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The map label for this gene is namA [H]

Identifier: 110633526

GI number: 110633526

Start: 1283277

End: 1284389

Strand: Direct

Name: namA [H]

Synonym: Meso_1173

Alternate gene names: 110633526

Gene position: 1283277-1284389 (Clockwise)

Preceding gene: 110633525

Following gene: 110633527

Centisome position: 29.08

GC content: 64.69

Gene sequence:

>1113_bases
ATGAGTTCCAAGCTTTTCACCCCGATGCGCGTCGGTTCGCTTCAATTGGACAACCGCATCGTGATCGCGCCGATGTGCCA
GTATTCGGCCGAGAATGGCTGCATGACCGACTGGCACACCATTCATCTCGGTGGCTTGGCCCTATCCGGCGCGGCATTGC
TCACCATCGAGGCGACCGCCGTAACACCCGAGGGCCGGATCTCCTACGCCGATGTCGGGCTTTACTCCGATGAAAATGAA
GCTGCGATGCGCCGTGTGCTGGAAACGGTCCGCCGCTGGTCGGATATGCCCATCGCCATCCAGCTTGCGCATGCGGGACG
AAAGGCGTCCTCCGAGATCCCATGGAAGGGGGGAGGGCAGATACGTCCCGGCCTTCCGGGCGGCTGGCAAACCGAGGCCC
CCTCGGCGGTGCCTTTCAAGGAGAGCGAGAATCCGCCGATCGCGCTTGATCGCGCCGGACTCGCCCGCGTGCGGGATGCC
TTTGCCGAAGCCACGCGGCGATCTGCCCGCCTCGGGCTAGACGCGGTGCAGATCCACGCGGCGCATGGCTATCTTCTGCA
TGAGTTTCTTTCGCCGCTGTCGAACCGCCGAGACGATGAATATGGCGGTTCGCTCGAAAACCGCATGCGCTTTCCCCTTG
AGGTCTTTGATGCGGTCCGTGCCGCCTTCCCGGCCGAGCAGCCGGTGACCGTGCGGGTTTCCGGTACGGACTGGGCCGAG
GGCGGCTGGACCATCGAGGATACCGTGGCATTCGCCAAGGCGCTCGAAGCGCGGGGGTGCGGCGCGATCCACGTTTCGAG
CGGCGGGCTTTCGGCCGCGCAGCGGATTCCGATCGGGCCCAACTACCAGGTTCCGCTCGCCCGGGCGGTCAAGGCTGCTG
TCCGCATGCCGGTCGTCGCCGTCGGGTTGATCACCGAATTCGAGCAGGCCGAAGCGATCATCGGCACGGGCGATGCTGAT
TTCGTCGCGCTTGCCCGCACCATTCTCTATGACCCGCACTGGCCCTGGCATGCCGCCGCCCATCTGGGTGCACGGGTCAA
GGCGCCCAAACAGTATCTCCGTTCCCAGCCGCGACGGTACAAGGACTTGTTCGCTGTTCGCGCGGATGATTGA

Upstream 100 bases:

>100_bases
TTGTGCCGCGAAGCTGCCTTATAATTGGCAGAGATTTTCCAATCGCGCCAAAGAGGCTTAAGGAAAGCTCCAGCCTTTTA
CCTCAAGGAAGTCCCGGAGA

Downstream 100 bases:

>100_bases
CCTTCTCTCGCGCGCACAACGCTTCGTCGGACAGGTCGGCCGCTAACGTGCATTCCCGCCGATATGACCGGCGTTCCCAT
CGGCATTTCCCGCATTATTC

Product: NADH:flavin oxidoreductase/NADH oxidase

Products: NA

Alternate protein names: Xenobiotic reductase [H]

Number of amino acids: Translated: 370; Mature: 369

Protein sequence:

>370_residues
MSSKLFTPMRVGSLQLDNRIVIAPMCQYSAENGCMTDWHTIHLGGLALSGAALLTIEATAVTPEGRISYADVGLYSDENE
AAMRRVLETVRRWSDMPIAIQLAHAGRKASSEIPWKGGGQIRPGLPGGWQTEAPSAVPFKESENPPIALDRAGLARVRDA
FAEATRRSARLGLDAVQIHAAHGYLLHEFLSPLSNRRDDEYGGSLENRMRFPLEVFDAVRAAFPAEQPVTVRVSGTDWAE
GGWTIEDTVAFAKALEARGCGAIHVSSGGLSAAQRIPIGPNYQVPLARAVKAAVRMPVVAVGLITEFEQAEAIIGTGDAD
FVALARTILYDPHWPWHAAAHLGARVKAPKQYLRSQPRRYKDLFAVRADD

Sequences:

>Translated_370_residues
MSSKLFTPMRVGSLQLDNRIVIAPMCQYSAENGCMTDWHTIHLGGLALSGAALLTIEATAVTPEGRISYADVGLYSDENE
AAMRRVLETVRRWSDMPIAIQLAHAGRKASSEIPWKGGGQIRPGLPGGWQTEAPSAVPFKESENPPIALDRAGLARVRDA
FAEATRRSARLGLDAVQIHAAHGYLLHEFLSPLSNRRDDEYGGSLENRMRFPLEVFDAVRAAFPAEQPVTVRVSGTDWAE
GGWTIEDTVAFAKALEARGCGAIHVSSGGLSAAQRIPIGPNYQVPLARAVKAAVRMPVVAVGLITEFEQAEAIIGTGDAD
FVALARTILYDPHWPWHAAAHLGARVKAPKQYLRSQPRRYKDLFAVRADD
>Mature_369_residues
SSKLFTPMRVGSLQLDNRIVIAPMCQYSAENGCMTDWHTIHLGGLALSGAALLTIEATAVTPEGRISYADVGLYSDENEA
AMRRVLETVRRWSDMPIAIQLAHAGRKASSEIPWKGGGQIRPGLPGGWQTEAPSAVPFKESENPPIALDRAGLARVRDAF
AEATRRSARLGLDAVQIHAAHGYLLHEFLSPLSNRRDDEYGGSLENRMRFPLEVFDAVRAAFPAEQPVTVRVSGTDWAEG
GWTIEDTVAFAKALEARGCGAIHVSSGGLSAAQRIPIGPNYQVPLARAVKAAVRMPVVAVGLITEFEQAEAIIGTGDADF
VALARTILYDPHWPWHAAAHLGARVKAPKQYLRSQPRRYKDLFAVRADD

Specific function: Catalyzes the reduction of the double bond of an array of alpha, beta-unsaturated aldehydes and ketones. It also reduces the nitro group of nitroester and nitroaromatic compounds. It could have a role in detoxification processes [H]

COG id: COG1902

COG function: function code C; NADH:flavin oxidoreductases, Old Yellow Enzyme family

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the NADH:flavin oxidoreductase/NADH oxidase family. NamA subfamily [H]

Homologues:

Organism=Escherichia coli, GI1787939, Length=346, Percent_Identity=31.2138728323699, Blast_Score=125, Evalue=3e-30,
Organism=Escherichia coli, GI1789463, Length=333, Percent_Identity=28.8288288288288, Blast_Score=111, Evalue=9e-26,
Organism=Caenorhabditis elegans, GI72001454, Length=205, Percent_Identity=32.6829268292683, Blast_Score=102, Evalue=4e-22,
Organism=Caenorhabditis elegans, GI17564188, Length=175, Percent_Identity=32, Blast_Score=101, Evalue=8e-22,
Organism=Caenorhabditis elegans, GI17540738, Length=203, Percent_Identity=33.4975369458128, Blast_Score=100, Evalue=9e-22,
Organism=Caenorhabditis elegans, GI17559804, Length=175, Percent_Identity=32.5714285714286, Blast_Score=99, Evalue=3e-21,
Organism=Caenorhabditis elegans, GI17559802, Length=116, Percent_Identity=37.0689655172414, Blast_Score=97, Evalue=2e-20,
Organism=Caenorhabditis elegans, GI17565138, Length=290, Percent_Identity=26.551724137931, Blast_Score=95, Evalue=7e-20,
Organism=Caenorhabditis elegans, GI17566914, Length=234, Percent_Identity=29.0598290598291, Blast_Score=81, Evalue=9e-16,
Organism=Saccharomyces cerevisiae, GI6325086, Length=240, Percent_Identity=28.75, Blast_Score=97, Evalue=3e-21,
Organism=Saccharomyces cerevisiae, GI6321973, Length=236, Percent_Identity=29.6610169491525, Blast_Score=97, Evalue=5e-21,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013785
- InterPro:   IPR001155 [H]

Pfam domain/function: PF00724 Oxidored_FMN [H]

EC number: =1.6.99.1 [H]

Molecular weight: Translated: 40179; Mature: 40048

Theoretical pI: Translated: 7.35; Mature: 7.35

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSSKLFTPMRVGSLQLDNRIVIAPMCQYSAENGCMTDWHTIHLGGLALSGAALLTIEATA
CCCCCCCCEECCCEEECCEEEEEEHHHCCCCCCCCCCCEEEEECCEEECCEEEEEEEEEE
VTPEGRISYADVGLYSDENEAAMRRVLETVRRWSDMPIAIQLAHAGRKASSEIPWKGGGQ
ECCCCCEEEEEECEECCCCHHHHHHHHHHHHHCCCCCEEEEEECCCCCCCCCCCCCCCCE
IRPGLPGGWQTEAPSAVPFKESENPPIALDRAGLARVRDAFAEATRRSARLGLDAVQIHA
ECCCCCCCCCCCCCCCCCCCCCCCCCEEECCHHHHHHHHHHHHHHHHHHHCCCCEEEEEE
AHGYLLHEFLSPLSNRRDDEYGGSLENRMRFPLEVFDAVRAAFPAEQPVTVRVSGTDWAE
HHHHHHHHHHHHHHCCCCCCCCCCHHHHCCCCHHHHHHHHHHCCCCCCEEEEECCCCCCC
GGWTIEDTVAFAKALEARGCGAIHVSSGGLSAAQRIPIGPNYQVPLARAVKAAVRMPVVA
CCCCHHHHHHHHHHHHHCCCCEEEEECCCCCHHHCCCCCCCCCCHHHHHHHHHHHCCHHH
VGLITEFEQAEAIIGTGDADFVALARTILYDPHWPWHAAAHLGARVKAPKQYLRSQPRRY
HHHHHHHHHCCEEEECCCHHHHHHHHHHHCCCCCCHHHHHHHCCCCCCHHHHHHCCCHHH
KDLFAVRADD
HHEEEEECCC
>Mature Secondary Structure 
SSKLFTPMRVGSLQLDNRIVIAPMCQYSAENGCMTDWHTIHLGGLALSGAALLTIEATA
CCCCCCCEECCCEEECCEEEEEEHHHCCCCCCCCCCCEEEEECCEEECCEEEEEEEEEE
VTPEGRISYADVGLYSDENEAAMRRVLETVRRWSDMPIAIQLAHAGRKASSEIPWKGGGQ
ECCCCCEEEEEECEECCCCHHHHHHHHHHHHHCCCCCEEEEEECCCCCCCCCCCCCCCCE
IRPGLPGGWQTEAPSAVPFKESENPPIALDRAGLARVRDAFAEATRRSARLGLDAVQIHA
ECCCCCCCCCCCCCCCCCCCCCCCCCEEECCHHHHHHHHHHHHHHHHHHHCCCCEEEEEE
AHGYLLHEFLSPLSNRRDDEYGGSLENRMRFPLEVFDAVRAAFPAEQPVTVRVSGTDWAE
HHHHHHHHHHHHHHCCCCCCCCCCHHHHCCCCHHHHHHHHHHCCCCCCEEEEECCCCCCC
GGWTIEDTVAFAKALEARGCGAIHVSSGGLSAAQRIPIGPNYQVPLARAVKAAVRMPVVA
CCCCHHHHHHHHHHHHHCCCCEEEEECCCCCHHHCCCCCCCCCCHHHHHHHHHHHCCHHH
VGLITEFEQAEAIIGTGDADFVALARTILYDPHWPWHAAAHLGARVKAPKQYLRSQPRRY
HHHHHHHHHCCEEEECCCHHHHHHHHHHHCCCCCCHHHHHHHCCCCCCHHHHHHCCCHHH
KDLFAVRADD
HHEEEEECCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA