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The map label for this gene is qor [C]

Identifier: 110633670

GI number: 110633670

Start: 1407476

End: 1408504

Strand: Reverse

Name: qor [C]

Synonym: Meso_1317

Alternate gene names: 110633670

Gene position: 1408504-1407476 (Counterclockwise)

Preceding gene: 110633671

Following gene: 110633668

Centisome position: 31.92

GC content: 63.95

Gene sequence:

>1029_bases
ATGCGTGCATTGCAACTCGTCGCGGACCGCAAGCTCGAAATCGCGGACGTATCCCCACCCCCTCCCCCCGGCCATGGTGA
GGTGACGCTTCGGATCTCCGCGGTCGCGCTCAACCACATCGATGTATGGGGCTGGCGCGGCATGGCCTTTGCCAAACGCA
AGCTGCCGCTTACCGTGGGCGCGGAGGCTTCCGGCCGGGTCGACGCTGTCGGACCCGGCGTCAGCAATCTCGTGCCGGGT
CAGCTTGTATCAATCTATGGCGCGCGCACCTGCGGGCTCTGCCGCCCCTGCCGCGAAGGCCGCGACAATCTTTGCGAGCA
TGTCGGCGGTGTGCACGGCTTTCACCTGGACGGCTTCGCGCAGGAAAAGATCAACCTGCCGGCGCGCCTCCTTGTGCCCG
CGCCGCCCGGCGTAGACGAGATCGGCGCGGCCGTGGCTCCTGTCTCATTCGGAACGGTCGAGCATATGCTGTTCGACAAT
GCGAAGCTTGAGCCCGGTGAGACAATCCTGGTTCATGCCGGCGGCTCGGGCATCGGCTCCGCCGCGATCCAGCTTGCCAA
ACGCATGGGCTGCACGGTCCTCACCACGGTGGGTTCGAACGAAAAGATCGAACGAGCGAAGGCGCTGGGCGCCGACCATG
TGATCAATTACCGCGAGGACCGCTTCGAAGGCGCCGTGCGCAAGATCACCAAAAAACGCGGCGTGGATGTAGTGTTCGAG
CATGTGGGCGCCGATACCTGGGCAGGCTCCATGCTGTGCCTCAAGCGCGGCGGGCGGCTCGTCACCTGCGGCTCGACCTC
GGGCGTTTCCACGAATATGAACCTGATGCAGCTCTTCCAGCAGCAGCTCAAGATCCTCGGCTCCTTCGGCTGCCGCATGG
AGAACATGGCCGACGCCATGCAGAAAATGGCAGCCGGGATCGTCGCTCCGGTCATCGATACCGAGGTCGGCTTTGAGGCC
ATCGACACGGCTTTGAAGCGCATGGAAGGCCGGGATGTTTTCGGCAAGATCATCCTGCGTGTGGGCTAG

Upstream 100 bases:

>100_bases
CGTGCTTTCGAACTCGTTCGGCTTCGGCGGCCAGAACACTTGCCTTGTCATGGCGCGCGAAGCGGGTTAAGCGACCGGCC
TGTCTAAAGGACCGGCATTC

Downstream 100 bases:

>100_bases
AGCCTTTCATGGTTAGATTGAACCATTCTGCCGGAGCTGGTTTGGCTCAAGGTCAAGGGATTTGGCGAAGGCCGTATCGG
GCATACGGTCGAGCCAAAGC

Product: zinc-binding alcohol dehydrogenase

Products: NA

Alternate protein names: Acryloyl-CoA reductase [H]

Number of amino acids: Translated: 342; Mature: 342

Protein sequence:

>342_residues
MRALQLVADRKLEIADVSPPPPPGHGEVTLRISAVALNHIDVWGWRGMAFAKRKLPLTVGAEASGRVDAVGPGVSNLVPG
QLVSIYGARTCGLCRPCREGRDNLCEHVGGVHGFHLDGFAQEKINLPARLLVPAPPGVDEIGAAVAPVSFGTVEHMLFDN
AKLEPGETILVHAGGSGIGSAAIQLAKRMGCTVLTTVGSNEKIERAKALGADHVINYREDRFEGAVRKITKKRGVDVVFE
HVGADTWAGSMLCLKRGGRLVTCGSTSGVSTNMNLMQLFQQQLKILGSFGCRMENMADAMQKMAAGIVAPVIDTEVGFEA
IDTALKRMEGRDVFGKIILRVG

Sequences:

>Translated_342_residues
MRALQLVADRKLEIADVSPPPPPGHGEVTLRISAVALNHIDVWGWRGMAFAKRKLPLTVGAEASGRVDAVGPGVSNLVPG
QLVSIYGARTCGLCRPCREGRDNLCEHVGGVHGFHLDGFAQEKINLPARLLVPAPPGVDEIGAAVAPVSFGTVEHMLFDN
AKLEPGETILVHAGGSGIGSAAIQLAKRMGCTVLTTVGSNEKIERAKALGADHVINYREDRFEGAVRKITKKRGVDVVFE
HVGADTWAGSMLCLKRGGRLVTCGSTSGVSTNMNLMQLFQQQLKILGSFGCRMENMADAMQKMAAGIVAPVIDTEVGFEA
IDTALKRMEGRDVFGKIILRVG
>Mature_342_residues
MRALQLVADRKLEIADVSPPPPPGHGEVTLRISAVALNHIDVWGWRGMAFAKRKLPLTVGAEASGRVDAVGPGVSNLVPG
QLVSIYGARTCGLCRPCREGRDNLCEHVGGVHGFHLDGFAQEKINLPARLLVPAPPGVDEIGAAVAPVSFGTVEHMLFDN
AKLEPGETILVHAGGSGIGSAAIQLAKRMGCTVLTTVGSNEKIERAKALGADHVINYREDRFEGAVRKITKKRGVDVVFE
HVGADTWAGSMLCLKRGGRLVTCGSTSGVSTNMNLMQLFQQQLKILGSFGCRMENMADAMQKMAAGIVAPVIDTEVGFEA
IDTALKRMEGRDVFGKIILRVG

Specific function: Plays a role in autotrophic carbon fixation via the 3- hydroxypropionate/4-hydroxybutyrate cycle. Catalyzes the acryloyl- CoA dependent NADPH oxidation and formation of propionyl-CoA. Inactive towards 3-hydroxypropionyl-CoA, NADH and crotonyl-CoA [H]

COG id: COG0604

COG function: function code CR; NADPH:quinone reductase and related Zn-dependent oxidoreductases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the zinc-containing alcohol dehydrogenase family [H]

Homologues:

