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The map label for this gene is citE [H]

Identifier: 110633366

GI number: 110633366

Start: 1109476

End: 1110351

Strand: Reverse

Name: citE [H]

Synonym: Meso_1012

Alternate gene names: 110633366

Gene position: 1110351-1109476 (Counterclockwise)

Preceding gene: 110633367

Following gene: 110633364

Centisome position: 25.16

GC content: 62.21

Gene sequence:

>876_bases
ATGCGCTCGCTGCTTTTCGTTCCCGCTGATTCGGAGCGCAAAATGACGAAAGCGCTTCAATCCGGGGCCGACGTGCTGAT
CCTGGACCTTGAGGATTCGGTTGGCCCTTCCCGAAAAGAAGAAGCGCGCCGGCTTGCGGCCGACTTTCTCGCGCGGCACG
AGACGCCAACCCTAATATATGTGCGCGTGAACGCGCTCTCGACGGGACTGACCGATGAGGATCTGGCGGCGGTCATGCCG
GGCCGACCGGCAGGGATCATGCTGCCCAAAGCCGAAGGGGGGCAGGACATCTCCCTCCTTTCCGTTAAGCTCCGCGTTTG
TGAGGCCGAGAACGGGATTGAGGATGGCGCAACGCACATCCTTCCCATTATCACGGAAACCGGAAAGGCCATATTTTCGG
CCCAGACGATCGCTGGCTCAAGCGAGCGGCTTTCCGCTCTCACCTGGGGAGCGGAGGACCTTTCCGCCGCAATCGGAGCG
CGGGCTACCCGCGATGATGCAGGCCGATATACGAGTGTTTTCGCGCTTGCACGCTCCATCACCCTCTTTGCCGCCGCCGA
TGCCGGCGTGCCGGCGATCGACACTGTCTTCCCCGCCTTCCGGGATCTCGATGCCTTCGCACGCGATTGCAGAGAGGCGG
AACGCGACGGCTTTACGGGAAAGATGGCCATCCATCCCTCGCAGGTGCCGTTCATCAATGCCGCCTTCACCCCTTCCGAG
GAGGCGATCGATCATTCGCGCCGGGTTGTTGCGGCCTTCGCCGAAACCGGGGAAACCGGCGTTGTGAATCTCGATGGTGA
AATGGTCGATCGGCCCCATTTCATCCGGGCAACGCGCATCCTGGAACGCGCGCGCCTTGCCGGACTGGGGGAATAG

Upstream 100 bases:

>100_bases
ACCGCGGCATCGTCGAATTCGAGCATCGCGGCTTCAATCAACACGATGTGCTGGTGGCCCGGTGCCTGCGGCAAGCGATG
ATCGTGAAAAGGAACGCCTG

Downstream 100 bases:

>100_bases
GGCAATACGGCAGCAGGCAGTAAGTGGGGTCACAACGGTCGCCAGCAGCTGCGAAAAATTTTCCGCTACTGCCTTACTGC
GCTATTCCCTTACTACCTTA

Product: HpcH/HpaI aldolase

Products: NA

Alternate protein names: Citrase beta chain; Citrate (pro-3S)-lyase subunit beta; Citryl-CoA lyase subunit [H]

Number of amino acids: Translated: 291; Mature: 291

Protein sequence:

>291_residues
MRSLLFVPADSERKMTKALQSGADVLILDLEDSVGPSRKEEARRLAADFLARHETPTLIYVRVNALSTGLTDEDLAAVMP
GRPAGIMLPKAEGGQDISLLSVKLRVCEAENGIEDGATHILPIITETGKAIFSAQTIAGSSERLSALTWGAEDLSAAIGA
RATRDDAGRYTSVFALARSITLFAAADAGVPAIDTVFPAFRDLDAFARDCREAERDGFTGKMAIHPSQVPFINAAFTPSE
EAIDHSRRVVAAFAETGETGVVNLDGEMVDRPHFIRATRILERARLAGLGE

Sequences:

>Translated_291_residues
MRSLLFVPADSERKMTKALQSGADVLILDLEDSVGPSRKEEARRLAADFLARHETPTLIYVRVNALSTGLTDEDLAAVMP
GRPAGIMLPKAEGGQDISLLSVKLRVCEAENGIEDGATHILPIITETGKAIFSAQTIAGSSERLSALTWGAEDLSAAIGA
RATRDDAGRYTSVFALARSITLFAAADAGVPAIDTVFPAFRDLDAFARDCREAERDGFTGKMAIHPSQVPFINAAFTPSE
EAIDHSRRVVAAFAETGETGVVNLDGEMVDRPHFIRATRILERARLAGLGE
>Mature_291_residues
MRSLLFVPADSERKMTKALQSGADVLILDLEDSVGPSRKEEARRLAADFLARHETPTLIYVRVNALSTGLTDEDLAAVMP
GRPAGIMLPKAEGGQDISLLSVKLRVCEAENGIEDGATHILPIITETGKAIFSAQTIAGSSERLSALTWGAEDLSAAIGA
RATRDDAGRYTSVFALARSITLFAAADAGVPAIDTVFPAFRDLDAFARDCREAERDGFTGKMAIHPSQVPFINAAFTPSE
EAIDHSRRVVAAFAETGETGVVNLDGEMVDRPHFIRATRILERARLAGLGE

Specific function: Represents a citryl-ACP lyase [H]

COG id: COG2301

COG function: function code G; Citrate lyase beta subunit

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the HpcH/HpaI aldolase family. Citrate lyase beta subunit subfamily [H]

Homologues:

Organism=Homo sapiens, GI45545437, Length=289, Percent_Identity=31.4878892733564, Blast_Score=136, Evalue=2e-32,
Organism=Escherichia coli, GI87081764, Length=295, Percent_Identity=34.9152542372881, Blast_Score=126, Evalue=2e-30,
Organism=Caenorhabditis elegans, GI17557458, Length=298, Percent_Identity=31.5436241610738, Blast_Score=123, Evalue=1e-28,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005000
- InterPro:   IPR011206
- InterPro:   IPR006475
- InterPro:   IPR015813 [H]

Pfam domain/function: PF03328 HpcH_HpaI [H]

EC number: =4.1.3.6; =4.1.3.34 [H]

Molecular weight: Translated: 31134; Mature: 31134

Theoretical pI: Translated: 4.80; Mature: 4.80

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRSLLFVPADSERKMTKALQSGADVLILDLEDSVGPSRKEEARRLAADFLARHETPTLIY
CCCEEEEECCCHHHHHHHHHCCCCEEEEECCCCCCCCHHHHHHHHHHHHHHHCCCCEEEE
VRVNALSTGLTDEDLAAVMPGRPAGIMLPKAEGGQDISLLSVKLRVCEAENGIEDGATHI
EEEEEHCCCCCHHHHHHHCCCCCCEEEEECCCCCCCEEEEEEEEEEECCCCCCCCCCCEE
LPIITETGKAIFSAQTIAGSSERLSALTWGAEDLSAAIGARATRDDAGRYTSVFALARSI
EEEEECCCCHHEEHHHHCCCHHHHHHEECCHHHHHHHHCCCCCCCCCCHHHHHHHHHHHH
TLFAAADAGVPAIDTVFPAFRDLDAFARDCREAERDGFTGKMAIHPSQVPFINAAFTPSE
HEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEECCCCCCEEEEECCCCH
EAIDHSRRVVAAFAETGETGVVNLDGEMVDRPHFIRATRILERARLAGLGE
HHHHHHHHEEEEHHCCCCCEEEECCCHHCCCCHHHHHHHHHHHHHHCCCCC
>Mature Secondary Structure
MRSLLFVPADSERKMTKALQSGADVLILDLEDSVGPSRKEEARRLAADFLARHETPTLIY
CCCEEEEECCCHHHHHHHHHCCCCEEEEECCCCCCCCHHHHHHHHHHHHHHHCCCCEEEE
VRVNALSTGLTDEDLAAVMPGRPAGIMLPKAEGGQDISLLSVKLRVCEAENGIEDGATHI
EEEEEHCCCCCHHHHHHHCCCCCCEEEEECCCCCCCEEEEEEEEEEECCCCCCCCCCCEE
LPIITETGKAIFSAQTIAGSSERLSALTWGAEDLSAAIGARATRDDAGRYTSVFALARSI
EEEEECCCCHHEEHHHHCCCHHHHHHEECCHHHHHHHHCCCCCCCCCCHHHHHHHHHHHH
TLFAAADAGVPAIDTVFPAFRDLDAFARDCREAERDGFTGKMAIHPSQVPFINAAFTPSE
HEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEECCCCCCEEEEECCCCH
EAIDHSRRVVAAFAETGETGVVNLDGEMVDRPHFIRATRILERARLAGLGE
HHHHHHHHEEEEHHCCCCCEEEECCCHHCCCCHHHHHHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9457870 [H]