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The map label for this gene is aidB [H]

Identifier: 110633713

GI number: 110633713

Start: 1453336

End: 1454967

Strand: Direct

Name: aidB [H]

Synonym: Meso_1360

Alternate gene names: 110633713

Gene position: 1453336-1454967 (Clockwise)

Preceding gene: 110633708

Following gene: 110633715

Centisome position: 32.94

GC content: 64.34

Gene sequence:

>1632_bases
ATGAAGAATGAAGAGGTGCTGAACCAGCCGCCGCCGATAAGCGGCACGAACGCGTGGCGCGGCGATCCCTTGCTGGTGCA
GCTTTGTGAGCGTTTCTCCGAGCCCGTCCGAAAGGACGTTGAGCAGCTCGGCCGTTTCGTGCGGACGCAAGAAGCGCAAG
AGCTGGCGCGGCTCGCAAACACCGAGCTCCCCGTTCTCAAGACCCATGACCGATATGGCTTCCGCGTGGATCAGGTGGAA
TATCATCCCGCCTATCACGCCTTGATGCGGCGGTCCGCAAGTGCGGGCCTCCATTCCTCCATCTGGGAGGACGGTGAGGA
CGAGAAGGGCCAGCGTCATCAGGCGCGGGCAGCGCGATTCTATCTGACGGCGCAGCTGGAATGCGGCCATCTGTGCCCGA
TGACCATGACGAGTGCGGCTCTCGCCGCGCTCATGTCAAACCCGGCGCTTTTCCGCGCCTGGGCGCCACGTGTGATCGCG
CGCAAATATGACAACGCTAACAGGCCCGCCGCCCAGAAGCAGGGCGTCACGCTCGGCATGGGCATGACGGAAAAGCAGGG
CGGCACCGATGTGCGCGCGAATACGACCAGAGCCGAACCGGCCGGAGAAGGGCTTTATCGTCTCAACGGCCACAAGTGGT
TCATGTCCGCGCCCATGAGCGACGGATTCCTGGTTCTGGCACAGGCGGAGGAGGGCCTTTCCTGCTTTCTGCTGCCGAGG
GTCACCGATGACGGCGCGACCAACGGCTTTCGTTTTCAAAGGCTGAAAGACAAGCTCGGCAACCGTTCGAACGCCTCCTC
GGAGGTCGAATTCGAGGGAGCGCTCGGCTATCTCGTCGGCGAGCCCGGCGCGGGCATACGCACCATCATGGACATGGTCA
CGCTGACGCGGCTCGACTGCGCGCTTGCCTCTTCAGGGCTGATGCGGGCGGCGCTCGCAGAGGCGGTGCATCACGCGCGG
CACCGCAGCGTTTTCGGCAAGGCGCTCTTCGAGCAGCCGTTGATGAACCGGGTGTTGGCCGATCTCGCGCTCGATGTGGC
GGCCGCCACCGCGCTTGCGTTCCGGCTGGCGCGCTCCTTCGATGAGGCGGCGAACGGCCGTGCCGAGGCCGCCTATGCCC
GCGTGATGACGCCGGTCACAAAATACTGGGTGTGCAAGATCGCGCCCGCGGTGATCTATGAGGCCATGGAATGCCTGGGC
GGCAACGGCTATGTGGAGGAGGCGCCACTCGCCCGCTATTACCGCGAAGCACCGGTGAATGCGATCTGGGAAGGTTCGGG
CAATGTGATGGCGCTGGACGTGCTGCGTGTCTTGTCACGCAATGCAGGGCTGTTCGACGACGTTCTTCAGGGAATGGCCG
CGGATCTAGGCCCGGCGGGAAGCGGCACGGTCGAAGTGCTCTCGGCGGCCATGCGCGTGTGCGAAAGCGACGAAGGGGCA
GGGCGGATCCTGACGGAACAACTGGCCCTGGCTGCGGCAGCGGCCGAGCTGAAGCGGCTCGGAGCGGGGCAGGTGGCTGA
CGCCTTTATAGAGACACGACTTGCCGGCCAATGGCGCGGCACCTACGGAATGCTCGATGCGCGATATGATGCGGTAGCCA
TCCTGGATATGCTCTACCCCGAGGCGATGTGA

Upstream 100 bases:

>100_bases
GGAAAGAAAAAGAGATAAGGCATTCTGTTGACATGGACCATATATCAGAATCGGCCGTTTCTTTCATAACATCCGGGTTC
GCCGCCTCGGAGGAGGTGTC

Downstream 100 bases:

>100_bases
GCGCCTTGGCTTCTACCCGCCGGGGTCCGCACGCAAGGCCTGAAGGCGGTCGAGCGCGCCCTGCAGGATGAAGGCCGCCG
CCGCTGAATCGATGCGTTGC

Product: acyl-CoA dehydrogenase-like

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 543; Mature: 543

Protein sequence:

