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The map label for this gene is qseB [H]

Identifier: 110633248

GI number: 110633248

Start: 984408

End: 985076

Strand: Direct

Name: qseB [H]

Synonym: Meso_0894

Alternate gene names: 110633248

Gene position: 984408-985076 (Clockwise)

Preceding gene: 110633247

Following gene: 110633249

Centisome position: 22.31

GC content: 60.99

Gene sequence:

>669_bases
ATGCGCATTCTGGTTGTCGAGGACGACAAAGACCTGAACCGGCAGATTAGCGTCGCGCTGGAAGATGCCGGTTACGTGGT
CGATCGCGCCTTTGACGGCGAAGAGGGCCATTTCCTAGGCGATACCGAACCATACGACGCGATCGTGCTCGATATCGGCC
TGCCGCAGATGGATGGGATCAGCGTGCTGGAACGTTGGCGGCGCGATGGGCGCAAGATGCCCGTTCTGATCCTGACCGCG
CGCGACCGCTGGAGCGATAAGGTGGCCGGCATCGATGCCGGCGCGGACGACTACGTGACCAAGCCCTTCCATATGGAGGA
GGTGCTGGCGCGCGTGCGGGCGCTCATCCGCCGCGCAGCGGGACATGCATCCTCCGAGCTTTACTGCGGACCTTTGCGGC
TGGACACCAAGGCGTCCAAGGCGGACATGGATGGCGTGCCGCTGAAGCTCACCTCCCACGAATACCGGATGCTTGCTTAC
CTGATGCATCACAAAGGTTCCGTGGTTTCGCGAACGGAGCTGGTGGAGCATCTTTACGATCAGGACTTCGACCGCGATTC
CAATACGATCGAGGTTTTCGTCGGGCGCCTGCGCAAGAAGCTGGGCGTGGACCTGATAGAAACTGTGCGAGGCATGGGAT
ACCGTATGCGCGAGCCGAATGACGGATGA

Upstream 100 bases:

>100_bases
CCTGGTGCCTGCCCGAGACGGCGAACGACCGCGGCGGGTGGAAGTTACCGTGCCGGTGCGATAATCAATTACATTTCTAA
GAATTGGGCGATCTGCACTC

Downstream 100 bases:

>100_bases
GGCAGATCACGCGGTAGCTCGCCCGGTGGCACGAATGCAGGCTTGGCTTACGAGCCTGCCGCGCCGGCTCACTTTCCGTG
TCGTGCTCTTTTCGTCCGTT

Product: two component transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 222; Mature: 222

Protein sequence:

>222_residues
MRILVVEDDKDLNRQISVALEDAGYVVDRAFDGEEGHFLGDTEPYDAIVLDIGLPQMDGISVLERWRRDGRKMPVLILTA
RDRWSDKVAGIDAGADDYVTKPFHMEEVLARVRALIRRAAGHASSELYCGPLRLDTKASKADMDGVPLKLTSHEYRMLAY
LMHHKGSVVSRTELVEHLYDQDFDRDSNTIEVFVGRLRKKLGVDLIETVRGMGYRMREPNDG

Sequences:

>Translated_222_residues
MRILVVEDDKDLNRQISVALEDAGYVVDRAFDGEEGHFLGDTEPYDAIVLDIGLPQMDGISVLERWRRDGRKMPVLILTA
RDRWSDKVAGIDAGADDYVTKPFHMEEVLARVRALIRRAAGHASSELYCGPLRLDTKASKADMDGVPLKLTSHEYRMLAY
LMHHKGSVVSRTELVEHLYDQDFDRDSNTIEVFVGRLRKKLGVDLIETVRGMGYRMREPNDG
>Mature_222_residues
MRILVVEDDKDLNRQISVALEDAGYVVDRAFDGEEGHFLGDTEPYDAIVLDIGLPQMDGISVLERWRRDGRKMPVLILTA
RDRWSDKVAGIDAGADDYVTKPFHMEEVLARVRALIRRAAGHASSELYCGPLRLDTKASKADMDGVPLKLTSHEYRMLAY
LMHHKGSVVSRTELVEHLYDQDFDRDSNTIEVFVGRLRKKLGVDLIETVRGMGYRMREPNDG

Specific function: Member of a two-component regulatory system qseB/qseC. Activates the flagella regulon by activating transcription of flhDC [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 response regulatory domain [H]

Homologues:

Organism=Escherichia coli, GI1787375, Length=218, Percent_Identity=43.5779816513761, Blast_Score=185, Evalue=2e-48,
Organism=Escherichia coli, GI1789402, Length=218, Percent_Identity=45.4128440366972, Blast_Score=180, Evalue=5e-47,
Organism=Escherichia coli, GI1786784, Length=225, Percent_Identity=40, Blast_Score=166, Evalue=9e-43,
Organism=Escherichia coli, GI1790552, Length=216, Percent_Identity=43.0555555555556, Blast_Score=164, Evalue=5e-42,
Organism=Escherichia coli, GI87082012, Length=219, Percent_Identity=39.7260273972603, Blast_Score=160, Evalue=6e-41,
Organism=Escherichia coli, GI1786599, Length=223, Percent_Identity=35.8744394618834, Blast_Score=125, Evalue=3e-30,
Organism=Escherichia coli, GI1789809, Length=225, Percent_Identity=32.8888888888889, Blast_Score=118, Evalue=3e-28,
Organism=Escherichia coli, GI1786911, Length=223, Percent_Identity=33.6322869955157, Blast_Score=114, Evalue=4e-27,
Organism=Escherichia coli, GI1790860, Length=222, Percent_Identity=32.8828828828829, Blast_Score=110, Evalue=5e-26,
Organism=Escherichia coli, GI1788394, Length=221, Percent_Identity=33.9366515837104, Blast_Score=110, Evalue=5e-26,
Organism=Escherichia coli, GI2367329, Length=228, Percent_Identity=35.0877192982456, Blast_Score=108, Evalue=3e-25,
Organism=Escherichia coli, GI1787229, Length=220, Percent_Identity=31.8181818181818, Blast_Score=107, Evalue=5e-25,
Organism=Escherichia coli, GI1790863, Length=228, Percent_Identity=31.140350877193, Blast_Score=101, Evalue=5e-23,
Organism=Escherichia coli, GI1788550, Length=108, Percent_Identity=35.1851851851852, Blast_Score=72, Evalue=2e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011006
- InterPro:   IPR001867
- InterPro:   IPR001789
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00072 Response_reg; PF00486 Trans_reg_C [H]

EC number: NA

Molecular weight: Translated: 25175; Mature: 25175

Theoretical pI: Translated: 5.40; Mature: 5.40

Prosite motif: PS50110 RESPONSE_REGULATORY ; PS00217 SUGAR_TRANSPORT_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
4.1 %Met     (Translated Protein)
4.5 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
4.1 %Met     (Mature Protein)
4.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRILVVEDDKDLNRQISVALEDAGYVVDRAFDGEEGHFLGDTEPYDAIVLDIGLPQMDGI
CEEEEEECCCCCCCEEEEEEECCCEEEEECCCCCCCCCCCCCCCCCEEEEECCCCCCCCH
SVLERWRRDGRKMPVLILTARDRWSDKVAGIDAGADDYVTKPFHMEEVLARVRALIRRAA
HHHHHHHHCCCCCCEEEEECCCCCCCHHCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHC
GHASSELYCGPLRLDTKASKADMDGVPLKLTSHEYRMLAYLMHHKGSVVSRTELVEHLYD
CCCCCCEEECCEEECCCCCCCCCCCCCEEECCHHHHHHHHHHHHCCCHHHHHHHHHHHHH
QDFDRDSNTIEVFVGRLRKKLGVDLIETVRGMGYRMREPNDG
CCCCCCCCHHHHHHHHHHHHHCHHHHHHHHCCCEECCCCCCC
>Mature Secondary Structure
MRILVVEDDKDLNRQISVALEDAGYVVDRAFDGEEGHFLGDTEPYDAIVLDIGLPQMDGI
CEEEEEECCCCCCCEEEEEEECCCEEEEECCCCCCCCCCCCCCCCCEEEEECCCCCCCCH
SVLERWRRDGRKMPVLILTARDRWSDKVAGIDAGADDYVTKPFHMEEVLARVRALIRRAA
HHHHHHHHCCCCCCEEEEECCCCCCCHHCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHC
GHASSELYCGPLRLDTKASKADMDGVPLKLTSHEYRMLAYLMHHKGSVVSRTELVEHLYD
CCCCCCEEECCEEECCCCCCCCCCCCCEEECCHHHHHHHHHHHHCCCHHHHHHHHHHHHH
QDFDRDSNTIEVFVGRLRKKLGVDLIETVRGMGYRMREPNDG
CCCCCCCCHHHHHHHHHHHHHCHHHHHHHHCCCEECCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11677608; 12644504 [H]