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The map label for this gene is cycK [H]

Identifier: 110633253

GI number: 110633253

Start: 988714

End: 990702

Strand: Direct

Name: cycK [H]

Synonym: Meso_0899

Alternate gene names: 110633253

Gene position: 988714-990702 (Clockwise)

Preceding gene: 110633252

Following gene: 110633254

Centisome position: 22.41

GC content: 62.8

Gene sequence:

>1989_bases
ATGAGCGTCGAACTTGGCCATTTCGCACTCGTGCTGGCGCTGGCGCTGGCCTTGGTGCAGGCGCTGGTGCCGCTCCTCGG
CGCGCGCTTGGGCAGCGCTCCGCTGATGCGGATGGGCGAACCGGTGGCCATTACCGGGTTTGCGCTGATCGCGTTCGCCT
TCGCGGCGCTGGTGCTTGCCTATGTCCAATCGGATTTCTCGGTGCTGAATGTGTGGGAGAACTCACACTCGGCCAAGCCG
CTTCTGTTCAAGATTACCGGGACTTGGGGCAATCATGAAGGCTCGATGCTCCTTTGGGTGCTGATCCTAGCCTTTTTCGG
GGCTCTTGTGGCAGCCTTCGGCCAGAATCTGCCGCCAACGCTCAGGGCCAATGTGCTGGCCATACAGGGCCTGATTGCCA
GCGCCTTCCTCCTGTTCATCCTCTTTACCTCCAATCCCTTCATCCGCCTTGAGCGGGCGCCGATTGAAGGCCGTGACCTC
AATCCGATCCTGCAGGACATCGGGCTCGCGATCCATCCGCCGCTGCTCTATCTCGGCTATGTGGGGTTCTCGATCTCCTT
TTCGTTCGCGGTGGCGGCGCTGATCGACGGGCGCCTGGACGCGGCTTGGGCACGGTGGGTGCGTCCGTGGACGCTCGTTG
CCTGGGCCTTCCTCACCGGCGGCATCGCGATGGGCTCCTACTGGGCCTATTATGAATTGGGATGGGGCGGCTTCTGGTTC
TGGGACCCGGTGGAGAACGCTTCCCTGATGCCCTGGCTGGCGGGTACGGCGTTGCTGCACTCGGCCATTGTCATGGAAAA
GCGCTCGGCACTGAAAATCTGGACGGTGCTGCTGGCCATTCTCACTTTTTCGCTGTCGCTGCTTGGCACATTTCTGGTCC
GCTCGGGCGTTTTGACCTCTGTTCACTCCTTTGCGACAGATCCCACACGCGGCGTCTTCATTCTTGCGATACTGGTGTTC
TTTATCGGCGGCGCTCTGGCTTTGTTTGCAGTAAGGGGCGCGTCGCTCGCGCCGGGTGGACTGTTCCATCCCATTTCCAG
GGAGGGGGCGCTTGTCTTCAACAATCTGATGCTTACGACCGCGGCGGCGACGGTGCTCATCGGCACTCTCTACCCCCTGC
TGATCGAGGCCATCAGCGAAGACAAGATTTCCGTCGGCGCGCCGTTCTTTAATCTGACCTTCGTGCCGCTGTTCCTGCCG
CTCCTGCTGGCCGTGCCTTTTGGGCCGCTTCTCGCCTGGAAGCGCGGCGATCTGCCAGGAGCTCTCCAGCGCCTGCAATT
CGCGTTCTGGGCAGCCGGGGCGGCCGCAATCGCGAGCTATTTCCTGATTGACCGCGCCAACGCCGCAGCTGCGCTCGGCA
TCGGCCTGGGGCTGTGGCTTGTCTTCGGCGCGCTGACAGATCTCGCTTTCAAATCCGGCATCGGCAAGGTCGGGCCAGCA
CTTGCCCTTCGCCGGCTCTCCGGCTTGCCCCTTTCGATGTTCGGCACCTGTTTCGCACATGCCGGGCTGGGCCTTACCGT
GCTCGGCATTGTCTCCGTCACCGCGCTTCAGGCCGAGAAAATCCTGACAATGCAGCCAGGCCAGAGCACCGAAATCAGCG
GCTACACTCTTCGCTTCGTGGATCTGCGGCCCTTCACCGGCCCAAATTACACGGAAGACCGCGCCGAGTTCGCGCTCGGG
ACCACCCGCGGTGCGTCGCTGGGGGAACTCGTTTCGTCCAAGCGTCTTTATACGGCCCGGGGTATGCCGACGACCGAAGC
CGGCATCAGAACGATGGGCCTGAGCCAGCTCTATGTTTCGATCGGTGACCGTACACCGGCTGGGCTCGTCGTGCGGATCT
GGTGGAAGCCTTTCGTCACGCTGATCTGGGCCGGTGCGCTGGTGATGATGGGCGGCGGCTTCATCTCTCTCATGGACCGC
AGGCTGCGCGTCGGTGCGCCGGCAAGGCGCAAAGCAGCGCTCGCGGCGGACGGTGGGGGAACGCGATGA

Upstream 100 bases:

>100_bases
GATACCGTCCTTGCGAAGCACGACGAGACCTATATGCCCCGTGAAGTGGCGGACAGGCTGAAAAAGGACGGCCTTTGGCA
GGAACAATGAGAAAGGTCCG

Downstream 100 bases:

>100_bases
TCTTTCGCGCATTTCTGCTTGTGCTCTGCCTGTTGGGATTTTCGGGCATCGCTGTTGCGGTGCAGCCTGATGAGATACTT
GTGGACCCTGCGCTCGAAGC

Product: cytochrome c-type biogenesis protein CcmF

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 662; Mature: 661

Protein sequence:

>662_residues
MSVELGHFALVLALALALVQALVPLLGARLGSAPLMRMGEPVAITGFALIAFAFAALVLAYVQSDFSVLNVWENSHSAKP
LLFKITGTWGNHEGSMLLWVLILAFFGALVAAFGQNLPPTLRANVLAIQGLIASAFLLFILFTSNPFIRLERAPIEGRDL
NPILQDIGLAIHPPLLYLGYVGFSISFSFAVAALIDGRLDAAWARWVRPWTLVAWAFLTGGIAMGSYWAYYELGWGGFWF
WDPVENASLMPWLAGTALLHSAIVMEKRSALKIWTVLLAILTFSLSLLGTFLVRSGVLTSVHSFATDPTRGVFILAILVF
FIGGALALFAVRGASLAPGGLFHPISREGALVFNNLMLTTAAATVLIGTLYPLLIEAISEDKISVGAPFFNLTFVPLFLP
LLLAVPFGPLLAWKRGDLPGALQRLQFAFWAAGAAAIASYFLIDRANAAAALGIGLGLWLVFGALTDLAFKSGIGKVGPA
LALRRLSGLPLSMFGTCFAHAGLGLTVLGIVSVTALQAEKILTMQPGQSTEISGYTLRFVDLRPFTGPNYTEDRAEFALG
TTRGASLGELVSSKRLYTARGMPTTEAGIRTMGLSQLYVSIGDRTPAGLVVRIWWKPFVTLIWAGALVMMGGGFISLMDR
RLRVGAPARRKAALAADGGGTR

Sequences:

>Translated_662_residues
MSVELGHFALVLALALALVQALVPLLGARLGSAPLMRMGEPVAITGFALIAFAFAALVLAYVQSDFSVLNVWENSHSAKP
LLFKITGTWGNHEGSMLLWVLILAFFGALVAAFGQNLPPTLRANVLAIQGLIASAFLLFILFTSNPFIRLERAPIEGRDL
NPILQDIGLAIHPPLLYLGYVGFSISFSFAVAALIDGRLDAAWARWVRPWTLVAWAFLTGGIAMGSYWAYYELGWGGFWF
WDPVENASLMPWLAGTALLHSAIVMEKRSALKIWTVLLAILTFSLSLLGTFLVRSGVLTSVHSFATDPTRGVFILAILVF
FIGGALALFAVRGASLAPGGLFHPISREGALVFNNLMLTTAAATVLIGTLYPLLIEAISEDKISVGAPFFNLTFVPLFLP
LLLAVPFGPLLAWKRGDLPGALQRLQFAFWAAGAAAIASYFLIDRANAAAALGIGLGLWLVFGALTDLAFKSGIGKVGPA
LALRRLSGLPLSMFGTCFAHAGLGLTVLGIVSVTALQAEKILTMQPGQSTEISGYTLRFVDLRPFTGPNYTEDRAEFALG
TTRGASLGELVSSKRLYTARGMPTTEAGIRTMGLSQLYVSIGDRTPAGLVVRIWWKPFVTLIWAGALVMMGGGFISLMDR
RLRVGAPARRKAALAADGGGTR
>Mature_661_residues
SVELGHFALVLALALALVQALVPLLGARLGSAPLMRMGEPVAITGFALIAFAFAALVLAYVQSDFSVLNVWENSHSAKPL
LFKITGTWGNHEGSMLLWVLILAFFGALVAAFGQNLPPTLRANVLAIQGLIASAFLLFILFTSNPFIRLERAPIEGRDLN
PILQDIGLAIHPPLLYLGYVGFSISFSFAVAALIDGRLDAAWARWVRPWTLVAWAFLTGGIAMGSYWAYYELGWGGFWFW
DPVENASLMPWLAGTALLHSAIVMEKRSALKIWTVLLAILTFSLSLLGTFLVRSGVLTSVHSFATDPTRGVFILAILVFF
IGGALALFAVRGASLAPGGLFHPISREGALVFNNLMLTTAAATVLIGTLYPLLIEAISEDKISVGAPFFNLTFVPLFLPL
LLAVPFGPLLAWKRGDLPGALQRLQFAFWAAGAAAIASYFLIDRANAAAALGIGLGLWLVFGALTDLAFKSGIGKVGPAL
ALRRLSGLPLSMFGTCFAHAGLGLTVLGIVSVTALQAEKILTMQPGQSTEISGYTLRFVDLRPFTGPNYTEDRAEFALGT
TRGASLGELVSSKRLYTARGMPTTEAGIRTMGLSQLYVSIGDRTPAGLVVRIWWKPFVTLIWAGALVMMGGGFISLMDRR
LRVGAPARRKAALAADGGGTR

Specific function: Required for the biogenesis of c-type cytochromes. Possible subunit of a heme lyase [H]

COG id: COG1138

COG function: function code O; Cytochrome c biogenesis factor

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ccmF/cycK/ccl1/nrfE/ccsA family [H]

Homologues:

Organism=Escherichia coli, GI1788524, Length=657, Percent_Identity=45.662100456621, Blast_Score=494, Evalue=1e-140,
Organism=Escherichia coli, GI1790511, Length=377, Percent_Identity=44.0318302387268, Blast_Score=261, Evalue=1e-70,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002541
- InterPro:   IPR003567
- InterPro:   IPR003568 [H]

Pfam domain/function: PF01578 Cytochrom_C_asm [H]

EC number: NA

Molecular weight: Translated: 70769; Mature: 70638

Theoretical pI: Translated: 10.27; Mature: 10.27

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
2.4 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
2.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSVELGHFALVLALALALVQALVPLLGARLGSAPLMRMGEPVAITGFALIAFAFAALVLA
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHCCCCCCHHHHHHHHHHHHHHHHH
YVQSDFSVLNVWENSHSAKPLLFKITGTWGNHEGSMLLWVLILAFFGALVAAFGQNLPPT
HHHCCCCEEEEECCCCCCCCEEEEEEECCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCH
LRANVLAIQGLIASAFLLFILFTSNPFIRLERAPIEGRDLNPILQDIGLAIHPPLLYLGY
HHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEECCCCCCCCCHHHHHCCCCCCCHHHHHHH
VGFSISFSFAVAALIDGRLDAAWARWVRPWTLVAWAFLTGGIAMGSYWAYYELGWGGFWF
HHHHHHHHHHHHHHHCCCHHHHHHHHHCHHHHHHHHHHHCCHHHCCEEEEEEECCCCEEE
WDPVENASLMPWLAGTALLHSAIVMEKRSALKIWTVLLAILTFSLSLLGTFLVRSGVLTS
ECCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
VHSFATDPTRGVFILAILVFFIGGALALFAVRGASLAPGGLFHPISREGALVFNNLMLTT
HHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCHHHHHHHHH
AAATVLIGTLYPLLIEAISEDKISVGAPFFNLTFVPLFLPLLLAVPFGPLLAWKRGDLPG
HHHHHHHHHHHHHHHHHHCCCCEECCCCHHHHHHHHHHHHHHHHCCCCHHHCCCCCCCHH
ALQRLQFAFWAAGAAAIASYFLIDRANAAAALGIGLGLWLVFGALTDLAFKSGIGKVGPA
HHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHH
LALRRLSGLPLSMFGTCFAHAGLGLTVLGIVSVTALQAEKILTMQPGQSTEISGYTLRFV
HHHHHHCCCCHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHEEEECCCCCCCCCCEEEEEE
DLRPFTGPNYTEDRAEFALGTTRGASLGELVSSKRLYTARGMPTTEAGIRTMGLSQLYVS
EECCCCCCCCCCCHHHHHCCCCCCCHHHHHHHCCCEEEECCCCCCHHHHHHHHHHHHHHC
IGDRTPAGLVVRIWWKPFVTLIWAGALVMMGGGFISLMDRRLRVGAPARRKAALAADGGG
CCCCCCCCEEEEEHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHCCCCHHHCEEEECCCCC
TR
CC
>Mature Secondary Structure 
SVELGHFALVLALALALVQALVPLLGARLGSAPLMRMGEPVAITGFALIAFAFAALVLA
CCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHCCCCCCHHHHHHHHHHHHHHHHH
YVQSDFSVLNVWENSHSAKPLLFKITGTWGNHEGSMLLWVLILAFFGALVAAFGQNLPPT
HHHCCCCEEEEECCCCCCCCEEEEEEECCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCH
LRANVLAIQGLIASAFLLFILFTSNPFIRLERAPIEGRDLNPILQDIGLAIHPPLLYLGY
HHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEECCCCCCCCCHHHHHCCCCCCCHHHHHHH
VGFSISFSFAVAALIDGRLDAAWARWVRPWTLVAWAFLTGGIAMGSYWAYYELGWGGFWF
HHHHHHHHHHHHHHHCCCHHHHHHHHHCHHHHHHHHHHHCCHHHCCEEEEEEECCCCEEE
WDPVENASLMPWLAGTALLHSAIVMEKRSALKIWTVLLAILTFSLSLLGTFLVRSGVLTS
ECCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
VHSFATDPTRGVFILAILVFFIGGALALFAVRGASLAPGGLFHPISREGALVFNNLMLTT
HHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCHHHHHHHHH
AAATVLIGTLYPLLIEAISEDKISVGAPFFNLTFVPLFLPLLLAVPFGPLLAWKRGDLPG
HHHHHHHHHHHHHHHHHHCCCCEECCCCHHHHHHHHHHHHHHHHCCCCHHHCCCCCCCHH
ALQRLQFAFWAAGAAAIASYFLIDRANAAAALGIGLGLWLVFGALTDLAFKSGIGKVGPA
HHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHH
LALRRLSGLPLSMFGTCFAHAGLGLTVLGIVSVTALQAEKILTMQPGQSTEISGYTLRFV
HHHHHHCCCCHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHEEEECCCCCCCCCCEEEEEE
DLRPFTGPNYTEDRAEFALGTTRGASLGELVSSKRLYTARGMPTTEAGIRTMGLSQLYVS
EECCCCCCCCCCCHHHHHCCCCCCCHHHHHHHCCCEEEECCCCCCHHHHHHHHHHHHHHC
IGDRTPAGLVVRIWWKPFVTLIWAGALVMMGGGFISLMDRRLRVGAPARRKAALAADGGG
CCCCCCCCEEEEEHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHCCCCHHHCEEEECCCCC
TR
CC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 7715602; 11481430 [H]