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The map label for this gene is slyD [C]

Identifier: 110633824

GI number: 110633824

Start: 1569674

End: 1570132

Strand: Reverse

Name: slyD [C]

Synonym: Meso_1471

Alternate gene names: 110633824

Gene position: 1570132-1569674 (Counterclockwise)

Preceding gene: 110633825

Following gene: 110633821

Centisome position: 35.58

GC content: 61.44

Gene sequence:

>459_bases
ATGAGACAAGCCAGAGCGGGCGATGTCGTACGCGTCCATTACCGGGGACGCCTCACCGACGGCACCGAGTTCGATTCCTC
CGACGGTCGCGAGCCCCTGGAATTCCAGGTCGGCGGCGGTCAGGTCATTGCCGGTTTCGAAAAGCAGGTGGAAGGCATGG
AGGTCGGCGAAACATCGACCGTGACCATTCCCGCCAATCAGGCCTATGGCGAGCGCGACGAACGGCAAGTGCAATCCGTG
CCGCGCAACACGATGCCTGACAATCTGGACCTGCAGGTCGGCACGCGGCTGACCGCCACCACGCGGGACGGCAAGCAGAT
ACCGCTTACCGTAACCGACGTGAATGACGAGCAGGTGATCGTCGATGCCAATCATCCGCTGGCGGGACAAGATCTCGTCT
TCGATATCGAACTGGTCGAGATCGTCGGTTCCGAGCCCGGCCTGAAATTCGGGCAATAG

Upstream 100 bases:

>100_bases
CTAGCATGCCCTACCCTTGGCCTTAGTGGCGGCGATCCATGGCCCGCCGCTTGGCGCCTGAGCGCGAACTGGATCGAAAT
CGGTAAAAAGGGAGAAATCC

Downstream 100 bases:

>100_bases
GAGATCAGGGAAAAGGAAAGTAGGCCAGAAGGCGGCTTTACCGCCTATTTCGGCTATTCCCTCTCCGGCAAAGCGGGACT
AACCGAACAGGGCGTCGCCC

Product: peptidylprolyl isomerase, FKBP-type

Products: NA

Alternate protein names: PPIase; MtFK; Rotamase [H]

Number of amino acids: Translated: 152; Mature: 152

Protein sequence:

>152_residues
MRQARAGDVVRVHYRGRLTDGTEFDSSDGREPLEFQVGGGQVIAGFEKQVEGMEVGETSTVTIPANQAYGERDERQVQSV
PRNTMPDNLDLQVGTRLTATTRDGKQIPLTVTDVNDEQVIVDANHPLAGQDLVFDIELVEIVGSEPGLKFGQ

Sequences:

>Translated_152_residues
MRQARAGDVVRVHYRGRLTDGTEFDSSDGREPLEFQVGGGQVIAGFEKQVEGMEVGETSTVTIPANQAYGERDERQVQSV
PRNTMPDNLDLQVGTRLTATTRDGKQIPLTVTDVNDEQVIVDANHPLAGQDLVFDIELVEIVGSEPGLKFGQ
>Mature_152_residues
MRQARAGDVVRVHYRGRLTDGTEFDSSDGREPLEFQVGGGQVIAGFEKQVEGMEVGETSTVTIPANQAYGERDERQVQSV
PRNTMPDNLDLQVGTRLTATTRDGKQIPLTVTDVNDEQVIVDANHPLAGQDLVFDIELVEIVGSEPGLKFGQ

Specific function: PPIases accelerate the folding of proteins [H]

COG id: COG1047

COG function: function code O; FKBP-type peptidyl-prolyl cis-trans isomerases 2

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 PPIase FKBP-type domain [H]

Homologues:

Organism=Homo sapiens, GI206725530, Length=71, Percent_Identity=47.887323943662, Blast_Score=70, Evalue=8e-13,
Organism=Homo sapiens, GI17149844, Length=71, Percent_Identity=47.887323943662, Blast_Score=70, Evalue=8e-13,
Organism=Homo sapiens, GI17149842, Length=71, Percent_Identity=47.887323943662, Blast_Score=70, Evalue=8e-13,
Organism=Escherichia coli, GI1789748, Length=133, Percent_Identity=43.609022556391, Blast_Score=103, Evalue=4e-24,
Organism=Escherichia coli, GI1786211, Length=138, Percent_Identity=31.1594202898551, Blast_Score=83, Evalue=7e-18,
Organism=Caenorhabditis elegans, GI17540882, Length=108, Percent_Identity=38.8888888888889, Blast_Score=70, Evalue=4e-13,
Organism=Saccharomyces cerevisiae, GI6320727, Length=74, Percent_Identity=48.6486486486487, Blast_Score=68, Evalue=6e-13,
Organism=Saccharomyces cerevisiae, GI6324194, Length=69, Percent_Identity=43.4782608695652, Blast_Score=62, Evalue=4e-11,
Organism=Drosophila melanogaster, GI24583150, Length=67, Percent_Identity=50.7462686567164, Blast_Score=69, Evalue=1e-12,
Organism=Drosophila melanogaster, GI21356629, Length=64, Percent_Identity=53.125, Blast_Score=69, Evalue=1e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001179 [H]

Pfam domain/function: PF00254 FKBP_C [H]

EC number: =5.2.1.8 [H]

Molecular weight: Translated: 16596; Mature: 16596

Theoretical pI: Translated: 4.22; Mature: 4.22

Prosite motif: PS50059 FKBP_PPIASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
2.0 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
2.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRQARAGDVVRVHYRGRLTDGTEFDSSDGREPLEFQVGGGQVIAGFEKQVEGMEVGETST
CCCCCCCCEEEEEEECEECCCCCCCCCCCCCCEEEEECCCEEEECHHHCCCCEECCCCEE
VTIPANQAYGERDERQVQSVPRNTMPDNLDLQVGTRLTATTRDGKQIPLTVTDVNDEQVI
EEEECCCCCCCCHHHHHHHCCCCCCCCCCEEEECCEEEEECCCCCCCCEEEEECCCCEEE
VDANHPLAGQDLVFDIELVEIVGSEPGLKFGQ
EECCCCCCCCCEEEEEEEEEEECCCCCCCCCC
>Mature Secondary Structure
MRQARAGDVVRVHYRGRLTDGTEFDSSDGREPLEFQVGGGQVIAGFEKQVEGMEVGETST
CCCCCCCCEEEEEEECEECCCCCCCCCCCCCCEEEEECCCEEEECHHHCCCCEECCCCEE
VTIPANQAYGERDERQVQSVPRNTMPDNLDLQVGTRLTATTRDGKQIPLTVTDVNDEQVI
EEEECCCCCCCCHHHHHHHCCCCCCCCCCEEEECCEEEEECCCCCCCCEEEEECCCCEEE
VDANHPLAGQDLVFDIELVEIVGSEPGLKFGQ
EECCCCCCCCCEEEEEEEEEEECCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9440528 [H]