>543_residues
MKNEEVLNQPPPISGTNAWRGDPLLVQLCERFSEPVRKDVEQLGRFVRTQEAQELARLANTELPVLKTHDRYGFRVDQVE
YHPAYHALMRRSASAGLHSSIWEDGEDEKGQRHQARAARFYLTAQLECGHLCPMTMTSAALAALMSNPALFRAWAPRVIA
RKYDNANRPAAQKQGVTLGMGMTEKQGGTDVRANTTRAEPAGEGLYRLNGHKWFMSAPMSDGFLVLAQAEEGLSCFLLPR
VTDDGATNGFRFQRLKDKLGNRSNASSEVEFEGALGYLVGEPGAGIRTIMDMVTLTRLDCALASSGLMRAALAEAVHHAR
HRSVFGKALFEQPLMNRVLADLALDVAAATALAFRLARSFDEAANGRAEAAYARVMTPVTKYWVCKIAPAVIYEAMECLG
GNGYVEEAPLARYYREAPVNAIWEGSGNVMALDVLRVLSRNAGLFDDVLQGMAADLGPAGSGTVEVLSAAMRVCESDEGA
GRILTEQLALAAAAAELKRLGAGQVADAFIETRLAGQWRGTYGMLDARYDAVAILDMLYPEAM

Sequences:

>Translated_543_residues
MKNEEVLNQPPPISGTNAWRGDPLLVQLCERFSEPVRKDVEQLGRFVRTQEAQELARLANTELPVLKTHDRYGFRVDQVE
YHPAYHALMRRSASAGLHSSIWEDGEDEKGQRHQARAARFYLTAQLECGHLCPMTMTSAALAALMSNPALFRAWAPRVIA
RKYDNANRPAAQKQGVTLGMGMTEKQGGTDVRANTTRAEPAGEGLYRLNGHKWFMSAPMSDGFLVLAQAEEGLSCFLLPR
VTDDGATNGFRFQRLKDKLGNRSNASSEVEFEGALGYLVGEPGAGIRTIMDMVTLTRLDCALASSGLMRAALAEAVHHAR
HRSVFGKALFEQPLMNRVLADLALDVAAATALAFRLARSFDEAANGRAEAAYARVMTPVTKYWVCKIAPAVIYEAMECLG
GNGYVEEAPLARYYREAPVNAIWEGSGNVMALDVLRVLSRNAGLFDDVLQGMAADLGPAGSGTVEVLSAAMRVCESDEGA
GRILTEQLALAAAAAELKRLGAGQVADAFIETRLAGQWRGTYGMLDARYDAVAILDMLYPEAM
>Mature_543_residues
MKNEEVLNQPPPISGTNAWRGDPLLVQLCERFSEPVRKDVEQLGRFVRTQEAQELARLANTELPVLKTHDRYGFRVDQVE
YHPAYHALMRRSASAGLHSSIWEDGEDEKGQRHQARAARFYLTAQLECGHLCPMTMTSAALAALMSNPALFRAWAPRVIA
RKYDNANRPAAQKQGVTLGMGMTEKQGGTDVRANTTRAEPAGEGLYRLNGHKWFMSAPMSDGFLVLAQAEEGLSCFLLPR
VTDDGATNGFRFQRLKDKLGNRSNASSEVEFEGALGYLVGEPGAGIRTIMDMVTLTRLDCALASSGLMRAALAEAVHHAR
HRSVFGKALFEQPLMNRVLADLALDVAAATALAFRLARSFDEAANGRAEAAYARVMTPVTKYWVCKIAPAVIYEAMECLG
GNGYVEEAPLARYYREAPVNAIWEGSGNVMALDVLRVLSRNAGLFDDVLQGMAADLGPAGSGTVEVLSAAMRVCESDEGA
GRILTEQLALAAAAAELKRLGAGQVADAFIETRLAGQWRGTYGMLDARYDAVAILDMLYPEAM

Specific function: May help to prevent alkylation damage by protecting DNA and destroying alkylating agents [H]

COG id: COG1960

COG function: function code I; Acyl-CoA dehydrogenases

Gene ontology:

Cell location: Cytoplasm (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the acyl-CoA dehydrogenase family [H]

Homologues:

