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The map label for this gene is gpt

Identifier: 110633688

GI number: 110633688

Start: 1429301

End: 1429798

Strand: Reverse

Name: gpt

Synonym: Meso_1335

Alternate gene names: 110633688

Gene position: 1429798-1429301 (Counterclockwise)

Preceding gene: 110633691

Following gene: 110633687

Centisome position: 32.4

GC content: 58.23

Gene sequence:

>498_bases
ATGTCCCTTCCAGAAAAAGCCTTTCCCGTCTCTTGGGACCAGTTCCACCGCGATGCCCGCGCGCTCGCCTGGCGTCTTGC
CGGCACGAACGGACGATGGCAGGCCATCGTGTGCATCACGCGCGGCGGGCTTGTCCCGGCGGCTGTGATTGCACGCGAAC
TGGGCATCCGCCTGATCGAAACCGTCTGCATCGCGTCCTATCACGATTACAGCGAGCAGGGGGAACTGAAGGTCCTGAAA
GAGATTTCTCCCTCCCTTCTCGAGGAGGACGGGCAAAACATCCTGATCGTCGATGATCTGACGGACACGGGCAAGACGGC
CGCCATTGTGCGCGCGATGATGCCCAAGGCCCATTTCGCCACGGTTTACGCCAAGCCCAAGGGGCGGCCCCTCGTAGATA
CTTTTGTCACCGAGGTTTCACAGGATACCTGGATCTATTTTCCCTGGGATTTGGGATTTTCTTATCAAAAACCTATTGCC
GACGGAGAAATCGGCTGA

Upstream 100 bases:

>100_bases
AATTCCAGAAAGGAGGGCTGCTCTTGCCACTTCCCCGTTTTTCCGGCTAATTCCCGGCGCATTCCAGCTATAGCGGCCTG
CATCTCAGGAGTGCGCGCGA

Downstream 100 bases:

>100_bases
TTTTCCGCGCCGAAATCGCCTGGCGCTTATTTGCCTATAGCCGGCGGCGACTTATCTTCACAATTGGAAACATTCCGATG
GTGAGGTGTGAATGTAATGA

Product: xanthine-guanine phosphoribosyltransferase

Products: NA

Alternate protein names: Xanthine-guanine phosphoribosyltransferase; XGPRT

Number of amino acids: Translated: 165; Mature: 164

Protein sequence:

>165_residues
MSLPEKAFPVSWDQFHRDARALAWRLAGTNGRWQAIVCITRGGLVPAAVIARELGIRLIETVCIASYHDYSEQGELKVLK
EISPSLLEEDGQNILIVDDLTDTGKTAAIVRAMMPKAHFATVYAKPKGRPLVDTFVTEVSQDTWIYFPWDLGFSYQKPIA
DGEIG

Sequences:

>Translated_165_residues
MSLPEKAFPVSWDQFHRDARALAWRLAGTNGRWQAIVCITRGGLVPAAVIARELGIRLIETVCIASYHDYSEQGELKVLK
EISPSLLEEDGQNILIVDDLTDTGKTAAIVRAMMPKAHFATVYAKPKGRPLVDTFVTEVSQDTWIYFPWDLGFSYQKPIA
DGEIG
>Mature_164_residues
SLPEKAFPVSWDQFHRDARALAWRLAGTNGRWQAIVCITRGGLVPAAVIARELGIRLIETVCIASYHDYSEQGELKVLKE
ISPSLLEEDGQNILIVDDLTDTGKTAAIVRAMMPKAHFATVYAKPKGRPLVDTFVTEVSQDTWIYFPWDLGFSYQKPIAD
GEIG

Specific function: Acts on guanine, xanthine and to a lesser extent hypoxanthine

COG id: COG0503

COG function: function code F; Adenine/guanine phosphoribosyltransferases and related PRPP-binding proteins

Gene ontology:

Cell location: Cell inner membrane; Peripheral membrane protein

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the purine/pyrimidine phosphoribosyltransferase family. XGPT subfamily

Homologues:

Organism=Escherichia coli, GI1786433, Length=155, Percent_Identity=50.9677419354839, Blast_Score=162, Evalue=1e-41,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): XGPT_MESSB (Q11IP4)

Other databases:

- EMBL:   CP000390
- RefSeq:   YP_673896.1
- STRING:   Q11IP4
- GeneID:   4181608
- GenomeReviews:   CP000390_GR
- KEGG:   mes:Meso_1335
- NMPDR:   fig|266779.1.peg.2255
- eggNOG:   COG0503
- HOGENOM:   HBG503428
- OMA:   LVDTFIT
- PhylomeDB:   Q11IP4
- ProtClustDB:   PRK09177
- BioCyc:   MSP266779:MESO_1335-MONOMER
- HAMAP:   MF_01903
- InterPro:   IPR000836

Pfam domain/function: PF00156 Pribosyltran

EC number: =2.4.2.22

Molecular weight: Translated: 18364; Mature: 18233

Theoretical pI: Translated: 5.25; Mature: 5.25

Prosite motif: PS00103 PUR_PYR_PR_TRANSFER

Important sites: BINDING 102-102 BINDING 145-145

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
1.2 %Met     (Mature Protein)
2.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSLPEKAFPVSWDQFHRDARALAWRLAGTNGRWQAIVCITRGGLVPAAVIARELGIRLIE
CCCCCCCCCCCHHHHHHHHHHHEEEEECCCCCEEEEEEEECCCCHHHHHHHHHHHHHHHH
TVCIASYHDYSEQGELKVLKEISPSLLEEDGQNILIVDDLTDTGKTAAIVRAMMPKAHFA
HHHHHHCCCCCCCCHHHHHHHCCHHHHHHCCCEEEEEECCCCCCHHHHHHHHHCCCCCEE
TVYAKPKGRPLVDTFVTEVSQDTWIYFPWDLGFSYQKPIADGEIG
EEEECCCCCCHHHHHHHHCCCCCEEEEEECCCCCCCCCCCCCCCC
>Mature Secondary Structure 
SLPEKAFPVSWDQFHRDARALAWRLAGTNGRWQAIVCITRGGLVPAAVIARELGIRLIE
CCCCCCCCCCHHHHHHHHHHHEEEEECCCCCEEEEEEEECCCCHHHHHHHHHHHHHHHH
TVCIASYHDYSEQGELKVLKEISPSLLEEDGQNILIVDDLTDTGKTAAIVRAMMPKAHFA
HHHHHHCCCCCCCCHHHHHHHCCHHHHHHCCCEEEEEECCCCCCHHHHHHHHHCCCCCEE
TVYAKPKGRPLVDTFVTEVSQDTWIYFPWDLGFSYQKPIADGEIG
EEEECCCCCCHHHHHHHHCCCCCEEEEEECCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: NA