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The map label for this gene is 110633532

Identifier: 110633532

GI number: 110633532

Start: 1288816

End: 1289313

Strand: Direct

Name: 110633532

Synonym: Meso_1179

Alternate gene names: NA

Gene position: 1288816-1289313 (Clockwise)

Preceding gene: 110633531

Following gene: 110633547

Centisome position: 29.21

GC content: 60.04

Gene sequence:

>498_bases
ATGACCGACCAAGTCTCTGACGAGGAATATTGTCTAAGATACAAGGAGACATGGGGGCCTGGTCCTCATGTTACCGCCGA
CGCAGTGGTTCTCTGCCGCGATGCGCGGGTCCTGCTTGTTCGCCGCGGCCGTCCGCCGGGGCAGGGCCTCTTGGCAATAC
CGGGTGGCTTCATCAATCTCGATGAGCGCCTTCTCGATGCAGCGCTTCGCGAATTGAAGGAAGAGACGGGCATCTCCGAT
GAGAAGGGCCTGTTATCGGATGAGACACTTCGAGCCGCGCTGCGGTCTAGCCAGGTCTTCGACGATCCGCACCGGTCGGG
CCGTGGACGAATCATTACAAACGCATTTCTCTTCCGGCTGCCAGGCACCTCTGAACGCTACCGGGTGGCGGGATCCGATG
ACGCGGCTGACGCAGGCTGGTATTCGCCGAACGAGCTTGAGCCGCGGCAGATGTTTGAAGACCATTGGCACATCCTCAAG
GCTTTGGGGGCGCTCTAA

Upstream 100 bases:

>100_bases
AAGATTCCGGATTCGGACGATTAGGGCCGGTTGGCGACTGGCGCTGAGCGCCACAGGGCCTGCTGCCCGATAGGCTGGCG
CTAAAGGGTGAGAGCTCGAA

Downstream 100 bases:

>100_bases
GGCATTTTGCAGCCTGGTGGATCACGTCGCACAGTTGCTGCGAAGGTTGGAGGGGCACACGCATAGCTGCGCATTCCCCG
CCAAGCATCGATCGCGGCGA

Product: NUDIX hydrolase

Products: NA

Alternate protein names: Nicotinamide-nucleotide adenylyltransferase; NAD(+) diphosphorylase; NAD(+) pyrophosphorylase; NMN adenylyltransferase; ADP compounds hydrolase [H]

Number of amino acids: Translated: 165; Mature: 164

Protein sequence:

>165_residues
MTDQVSDEEYCLRYKETWGPGPHVTADAVVLCRDARVLLVRRGRPPGQGLLAIPGGFINLDERLLDAALRELKEETGISD
EKGLLSDETLRAALRSSQVFDDPHRSGRGRIITNAFLFRLPGTSERYRVAGSDDAADAGWYSPNELEPRQMFEDHWHILK
ALGAL

Sequences:

>Translated_165_residues
MTDQVSDEEYCLRYKETWGPGPHVTADAVVLCRDARVLLVRRGRPPGQGLLAIPGGFINLDERLLDAALRELKEETGISD
EKGLLSDETLRAALRSSQVFDDPHRSGRGRIITNAFLFRLPGTSERYRVAGSDDAADAGWYSPNELEPRQMFEDHWHILK
ALGAL
>Mature_164_residues
TDQVSDEEYCLRYKETWGPGPHVTADAVVLCRDARVLLVRRGRPPGQGLLAIPGGFINLDERLLDAALRELKEETGISDE
KGLLSDETLRAALRSSQVFDDPHRSGRGRIITNAFLFRLPGTSERYRVAGSDDAADAGWYSPNELEPRQMFEDHWHILKA
LGAL

Specific function: The Nudix hydrolase domain is active on ADP-ribose, (2')-phospho-ADP-ribose, IDP-ribose and NADPH [H]

COG id: COG1051

COG function: function code F; ADP-ribose pyrophosphatase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Contains 1 nudix hydrolase domain [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004821
- InterPro:   IPR004820
- InterPro:   IPR020084
- InterPro:   IPR000086
- InterPro:   IPR015797
- InterPro:   IPR014729 [H]

Pfam domain/function: PF01467 CTP_transf_2; PF00293 NUDIX [H]

EC number: =2.7.7.1 [H]

Molecular weight: Translated: 18431; Mature: 18300

Theoretical pI: Translated: 5.08; Mature: 5.08

Prosite motif: PS00893 NUDIX

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
1.2 %Met     (Translated Protein)
2.4 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
0.6 %Met     (Mature Protein)
1.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTDQVSDEEYCLRYKETWGPGPHVTADAVVLCRDARVLLVRRGRPPGQGLLAIPGGFINL
CCCCCCCHHHHHHHHHCCCCCCCCCCCCEEEECCCEEEEEECCCCCCCCEEECCCCCCCH
DERLLDAALRELKEETGISDEKGLLSDETLRAALRSSQVFDDPHRSGRGRIITNAFLFRL
HHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHCCCCCCCCCCCCCEEEEEEEEEEC
PGTSERYRVAGSDDAADAGWYSPNELEPRQMFEDHWHILKALGAL
CCCCCCEEECCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure 
TDQVSDEEYCLRYKETWGPGPHVTADAVVLCRDARVLLVRRGRPPGQGLLAIPGGFINL
CCCCCCHHHHHHHHHCCCCCCCCCCCCEEEECCCEEEEEECCCCCCCCEEECCCCCCCH
DERLLDAALRELKEETGISDEKGLLSDETLRAALRSSQVFDDPHRSGRGRIITNAFLFRL
HHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHCCCCCCCCCCCCCEEEEEEEEEEC
PGTSERYRVAGSDDAADAGWYSPNELEPRQMFEDHWHILKALGAL
CCCCCCEEECCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8590279; 8905231; 10050763 [H]