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The map label for this gene is dinB1 [H]

Identifier: 110633697

GI number: 110633697

Start: 1437056

End: 1438366

Strand: Reverse

Name: dinB1 [H]

Synonym: Meso_1344

Alternate gene names: 110633697

Gene position: 1438366-1437056 (Counterclockwise)

Preceding gene: 110633699

Following gene: 110633693

Centisome position: 32.6

GC content: 63.08

Gene sequence:

>1311_bases
ATGGCTGTCAACGCTCCTCTGCAAAGCCTCTGCCGCGATTGCCTTACCGGTGCCGGAGTTGGCGAGCGGCGCTGCAAGGC
GTGCGGCAGCCCTCGCATGGTGCGGCACGAGGAGCTTTGCAGCCTTTCAATCGCCCATGTCGACTGCGACGCGTTCTATG
CCGCGGTCGAGAAGCGAGACAATCAGGAGTTGCGCGACAAGCCAGTGATCATCGGTGGCGGCAAGCGCGGCGTGGTTTCT
ACCGCGTGCTACATCGCCCGCATTCATGGCGTGCGCTCGGCCATGCCCATGTTCAAAGCGCTGGAGGCATGTCCTCACGC
GATTGTCATCAAGCCGGACATGGAAAAATATGTGCGCGTGGGACGAGAGGTCCGCGAAATGATGCAGGCGCTCACCCCTA
TGGTGGAGCCGCTGTCGATCGATGAGGCCTTCCTCGACCTCGCAGGCACCGAGCGGCTGCATGGCGCCTTGCCCGCTTTC
GTGCTGGCGCGTTTCGCCAGGGAAGTGGAACGGGAGATCGGAATCACCGTCTCGGTCGGCCTATCCTATTGCAAATTCCT
GGCGAAGGTCGCCTCCGATCTCGACAAGCCGCGCGGCTTTTCCGTCATCGGCCGGGCGGAAGCGCTCTCCTTCCTCGCCG
GGCAGCCGGTCACCACGATCTGGGGCGTCGGCAAGGCCTTCGCGGCCACGCTTGCCGCCGATGGCATCCGCACCATCGGC
CAGTTGCAGCACATGGAACGCGGCGATCTCATGCGCCGCTACGGCATCATGGGCGACCGGCTCTACCGGCTCTCGCGCGG
CGAAGATGCGCGAGCCGTTCAGCCGCGCAACGAGGCAAAGAGCGTTTCGTCCGAAACCACCTTTGACAAAGATATCTCTT
CTTTCGAGGAGTTGGTGCCGGTTCTTCGAGCATTAAGTGAACGTGTTTCCACGCGGCTAAAGAAGGCGGGCATCGCAGGA
CGGACCGTGGTTCTGAAGCTGAAAACGGCTGATTTCCGCATCCGTACGCGCAACCGGCAGCTTGCCGATCCCACTCGTCT
TGCCGACCGGATCTTTTCCACGGGATTGGACATGCTCAAGCGCGAGGCGGACGGCACGTTCTTCCGCCTGATCGGCATCG
GCGTCAGCGATCTGACGGACGCCGCCAAAGCCGACCCGCCGGACCTTGTCGACCGCCTTTCCCATAAGCGGGCGCTGGCA
GAGGGCGCGATCGATGCGCTCAGGGCGAAGTTTGGAAATCAGGCGGTCGAGATGGGCTACACCTTCGGCCGCTTCCGCCG
TTCGCGGCCGGAGCCGGAAATCGAGGAGTGA

Upstream 100 bases:

>100_bases
ACCAACGGGACGATGGTGACCGTCACGTTTCTCTCCACCGCTTGTATGGCAATGCGCATTGTTCTATGATTTTGTTCTTC
TTATGTTCCCATAATGATCC

Downstream 100 bases:

>100_bases
CCGCCCGGGCGGAAGGACCTTAGTTGACGAGCGTTGCTCGGCTGCATGACGCTCCATTCACGCGGATATCGGCCTCGCCC
AGACGGACGCCGAGCGCCGT

Product: DNA polymerase IV

Products: NA

Alternate protein names: Pol IV 1 [H]

Number of amino acids: Translated: 436; Mature: 435

Protein sequence:

>436_residues
MAVNAPLQSLCRDCLTGAGVGERRCKACGSPRMVRHEELCSLSIAHVDCDAFYAAVEKRDNQELRDKPVIIGGGKRGVVS
TACYIARIHGVRSAMPMFKALEACPHAIVIKPDMEKYVRVGREVREMMQALTPMVEPLSIDEAFLDLAGTERLHGALPAF
VLARFAREVEREIGITVSVGLSYCKFLAKVASDLDKPRGFSVIGRAEALSFLAGQPVTTIWGVGKAFAATLAADGIRTIG
QLQHMERGDLMRRYGIMGDRLYRLSRGEDARAVQPRNEAKSVSSETTFDKDISSFEELVPVLRALSERVSTRLKKAGIAG
RTVVLKLKTADFRIRTRNRQLADPTRLADRIFSTGLDMLKREADGTFFRLIGIGVSDLTDAAKADPPDLVDRLSHKRALA
EGAIDALRAKFGNQAVEMGYTFGRFRRSRPEPEIEE

Sequences:

>Translated_436_residues
MAVNAPLQSLCRDCLTGAGVGERRCKACGSPRMVRHEELCSLSIAHVDCDAFYAAVEKRDNQELRDKPVIIGGGKRGVVS
TACYIARIHGVRSAMPMFKALEACPHAIVIKPDMEKYVRVGREVREMMQALTPMVEPLSIDEAFLDLAGTERLHGALPAF
VLARFAREVEREIGITVSVGLSYCKFLAKVASDLDKPRGFSVIGRAEALSFLAGQPVTTIWGVGKAFAATLAADGIRTIG
QLQHMERGDLMRRYGIMGDRLYRLSRGEDARAVQPRNEAKSVSSETTFDKDISSFEELVPVLRALSERVSTRLKKAGIAG
RTVVLKLKTADFRIRTRNRQLADPTRLADRIFSTGLDMLKREADGTFFRLIGIGVSDLTDAAKADPPDLVDRLSHKRALA
EGAIDALRAKFGNQAVEMGYTFGRFRRSRPEPEIEE
>Mature_435_residues
AVNAPLQSLCRDCLTGAGVGERRCKACGSPRMVRHEELCSLSIAHVDCDAFYAAVEKRDNQELRDKPVIIGGGKRGVVST
ACYIARIHGVRSAMPMFKALEACPHAIVIKPDMEKYVRVGREVREMMQALTPMVEPLSIDEAFLDLAGTERLHGALPAFV
LARFAREVEREIGITVSVGLSYCKFLAKVASDLDKPRGFSVIGRAEALSFLAGQPVTTIWGVGKAFAATLAADGIRTIGQ
LQHMERGDLMRRYGIMGDRLYRLSRGEDARAVQPRNEAKSVSSETTFDKDISSFEELVPVLRALSERVSTRLKKAGIAGR
TVVLKLKTADFRIRTRNRQLADPTRLADRIFSTGLDMLKREADGTFFRLIGIGVSDLTDAAKADPPDLVDRLSHKRALAE
GAIDALRAKFGNQAVEMGYTFGRFRRSRPEPEIEE

Specific function: Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by polIV. Exhibits

COG id: COG0389

COG function: function code L; Nucleotidyltransferase/DNA polymerase involved in DNA repair

Gene ontology:

Cell location: Cytoplasm (Probable) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 umuC domain [H]

Homologues:

Organism=Homo sapiens, GI84043967, Length=342, Percent_Identity=28.6549707602339, Blast_Score=117, Evalue=2e-26,
Organism=Homo sapiens, GI7706681, Length=343, Percent_Identity=28.5714285714286, Blast_Score=117, Evalue=2e-26,
Organism=Homo sapiens, GI7705344, Length=108, Percent_Identity=46.2962962962963, Blast_Score=105, Evalue=1e-22,
Organism=Homo sapiens, GI154350220, Length=362, Percent_Identity=25.9668508287293, Blast_Score=101, Evalue=2e-21,
Organism=Escherichia coli, GI1786425, Length=342, Percent_Identity=39.4736842105263, Blast_Score=199, Evalue=3e-52,
Organism=Escherichia coli, GI1787432, Length=304, Percent_Identity=26.3157894736842, Blast_Score=87, Evalue=2e-18,
Organism=Caenorhabditis elegans, GI193205700, Length=391, Percent_Identity=28.6445012787724, Blast_Score=134, Evalue=1e-31,
Organism=Caenorhabditis elegans, GI193205702, Length=343, Percent_Identity=26.2390670553936, Blast_Score=94, Evalue=1e-19,
Organism=Caenorhabditis elegans, GI17537959, Length=308, Percent_Identity=25, Blast_Score=89, Evalue=4e-18,
Organism=Drosophila melanogaster, GI21355641, Length=336, Percent_Identity=25, Blast_Score=95, Evalue=8e-20,
Organism=Drosophila melanogaster, GI24644984, Length=336, Percent_Identity=25, Blast_Score=95, Evalue=8e-20,
Organism=Drosophila melanogaster, GI19923006, Length=344, Percent_Identity=25, Blast_Score=91, Evalue=2e-18,
Organism=Drosophila melanogaster, GI24668444, Length=210, Percent_Identity=29.5238095238095, Blast_Score=72, Evalue=1e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR017962
- InterPro:   IPR017961
- InterPro:   IPR001126
- InterPro:   IPR017963
- InterPro:   IPR022880 [H]

