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The map label for this gene is hppA [H]

Identifier: 110633494

GI number: 110633494

Start: 1247805

End: 1249943

Strand: Direct

Name: hppA [H]

Synonym: Meso_1141

Alternate gene names: 110633494

Gene position: 1247805-1249943 (Clockwise)

Preceding gene: 110633493

Following gene: 110633496

Centisome position: 28.28

GC content: 62.32

Gene sequence:

>2139_bases
ATGACCATGCTTTACGTTGTCATCGCCTGCGGCCTGCTTTCTGTCCTTTATGCCATCTGGGCTACACAATCGGTGCTCGC
CGCCGATCAGGGCAATGCACGCATGCAGGAAATCGCCGGTGCCATTCGGGAGGGCGCACAGGCTTATCTCACTCGGCAAT
ATACGACCATCGCCATTGTCGGTGTCGTCGTTTTCCTCCTTGCCTGGTGGCTGCTGAATGCCGCCGCGGCGATCGGTTTT
CTCATCGGTGCCGTGCTCTCGGGGGCTGCCGGCTTCATCGGCATGCATGTTTCCGTCCGCGCCAATGTGCGCACGGCGCA
GGCGGCCTCGAACAGTCTTTCCGCCGGGCTCGAGATCGCCTTCAAATCGGGCGCCATCACCGGCATGCTTGTGGCTGGTC
TCGCGCTGCTCGGCGTCTCCGTCTATTATTGGGTGCTGATCGGCCCCATGGGCTACGGGCCTGCGGATCGCGGCGTTATC
GACGCGCTGGTTGCGCTTGGGTTCGGCGCCTCCCTCATCTCCATTTTCGCCCGTCTGGGCGGCGGCATCTTCACCAAGGG
TGCCGATGTTGGTGGCGACCTTGTGGGCAAGGTGGAAGCGGGCATTCCGGAAGACGATCCGCGCAATCCGGCTACCATCG
CCGACAATGTCGGTGACAATGTGGGTGACTGCGCCGGCATGGCTGCCGACCTGTTCGAGACCTATGCGGTGACGGTCGTT
GCCACCATGGTTCTTGGCGCCATTTTCTTCGGCGGAAGCGAGATTTTGGGGAGCGTGATGCTCTACCCGCTCGCCATATG
CGGCGCCTGCATCATCACATCCATCATCGGCACCTTCTTCGTGAAGCTTGGCACGAACAACTCCATTATGGGCGCGCTCT
ACAGGGGTTTGATCGTAACCGGCCTGCTCACGATCCTCGGCATCGGTGCCGCCACGTCGCTTACGGTGGGATGGGGCGAC
CTCGGAACAGTCAACGGCATCACCGTCAACGGCACGAGCCTGTTCGTCTGCGGCCTGATCGGCCTCGTCGTGACCGGCCT
GATCGTGGTGATTACGGAATACTACACCGGCACCAACAAGCGCCCGGTGAATTCGATCGCGCAGGCCTCCGTCACGGGCC
ACGGCACGAATGTGATCCAGGGGCTTGCGGTGTCGCTGGAAGCGACCGCGCTTCCCGCCATCGTGATCGTGGGCGGCATT
ATCGCCACCTACCAGCTCGGCGGCCTTTACGGCACGGCGATTGCCGTCACCACCATGCTTGGGCTCGCCGGCATGATCGT
GGCGCTCGACGCTTTCGGTCCGGTGACGGACAATGCCGGCGGCATCGCCGAAATGTCGGGCCTGCCGCCTGAGGTGCGCC
AGTCCACCGATGCGCTCGATGCTGTCGGCAACACCACCAAGGCGGTGACCAAGGGTTATGCGATCGGCTCGGCAGGTCTC
GGCGCGCTGGTTCTTTTCGCGGCCTATTCCTACGACCTGCAATATTTTGCCGCCAATGCGACCGAGTTCCCCTATTTCGC
GGATATCGGCGACATCTCCTTCTCCCTGTCCAACCCCTATGTGGTGGCCGGCCTGATTTTCGGCGGCCTCATCCCCTATC
TCTTCGGCGGTATCGCCATGACGGCGGTGGGGCGTGCTGCGGGGTCGATCGTGGAAGAGGTGCGCAAGCAGTTCCGCGAC
GATCCCGGCATCATGCAGGGTACGAGCAAACCAAACTACGCGCGCGCCGTGGATATGCTCACAAAGGCGGCGATCCGCGA
AATGATCATTCCGTCATTGCTGCCGGTGCTGGCGCCGCTGGTCGTTTATTTCGGCGTGCTGCTCATTTCAGGCTCGAAGG
CCTCGGCCTTCGCTGCGCTCGGTGCCTCGCTCCTGGGCGTGATCGTCAACGGCCTCTTCGTCGCCATCTCCATGACTTCG
GGCGGCGGCGCATGGGACAACGCCAAAAAGAGCTTCGAGGACGGTTTCGTCGACAAGGACGGTGTGAAGCACATGAAGGG
GTCCGACGCCCATAAAGCATCGGTGACGGGCGACACCGTGGGCGATCCTTACAAGGACACCGCCGGCCCCGCCGTGAATC
CGGCCATCAAGATCACCAACATCATGGCATTGCTGCTGCTCGCCGTACTCGCGCACTAG

Upstream 100 bases:

>100_bases
TCACAAAGTCGCGCCCTGGGCTGCGGCATTTCTTCGCTGCGGCCTTTCTCCAGGCCCGGGGAGGGGTTCCGGCGGGCCGA
AATCAAGGGATTGTTTTGGC

Downstream 100 bases:

>100_bases
CGCTTTAGGCAAAGAGCATCAAAAGCAAAAAGGCCCGCATTTCTGCGGGCCTTTTTCGTGGGATCGATCGCTCTTTACTG
ACCGCCGCCGCCAGCGGCGC

Product: membrane-bound proton-translocating pyrophosphatase

Products: NA

Alternate protein names: Membrane-bound proton-translocating pyrophosphatase; Pyrophosphate-energized inorganic pyrophosphatase; H(+)-PPase [H]

Number of amino acids: Translated: 712; Mature: 711

Protein sequence:

>712_residues
MTMLYVVIACGLLSVLYAIWATQSVLAADQGNARMQEIAGAIREGAQAYLTRQYTTIAIVGVVVFLLAWWLLNAAAAIGF
LIGAVLSGAAGFIGMHVSVRANVRTAQAASNSLSAGLEIAFKSGAITGMLVAGLALLGVSVYYWVLIGPMGYGPADRGVI
DALVALGFGASLISIFARLGGGIFTKGADVGGDLVGKVEAGIPEDDPRNPATIADNVGDNVGDCAGMAADLFETYAVTVV
ATMVLGAIFFGGSEILGSVMLYPLAICGACIITSIIGTFFVKLGTNNSIMGALYRGLIVTGLLTILGIGAATSLTVGWGD
LGTVNGITVNGTSLFVCGLIGLVVTGLIVVITEYYTGTNKRPVNSIAQASVTGHGTNVIQGLAVSLEATALPAIVIVGGI
IATYQLGGLYGTAIAVTTMLGLAGMIVALDAFGPVTDNAGGIAEMSGLPPEVRQSTDALDAVGNTTKAVTKGYAIGSAGL
GALVLFAAYSYDLQYFAANATEFPYFADIGDISFSLSNPYVVAGLIFGGLIPYLFGGIAMTAVGRAAGSIVEEVRKQFRD
DPGIMQGTSKPNYARAVDMLTKAAIREMIIPSLLPVLAPLVVYFGVLLISGSKASAFAALGASLLGVIVNGLFVAISMTS
GGGAWDNAKKSFEDGFVDKDGVKHMKGSDAHKASVTGDTVGDPYKDTAGPAVNPAIKITNIMALLLLAVLAH

Sequences:

>Translated_712_residues
MTMLYVVIACGLLSVLYAIWATQSVLAADQGNARMQEIAGAIREGAQAYLTRQYTTIAIVGVVVFLLAWWLLNAAAAIGF
LIGAVLSGAAGFIGMHVSVRANVRTAQAASNSLSAGLEIAFKSGAITGMLVAGLALLGVSVYYWVLIGPMGYGPADRGVI
DALVALGFGASLISIFARLGGGIFTKGADVGGDLVGKVEAGIPEDDPRNPATIADNVGDNVGDCAGMAADLFETYAVTVV
ATMVLGAIFFGGSEILGSVMLYPLAICGACIITSIIGTFFVKLGTNNSIMGALYRGLIVTGLLTILGIGAATSLTVGWGD
LGTVNGITVNGTSLFVCGLIGLVVTGLIVVITEYYTGTNKRPVNSIAQASVTGHGTNVIQGLAVSLEATALPAIVIVGGI
IATYQLGGLYGTAIAVTTMLGLAGMIVALDAFGPVTDNAGGIAEMSGLPPEVRQSTDALDAVGNTTKAVTKGYAIGSAGL
GALVLFAAYSYDLQYFAANATEFPYFADIGDISFSLSNPYVVAGLIFGGLIPYLFGGIAMTAVGRAAGSIVEEVRKQFRD
DPGIMQGTSKPNYARAVDMLTKAAIREMIIPSLLPVLAPLVVYFGVLLISGSKASAFAALGASLLGVIVNGLFVAISMTS
GGGAWDNAKKSFEDGFVDKDGVKHMKGSDAHKASVTGDTVGDPYKDTAGPAVNPAIKITNIMALLLLAVLAH
>Mature_711_residues
TMLYVVIACGLLSVLYAIWATQSVLAADQGNARMQEIAGAIREGAQAYLTRQYTTIAIVGVVVFLLAWWLLNAAAAIGFL
IGAVLSGAAGFIGMHVSVRANVRTAQAASNSLSAGLEIAFKSGAITGMLVAGLALLGVSVYYWVLIGPMGYGPADRGVID
ALVALGFGASLISIFARLGGGIFTKGADVGGDLVGKVEAGIPEDDPRNPATIADNVGDNVGDCAGMAADLFETYAVTVVA
TMVLGAIFFGGSEILGSVMLYPLAICGACIITSIIGTFFVKLGTNNSIMGALYRGLIVTGLLTILGIGAATSLTVGWGDL
GTVNGITVNGTSLFVCGLIGLVVTGLIVVITEYYTGTNKRPVNSIAQASVTGHGTNVIQGLAVSLEATALPAIVIVGGII
ATYQLGGLYGTAIAVTTMLGLAGMIVALDAFGPVTDNAGGIAEMSGLPPEVRQSTDALDAVGNTTKAVTKGYAIGSAGLG
ALVLFAAYSYDLQYFAANATEFPYFADIGDISFSLSNPYVVAGLIFGGLIPYLFGGIAMTAVGRAAGSIVEEVRKQFRDD
PGIMQGTSKPNYARAVDMLTKAAIREMIIPSLLPVLAPLVVYFGVLLISGSKASAFAALGASLLGVIVNGLFVAISMTSG
GGAWDNAKKSFEDGFVDKDGVKHMKGSDAHKASVTGDTVGDPYKDTAGPAVNPAIKITNIMALLLLAVLAH

Specific function: Proton pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for proton movement across the membrane. Generates a proton motive force [H]

COG id: COG3808

COG function: function code C; Inorganic pyrophosphatase

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the H(+)-translocating pyrophosphatase (TC 3.A.10) family. K(+)-insensitive subfamily [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004131 [H]

Pfam domain/function: PF03030 H_PPase [H]

EC number: =3.6.1.1 [H]

