Click here to switch to the map view.

The map label for this gene is acpS

Identifier: 110633302

GI number: 110633302

Start: 1045954

End: 1046355

Strand: Direct

Name: acpS

Synonym: Meso_0948

Alternate gene names: 110633302

Gene position: 1045954-1046355 (Clockwise)

Preceding gene: 110633301

Following gene: 110633303

Centisome position: 23.7

GC content: 58.46

Gene sequence:

>402_bases
ATGATCGTCGGAATCGGCAGTGACCTCATCGATATCCGCCGTGTCGAGAAAGCGCTTGAGCGGCATGGCGAGCGCTTCAC
TCATCGCGTTTTCACAGAGGTCGAGCGCGTCAAATCCGATCGGAGGCGCATGCGCGCCGCTTCTTATGCGAAGCGTTTTG
CAGCCAAGGAGGCTTGCGCCAAGGCGCTAGGGACGGGACTGGCTCAAGGCGTATTCTGGCGCGATATGGGCGTGGTGAAT
TTGCCGGGCGGCAAGCCTACCATGCATTTGACGGGCGGGGCGGCCGAGCGGCTGAATGCATTGATTCCGGCAGGTCACCG
GCCGCTTATCCATCTCACCATTACAGATGATTTTCCTCTTGCCCAGGCATTCGTCATTATCGAGGCAGTGTCCGTAGAAT
AG

Upstream 100 bases:

>100_bases
TGACTCGCGGAGCGACGAATGCCTTTCGCGAGGAACGGCGAAAGCGGCTGGCGGAAAGGGCGCGGCGCCGGGCCGCGGGC
GGCGCGGACGCGGTGGCATC

Downstream 100 bases:

>100_bases
CCTTGGATCCATGGTGAACAAAGAAGCTGCGAATGCCGCAGGTCGGTGCATTGCCGTAAAGGCCGCAAGCCGATAAGACG
AATTGCAAAATGGGTCGCCT

Product: holo-acyl-carrier-protein synthase

Products: NA

Alternate protein names: Holo-ACP synthase; 4'-phosphopantetheinyl transferase AcpS

Number of amino acids: Translated: 133; Mature: 133

Protein sequence:

>133_residues
MIVGIGSDLIDIRRVEKALERHGERFTHRVFTEVERVKSDRRRMRAASYAKRFAAKEACAKALGTGLAQGVFWRDMGVVN
LPGGKPTMHLTGGAAERLNALIPAGHRPLIHLTITDDFPLAQAFVIIEAVSVE

Sequences:

>Translated_133_residues
MIVGIGSDLIDIRRVEKALERHGERFTHRVFTEVERVKSDRRRMRAASYAKRFAAKEACAKALGTGLAQGVFWRDMGVVN
LPGGKPTMHLTGGAAERLNALIPAGHRPLIHLTITDDFPLAQAFVIIEAVSVE
>Mature_133_residues
MIVGIGSDLIDIRRVEKALERHGERFTHRVFTEVERVKSDRRRMRAASYAKRFAAKEACAKALGTGLAQGVFWRDMGVVN
LPGGKPTMHLTGGAAERLNALIPAGHRPLIHLTITDDFPLAQAFVIIEAVSVE

Specific function: Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein

COG id: COG0736

COG function: function code I; Phosphopantetheinyl transferase (holo-ACP synthase)

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the P-Pant transferase superfamily. AcpS family

Homologues:

Organism=Escherichia coli, GI1788916, Length=128, Percent_Identity=36.71875, Blast_Score=74, Evalue=4e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): ACPS_MESSB (Q11JT0)

Other databases:

- EMBL:   CP000390
- RefSeq:   YP_673510.1
- ProteinModelPortal:   Q11JT0
- SMR:   Q11JT0
- STRING:   Q11JT0
- GeneID:   4180325
- GenomeReviews:   CP000390_GR
- KEGG:   mes:Meso_0948
- NMPDR:   fig|266779.1.peg.3918
- eggNOG:   COG0736
- HOGENOM:   HBG734479
- OMA:   QGVFWRD
- PhylomeDB:   Q11JT0
- BioCyc:   MSP266779:MESO_0948-MONOMER
- GO:   GO:0005737
- HAMAP:   MF_00101
- InterPro:   IPR008278
- InterPro:   IPR002582
- InterPro:   IPR004568
- ProDom:   PD004282
- TIGRFAMs:   TIGR00516
- TIGRFAMs:   TIGR00556

Pfam domain/function: PF01648 ACPS; SSF56214 4-PPT_transf

EC number: =2.7.8.7

Molecular weight: Translated: 14645; Mature: 14645

Theoretical pI: Translated: 10.54; Mature: 10.54

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
3.0 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIVGIGSDLIDIRRVEKALERHGERFTHRVFTEVERVKSDRRRMRAASYAKRFAAKEACA
CEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
KALGTGLAQGVFWRDMGVVNLPGGKPTMHLTGGAAERLNALIPAGHRPLIHLTITDDFPL
HHHHHHHHHHHHHHCCCEEECCCCCCEEEECCCHHHHHHHHCCCCCCCEEEEEECCCCCH
AQAFVIIEAVSVE
HHHHHHHHHHCCC
>Mature Secondary Structure
MIVGIGSDLIDIRRVEKALERHGERFTHRVFTEVERVKSDRRRMRAASYAKRFAAKEACA
CEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
KALGTGLAQGVFWRDMGVVNLPGGKPTMHLTGGAAERLNALIPAGHRPLIHLTITDDFPL
HHHHHHHHHHHHHHCCCEEECCCCCCEEEECCCHHHHHHHHCCCCCCCEEEEEECCCCCH
AQAFVIIEAVSVE
HHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA