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The map label for this gene is 110633785

Identifier: 110633785

GI number: 110633785

Start: 1529645

End: 1530190

Strand: Direct

Name: 110633785

Synonym: Meso_1432

Alternate gene names: NA

Gene position: 1529645-1530190 (Clockwise)

Preceding gene: 110633783

Following gene: 110633794

Centisome position: 34.67

GC content: 60.62

Gene sequence:

>546_bases
ATGTCTCTTACCGCTTTCTTTTCACGTCCCTCTGTCGTTGTCGCGAAAGATCTGATCGGAGCGAATTTCTTCGTCGGGTC
CGCGGGCGGCATTATCGTCGAGACCGAGGCCTATGATCGAGAAGAGCCGGCCTCCCACAGCTTCCGCGGTCCTACCGCCC
GAAACAGGTCGATGTTCGGCCCGCCTGCGCATGCCTACGTCTACCGTTCCTATGGTATTCATTGGTGTTTGAACTTCGTC
TGCCTGCCGGGCAGCGGGGTCCTCATCCGTGCCCTGGAGCCCACCGCGGGCATCGAACTGATGCAGGAGCGCCGCCGGAC
GATTTCCCTGAAACAGCTCTGTTCCGGTCCGGGACGGGTAGGGGAGGCACTCGGCATCGACCGGTCTCTTGACGGGCGCG
GTCTCGATCAACCGCCCTTCAGACTGGATCTGTCGAACGCAAAAGCATGCGCCATAAGCGGCACGCGCATCGGCATCACG
CGCGCCGCCGAGCTAGAGTGGAGGTTCGGGTTGGAAGGCTCAATCTATGTGAGCCGCAAATTCTAA

Upstream 100 bases:

>100_bases
GCTTTCCAATAGGGCAGGCTAACAGCGGCTTCCGCACTCCGGCCTTGACCCCTCGCTTCCATCCTGCAATTCAGACAGTC
TGGATACCCTCTTCTTGATC

Downstream 100 bases:

>100_bases
CGGCGCGCTTTCTGGCGCGGCCAACATGCGGAAATTGCCCTTACGCCCCCTCAACACTCTCAAAGCCCTCGAAAGCCGGC
GGGCCCTTATATAGCCCTTT

Product: 3-methyladenine DNA glycosylase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 181; Mature: 180

Protein sequence:

>181_residues
MSLTAFFSRPSVVVAKDLIGANFFVGSAGGIIVETEAYDREEPASHSFRGPTARNRSMFGPPAHAYVYRSYGIHWCLNFV
CLPGSGVLIRALEPTAGIELMQERRRTISLKQLCSGPGRVGEALGIDRSLDGRGLDQPPFRLDLSNAKACAISGTRIGIT
RAAELEWRFGLEGSIYVSRKF

Sequences:

>Translated_181_residues
MSLTAFFSRPSVVVAKDLIGANFFVGSAGGIIVETEAYDREEPASHSFRGPTARNRSMFGPPAHAYVYRSYGIHWCLNFV
CLPGSGVLIRALEPTAGIELMQERRRTISLKQLCSGPGRVGEALGIDRSLDGRGLDQPPFRLDLSNAKACAISGTRIGIT
RAAELEWRFGLEGSIYVSRKF
>Mature_180_residues
SLTAFFSRPSVVVAKDLIGANFFVGSAGGIIVETEAYDREEPASHSFRGPTARNRSMFGPPAHAYVYRSYGIHWCLNFVC
LPGSGVLIRALEPTAGIELMQERRRTISLKQLCSGPGRVGEALGIDRSLDGRGLDQPPFRLDLSNAKACAISGTRIGITR
AAELEWRFGLEGSIYVSRKF

Specific function: Unknown

COG id: COG2094

COG function: function code L; 3-methyladenine DNA glycosylase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the DNA glycosylase MPG family

Homologues:

Organism=Homo sapiens, GI62632769, Length=149, Percent_Identity=39.5973154362416, Blast_Score=90, Evalue=1e-18,
Organism=Homo sapiens, GI62632771, Length=149, Percent_Identity=39.5973154362416, Blast_Score=89, Evalue=1e-18,
Organism=Homo sapiens, GI62632765, Length=149, Percent_Identity=39.5973154362416, Blast_Score=89, Evalue=2e-18,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): 3MGH_MESSB (Q11IE7)

Other databases:

- EMBL:   CP000390
- RefSeq:   YP_673993.1
- ProteinModelPortal:   Q11IE7
- SMR:   Q11IE7
- STRING:   Q11IE7
- GeneID:   4179393
- GenomeReviews:   CP000390_GR
- KEGG:   mes:Meso_1432
- NMPDR:   fig|266779.1.peg.2161
- eggNOG:   COG2094
- HOGENOM:   HBG664239
- OMA:   ACHAYRR
- ProtClustDB:   PRK00802
- BioCyc:   MSP266779:MESO_1432-MONOMER
- HAMAP:   MF_00527
- InterPro:   IPR011034
- InterPro:   IPR003180
- Gene3D:   G3DSA:3.10.300.10
- PANTHER:   PTHR10429
- TIGRFAMs:   TIGR00567

Pfam domain/function: PF02245 Pur_DNA_glyco; SSF50486 FMT_C_like

EC number: 3.2.2.-

Molecular weight: Translated: 19753; Mature: 19622

Theoretical pI: Translated: 9.27; Mature: 9.27

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.2 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
3.9 %Cys+Met (Translated Protein)
2.2 %Cys     (Mature Protein)
1.1 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSLTAFFSRPSVVVAKDLIGANFFVGSAGGIIVETEAYDREEPASHSFRGPTARNRSMFG
CCEEECCCCCCEEEEHHHCCCEEEEECCCCEEEEECCCCCCCCCCCCCCCCCCCCCCCCC
PPAHAYVYRSYGIHWCLNFVCLPGSGVLIRALEPTAGIELMQERRRTISLKQLCSGPGRV
CCCCEEEEECCCCEEEEEEEEECCCCEEEEEECCCCCHHHHHHHHHHCCHHHHHCCCCCC
GEALGIDRSLDGRGLDQPPFRLDLSNAKACAISGTRIGITRAAELEWRFGLEGSIYVSRK
CHHHCCCCCCCCCCCCCCCEEEECCCCCEEEECCCEEEEEEEEEEEEEECCCCEEEEEEC
F
C
>Mature Secondary Structure 
SLTAFFSRPSVVVAKDLIGANFFVGSAGGIIVETEAYDREEPASHSFRGPTARNRSMFG
CEEECCCCCCEEEEHHHCCCEEEEECCCCEEEEECCCCCCCCCCCCCCCCCCCCCCCCC
PPAHAYVYRSYGIHWCLNFVCLPGSGVLIRALEPTAGIELMQERRRTISLKQLCSGPGRV
CCCCEEEEECCCCEEEEEEEEECCCCEEEEEECCCCCHHHHHHHHHHCCHHHHHCCCCCC
GEALGIDRSLDGRGLDQPPFRLDLSNAKACAISGTRIGITRAAELEWRFGLEGSIYVSRK
CHHHCCCCCCCCCCCCCCCEEEECCCCCEEEECCCEEEEEEEEEEEEEECCCCEEEEEEC
F
C

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA