCGATATCCTTTATGTGAAACTCAGCCCGAGGTTGCAGGCATGA

Upstream 100 bases:

>100_bases
CTGATGGTCTTCTGCGCGTAGCTGGCGTCAAGCCCGCGAACTGATATCCCCATGACCGGGCGGGCGCGTTGTCCGCTCGG
TCATTTGGGAGGCTTTCGGC

Downstream 100 bases:

>100_bases
GCGCAGCTGTCGCCGCCCCGGCCAATACCGGATCCCGCAACCGCAGCTTCCTGCTGCGCGTCCTCTCACAGCGCAGCGCG
GTCATCGGCCTGGCGATCGT

Product: binding-protein-dependent transport systems inner membrane component

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 315; Mature: 314

Protein sequence:

>315_residues
MAMLNFIFRRVLAAIPTLLILSVFVFLLLKLLPGDPALALAGEDRDPAVIESIRVKYGLDQPLPVQYFKWLGDILQGDFG
VSIRTKMSIGEMLAQRLPVTLQLSLQAMLIAIIIGIPAGVYAAIRRGSYVDVAVSTVGLAGLSVPSFWLGIMLIMAFAVS
LGWLPSGGFVNFSDAPLENLRYTLLPSLVLGTAAAAIIMRHTRNSMLSVLKQDYIRTARAKGLKERIVIIRHALRNGLIP
IVTTGTLHLGELLSGAVLTEQVFGIPGFGKMIVDGVFSRDYAVVQAVILCSAAIFLILSLLADILYVKLSPRLQA

Sequences:

>Translated_315_residues
MAMLNFIFRRVLAAIPTLLILSVFVFLLLKLLPGDPALALAGEDRDPAVIESIRVKYGLDQPLPVQYFKWLGDILQGDFG
VSIRTKMSIGEMLAQRLPVTLQLSLQAMLIAIIIGIPAGVYAAIRRGSYVDVAVSTVGLAGLSVPSFWLGIMLIMAFAVS
LGWLPSGGFVNFSDAPLENLRYTLLPSLVLGTAAAAIIMRHTRNSMLSVLKQDYIRTARAKGLKERIVIIRHALRNGLIP
IVTTGTLHLGELLSGAVLTEQVFGIPGFGKMIVDGVFSRDYAVVQAVILCSAAIFLILSLLADILYVKLSPRLQA
>Mature_314_residues
AMLNFIFRRVLAAIPTLLILSVFVFLLLKLLPGDPALALAGEDRDPAVIESIRVKYGLDQPLPVQYFKWLGDILQGDFGV
SIRTKMSIGEMLAQRLPVTLQLSLQAMLIAIIIGIPAGVYAAIRRGSYVDVAVSTVGLAGLSVPSFWLGIMLIMAFAVSL
GWLPSGGFVNFSDAPLENLRYTLLPSLVLGTAAAAIIMRHTRNSMLSVLKQDYIRTARAKGLKERIVIIRHALRNGLIPI
VTTGTLHLGELLSGAVLTEQVFGIPGFGKMIVDGVFSRDYAVVQAVILCSAAIFLILSLLADILYVKLSPRLQA

Specific function: Part of the ABC transporter complex gsiABCD involved in glutathione import. Probably responsible for the translocation of the substrate across the membrane [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 ABC transmembrane type-1 domain [H]

Homologues:

Organism=Escherichia coli, GI1787053, Length=312, Percent_Identity=43.2692307692308, Blast_Score=272, Evalue=2e-74,
Organism=Escherichia coli, GI1789965, Length=340, Percent_Identity=39.1176470588235, Blast_Score=238, Evalue=4e-64,
Organism=Escherichia coli, GI1787497, Length=314, Percent_Identity=36.9426751592357, Blast_Score=218, Evalue=5e-58,
Organism=Escherichia coli, GI1789888, Length=315, Percent_Identity=36.8253968253968, Blast_Score=215, Evalue=3e-57,
Organism=Escherichia coli, GI1787761, Length=305, Percent_Identity=38.0327868852459, Blast_Score=183, Evalue=1e-47,
Organism=Escherichia coli, GI1787550, Length=265, Percent_Identity=29.811320754717, Blast_Score=149, Evalue=2e-37,
Organism=Escherichia coli, GI1788504, Length=357, Percent_Identity=28.5714285714286, Blast_Score=140, Evalue=7e-35,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000515 [H]

Pfam domain/function: PF00528 BPD_transp_1 [H]

EC number: NA

Molecular weight: Translated: 34096; Mature: 33964

Theoretical pI: Translated: 10.16; Mature: 10.16

Prosite motif: PS50928 ABC_TM1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
3.2 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
2.9 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAMLNFIFRRVLAAIPTLLILSVFVFLLLKLLPGDPALALAGEDRDPAVIESIRVKYGLD
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEECCCCCCHHHHHHHHHHHCCC
QPLPVQYFKWLGDILQGDFGVSIRTKMSIGEMLAQRLPVTLQLSLQAMLIAIIIGIPAGV
CCCCHHHHHHHHHHHCCCCCCEEEHHHHHHHHHHHHCCEEEEHHHHHHHHHHHHHCCHHH
YAAIRRGSYVDVAVSTVGLAGLSVPSFWLGIMLIMAFAVSLGWLPSGGFVNFSDAPLENL
HHHHHCCCCHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHCCCCCCCEECCCCCCHHHH
RYTLLPSLVLGTAAAAIIMRHTRNSMLSVLKQDYIRTARAKGLKERIVIIRHALRNGLIP
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHCCCEE
IVTTGTLHLGELLSGAVLTEQVFGIPGFGKMIVDGVFSRDYAVVQAVILCSAAIFLILSL
EEECCHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHH
LADILYVKLSPRLQA
HHHHHHHHCCCCCCC
>Mature Secondary Structure 
AMLNFIFRRVLAAIPTLLILSVFVFLLLKLLPGDPALALAGEDRDPAVIESIRVKYGLD
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEECCCCCCHHHHHHHHHHHCCC
QPLPVQYFKWLGDILQGDFGVSIRTKMSIGEMLAQRLPVTLQLSLQAMLIAIIIGIPAGV
CCCCHHHHHHHHHHHCCCCCCEEEHHHHHHHHHHHHCCEEEEHHHHHHHHHHHHHCCHHH
YAAIRRGSYVDVAVSTVGLAGLSVPSFWLGIMLIMAFAVSLGWLPSGGFVNFSDAPLENL
HHHHHCCCCHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHCCCCCCCEECCCCCCHHHH
RYTLLPSLVLGTAAAAIIMRHTRNSMLSVLKQDYIRTARAKGLKERIVIIRHALRNGLIP
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHCCCEE
IVTTGTLHLGELLSGAVLTEQVFGIPGFGKMIVDGVFSRDYAVVQAVILCSAAIFLILSL
EEECCHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHH
LADILYVKLSPRLQA
HHHHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]