Molecular weight: Translated: 72566; Mature: 72435

Theoretical pI: Translated: 4.80; Mature: 4.80

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTMLYVVIACGLLSVLYAIWATQSVLAADQGNARMQEIAGAIREGAQAYLTRQYTTIAIV
CHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHH
GVVVFLLAWWLLNAAAAIGFLIGAVLSGAAGFIGMHVSVRANVRTAQAASNSLSAGLEIA
HHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHEEEEEEEECCHHHHHHCCHHCCCEEEE
FKSGAITGMLVAGLALLGVSVYYWVLIGPMGYGPADRGVIDALVALGFGASLISIFARLG
ECCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHCCHHHHHHHHHHC
GGIFTKGADVGGDLVGKVEAGIPEDDPRNPATIADNVGDNVGDCAGMAADLFETYAVTVV
CCEEECCCCCCCHHHHHHCCCCCCCCCCCCCCHHHHCCCCHHHHHHHHHHHHHHHHHHHH
ATMVLGAIFFGGSEILGSVMLYPLAICGACIITSIIGTFFVKLGTNNSIMGALYRGLIVT
HHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHH
GLLTILGIGAATSLTVGWGDLGTVNGITVNGTSLFVCGLIGLVVTGLIVVITEYYTGTNK
HHHHHHHCCCHHEEEECCCCCCCCCCEEECCHHHHHHHHHHHHHHHHHHHHHHHHCCCCC
RPVNSIAQASVTGHGTNVIQGLAVSLEATALPAIVIVGGIIATYQLGGLYGTAIAVTTML
CCHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHH
GLAGMIVALDAFGPVTDNAGGIAEMSGLPPEVRQSTDALDAVGNTTKAVTKGYAIGSAGL
HHHHHHHHHHCCCCCCCCCCCCHHHCCCCHHHHHHHHHHHHHCCHHHHHHHCCCCCCCHH
GALVLFAAYSYDLQYFAANATEFPYFADIGDISFSLSNPYVVAGLIFGGLIPYLFGGIAM
HHHHHHHHHHHHHHHEECCCCCCCCEECCCCEEEECCCCHHHHHHHHHHHHHHHHHHHHH
TAVGRAAGSIVEEVRKQFRDDPGIMQGTSKPNYARAVDMLTKAAIREMIIPSLLPVLAPL
HHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
VVYFGVLLISGSKASAFAALGASLLGVIVNGLFVAISMTSGGGAWDNAKKSFEDGFVDKD
HHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHEEEEECCCCCCCCHHHHHHHCCCCCCC
GVKHMKGSDAHKASVTGDTVGDPYKDTAGPAVNPAIKITNIMALLLLAVLAH
CHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure 
TMLYVVIACGLLSVLYAIWATQSVLAADQGNARMQEIAGAIREGAQAYLTRQYTTIAIV
HHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHH
GVVVFLLAWWLLNAAAAIGFLIGAVLSGAAGFIGMHVSVRANVRTAQAASNSLSAGLEIA
HHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHEEEEEEEECCHHHHHHCCHHCCCEEEE
FKSGAITGMLVAGLALLGVSVYYWVLIGPMGYGPADRGVIDALVALGFGASLISIFARLG
ECCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHCCHHHHHHHHHHC
GGIFTKGADVGGDLVGKVEAGIPEDDPRNPATIADNVGDNVGDCAGMAADLFETYAVTVV
CCEEECCCCCCCHHHHHHCCCCCCCCCCCCCCHHHHCCCCHHHHHHHHHHHHHHHHHHHH
ATMVLGAIFFGGSEILGSVMLYPLAICGACIITSIIGTFFVKLGTNNSIMGALYRGLIVT
HHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHH
GLLTILGIGAATSLTVGWGDLGTVNGITVNGTSLFVCGLIGLVVTGLIVVITEYYTGTNK
HHHHHHHCCCHHEEEECCCCCCCCCCEEECCHHHHHHHHHHHHHHHHHHHHHHHHCCCCC
RPVNSIAQASVTGHGTNVIQGLAVSLEATALPAIVIVGGIIATYQLGGLYGTAIAVTTML
CCHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHH
GLAGMIVALDAFGPVTDNAGGIAEMSGLPPEVRQSTDALDAVGNTTKAVTKGYAIGSAGL
HHHHHHHHHHCCCCCCCCCCCCHHHCCCCHHHHHHHHHHHHHCCHHHHHHHCCCCCCCHH
GALVLFAAYSYDLQYFAANATEFPYFADIGDISFSLSNPYVVAGLIFGGLIPYLFGGIAM
HHHHHHHHHHHHHHHEECCCCCCCCEECCCCEEEECCCCHHHHHHHHHHHHHHHHHHHHH
TAVGRAAGSIVEEVRKQFRDDPGIMQGTSKPNYARAVDMLTKAAIREMIIPSLLPVLAPL
HHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
VVYFGVLLISGSKASAFAALGASLLGVIVNGLFVAISMTSGGGAWDNAKKSFEDGFVDKD
HHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHEEEEECCCCCCCCHHHHHHHCCCCCCC
GVKHMKGSDAHKASVTGDTVGDPYKDTAGPAVNPAIKITNIMALLLLAVLAH
CHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 11214968 [H]