Pfam domain/function: PF00817 IMS [H]

EC number: =2.7.7.7 [H]

Molecular weight: Translated: 48039; Mature: 47908

Theoretical pI: Translated: 9.42; Mature: 9.42

Prosite motif: PS50173 UMUC

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.1 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
5.0 %Cys+Met (Translated Protein)
2.1 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
4.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAVNAPLQSLCRDCLTGAGVGERRCKACGSPRMVRHEELCSLSIAHVDCDAFYAAVEKRD
CCCCCHHHHHHHHHHHCCCCCHHHHHHCCCCCCHHHHHHHHHHHHHCCHHHHHHHHHHCC
NQELRDKPVIIGGGKRGVVSTACYIARIHGVRSAMPMFKALEACPHAIVIKPDMEKYVRV
CHHHCCCCEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEECCCHHHHHHH
GREVREMMQALTPMVEPLSIDEAFLDLAGTERLHGALPAFVLARFAREVEREIGITVSVG
HHHHHHHHHHHHHHHCCCCHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHCCEEEHH
LSYCKFLAKVASDLDKPRGFSVIGRAEALSFLAGQPVTTIWGVGKAFAATLAADGIRTIG
HHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHH
QLQHMERGDLMRRYGIMGDRLYRLSRGEDARAVQPRNEAKSVSSETTFDKDISSFEELVP
HHHHHHHHHHHHHHCCHHHHHHHHCCCCCCCCCCCCHHHHHCCCCCHHHHHHHHHHHHHH
VLRALSERVSTRLKKAGIAGRTVVLKLKTADFRIRTRNRQLADPTRLADRIFSTGLDMLK
HHHHHHHHHHHHHHHCCCCCCEEEEEEECCCEEEEECCCCCCCHHHHHHHHHHHHHHHHH
READGTFFRLIGIGVSDLTDAAKADPPDLVDRLSHKRALAEGAIDALRAKFGNQAVEMGY
HHCCCCEEEEECCCHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHH
TFGRFRRSRPEPEIEE
HHHHHHCCCCCCCCCC
>Mature Secondary Structure 
AVNAPLQSLCRDCLTGAGVGERRCKACGSPRMVRHEELCSLSIAHVDCDAFYAAVEKRD
CCCCHHHHHHHHHHHCCCCCHHHHHHCCCCCCHHHHHHHHHHHHHCCHHHHHHHHHHCC
NQELRDKPVIIGGGKRGVVSTACYIARIHGVRSAMPMFKALEACPHAIVIKPDMEKYVRV
CHHHCCCCEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEECCCHHHHHHH
GREVREMMQALTPMVEPLSIDEAFLDLAGTERLHGALPAFVLARFAREVEREIGITVSVG
HHHHHHHHHHHHHHHCCCCHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHCCEEEHH
LSYCKFLAKVASDLDKPRGFSVIGRAEALSFLAGQPVTTIWGVGKAFAATLAADGIRTIG
HHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHH
QLQHMERGDLMRRYGIMGDRLYRLSRGEDARAVQPRNEAKSVSSETTFDKDISSFEELVP
HHHHHHHHHHHHHHCCHHHHHHHHCCCCCCCCCCCCHHHHHCCCCCHHHHHHHHHHHHHH
VLRALSERVSTRLKKAGIAGRTVVLKLKTADFRIRTRNRQLADPTRLADRIFSTGLDMLK
HHHHHHHHHHHHHHHCCCCCCEEEEEEECCCEEEEECCCCCCCHHHHHHHHHHHHHHHHH
READGTFFRLIGIGVSDLTDAAKADPPDLVDRLSHKRALAEGAIDALRAKFGNQAVEMGY
HHCCCCEEEEECCCHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHH
TFGRFRRSRPEPEIEE
HHHHHHCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 11214968 [H]