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The map label for this gene is pfpI [H]

Identifier: 110633837

GI number: 110633837

Start: 1581135

End: 1581695

Strand: Reverse

Name: pfpI [H]

Synonym: Meso_1484

Alternate gene names: 110633837

Gene position: 1581695-1581135 (Counterclockwise)

Preceding gene: 110633839

Following gene: 110633836

Centisome position: 35.85

GC content: 58.65

Gene sequence:

>561_bases
ATGCAGGACATCTCTGGAAAAAGGGTGGCAATTCTCGCAACCCATGGCTTCGAGCAGTCTGAACTTGAGGTCCCTCTCAA
CAAGCTGCGGCAGGCGGGCGCGGAGGTTCACGTAATCTCGCTCGAGCCCGGCGAGATCAAGGGATGGGACGAGAAGGATT
GGGGGCGTCCGGTTAAAGTCGACAAGACTTTGGACGAGGCACGGCCGGAAGACTATGATGCCCTCGTCCTGCCCGGCGGA
CAGATCAATCCCGATCTTCTGCGCGTGGAGAAGGCAGCTCTCGATTTCATCAAGAGCTTCTGGAATGACAGCAAGGTCAT
CGGCGCCGTCTGCCATGCTCCCTGGTTGCTCGTTGAGACCGGGATTTTAAAGGGCCGCCGCGTCACTTCTTACCATTCGA
TCAAGACGGACGTCATCAATGCCGGCGGTAAATGGGAGGACTCGCAGGTCGTCACCGATCAGGGTCTCGTTACCAGCCGC
AATCCGGGTGACCTTGACGCATTCTGCGACAAGCTCGCTGAGGAAATACGGGAAGGAAGGCACCAGCGCCGCGCCGCCTA
G

Upstream 100 bases:

>100_bases
GTTCCAGTGCCACGGTCCCTTTTCCCCCGCCCGAAAGCGGAACACCTCTCTAACTCCCCGGTTTGGCAGGTAGTCCCCAA
AGAGATAGATGGAGCGAGCG

Downstream 100 bases:

>100_bases
GGCTTCAATAAGGCGCGCCGATCCTCCCGGTTGACCGCGCCGACCCGCCCGCGCCCTCTGGCCGGGTGGGTTTTACTTTG
AGCAAAATTTTGAAAGAAAA

Product: PfpI family intracellular peptidase

Products: NA

Alternate protein names: Intracellular protease I [H]

Number of amino acids: Translated: 186; Mature: 186

Protein sequence:

>186_residues
MQDISGKRVAILATHGFEQSELEVPLNKLRQAGAEVHVISLEPGEIKGWDEKDWGRPVKVDKTLDEARPEDYDALVLPGG
QINPDLLRVEKAALDFIKSFWNDSKVIGAVCHAPWLLVETGILKGRRVTSYHSIKTDVINAGGKWEDSQVVTDQGLVTSR
NPGDLDAFCDKLAEEIREGRHQRRAA

Sequences:

>Translated_186_residues
MQDISGKRVAILATHGFEQSELEVPLNKLRQAGAEVHVISLEPGEIKGWDEKDWGRPVKVDKTLDEARPEDYDALVLPGG
QINPDLLRVEKAALDFIKSFWNDSKVIGAVCHAPWLLVETGILKGRRVTSYHSIKTDVINAGGKWEDSQVVTDQGLVTSR
NPGDLDAFCDKLAEEIREGRHQRRAA
>Mature_186_residues
MQDISGKRVAILATHGFEQSELEVPLNKLRQAGAEVHVISLEPGEIKGWDEKDWGRPVKVDKTLDEARPEDYDALVLPGG
QINPDLLRVEKAALDFIKSFWNDSKVIGAVCHAPWLLVETGILKGRRVTSYHSIKTDVINAGGKWEDSQVVTDQGLVTSR
NPGDLDAFCDKLAEEIREGRHQRRAA

Specific function: Unknown

COG id: COG0693

COG function: function code R; Putative intracellular protease/amidase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 PfpI endopeptidase domain [H]

Homologues:

Organism=Homo sapiens, GI183227678, Length=177, Percent_Identity=29.3785310734463, Blast_Score=72, Evalue=2e-13,
Organism=Homo sapiens, GI31543380, Length=177, Percent_Identity=29.3785310734463, Blast_Score=72, Evalue=2e-13,
Organism=Escherichia coli, GI87082219, Length=164, Percent_Identity=42.0731707317073, Blast_Score=126, Evalue=7e-31,
Organism=Caenorhabditis elegans, GI17531319, Length=178, Percent_Identity=31.4606741573034, Blast_Score=72, Evalue=2e-13,
Organism=Drosophila melanogaster, GI28571932, Length=172, Percent_Identity=31.3953488372093, Blast_Score=87, Evalue=8e-18,
Organism=Drosophila melanogaster, GI24653499, Length=178, Percent_Identity=30.8988764044944, Blast_Score=72, Evalue=2e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006286
- InterPro:   IPR002818 [H]

Pfam domain/function: PF01965 DJ-1_PfpI [H]

EC number: NA

Molecular weight: Translated: 20676; Mature: 20676

Theoretical pI: Translated: 5.36; Mature: 5.36

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
0.5 %Met     (Translated Protein)
1.6 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
0.5 %Met     (Mature Protein)
1.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQDISGKRVAILATHGFEQSELEVPLNKLRQAGAEVHVISLEPGEIKGWDEKDWGRPVKV
CCCCCCCEEEEEEECCCCCCHHHCCHHHHHHCCCEEEEEEECCCCCCCCCCCCCCCCEEE
DKTLDEARPEDYDALVLPGGQINPDLLRVEKAALDFIKSFWNDSKVIGAVCHAPWLLVET
CCCHHHCCCCCCCEEEECCCCCCHHHHHHHHHHHHHHHHHHCCCHHHHHHHHCCCCEEHH
GILKGRRVTSYHSIKTDVINAGGKWEDSQVVTDQGLVTSRNPGDLDAFCDKLAEEIREGR
HHCCCCEECHHHHHHHHEECCCCCCCCCEEECCCCEEECCCCCCHHHHHHHHHHHHHHHH
HQRRAA
HHHCCC
>Mature Secondary Structure
MQDISGKRVAILATHGFEQSELEVPLNKLRQAGAEVHVISLEPGEIKGWDEKDWGRPVKV
CCCCCCCEEEEEEECCCCCCHHHCCHHHHHHCCCEEEEEEECCCCCCCCCCCCCCCCEEE
DKTLDEARPEDYDALVLPGGQINPDLLRVEKAALDFIKSFWNDSKVIGAVCHAPWLLVET
CCCHHHCCCCCCCEEEECCCCCCHHHHHHHHHHHHHHHHHHCCCHHHHHHHHCCCCEEHH
GILKGRRVTSYHSIKTDVINAGGKWEDSQVVTDQGLVTSRNPGDLDAFCDKLAEEIREGR
HHCCCCEECHHHHHHHHEECCCCCCCCCEEECCCCEEECCCCCCHHHHHHHHHHHHHHHH
HQRRAA
HHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA