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The map label for this gene is ctaA

Identifier: 110633513

GI number: 110633513

Start: 1269458

End: 1270543

Strand: Direct

Name: ctaA

Synonym: Meso_1160

Alternate gene names: 110633513

Gene position: 1269458-1270543 (Clockwise)

Preceding gene: 110633510

Following gene: 110633518

Centisome position: 28.77

GC content: 62.8

Gene sequence:

>1086_bases
ATGGTCGCCGCTACCGAGTTTCCTGTTTCTCCTATGCTGACCGATGCCGCACGCCGCAACCGCCTCTGGGTTCGGATCTG
GCTTTACTGCGTCATCGTCACCCTCTTCGCGATAGTGCTCGTCGGCGGTGCCACGCGCCTCACCGATTCCGGCCTTTCCA
TCACGGAGTGGAAGCCTATTCACGGAGTCATCCCGCCGCTTGGCGAGGCGGAATGGGCGGAAGAGTTCGCCAGATATCAG
CAGATCCCGGAATATGAGCAGATCAACAAGGGCATGAGCCTGGAGGAGTTCAAGGGCATCTTCTGGTGGGAGTGGGCGCA
CCGCTTGCTCGCGCGCGGCGTGGGCTTCGTCTTCGCCCTGCCGCTCCTCTTCTTCTGGGTGACCGGTCGGCTGGAACGCC
ACCTAAAGCCGAAGCTCCTGGGCATCCTGGCCTTGGGCGGGCTGCAGGGGGCAGTGGGATGGTGGATGGTGGCCTCCGGG
CTTTCCGAGCGCGTTGATGTCAGCCAGTATCGGCTGGCCACGCACCTCACCATTGCCTGCCTCATCTTTAATGCCACCAT
GGCGGTGGCGCGCGGCCTGGCACCGCACAGCGGGAAACCCGCGCTCGATTCGACCCGCCGCTTCGCCTTCTGGCTCGTCG
TCGCCGTGCTCGTGCAGATCTATCTTGGAGGGCTTGTCGCGGGGCTGGACGCCGGCATGGCCTATAATACCTGGCCGCTC
ATGGATGGGGCCTTGGTACCCCAGGGCCTGTTCGAGCATCGTCCAGCTTGGGTGAACCTCTTCGAAAATCCCAAAACCGT
GCAGTTTGTGCACCGTCTTGGGGCCTATGTCGTCCTCCTGCTGGCTTTGTGGCATGCGATTGCCACTTTGCGCGCCGAGC
CCGACTCAACCCATGCGCGCAGGGCTGTCCTTCTCTTCCTTTTGGTATGCGTGCAGGCAGCGATCGGAATCGCGACGCTT
CTCATGGTGGTGCCAATGGATGTGGCGCTTGCCCATCAGGCGATGGCGTTGATCGTGCTTGGCTTTGCCACCGCCCACTG
GCGTGCAACCAGGGGCGCCTATCCGTTCATGCAGGCGGCCGCTTAG

Upstream 100 bases:

>100_bases
CTATAATGCCGCATCCCGCAGGGCGACCGCATGTCGCGCGGGGAAAACTTGCAAGCGGGGCGACTTTGGTCCACCTAACG
GCAAACCGCCGGACACACAA

Downstream 100 bases:

>100_bases
TTCTTTAGCAGCAGAATTCGGCTTTCGCCGCTGAGGCGCATACCGACGAAGCGGGCGCGAGCGGCCGCGGAGCATTCGTC
AGCGGAGCCCGGAAAGCATC

Product: cytochrome oxidase assembly

Products: NA

Alternate protein names: HAS; Cytochrome aa3-controlling protein

Number of amino acids: Translated: 361; Mature: 361

Protein sequence:

>361_residues
MVAATEFPVSPMLTDAARRNRLWVRIWLYCVIVTLFAIVLVGGATRLTDSGLSITEWKPIHGVIPPLGEAEWAEEFARYQ
QIPEYEQINKGMSLEEFKGIFWWEWAHRLLARGVGFVFALPLLFFWVTGRLERHLKPKLLGILALGGLQGAVGWWMVASG
LSERVDVSQYRLATHLTIACLIFNATMAVARGLAPHSGKPALDSTRRFAFWLVVAVLVQIYLGGLVAGLDAGMAYNTWPL
MDGALVPQGLFEHRPAWVNLFENPKTVQFVHRLGAYVVLLLALWHAIATLRAEPDSTHARRAVLLFLLVCVQAAIGIATL
LMVVPMDVALAHQAMALIVLGFATAHWRATRGAYPFMQAAA

Sequences:

>Translated_361_residues
MVAATEFPVSPMLTDAARRNRLWVRIWLYCVIVTLFAIVLVGGATRLTDSGLSITEWKPIHGVIPPLGEAEWAEEFARYQ
QIPEYEQINKGMSLEEFKGIFWWEWAHRLLARGVGFVFALPLLFFWVTGRLERHLKPKLLGILALGGLQGAVGWWMVASG
LSERVDVSQYRLATHLTIACLIFNATMAVARGLAPHSGKPALDSTRRFAFWLVVAVLVQIYLGGLVAGLDAGMAYNTWPL
MDGALVPQGLFEHRPAWVNLFENPKTVQFVHRLGAYVVLLLALWHAIATLRAEPDSTHARRAVLLFLLVCVQAAIGIATL
LMVVPMDVALAHQAMALIVLGFATAHWRATRGAYPFMQAAA
>Mature_361_residues
MVAATEFPVSPMLTDAARRNRLWVRIWLYCVIVTLFAIVLVGGATRLTDSGLSITEWKPIHGVIPPLGEAEWAEEFARYQ
QIPEYEQINKGMSLEEFKGIFWWEWAHRLLARGVGFVFALPLLFFWVTGRLERHLKPKLLGILALGGLQGAVGWWMVASG
LSERVDVSQYRLATHLTIACLIFNATMAVARGLAPHSGKPALDSTRRFAFWLVVAVLVQIYLGGLVAGLDAGMAYNTWPL
MDGALVPQGLFEHRPAWVNLFENPKTVQFVHRLGAYVVLLLALWHAIATLRAEPDSTHARRAVLLFLLVCVQAAIGIATL
LMVVPMDVALAHQAMALIVLGFATAHWRATRGAYPFMQAAA

Specific function: Catalyzes the oxidation of the C8 methyl side group on heme O porphyrin ring into a formyl group

COG id: COG1612

COG function: function code O; Uncharacterized protein required for cytochrome oxidase assembly

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the COX15/CtaA family. Type 2 subfamily

Homologues:

Organism=Homo sapiens, GI17921985, Length=325, Percent_Identity=40.6153846153846, Blast_Score=216, Evalue=3e-56,
Organism=Homo sapiens, GI17921987, Length=257, Percent_Identity=42.4124513618677, Blast_Score=194, Evalue=9e-50,
Organism=Caenorhabditis elegans, GI17536069, Length=350, Percent_Identity=36.2857142857143, Blast_Score=202, Evalue=2e-52,
Organism=Saccharomyces cerevisiae, GI6320989, Length=379, Percent_Identity=39.0501319261214, Blast_Score=216, Evalue=4e-57,
Organism=Drosophila melanogaster, GI19922860, Length=357, Percent_Identity=37.8151260504202, Blast_Score=203, Evalue=1e-52,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): CTAA_MESSB (Q11J69)

Other databases:

- EMBL:   CP000390
- RefSeq:   YP_673721.1
- STRING:   Q11J69
- GeneID:   4180751
- GenomeReviews:   CP000390_GR
- KEGG:   mes:Meso_1160
- NMPDR:   fig|266779.1.peg.2425
- eggNOG:   COG1612
- HOGENOM:   HBG628966
- OMA:   GLSIVEW
- PhylomeDB:   Q11J69
- ProtClustDB:   CLSK2747580
- BioCyc:   MSP266779:MESO_1160-MONOMER
- HAMAP:   MF_01665
- InterPro:   IPR003780

Pfam domain/function: PF02628 COX15-CtaA

EC number: NA

Molecular weight: Translated: 40000; Mature: 40000

Theoretical pI: Translated: 9.37; Mature: 9.37

Prosite motif: NA

Important sites: BINDING 332-332

Signals:

None

Transmembrane regions:

HASH(0x13d694b8)-; HASH(0x17e4320c)-; HASH(0x18f5f650)-; HASH(0x122cfa1c)-; HASH(0x18eb9ecc)-; HASH(0x18e49b54)-; HASH(0x18e6eeac)-; HASH(0x17c4f3a0)-;

Cys/Met content:

0.8 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
3.9 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
3.0 %Met     (Mature Protein)
3.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MVAATEFPVSPMLTDAARRNRLWVRIWLYCVIVTLFAIVLVGGATRLTDSGLSITEWKPI
CCCCCCCCCCHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHCCCHHCCCCCCCCCCCCCC
HGVIPPLGEAEWAEEFARYQQIPEYEQINKGMSLEEFKGIFWWEWAHRLLARGVGFVFAL
CCCCCCCCCHHHHHHHHHHHCCCCHHHHHCCCCHHHHCCHHHHHHHHHHHHHHHHHHHHH
PLLFFWVTGRLERHLKPKLLGILALGGLQGAVGWWMVASGLSERVDVSQYRLATHLTIAC
HHHHHHHHHHHHHHCCHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LIFNATMAVARGLAPHSGKPALDSTRRFAFWLVVAVLVQIYLGGLVAGLDAGMAYNTWPL
HHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCC
MDGALVPQGLFEHRPAWVNLFENPKTVQFVHRLGAYVVLLLALWHAIATLRAEPDSTHAR
CCCCCCCCHHHHCCCCCEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHH
RAVLLFLLVCVQAAIGIATLLMVVPMDVALAHQAMALIVLGFATAHWRATRGAYPFMQAA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHC
A
H
>Mature Secondary Structure
MVAATEFPVSPMLTDAARRNRLWVRIWLYCVIVTLFAIVLVGGATRLTDSGLSITEWKPI
CCCCCCCCCCHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHCCCHHCCCCCCCCCCCCCC
HGVIPPLGEAEWAEEFARYQQIPEYEQINKGMSLEEFKGIFWWEWAHRLLARGVGFVFAL
CCCCCCCCCHHHHHHHHHHHCCCCHHHHHCCCCHHHHCCHHHHHHHHHHHHHHHHHHHHH
PLLFFWVTGRLERHLKPKLLGILALGGLQGAVGWWMVASGLSERVDVSQYRLATHLTIAC
HHHHHHHHHHHHHHCCHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LIFNATMAVARGLAPHSGKPALDSTRRFAFWLVVAVLVQIYLGGLVAGLDAGMAYNTWPL
HHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCC
MDGALVPQGLFEHRPAWVNLFENPKTVQFVHRLGAYVVLLLALWHAIATLRAEPDSTHAR
CCCCCCCCHHHHCCCCCEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHH
RAVLLFLLVCVQAAIGIATLLMVVPMDVALAHQAMALIVLGFATAHWRATRGAYPFMQAA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHC
A
H

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: NA