Organism=Homo sapiens, GI22538446, Length=335, Percent_Identity=28.955223880597, Blast_Score=119, Evalue=4e-27,
Organism=Homo sapiens, GI22538444, Length=335, Percent_Identity=28.955223880597, Blast_Score=119, Evalue=4e-27,
Organism=Homo sapiens, GI18379349, Length=342, Percent_Identity=27.7777777777778, Blast_Score=103, Evalue=2e-22,
Organism=Homo sapiens, GI194239674, Length=330, Percent_Identity=23.9393939393939, Blast_Score=91, Evalue=2e-18,
Organism=Homo sapiens, GI13236495, Length=330, Percent_Identity=23.9393939393939, Blast_Score=91, Evalue=2e-18,
Organism=Homo sapiens, GI41872631, Length=224, Percent_Identity=30.8035714285714, Blast_Score=86, Evalue=6e-17,
Organism=Homo sapiens, GI28557745, Length=257, Percent_Identity=30.3501945525292, Blast_Score=81, Evalue=1e-15,
Organism=Homo sapiens, GI4501929, Length=332, Percent_Identity=28.9156626506024, Blast_Score=76, Evalue=5e-14,
Organism=Homo sapiens, GI197927207, Length=190, Percent_Identity=27.8947368421053, Blast_Score=73, Evalue=4e-13,
Organism=Homo sapiens, GI156627571, Length=327, Percent_Identity=28.4403669724771, Blast_Score=72, Evalue=1e-12,
Organism=Homo sapiens, GI226059159, Length=190, Percent_Identity=29.4736842105263, Blast_Score=70, Evalue=2e-12,
Organism=Homo sapiens, GI226059133, Length=190, Percent_Identity=29.4736842105263, Blast_Score=70, Evalue=2e-12,
Organism=Escherichia coli, GI1790485, Length=302, Percent_Identity=30.1324503311258, Blast_Score=117, Evalue=1e-27,
Organism=Escherichia coli, GI1790045, Length=341, Percent_Identity=29.3255131964809, Blast_Score=96, Evalue=4e-21,
Organism=Escherichia coli, GI1788073, Length=285, Percent_Identity=29.8245614035088, Blast_Score=92, Evalue=6e-20,
Organism=Escherichia coli, GI87081918, Length=318, Percent_Identity=25.7861635220126, Blast_Score=80, Evalue=2e-16,
Organism=Escherichia coli, GI1787863, Length=200, Percent_Identity=31, Blast_Score=73, Evalue=3e-14,
Organism=Escherichia coli, GI1786518, Length=329, Percent_Identity=27.9635258358663, Blast_Score=72, Evalue=4e-14,
Organism=Escherichia coli, GI226510992, Length=160, Percent_Identity=31.875, Blast_Score=69, Evalue=6e-13,
Organism=Escherichia coli, GI1788407, Length=221, Percent_Identity=28.9592760180996, Blast_Score=63, Evalue=3e-11,
Organism=Caenorhabditis elegans, GI71988145, Length=239, Percent_Identity=30.1255230125523, Blast_Score=72, Evalue=3e-13,
Organism=Caenorhabditis elegans, GI212642053, Length=218, Percent_Identity=28.8990825688073, Blast_Score=69, Evalue=3e-12,
Organism=Caenorhabditis elegans, GI17562584, Length=332, Percent_Identity=25.3012048192771, Blast_Score=68, Evalue=6e-12,
Organism=Caenorhabditis elegans, GI17507255, Length=305, Percent_Identity=26.2295081967213, Blast_Score=65, Evalue=6e-11,
Organism=Saccharomyces cerevisiae, GI6319621, Length=335, Percent_Identity=26.2686567164179, Blast_Score=96, Evalue=6e-21,
Organism=Saccharomyces cerevisiae, GI6324486, Length=332, Percent_Identity=26.5060240963855, Blast_Score=96, Evalue=1e-20,
Organism=Saccharomyces cerevisiae, GI6323961, Length=335, Percent_Identity=26.2686567164179, Blast_Score=93, Evalue=6e-20,
Organism=Saccharomyces cerevisiae, GI6322619, Length=329, Percent_Identity=28.5714285714286, Blast_Score=87, Evalue=5e-18,
Organism=Saccharomyces cerevisiae, GI6319955, Length=329, Percent_Identity=28.2674772036474, Blast_Score=84, Evalue=3e-17,
Organism=Saccharomyces cerevisiae, GI6319520, Length=260, Percent_Identity=26.1538461538462, Blast_Score=79, Evalue=8e-16,
Organism=Saccharomyces cerevisiae, GI6323729, Length=332, Percent_Identity=23.7951807228916, Blast_Score=75, Evalue=1e-14,
Organism=Drosophila melanogaster, GI24581345, Length=226, Percent_Identity=30.0884955752212, Blast_Score=89, Evalue=5e-18,
Organism=Drosophila melanogaster, GI221330659, Length=213, Percent_Identity=30.0469483568075, Blast_Score=88, Evalue=8e-18,
Organism=Drosophila melanogaster, GI19920632, Length=213, Percent_Identity=30.0469483568075, Blast_Score=88, Evalue=9e-18,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013149
- InterPro:   IPR013154
- InterPro:   IPR002085
- InterPro:   IPR002328
- InterPro:   IPR011032
- InterPro:   IPR016040
- InterPro:   IPR002364 [H]

Pfam domain/function: PF08240 ADH_N; PF00107 ADH_zinc_N [H]

EC number: =1.3.1.84 [H]

Molecular weight: Translated: 36364; Mature: 36364

Theoretical pI: Translated: 8.41; Mature: 8.41

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.3 %Cys     (Translated Protein)
3.5 %Met     (Translated Protein)
5.8 %Cys+Met (Translated Protein)
2.3 %Cys     (Mature Protein)
3.5 %Met     (Mature Protein)
5.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRALQLVADRKLEIADVSPPPPPGHGEVTLRISAVALNHIDVWGWRGMAFAKRKLPLTVG
CCHHHHHHCCCEEEEECCCCCCCCCCEEEEEEEEEEEECEEECCCCCHHHHHHCCCEEEC
AEASGRVDAVGPGVSNLVPGQLVSIYGARTCGLCRPCREGRDNLCEHVGGVHGFHLDGFA
CCCCCCEEECCCCHHHCCCCHHHHHHCCCCCCCCHHHHHHHHHHHHHHCCCCCEECCCHH
QEKINLPARLLVPAPPGVDEIGAAVAPVSFGTVEHMLFDNAKLEPGETILVHAGGSGIGS
HHHHCCCEEEEECCCCCHHHHHHHHCCCCHHHHHHHHHCCCCCCCCCEEEEECCCCCHHH
AAIQLAKRMGCTVLTTVGSNEKIERAKALGADHVINYREDRFEGAVRKITKKRGVDVVFE
HHHHHHHHCCCEEEEECCCCHHHHHHHHCCHHHHHCCHHHHHHHHHHHHHHHCCHHHHHH
HVGADTWAGSMLCLKRGGRLVTCGSTSGVSTNMNLMQLFQQQLKILGSFGCRMENMADAM
HCCCCHHCCHHHHHHCCCEEEEECCCCCCCCCHHHHHHHHHHHHHHHHHCCCHHHHHHHH
QKMAAGIVAPVIDTEVGFEAIDTALKRMEGRDVFGKIILRVG
HHHHHHHHHHHHCCCCCHHHHHHHHHHHCCCCHHHHHHEECC
>Mature Secondary Structure
MRALQLVADRKLEIADVSPPPPPGHGEVTLRISAVALNHIDVWGWRGMAFAKRKLPLTVG
CCHHHHHHCCCEEEEECCCCCCCCCCEEEEEEEEEEEECEEECCCCCHHHHHHCCCEEEC
AEASGRVDAVGPGVSNLVPGQLVSIYGARTCGLCRPCREGRDNLCEHVGGVHGFHLDGFA
CCCCCCEEECCCCHHHCCCCHHHHHHCCCCCCCCHHHHHHHHHHHHHHCCCCCEECCCHH
QEKINLPARLLVPAPPGVDEIGAAVAPVSFGTVEHMLFDNAKLEPGETILVHAGGSGIGS
HHHHCCCEEEEECCCCCHHHHHHHHCCCCHHHHHHHHHCCCCCCCCCEEEEECCCCCHHH
AAIQLAKRMGCTVLTTVGSNEKIERAKALGADHVINYREDRFEGAVRKITKKRGVDVVFE
HHHHHHHHCCCEEEEECCCCHHHHHHHHCCHHHHHCCHHHHHHHHHHHHHHHCCHHHHHH
HVGADTWAGSMLCLKRGGRLVTCGSTSGVSTNMNLMQLFQQQLKILGSFGCRMENMADAM
HCCCCHHCCHHHHHHCCCEEEEECCCCCCCCCHHHHHHHHHHHHHHHHHCCCHHHHHHHH
QKMAAGIVAPVIDTEVGFEAIDTALKRMEGRDVFGKIILRVG
HHHHHHHHHHHHCCCCCHHHHHHHHHHHCCCCHHHHHHEECC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11572479 [H]