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The map label for this gene is sseA [H]

Identifier: 110633779

GI number: 110633779

Start: 1524752

End: 1525597

Strand: Direct

Name: sseA [H]

Synonym: Meso_1426

Alternate gene names: 110633779

Gene position: 1524752-1525597 (Clockwise)

Preceding gene: 110633777

Following gene: 110633780

Centisome position: 34.56

GC content: 64.42

Gene sequence:

>846_bases
ATGAGTGAAAAGAGCCCCTTTGTCGTTTCGCCCGATTGGCTGCAGGAACGTCTCGGCAGTCCGGGCCTGTCAATCGTGGA
CGGGTCCTGGTATTTCCCCGGCCGCGACGCGCGGGCTGAATATGAGGCGTCGCATATTCCCGGCGCGGTGTTCTTCGATC
ACGACCTCGTCGTCGACACGGATTCCGATCTGCCCCATGCGCTCCCCGACCCGCTGACCTTCGAGCGCCATGCGAGTTCG
ATGGGCATCTCAAAGGACGACACCATCGTCGTCTATGATGGGCCGGGCCTCTTGGCCGCCCCGCGCGCCTGGTGGCTTTT
CCGGGTCATGGGCGCAAAGAAGGTCTTCGTGCTCGACGGCGGCTTTGAGCGCTGGCGGTCGGAGGGGCGCCCCGTGACGG
GCGAGAGGACGAAAATCGCTCCATCGGCCTTTGTTTCTGAATTCGATGCGAGCCGGGTGGTTCCTTTCGAGGAGATGCGG
CGCATCGTCGAGCGAGAGGAAGCGCAGATTGCCGATGCCCGCTCGGCGGGCCGTTTTGCCGGCACCGAGCCGGAGCCGCG
CCTCGGCCTTCGCGGCGGCCATATGCCGGGAGCCGTGAGTGTTCCTGCCGCCTCCCTATCGGAGAACGGAGAGCTTCTGC
CGCTTGATCGGCTCCGGGAAAAGCTGGAGGCCGCGGGCATTGATCTGGAAAGGCCAGTCGTGACCTCCTGTGGCTCCGGC
GTAACGGCGGCGGTGATCACGCTAGCGCTCGAATCCCTCGGCCATAAGGACAACCGCCTTTATGACGGCTCCTGGAGCGA
GTGGGGAAGGCATCAGGATACGCCGGTGGTGACGGGGGACAAATGA

Upstream 100 bases:

>100_bases
TTTGCCGGAGCAACGTTCCTCGGCATCATCGATCGTTGCGACCTCATCTTTTCTTTCCGCGCAATTGGGTGGATGATCAC
CCTAGCTTCAGGTGTGTAGC

Downstream 100 bases:

>100_bases
GCGGAAAGGAACCCCTCTCCAAAGCGCGTTCCCTGGCGGCAGTGGTGACGCACCTGCGGATGGATGCGCCCCCGCCCGGC
CATCCGCTTTTCCCTTCGGG

Product: rhodanese-like protein

Products: NA

Alternate protein names: MST; Rhodanese-like protein [H]

Number of amino acids: Translated: 281; Mature: 280

Protein sequence:

>281_residues
MSEKSPFVVSPDWLQERLGSPGLSIVDGSWYFPGRDARAEYEASHIPGAVFFDHDLVVDTDSDLPHALPDPLTFERHASS
MGISKDDTIVVYDGPGLLAAPRAWWLFRVMGAKKVFVLDGGFERWRSEGRPVTGERTKIAPSAFVSEFDASRVVPFEEMR
RIVEREEAQIADARSAGRFAGTEPEPRLGLRGGHMPGAVSVPAASLSENGELLPLDRLREKLEAAGIDLERPVVTSCGSG
VTAAVITLALESLGHKDNRLYDGSWSEWGRHQDTPVVTGDK

Sequences:

>Translated_281_residues
MSEKSPFVVSPDWLQERLGSPGLSIVDGSWYFPGRDARAEYEASHIPGAVFFDHDLVVDTDSDLPHALPDPLTFERHASS
MGISKDDTIVVYDGPGLLAAPRAWWLFRVMGAKKVFVLDGGFERWRSEGRPVTGERTKIAPSAFVSEFDASRVVPFEEMR
RIVEREEAQIADARSAGRFAGTEPEPRLGLRGGHMPGAVSVPAASLSENGELLPLDRLREKLEAAGIDLERPVVTSCGSG
VTAAVITLALESLGHKDNRLYDGSWSEWGRHQDTPVVTGDK
>Mature_280_residues
SEKSPFVVSPDWLQERLGSPGLSIVDGSWYFPGRDARAEYEASHIPGAVFFDHDLVVDTDSDLPHALPDPLTFERHASSM
GISKDDTIVVYDGPGLLAAPRAWWLFRVMGAKKVFVLDGGFERWRSEGRPVTGERTKIAPSAFVSEFDASRVVPFEEMRR
IVEREEAQIADARSAGRFAGTEPEPRLGLRGGHMPGAVSVPAASLSENGELLPLDRLREKLEAAGIDLERPVVTSCGSGV
TAAVITLALESLGHKDNRLYDGSWSEWGRHQDTPVVTGDK

Specific function: Transfers a sulfur ion to cyanide or to other thiol compounds. Also has weak rhodanese activity. Its participation in detoxification of cyanide may be small. May be involved in the enhancement of serine sensitivity [H]

COG id: COG2897

COG function: function code P; Rhodanese-related sulfurtransferase

Gene ontology:

Cell location: Cytoplasm (Probable) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 2 rhodanese domains [H]

Homologues:

Organism=Homo sapiens, GI17402865, Length=272, Percent_Identity=42.6470588235294, Blast_Score=208, Evalue=4e-54,
Organism=Homo sapiens, GI194473668, Length=270, Percent_Identity=39.6296296296296, Blast_Score=208, Evalue=5e-54,
Organism=Homo sapiens, GI61835204, Length=270, Percent_Identity=39.6296296296296, Blast_Score=207, Evalue=6e-54,
Organism=Homo sapiens, GI194473681, Length=270, Percent_Identity=39.6296296296296, Blast_Score=207, Evalue=6e-54,
Organism=Escherichia coli, GI87082121, Length=275, Percent_Identity=40.7272727272727, Blast_Score=211, Evalue=5e-56,
Organism=Escherichia coli, GI87081967, Length=294, Percent_Identity=26.8707482993197, Blast_Score=84, Evalue=9e-18,
Organism=Caenorhabditis elegans, GI17561888, Length=290, Percent_Identity=26.8965517241379, Blast_Score=109, Evalue=1e-24,
Organism=Caenorhabditis elegans, GI71997283, Length=291, Percent_Identity=25.7731958762887, Blast_Score=105, Evalue=2e-23,
Organism=Caenorhabditis elegans, GI17559150, Length=250, Percent_Identity=26.8, Blast_Score=96, Evalue=2e-20,
Organism=Caenorhabditis elegans, GI115534702, Length=243, Percent_Identity=26.3374485596708, Blast_Score=93, Evalue=1e-19,
Organism=Caenorhabditis elegans, GI17543836, Length=292, Percent_Identity=26.7123287671233, Blast_Score=86, Evalue=2e-17,
Organism=Caenorhabditis elegans, GI17543838, Length=292, Percent_Identity=26.7123287671233, Blast_Score=86, Evalue=2e-17,
Organism=Caenorhabditis elegans, GI17533113, Length=143, Percent_Identity=30.7692307692308, Blast_Score=68, Evalue=6e-12,
Organism=Saccharomyces cerevisiae, GI6324825, Length=266, Percent_Identity=35.3383458646617, Blast_Score=157, Evalue=2e-39,

Paralogues:

None

Copy number: 20 Molecules/Cell In: Stationary Phase, Rich Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001763
- InterPro:   IPR001307 [H]

Pfam domain/function: PF00581 Rhodanese [H]

EC number: =2.8.1.2 [H]

Molecular weight: Translated: 30723; Mature: 30592

Theoretical pI: Translated: 4.81; Mature: 4.81

Prosite motif: PS00380 RHODANESE_1 ; PS50206 RHODANESE_3

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
2.1 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
1.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSEKSPFVVSPDWLQERLGSPGLSIVDGSWYFPGRDARAEYEASHIPGAVFFDHDLVVDT
CCCCCCEEECHHHHHHHHCCCCCEEECCCEECCCCCCCCCCHHHCCCEEEEECCEEEEEC
DSDLPHALPDPLTFERHASSMGISKDDTIVVYDGPGLLAAPRAWWLFRVMGAKKVFVLDG
CCCCCCCCCCCCCHHHHHHHCCCCCCCEEEEECCCCCEECCHHHHHHHHHCCCEEEEEEC
GFERWRSEGRPVTGERTKIAPSAFVSEFDASRVVPFEEMRRIVEREEAQIADARSAGRFA
CHHHHHHCCCCCCCCCCCCCHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCC
GTEPEPRLGLRGGHMPGAVSVPAASLSENGELLPLDRLREKLEAAGIDLERPVVTSCGSG
CCCCCCCCCCCCCCCCCCCCCCCHHHCCCCCEECHHHHHHHHHHCCCCCCCCHHHHCCCC
VTAAVITLALESLGHKDNRLYDGSWSEWGRHQDTPVVTGDK
HHHHHHHHHHHHHCCCCCEEECCCHHHHCCCCCCCEECCCC
>Mature Secondary Structure 
SEKSPFVVSPDWLQERLGSPGLSIVDGSWYFPGRDARAEYEASHIPGAVFFDHDLVVDT
CCCCCEEECHHHHHHHHCCCCCEEECCCEECCCCCCCCCCHHHCCCEEEEECCEEEEEC
DSDLPHALPDPLTFERHASSMGISKDDTIVVYDGPGLLAAPRAWWLFRVMGAKKVFVLDG
CCCCCCCCCCCCCHHHHHHHCCCCCCCEEEEECCCCCEECCHHHHHHHHHCCCEEEEEEC
GFERWRSEGRPVTGERTKIAPSAFVSEFDASRVVPFEEMRRIVEREEAQIADARSAGRFA
CHHHHHHCCCCCCCCCCCCCHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCC
GTEPEPRLGLRGGHMPGAVSVPAASLSENGELLPLDRLREKLEAAGIDLERPVVTSCGSG
CCCCCCCCCCCCCCCCCCCCCCCHHHCCCCCEECHHHHHHHHHHCCCCCCCCHHHHCCCC
VTAAVITLALESLGHKDNRLYDGSWSEWGRHQDTPVVTGDK
HHHHHHHHHHHHHCCCCCEEECCCHHHHCCCCCCCEECCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]