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The map label for this gene is sigW [H]

Identifier: 110633596

GI number: 110633596

Start: 1339726

End: 1340460

Strand: Reverse

Name: sigW [H]

Synonym: Meso_1243

Alternate gene names: 110633596

Gene position: 1340460-1339726 (Counterclockwise)

Preceding gene: 110633597

Following gene: 110633591

Centisome position: 30.38

GC content: 62.31

Gene sequence:

>735_bases
ATGAGAGGTCTCGACATAGAAATGACGATGGCTCATCCCAAGCTTGATCTTGAACGGTTGAGCGATGAAGAGCTTGTTCA
TCTCGCCAGACAGGGTGGCGAAAGCGCCATTCGCCTGCTCATCAAACGCAACAACCGGTCTCTCTTCCGGGTCGCACGTG
CGGTCGTGCGTGACGACGCAGAGGCCGAGGACATCGTGCAGGAAACTTATGTCAGCGCCTTCACGAAGCTCGACTCGTTT
CGCGGCCATTCCCGGTTCTCGACCTGGCTCACCCGGATCGCCCTCAACGAGGCACTCGGGAGGGCGCGAAAGCGGTGGCC
GGCGGCCGAACTTGCTGAACTGGATATGGCGGAGGGCTGCAATGGAGGGTCGGTGATCATGTTTCCGACTTCGCTGAAGC
CGCCGGGCGCGGATGCCGAGCTCGCCCGCAAGCAGGTGCGCGACCTTCTCGAGACTGCCGTCGACGAGTTGCCCGATCCG
TTCCGGCTCGTCTTCATCCTCCGCGACGTGGAGGAGATGAGCATCGAGGAGACGGCGCACCAATTGTCGCTGAAGCCGGA
AACCGTGAAGACGCGCCTCCACCGAGCGCGGCGGCTGATGCGCCTTGCCGTCGAGAAGCAACTCGCGGGGACGTTTTCCG
AACTGTTCCCGTTCGACGGGGCGCGGTGCGAGCGGATGGCCGATCGAGTTATCGATAGGCTCCATGGCCTGGAAAGGCCA
CGCGAGCCAGGTTGA

Upstream 100 bases:

>100_bases
AACCGCGGGTTTGACGCCTTTGCCGGAAGCGGCGCTAAATGGCTTTCCGCAGGTCGAGGAGATCATCGACAACGGCATTG
TGCGGCGGGAGTGATAGGGA

Downstream 100 bases:

>100_bases
TGCCTGGTGTGACATCGGTTGCTTCGGTGACGGCCGATCAGGAGCCTCCGATGGCAACAATCCTCCAGTTGGGGTTGCTT
GAAGGAGCTTGAACCCAGGC

Product: RNA polymerase sigma factor

Products: NA

Alternate protein names: Sigma-W factor [H]

Number of amino acids: Translated: 244; Mature: 244

Protein sequence:

>244_residues
MRGLDIEMTMAHPKLDLERLSDEELVHLARQGGESAIRLLIKRNNRSLFRVARAVVRDDAEAEDIVQETYVSAFTKLDSF
RGHSRFSTWLTRIALNEALGRARKRWPAAELAELDMAEGCNGGSVIMFPTSLKPPGADAELARKQVRDLLETAVDELPDP
FRLVFILRDVEEMSIEETAHQLSLKPETVKTRLHRARRLMRLAVEKQLAGTFSELFPFDGARCERMADRVIDRLHGLERP
REPG

Sequences:

>Translated_244_residues
MRGLDIEMTMAHPKLDLERLSDEELVHLARQGGESAIRLLIKRNNRSLFRVARAVVRDDAEAEDIVQETYVSAFTKLDSF
RGHSRFSTWLTRIALNEALGRARKRWPAAELAELDMAEGCNGGSVIMFPTSLKPPGADAELARKQVRDLLETAVDELPDP
FRLVFILRDVEEMSIEETAHQLSLKPETVKTRLHRARRLMRLAVEKQLAGTFSELFPFDGARCERMADRVIDRLHGLERP
REPG
>Mature_244_residues
MRGLDIEMTMAHPKLDLERLSDEELVHLARQGGESAIRLLIKRNNRSLFRVARAVVRDDAEAEDIVQETYVSAFTKLDSF
RGHSRFSTWLTRIALNEALGRARKRWPAAELAELDMAEGCNGGSVIMFPTSLKPPGADAELARKQVRDLLETAVDELPDP
FRLVFILRDVEEMSIEETAHQLSLKPETVKTRLHRARRLMRLAVEKQLAGTFSELFPFDGARCERMADRVIDRLHGLERP
REPG

Specific function: Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. Sigma-W controls genes involved in transport processes and detoxification [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the sigma-70 factor family. ECF subfamily [H]

Homologues:

Organism=Escherichia coli, GI1788926, Length=187, Percent_Identity=31.5508021390374, Blast_Score=86, Evalue=2e-18,

Paralogues:

None

Copy number: <10 [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR014284
- InterPro:   IPR014294
- InterPro:   IPR000838
- InterPro:   IPR007627
- InterPro:   IPR013249
- InterPro:   IPR013325
- InterPro:   IPR013324
- InterPro:   IPR011991 [H]

Pfam domain/function: PF04542 Sigma70_r2; PF08281 Sigma70_r4_2 [H]

EC number: NA

Molecular weight: Translated: 27768; Mature: 27768

Theoretical pI: Translated: 6.81; Mature: 6.81

Prosite motif: PS01063 SIGMA70_ECF

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
3.3 %Met     (Translated Protein)
4.1 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
3.3 %Met     (Mature Protein)
4.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRGLDIEMTMAHPKLDLERLSDEELVHLARQGGESAIRLLIKRNNRSLFRVARAVVRDDA
CCCCCEEEECCCCCCHHHHCCHHHHHHHHHHCCHHHHHHHHHCCCHHHHHHHHHHHHCCC
EAEDIVQETYVSAFTKLDSFRGHSRFSTWLTRIALNEALGRARKRWPAAELAELDMAEGC
HHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHCCC
NGGSVIMFPTSLKPPGADAELARKQVRDLLETAVDELPDPFRLVFILRDVEEMSIEETAH
CCCEEEEEECCCCCCCCCHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHH
QLSLKPETVKTRLHRARRLMRLAVEKQLAGTFSELFPFDGARCERMADRVIDRLHGLERP
HHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHCCCCC
REPG
CCCC
>Mature Secondary Structure
MRGLDIEMTMAHPKLDLERLSDEELVHLARQGGESAIRLLIKRNNRSLFRVARAVVRDDA
CCCCCEEEECCCCCCHHHHCCHHHHHHHHHHCCHHHHHHHHHCCCHHHHHHHHHHHHCCC
EAEDIVQETYVSAFTKLDSFRGHSRFSTWLTRIALNEALGRARKRWPAAELAELDMAEGC
HHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHCCC
NGGSVIMFPTSLKPPGADAELARKQVRDLLETAVDELPDPFRLVFILRDVEEMSIEETAH
CCCEEEEEECCCCCCCCCHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHH
QLSLKPETVKTRLHRARRLMRLAVEKQLAGTFSELFPFDGARCERMADRVIDRLHGLERP
HHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHCCCCC
REPG
CCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9274029; 9384377; 12207695 [H]