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The map label for this gene is fabF [H]

Identifier: 110633672

GI number: 110633672

Start: 1409815

End: 1410999

Strand: Reverse

Name: fabF [H]

Synonym: Meso_1319

Alternate gene names: 110633672

Gene position: 1410999-1409815 (Counterclockwise)

Preceding gene: 110633673

Following gene: 110633671

Centisome position: 31.98

GC content: 65.23

Gene sequence:

>1185_bases
ATGAATCCGACAGACGTGCTCATCACCGGCATCGGTGTCGTCTCCTCGCTGGGTCTCGGCGCCGACGCCCATTGGCAGGC
CCTGACGAGGCGCGAGCCCATGCCCGCGCTCGACCTGGAGCGCTTCTCGCCCTACATCGTCCATCCCCTTCCCGAGATCG
ACTGGAGCACGCAGATCCCCAAGCGCGGGGACCAGCGGCAGATGGAGACCTGGCAGCGGCTCGGCACTTATACCGCAGGG
CTTGCCTTGGAAGATGCCGGGATCAAGGATGACGAAGCGCTCTGCGCGTCCATGGACATGATCATAGCGGCCGGCGGCGG
TGAACGGGACGTGGCGGTGGACCAGGCGATCCTCGATGCATCGCTCACACGCAACGACAATGACGTTCTCCTGAACGAAA
AGCTCACGACGGAGCTTCGCCCGACGCTCTTCCTGGCACAGCTGTCCAATCTCCTGGCCGGCAACATCTCGATCGTGCAC
AAGGTCACTGGCTCGTCGCGCACCTTCATGGGCGAAGACGGCGCCGGCGTTTCAGCCATCGAGACGGCGGCGGCGCGGAT
CCGTTCCGGCCAATCGGCACATCTGCTCGTGGGCGCGGCGTTCCAGACCGAGCATCCGGATATGCTGCTCGCCTACGAAC
TGGGCGGATATCTTCAGCGGGAGAAATGGTCGCCCGTCTGGCAACGCAACAAAGATCTGGGCGGCGGCGTGATCACCGGG
TCTGGCGCCGCGTTCCTGGTGCTCGAATCCCGTGAGCATGCGGAAAAGCGGGGCCGCACACCCTATGCCGCCATCGGCCC
CGTTGCTTCAGGCCGGGCCAGGCGGAAAGACACGGACCTGCAGAAAGACTTGGCTGCGATGCTCGCCCCGCTTCAGCAGG
ATGTCCGGCCGGTCCTCGCAATTTCCGGCGCTTCCGGCGCACATGCGCCGACGGCGGCGGAAAGGGCAGCGCTTGAGAGC
GCGGGAGCCGTGGTTCGCGGTTTCAACACGCTCACCGGGCACTTGAAGGAAGCGCAATTTCCCTTCGCCGTGGCGCTGGC
GGCGCTGGCCGTCCGGCACGGACAAGCCTACCCCGCCTTCGACCCGTCCAGTGAAAAGCCTTTCGAAAGCGCGCCCAAGG
CAGCGCTTGCCACCGCCATCGGCTATGACTGCTTCGAGGGCATGGGGCTCATCGTAGAGGCCTAA

Upstream 100 bases:

>100_bases
CCGGCGAGGAGTATTTCGTCATGAAGAACCTGTGCGCCAAGATCGACGAGCTCGTTGCCGCCAAGGCAGCCAGCTAAGCT
TTGCCTCAAAGCGAGGGGAC

Downstream 100 bases:

>100_bases
GGAGAGCGTCCATGAAGACCACCGACAGTTTCGGACGCCCGCTCGTCGCCGTTACCGGCATGGGTGTCGTCACCTCGCTC
GGCCAGGGCAAGAAGGACAA

Product: 3-oxoacyl-(acyl carrier protein) synthase II

Products: NA

Alternate protein names: 3-oxoacyl-[acyl-carrier-protein] synthase II; Beta-ketoacyl-ACP synthase II; KAS II [H]

Number of amino acids: Translated: 394; Mature: 394

Protein sequence:

>394_residues
MNPTDVLITGIGVVSSLGLGADAHWQALTRREPMPALDLERFSPYIVHPLPEIDWSTQIPKRGDQRQMETWQRLGTYTAG
LALEDAGIKDDEALCASMDMIIAAGGGERDVAVDQAILDASLTRNDNDVLLNEKLTTELRPTLFLAQLSNLLAGNISIVH
KVTGSSRTFMGEDGAGVSAIETAAARIRSGQSAHLLVGAAFQTEHPDMLLAYELGGYLQREKWSPVWQRNKDLGGGVITG
SGAAFLVLESREHAEKRGRTPYAAIGPVASGRARRKDTDLQKDLAAMLAPLQQDVRPVLAISGASGAHAPTAAERAALES
AGAVVRGFNTLTGHLKEAQFPFAVALAALAVRHGQAYPAFDPSSEKPFESAPKAALATAIGYDCFEGMGLIVEA

Sequences:

>Translated_394_residues
MNPTDVLITGIGVVSSLGLGADAHWQALTRREPMPALDLERFSPYIVHPLPEIDWSTQIPKRGDQRQMETWQRLGTYTAG
LALEDAGIKDDEALCASMDMIIAAGGGERDVAVDQAILDASLTRNDNDVLLNEKLTTELRPTLFLAQLSNLLAGNISIVH
KVTGSSRTFMGEDGAGVSAIETAAARIRSGQSAHLLVGAAFQTEHPDMLLAYELGGYLQREKWSPVWQRNKDLGGGVITG
SGAAFLVLESREHAEKRGRTPYAAIGPVASGRARRKDTDLQKDLAAMLAPLQQDVRPVLAISGASGAHAPTAAERAALES
AGAVVRGFNTLTGHLKEAQFPFAVALAALAVRHGQAYPAFDPSSEKPFESAPKAALATAIGYDCFEGMGLIVEA
>Mature_394_residues
MNPTDVLITGIGVVSSLGLGADAHWQALTRREPMPALDLERFSPYIVHPLPEIDWSTQIPKRGDQRQMETWQRLGTYTAG
LALEDAGIKDDEALCASMDMIIAAGGGERDVAVDQAILDASLTRNDNDVLLNEKLTTELRPTLFLAQLSNLLAGNISIVH
KVTGSSRTFMGEDGAGVSAIETAAARIRSGQSAHLLVGAAFQTEHPDMLLAYELGGYLQREKWSPVWQRNKDLGGGVITG
SGAAFLVLESREHAEKRGRTPYAAIGPVASGRARRKDTDLQKDLAAMLAPLQQDVRPVLAISGASGAHAPTAAERAALES
AGAVVRGFNTLTGHLKEAQFPFAVALAALAVRHGQAYPAFDPSSEKPFESAPKAALATAIGYDCFEGMGLIVEA

Specific function: Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Has a preference for short chain acid substrates and may function to supply the octanoic substrates for lipoic acid biosynthes

COG id: COG0304

COG function: function code IQ; 3-oxoacyl-(acyl-carrier-protein) synthase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the beta-ketoacyl-ACP synthases family [H]

Homologues:

Organism=Escherichia coli, GI1787337, Length=274, Percent_Identity=22.992700729927, Blast_Score=65, Evalue=9e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR017568
- InterPro:   IPR000794
- InterPro:   IPR018201
- InterPro:   IPR014031
- InterPro:   IPR014030
- InterPro:   IPR016039
- InterPro:   IPR016038 [H]

Pfam domain/function: PF00109 ketoacyl-synt; PF02801 Ketoacyl-synt_C [H]

EC number: =2.3.1.179 [H]

Molecular weight: Translated: 41885; Mature: 41885

Theoretical pI: Translated: 5.27; Mature: 5.27

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNPTDVLITGIGVVSSLGLGADAHWQALTRREPMPALDLERFSPYIVHPLPEIDWSTQIP
CCCHHEEEEHHHHHHHCCCCCCHHHHHHHHCCCCCCCCHHHCCCEEECCCCCCCCCCCCC
KRGDQRQMETWQRLGTYTAGLALEDAGIKDDEALCASMDMIIAAGGGERDVAVDQAILDA
CCCCHHHHHHHHHHCCHHHCEEEECCCCCCHHHHHHHCCEEEECCCCCCCHHHHHHHHHH
SLTRNDNDVLLNEKLTTELRPTLFLAQLSNLLAGNISIVHKVTGSSRTFMGEDGAGVSAI
HHCCCCCCEEECCHHHHHHHHHHHHHHHHHHHHCCEEEEEEECCCCCEEECCCCCCHHHH
ETAAARIRSGQSAHLLVGAAFQTEHPDMLLAYELGGYLQREKWSPVWQRNKDLGGGVITG
HHHHHHHHCCCCCEEEEEEEECCCCCCEEEEEECCCHHHHCCCCHHHHCCCCCCCEEEEC
SGAAFLVLESREHAEKRGRTPYAAIGPVASGRARRKDTDLQKDLAAMLAPLQQDVRPVLA
CCEEEEEEECHHHHHHCCCCCCEEECCCCCCCCCCCCCHHHHHHHHHHHHHHHCCCEEEE
ISGASGAHAPTAAERAALESAGAVVRGFNTLTGHLKEAQFPFAVALAALAVRHGQAYPAF
EECCCCCCCCHHHHHHHHHHCCHHHHCCHHHHHHHHHCCCHHHHHHHHHHHHCCCCCCCC
DPSSEKPFESAPKAALATAIGYDCFEGMGLIVEA
CCCCCCCCHHCCHHHHHHHHHHHHHCCCCEEEEC
>Mature Secondary Structure
MNPTDVLITGIGVVSSLGLGADAHWQALTRREPMPALDLERFSPYIVHPLPEIDWSTQIP
CCCHHEEEEHHHHHHHCCCCCCHHHHHHHHCCCCCCCCHHHCCCEEECCCCCCCCCCCCC
KRGDQRQMETWQRLGTYTAGLALEDAGIKDDEALCASMDMIIAAGGGERDVAVDQAILDA
CCCCHHHHHHHHHHCCHHHCEEEECCCCCCHHHHHHHCCEEEECCCCCCCHHHHHHHHHH
SLTRNDNDVLLNEKLTTELRPTLFLAQLSNLLAGNISIVHKVTGSSRTFMGEDGAGVSAI
HHCCCCCCEEECCHHHHHHHHHHHHHHHHHHHHCCEEEEEEECCCCCEEECCCCCCHHHH
ETAAARIRSGQSAHLLVGAAFQTEHPDMLLAYELGGYLQREKWSPVWQRNKDLGGGVITG
HHHHHHHHCCCCCEEEEEEEECCCCCCEEEEEECCCHHHHCCCCHHHHCCCCCCCEEEEC
SGAAFLVLESREHAEKRGRTPYAAIGPVASGRARRKDTDLQKDLAAMLAPLQQDVRPVLA
CCEEEEEEECHHHHHHCCCCCCEEECCCCCCCCCCCCCHHHHHHHHHHHHHHHCCCEEEE
ISGASGAHAPTAAERAALESAGAVVRGFNTLTGHLKEAQFPFAVALAALAVRHGQAYPAF
EECCCCCCCCHHHHHHHHHHCCHHHHCCHHHHHHHHHCCCHHHHHHHHHHHHCCCCCCCC
DPSSEKPFESAPKAALATAIGYDCFEGMGLIVEA
CCCCCCCCHHCCHHHHHHHHHHHHHCCCCEEEEC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8550484 [H]