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The map label for this gene is comE [H]

Identifier: 110633423

GI number: 110633423

Start: 1173459

End: 1174058

Strand: Direct

Name: comE [H]

Synonym: Meso_1069

Alternate gene names: 110633423

Gene position: 1173459-1174058 (Clockwise)

Preceding gene: 110633422

Following gene: 110633426

Centisome position: 26.59

GC content: 64.5

Gene sequence:

>600_bases
ATGCCGGAAAGCAACGAACGCAAGGTGATGAGCCGGGCCGACCTGACGAAGCGACTGGTCAGCAAACTCAGGAACGAGGA
AGCCGTCGTCGGCGGTATCGGCTGGACGAATTTCGAGCTCTGGGGCGCCGGCCAGCGGCCGCAGAATTTTTATATGCTTG
GCTCCATGGGCCTTGCATTTCCCATCGCGCTCGGGGTCGCGATCGCGCAGCCGAAACGCCGCGTCATCGGGCTCGAGGGC
GACGGCTCGCTTCTCATGCAAGTGGGCGCGCTTGGGACCATCGCCAGCCGCAACCAGAGGAACCTCGTCATGATCGTCTG
GGACAACGGCGCCTATCAGATCACCGGCGGGCAGCCTGCCGCCACCGCCACGGTTGTCGATGTGGTGGGGCTCGCCCGCG
CCTCCGGCCTTGAAAAATCGTTTTGGGCGAAGGACGAGGCCCACTTCGAACAGCTGGTCGACCGCGCGCTTTCGGAGGAG
GGGCCCTTCTTCATCGCCGTCAAGATCGATAGTGCCAAGCCGGCGGCCACCACGCACCGCGATCCCGTGCAGATCCGCGA
GCGTTTCATGCGCGGGCTGGGCGTGAGGGAAGCGATTTAG

Upstream 100 bases:

>100_bases
GGACCGTCAGCCAAGCCGTCTCCACCCAGGCTCCGGCCGCCATCATCCTGAACGCGCTGCTCACCGGCGGCAAGGTCGAG
AAGAAGAGGGAGGTCTGATC

Downstream 100 bases:

>100_bases
CGGGGTTCCCACCCTTCCCACAAGGGGGAGGGTGGGCGCCTTTTCCTCAAATCTTCGTATGCTTCCAATAGAGCAGGCGC
CAGCTTTCCGCGCTTCTGCT

Product: hypothetical protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 199; Mature: 198

Protein sequence:

>199_residues
MPESNERKVMSRADLTKRLVSKLRNEEAVVGGIGWTNFELWGAGQRPQNFYMLGSMGLAFPIALGVAIAQPKRRVIGLEG
DGSLLMQVGALGTIASRNQRNLVMIVWDNGAYQITGGQPAATATVVDVVGLARASGLEKSFWAKDEAHFEQLVDRALSEE
GPFFIAVKIDSAKPAATTHRDPVQIRERFMRGLGVREAI

Sequences:

>Translated_199_residues
MPESNERKVMSRADLTKRLVSKLRNEEAVVGGIGWTNFELWGAGQRPQNFYMLGSMGLAFPIALGVAIAQPKRRVIGLEG
DGSLLMQVGALGTIASRNQRNLVMIVWDNGAYQITGGQPAATATVVDVVGLARASGLEKSFWAKDEAHFEQLVDRALSEE
GPFFIAVKIDSAKPAATTHRDPVQIRERFMRGLGVREAI
>Mature_198_residues
PESNERKVMSRADLTKRLVSKLRNEEAVVGGIGWTNFELWGAGQRPQNFYMLGSMGLAFPIALGVAIAQPKRRVIGLEGD
GSLLMQVGALGTIASRNQRNLVMIVWDNGAYQITGGQPAATATVVDVVGLARASGLEKSFWAKDEAHFEQLVDRALSEEG
PFFIAVKIDSAKPAATTHRDPVQIRERFMRGLGVREAI

Specific function: Catalyzes the decarboxylation of sulfopyruvic acid to sulfoacetaldehyde [H]

COG id: COG0028

COG function: function code EH; Thiamine pyrophosphate-requiring enzymes [acetolactate synthase, pyruvate dehydrogenase (cytochrome), glyoxylate carboligase, phosphonopyruvate decarboxylase]

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the TPP enzyme family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR022494
- InterPro:   IPR011766 [H]

Pfam domain/function: PF02775 TPP_enzyme_C [H]

EC number: =4.1.1.79 [H]

Molecular weight: Translated: 21678; Mature: 21547

Theoretical pI: Translated: 10.00; Mature: 10.00

Prosite motif: PS00187 TPP_ENZYMES

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
3.5 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
3.0 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPESNERKVMSRADLTKRLVSKLRNEEAVVGGIGWTNFELWGAGQRPQNFYMLGSMGLAF
CCCCCHHHHHHHHHHHHHHHHHHCCCCEEEECCCCCCEEEEECCCCCCCEEEECCCCHHH
PIALGVAIAQPKRRVIGLEGDGSLLMQVGALGTIASRNQRNLVMIVWDNGAYQITGGQPA
HHHHHHHHCCCCCEEEEECCCCCEEEECCCHHHHCCCCCCCEEEEEECCCEEEEECCCCC
ATATVVDVVGLARASGLEKSFWAKDEAHFEQLVDRALSEEGPFFIAVKIDSAKPAATTHR
HHHHHHHHHHHHHHCCCCHHHCCCCHHHHHHHHHHHHCCCCCEEEEEEECCCCCCCCCCC
DPVQIRERFMRGLGVREAI
CHHHHHHHHHHCCCCCCCC
>Mature Secondary Structure 
PESNERKVMSRADLTKRLVSKLRNEEAVVGGIGWTNFELWGAGQRPQNFYMLGSMGLAF
CCCCHHHHHHHHHHHHHHHHHHCCCCEEEECCCCCCEEEEECCCCCCCEEEECCCCHHH
PIALGVAIAQPKRRVIGLEGDGSLLMQVGALGTIASRNQRNLVMIVWDNGAYQITGGQPA
HHHHHHHHCCCCCEEEEECCCCCEEEECCCHHHHCCCCCCCEEEEEECCCEEEEECCCCC
ATATVVDVVGLARASGLEKSFWAKDEAHFEQLVDRALSEEGPFFIAVKIDSAKPAATTHR
HHHHHHHHHHHHHHCCCCHHHCCCCHHHHHHHHHHHHCCCCCEEEEEEECCCCCCCCCCC
DPVQIRERFMRGLGVREAI
CHHHHHHHHHHCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8688087; 10940029 [H]