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The map label for this gene is aapQ [H]

Identifier: 110633467

GI number: 110633467

Start: 1217028

End: 1218218

Strand: Direct

Name: aapQ [H]

Synonym: Meso_1114

Alternate gene names: 110633467

Gene position: 1217028-1218218 (Clockwise)

Preceding gene: 110633466

Following gene: 110633468

Centisome position: 27.58

GC content: 60.2

Gene sequence:

>1191_bases
ATGACGATCGATACCTCGAGTATTTCGTTGTCGCATGAGCGCATAGGGCTCATGCGAAACCCCAGAACGCGTGGCCTCAT
TATCCAGACCGTGTTGATCATCGCCATTTTGGCCTTTGCCGCATGGCTCATCAACAATACGGTGAACAACCTAACGCGCG
CGAATATCGCCTCCGGATTCGACTTTCTTTCCGCCCGCGCCGGTTTCGATATCGGGCAAGTGCCGATCGCTTATTCCGCC
AATTCCAGTTATGGGCGCGCATTGCTGGTGGGCATCACCAACACCGTGATTGTCGCGGGGGCCGGTATCGTGCTTGCCAC
GATCGTTGGTTTCGTCATCGGCATCGGCCGCCTGTCGCGCAATTATCTCGTGCGGGGCCTGAGCACCATTTATGTCGAGA
CGTTCCGCAACGTGCCGCCGCTTCTGGTGATCCTGTTCTGGTATTTCGGCGTCCTTTCCGTGCTGCCATTGCCGAGGGAA
GCGCTGGAACTGCCATTCGGTGCATATCTCTCAAACCGTGGCCTGCAGATGCCTGCCGCGCGGTTTGAGCCGCTGGCGGT
GTGGACGCTTGCCGCCTTCGCACTCGGTATCGCCGCTGCAGTCCTCCTGTCGCGGCGGAATAAGCTTCGCCAGATGCGGA
CGGGTGAGCGGCAATCGATTCTGTGGCCGGTTCTCGGCCTTATCTTCGGGTTGCCGCTGATCGTTTTTGTGGTCACCGGC
CTGCCTGTCAGCTTCGAGGCGCCTCAAGCAACGCGTTTCAACCTGGTGGGCGGATGGCAGATCAGGCCGGAATTCCTGTC
GCTTTTCCTGGCGCTCTCCTTCTACACCGCCGCTTTTATCGCGGAGATTATCCGCGCCGGCATTCTGGCCGTTTCCAGAG
GGCAGACGGAAGCAGCATCGGCGCTGGGGCTCACGCGGCGGCAATCGCTTAGGCTCGTTGTTGTCCCGCAGGCCTTCCGT
GTCGTGATCCCGCCACTGACGAGCCAATATCTCAACCTGACCAAGAATTCCTCGCTCGGTCTGGCGGTCGGCTATCCCGA
ACTCGTCGCGGTCGGCTCGACCGTATTGAACCAGACCGGCCAGTCCGTGGAGGTCGTGGCGATCTGGATGGTTGTCTATC
TGGGGCTGAGCGTCGCCACCGCGGCCTTCATGAACTGGTTCAACGCCCGCGTGGCGCTTGTGGAGCGATAG

Upstream 100 bases:

>100_bases
GCACAAGCCGCGGCGCGGCTGAGTTCGCGGCTTCCCTGTAAGCCAAAGCGTGAGCCGCCGTTTCTTTTGGATGGCTCACG
ACTCGGCGTAGGCAAATCGC

Downstream 100 bases:

>100_bases
GGGGCCGCGCGATGGAAGAACAGGTAGCAGCCTATGTCGCCCGTGAGCAGAAACAGCCGCTGCCGCCGCCTCCGAGCGAA
TTCGGCATCGTGGCCACTTT

Product: polar amino acid ABC transporter, inner membrane subunit

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 396; Mature: 395

Protein sequence:

>396_residues
MTIDTSSISLSHERIGLMRNPRTRGLIIQTVLIIAILAFAAWLINNTVNNLTRANIASGFDFLSARAGFDIGQVPIAYSA
NSSYGRALLVGITNTVIVAGAGIVLATIVGFVIGIGRLSRNYLVRGLSTIYVETFRNVPPLLVILFWYFGVLSVLPLPRE
ALELPFGAYLSNRGLQMPAARFEPLAVWTLAAFALGIAAAVLLSRRNKLRQMRTGERQSILWPVLGLIFGLPLIVFVVTG
LPVSFEAPQATRFNLVGGWQIRPEFLSLFLALSFYTAAFIAEIIRAGILAVSRGQTEAASALGLTRRQSLRLVVVPQAFR
VVIPPLTSQYLNLTKNSSLGLAVGYPELVAVGSTVLNQTGQSVEVVAIWMVVYLGLSVATAAFMNWFNARVALVER

Sequences:

>Translated_396_residues
MTIDTSSISLSHERIGLMRNPRTRGLIIQTVLIIAILAFAAWLINNTVNNLTRANIASGFDFLSARAGFDIGQVPIAYSA
NSSYGRALLVGITNTVIVAGAGIVLATIVGFVIGIGRLSRNYLVRGLSTIYVETFRNVPPLLVILFWYFGVLSVLPLPRE
ALELPFGAYLSNRGLQMPAARFEPLAVWTLAAFALGIAAAVLLSRRNKLRQMRTGERQSILWPVLGLIFGLPLIVFVVTG
LPVSFEAPQATRFNLVGGWQIRPEFLSLFLALSFYTAAFIAEIIRAGILAVSRGQTEAASALGLTRRQSLRLVVVPQAFR
VVIPPLTSQYLNLTKNSSLGLAVGYPELVAVGSTVLNQTGQSVEVVAIWMVVYLGLSVATAAFMNWFNARVALVER
>Mature_395_residues
TIDTSSISLSHERIGLMRNPRTRGLIIQTVLIIAILAFAAWLINNTVNNLTRANIASGFDFLSARAGFDIGQVPIAYSAN
SSYGRALLVGITNTVIVAGAGIVLATIVGFVIGIGRLSRNYLVRGLSTIYVETFRNVPPLLVILFWYFGVLSVLPLPREA
LELPFGAYLSNRGLQMPAARFEPLAVWTLAAFALGIAAAVLLSRRNKLRQMRTGERQSILWPVLGLIFGLPLIVFVVTGL
PVSFEAPQATRFNLVGGWQIRPEFLSLFLALSFYTAAFIAEIIRAGILAVSRGQTEAASALGLTRRQSLRLVVVPQAFRV
VIPPLTSQYLNLTKNSSLGLAVGYPELVAVGSTVLNQTGQSVEVVAIWMVVYLGLSVATAAFMNWFNARVALVER

Specific function: Part of a binding-protein-dependent transport system for L-amino acids, affects the uptake as well as efflux of these amino acids. Probably responsible for the translocation of the substrate across the membrane [H]

COG id: COG4597

COG function: function code E; ABC-type amino acid transport system, permease component

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein (Probable) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 ABC transmembrane type-1 domain [H]

Homologues:

Organism=Escherichia coli, GI48994930, Length=379, Percent_Identity=48.5488126649077, Blast_Score=326, Evalue=1e-90,
Organism=Escherichia coli, GI1786873, Length=127, Percent_Identity=36.2204724409449, Blast_Score=87, Evalue=1e-18,
Organism=Escherichia coli, GI1786874, Length=100, Percent_Identity=41, Blast_Score=86, Evalue=4e-18,
Organism=Escherichia coli, GI1788226, Length=133, Percent_Identity=32.3308270676692, Blast_Score=80, Evalue=2e-16,
Organism=Escherichia coli, GI1787030, Length=151, Percent_Identity=30.4635761589404, Blast_Score=70, Evalue=3e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR010065
- InterPro:   IPR000515 [H]

Pfam domain/function: PF00528 BPD_transp_1 [H]

EC number: NA

Molecular weight: Translated: 42946; Mature: 42815

Theoretical pI: Translated: 11.51; Mature: 11.51

Prosite motif: PS50928 ABC_TM1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
1.5 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.3 %Met     (Mature Protein)
1.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTIDTSSISLSHERIGLMRNPRTRGLIIQTVLIIAILAFAAWLINNTVNNLTRANIASGF
CCCCCCCCCCCHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCH
DFLSARAGFDIGQVPIAYSANSSYGRALLVGITNTVIVAGAGIVLATIVGFVIGIGRLSR
HHHHHHCCCCCCCCCEEEECCCCCCCEEEEEEHHHHHHHCHHHHHHHHHHHHHHHHHHHH
NYLVRGLSTIYVETFRNVPPLLVILFWYFGVLSVLPLPREALELPFGAYLSNRGLQMPAA
HHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHCCCCHHHHHCCHHHHHCCCCCCCCHH
RFEPLAVWTLAAFALGIAAAVLLSRRNKLRQMRTGERQSILWPVLGLIFGLPLIVFVVTG
HCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHC
LPVSFEAPQATRFNLVGGWQIRPEFLSLFLALSFYTAAFIAEIIRAGILAVSRGQTEAAS
CCCEECCCCCCEEEEEECCEECHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHH
ALGLTRRQSLRLVVVPQAFRVVIPPLTSQYLNLTKNSSLGLAVGYPELVAVGSTVLNQTG
HHHHHHHCCEEEEEECCCCEEEECCHHHHHHCCCCCCCCEEEECCHHHHHHHHHHHHCCC
QSVEVVAIWMVVYLGLSVATAAFMNWFNARVALVER
CCHHHHHHHHHHHHHHHHHHHHHHHHHCCEEEEECC
>Mature Secondary Structure 
TIDTSSISLSHERIGLMRNPRTRGLIIQTVLIIAILAFAAWLINNTVNNLTRANIASGF
CCCCCCCCCCHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCH
DFLSARAGFDIGQVPIAYSANSSYGRALLVGITNTVIVAGAGIVLATIVGFVIGIGRLSR
HHHHHHCCCCCCCCCEEEECCCCCCCEEEEEEHHHHHHHCHHHHHHHHHHHHHHHHHHHH
NYLVRGLSTIYVETFRNVPPLLVILFWYFGVLSVLPLPREALELPFGAYLSNRGLQMPAA
HHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHCCCCHHHHHCCHHHHHCCCCCCCCHH
RFEPLAVWTLAAFALGIAAAVLLSRRNKLRQMRTGERQSILWPVLGLIFGLPLIVFVVTG
HCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHC
LPVSFEAPQATRFNLVGGWQIRPEFLSLFLALSFYTAAFIAEIIRAGILAVSRGQTEAAS
CCCEECCCCCCEEEEEECCEECHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHH
ALGLTRRQSLRLVVVPQAFRVVIPPLTSQYLNLTKNSSLGLAVGYPELVAVGSTVLNQTG
HHHHHHHCCEEEEEECCCCEEEECCHHHHHHCCCCCCCCEEEECCHHHHHHHHHHHHCCC
QSVEVVAIWMVVYLGLSVATAAFMNWFNARVALVER
CCHHHHHHHHHHHHHHHHHHHHHHHHHCCEEEEECC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 8898392 [H]