Organism=Homo sapiens, GI4557233, Length=269, Percent_Identity=30.4832713754647, Blast_Score=107, Evalue=4e-23,
Organism=Homo sapiens, GI226958412, Length=304, Percent_Identity=25.6578947368421, Blast_Score=98, Evalue=2e-20,
Organism=Homo sapiens, GI226958414, Length=304, Percent_Identity=25.6578947368421, Blast_Score=98, Evalue=2e-20,
Organism=Homo sapiens, GI4501859, Length=257, Percent_Identity=28.0155642023346, Blast_Score=97, Evalue=4e-20,
Organism=Homo sapiens, GI4557231, Length=268, Percent_Identity=29.1044776119403, Blast_Score=91, Evalue=3e-18,
Organism=Homo sapiens, GI187960098, Length=268, Percent_Identity=29.1044776119403, Blast_Score=91, Evalue=3e-18,
Organism=Homo sapiens, GI4557235, Length=269, Percent_Identity=26.3940520446097, Blast_Score=88, Evalue=2e-17,
Organism=Homo sapiens, GI76496475, Length=269, Percent_Identity=27.1375464684015, Blast_Score=88, Evalue=3e-17,
Organism=Homo sapiens, GI21361497, Length=271, Percent_Identity=25.830258302583, Blast_Score=80, Evalue=6e-15,
Organism=Homo sapiens, GI4501857, Length=270, Percent_Identity=27.4074074074074, Blast_Score=79, Evalue=1e-14,
Organism=Homo sapiens, GI7656849, Length=265, Percent_Identity=26.7924528301887, Blast_Score=76, Evalue=7e-14,
Organism=Escherichia coli, GI87082384, Length=515, Percent_Identity=45.8252427184466, Blast_Score=434, Evalue=1e-123,
Organism=Escherichia coli, GI87081958, Length=258, Percent_Identity=26.7441860465116, Blast_Score=76, Evalue=6e-15,
Organism=Caenorhabditis elegans, GI86563381, Length=443, Percent_Identity=34.0857787810384, Blast_Score=213, Evalue=2e-55,
Organism=Caenorhabditis elegans, GI86563383, Length=443, Percent_Identity=34.0857787810384, Blast_Score=213, Evalue=2e-55,
Organism=Caenorhabditis elegans, GI17538396, Length=270, Percent_Identity=28.5185185185185, Blast_Score=102, Evalue=5e-22,
Organism=Caenorhabditis elegans, GI17508101, Length=256, Percent_Identity=25, Blast_Score=93, Evalue=4e-19,
Organism=Caenorhabditis elegans, GI17569725, Length=269, Percent_Identity=25.2788104089219, Blast_Score=91, Evalue=2e-18,
Organism=Caenorhabditis elegans, GI71985184, Length=277, Percent_Identity=26.3537906137184, Blast_Score=89, Evalue=9e-18,
Organism=Caenorhabditis elegans, GI17506239, Length=265, Percent_Identity=23.0188679245283, Blast_Score=86, Evalue=6e-17,
Organism=Caenorhabditis elegans, GI17534899, Length=272, Percent_Identity=25, Blast_Score=85, Evalue=1e-16,
Organism=Caenorhabditis elegans, GI17533517, Length=267, Percent_Identity=26.2172284644195, Blast_Score=80, Evalue=4e-15,
Organism=Caenorhabditis elegans, GI17570075, Length=269, Percent_Identity=24.907063197026, Blast_Score=79, Evalue=7e-15,
Organism=Caenorhabditis elegans, GI71985192, Length=221, Percent_Identity=26.6968325791855, Blast_Score=72, Evalue=6e-13,
Organism=Caenorhabditis elegans, GI17551932, Length=327, Percent_Identity=24.7706422018349, Blast_Score=72, Evalue=1e-12,
Organism=Caenorhabditis elegans, GI17505929, Length=329, Percent_Identity=26.7477203647416, Blast_Score=71, Evalue=2e-12,
Organism=Caenorhabditis elegans, GI71990804, Length=204, Percent_Identity=25.4901960784314, Blast_Score=70, Evalue=2e-12,
Organism=Drosophila melanogaster, GI21356377, Length=262, Percent_Identity=29.0076335877863, Blast_Score=102, Evalue=7e-22,
Organism=Drosophila melanogaster, GI21355753, Length=262, Percent_Identity=28.6259541984733, Blast_Score=94, Evalue=4e-19,
Organism=Drosophila melanogaster, GI24646207, Length=271, Percent_Identity=26.5682656826568, Blast_Score=92, Evalue=1e-18,
Organism=Drosophila melanogaster, GI281363737, Length=280, Percent_Identity=25.3571428571429, Blast_Score=89, Evalue=7e-18,
Organism=Drosophila melanogaster, GI24660351, Length=273, Percent_Identity=29.3040293040293, Blast_Score=89, Evalue=1e-17,
Organism=Drosophila melanogaster, GI24666513, Length=269, Percent_Identity=23.7918215613383, Blast_Score=86, Evalue=6e-17,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006089
- InterPro:   IPR006090
- InterPro:   IPR006091
- InterPro:   IPR009075
- InterPro:   IPR009100 [H]

Pfam domain/function: PF00441 Acyl-CoA_dh_1; PF02770 Acyl-CoA_dh_M [H]

EC number: NA

Molecular weight: Translated: 59121; Mature: 59121

Theoretical pI: Translated: 6.21; Mature: 6.21

Prosite motif: PS00072 ACYL_COA_DH_1 ; PS00073 ACYL_COA_DH_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
3.9 %Met     (Translated Protein)
5.3 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
3.9 %Met     (Mature Protein)
5.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKNEEVLNQPPPISGTNAWRGDPLLVQLCERFSEPVRKDVEQLGRFVRTQEAQELARLAN
CCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHC
TELPVLKTHDRYGFRVDQVEYHPAYHALMRRSASAGLHSSIWEDGEDEKGQRHQARAARF
CCCCEEEECCCCCCEECCEEHHHHHHHHHHHHHCCCHHHHHCCCCCCCCCHHHHHHHHEE
YLTAQLECGHLCPMTMTSAALAALMSNPALFRAWAPRVIARKYDNANRPAAQKQGVTLGM
EEEEECCCCCCCCHHHHHHHHHHHHCCCHHHHHHHHHHHHHHCCCCCCCCHHHCCCEEEC
GMTEKQGGTDVRANTTRAEPAGEGLYRLNGHKWFMSAPMSDGFLVLAQAEEGLSCFLLPR
CCCCCCCCCCCCCCCCCCCCCCCCCEEECCCEEEEECCCCCCEEEEEECCCCCEEEEEEE
VTDDGATNGFRFQRLKDKLGNRSNASSEVEFEGALGYLVGEPGAGIRTIMDMVTLTRLDC
ECCCCCCCCHHHHHHHHHHCCCCCCCCCEEECCCEEEEECCCCCHHHHHHHHHHHHHHHH
ALASSGLMRAALAEAVHHARHRSVFGKALFEQPLMNRVLADLALDVAAATALAFRLARSF
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
DEAANGRAEAAYARVMTPVTKYWVCKIAPAVIYEAMECLGGNGYVEEAPLARYYREAPVN
HHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHCCCC
AIWEGSGNVMALDVLRVLSRNAGLFDDVLQGMAADLGPAGSGTVEVLSAAMRVCESDEGA
EEECCCCCEEHHHHHHHHHCCCCHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHCCCCCC
GRILTEQLALAAAAAELKRLGAGQVADAFIETRLAGQWRGTYGMLDARYDAVAILDMLYP
CHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHCC
EAM
CCC
>Mature Secondary Structure
MKNEEVLNQPPPISGTNAWRGDPLLVQLCERFSEPVRKDVEQLGRFVRTQEAQELARLAN
CCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHC
TELPVLKTHDRYGFRVDQVEYHPAYHALMRRSASAGLHSSIWEDGEDEKGQRHQARAARF
CCCCEEEECCCCCCEECCEEHHHHHHHHHHHHHCCCHHHHHCCCCCCCCCHHHHHHHHEE
YLTAQLECGHLCPMTMTSAALAALMSNPALFRAWAPRVIARKYDNANRPAAQKQGVTLGM
EEEEECCCCCCCCHHHHHHHHHHHHCCCHHHHHHHHHHHHHHCCCCCCCCHHHCCCEEEC
GMTEKQGGTDVRANTTRAEPAGEGLYRLNGHKWFMSAPMSDGFLVLAQAEEGLSCFLLPR
CCCCCCCCCCCCCCCCCCCCCCCCCEEECCCEEEEECCCCCCEEEEEECCCCCEEEEEEE
VTDDGATNGFRFQRLKDKLGNRSNASSEVEFEGALGYLVGEPGAGIRTIMDMVTLTRLDC
ECCCCCCCCHHHHHHHHHHCCCCCCCCCEEECCCEEEEECCCCCHHHHHHHHHHHHHHHH
ALASSGLMRAALAEAVHHARHRSVFGKALFEQPLMNRVLADLALDVAAATALAFRLARSF
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
DEAANGRAEAAYARVMTPVTKYWVCKIAPAVIYEAMECLGGNGYVEEAPLARYYREAPVN
HHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHCCCC
AIWEGSGNVMALDVLRVLSRNAGLFDDVLQGMAADLGPAGSGTVEVLSAAMRVCESDEGA
EEECCCCCEEHHHHHHHHHCCCCHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHCCCCCC
GRILTEQLALAAAAAELKRLGAGQVADAFIETRLAGQWRGTYGMLDARYDAVAILDMLYP
CHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHCC
EAM
CCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 7961409; 7610040; 9278503 [H]