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The map label for this gene is barA [C]

Identifier: 110633234

GI number: 110633234

Start: 969421

End: 971067

Strand: Direct

Name: barA [C]

Synonym: Meso_0877

Alternate gene names: 110633234

Gene position: 969421-971067 (Clockwise)

Preceding gene: 110633231

Following gene: 110633235

Centisome position: 21.97

GC content: 64.06

Gene sequence:

>1647_bases
ATGCTTGCAGCGCTCGCGACGGCCGAAATCGCTGCCCGGCAGATGGGCTTGACCAGCGCCCTTTCGGCGGCCGCCCTGGT
GTTCGGTGTGGGTCTGTTGCCACCGCTTGTGCTCATCACCACCGCAAAGAGAAGAATTGCCGAGGCTTTGGCGCTATCGC
TTGGGGCGGTCACGCTCGGTGCTCTGATCGCCAGGAGCGGGGGCGCGATTTCGCCGCTGGTCGTCATGAGCGCCGGTTTC
GTCGTCGAGGCGGCCTGGCTCGGCAGAACGCGGCGGGCAATTGTGTTCGGCTCATCGGCGGCCGCCGTTGCGATCGGCCT
CGGTGTTGCGTTGACTGCCTTGAGCGGGACGGATTTGCCCTCTGCCTGGCAATGGCTGGTGCCGCTCGTCTATGCGGCCA
CTCTCCTTGTGCGCTGGCCTTTTACCGGACCAGCCGAAGGGCAGGTCTCGAGCGAAACGCCGGGCCTGGCGCTGGAGGAG
ATGATCGGTGCGGCAGTCCTGCGCCTGCAGGTCTCCGGCGATGTCGTCCATGCATCGCCGAAGCTGGAGGAAGTTTTGGG
CGTAGCCCCGGAAATGCTTCTGGGAACCGGCTTCTTCGACCGTATCCACGTGACCGATCGTGTCGCCTGGCTTTCGACGC
TCGGCGACCTCCGCGAGGGCGCCGGCCCCCGAACGCTTCGTCTTCGCCTCCGTGTCCCGGCCGCGCCCGGGCTTCCGATC
CAAGCGGCCTATCGCAGCTTCATATTCGATGTCGCTGCCCTGCAGGATGCGGCCGGCGTGGTCGCCCTGTTGCGCGAAGA
CGTCAGCACCGCCGCGGCAGAGGAGGCGCTTGCCGAGGCGAGACATGTTGCGGAAGCGGCCTGCCGCTCCAGGGACGAGA
TGCTTGCCTCCGTCAGCCATGAACTGCGCACGCCGCTCAACGCGATCGTCGGCTTTGCGGACCTGCTGGCGAACGAGATG
TTCGGCAAATTCGCCAATGACAAGCAGCGCGAATATGTGGAGGTGATCCGGGAGGCAGGCACTCATCTGCTCTCGGTGGT
GAACGCGATCCTCGATGTTTCCAAGGTGCAATCTGGCGCCTATGGGGTGGAGGCCAAACCGTTCCATTTCGAGGACGCGG
TGCGCCTTTGCATGGCCATGACGACGCATCAGGCGCAGGCGAAGTCGGTGGAACTGAAAGCTGATATTGCCGGGGATATC
GGCACCGTGCGTTGCGACAAGAACGCCGTGCAGCAGGTCCTCATCAATCTCTTGTCCAATGCCGTGAAGTTTACACCCTC
CGGCGAGGTGAAGGTCACGGCGCATCGCAGCGGCGACCGTCTGGAGTTTACCGTCAGCGATACCGGTATCGGAATCTCCG
CCGAGGATCTGGAACTGGTCGGCACCCCTTTCATGCAGGTGCGCAATGATTATACGCGCAAATGCGAAGGCACGGGGCTC
GGCCTTGCGCTGGTGAAGGGCCTGGTCAGGCTGCAAGGCGGCGGCCTGAGCATCGAAAGCGCTCCAGGCCGGGGCACGCG
GGTTCACGTTTCCTTGCCCGCCGGCCCGGCCGACGCTTGTCGGGAAGTGGAGGATTCGAGCTTCGCTGCGAGCGGGGCGA
ATTATAATCGCGAGTGGTATGATGACGCGTTACGCAAAACGGCCTAG

Upstream 100 bases:

>100_bases
ATTGAAGGCCGCTTGCGAGCGCCTGCTGCACCCCTCTGTCGAAACCGGAGAGGAGCGGGCGCGGCAAGCGCGCCTCCTCG
GGATATTGCTTGCAGCGCCC

Downstream 100 bases:

>100_bases
GTCGCGGGCTGGCGCGAGGGGAAAGCGCACCGGCTGGCTGCGGGCCGGTATCTCCGGTGCTGCCGCCGCGGCCGGGCGCA
ATCCGGTGGCCGTCGGCGGC

Product: multi-sensor signal transduction histidine kinase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 548; Mature: 548

Protein sequence:

>548_residues
MLAALATAEIAARQMGLTSALSAAALVFGVGLLPPLVLITTAKRRIAEALALSLGAVTLGALIARSGGAISPLVVMSAGF
VVEAAWLGRTRRAIVFGSSAAAVAIGLGVALTALSGTDLPSAWQWLVPLVYAATLLVRWPFTGPAEGQVSSETPGLALEE
MIGAAVLRLQVSGDVVHASPKLEEVLGVAPEMLLGTGFFDRIHVTDRVAWLSTLGDLREGAGPRTLRLRLRVPAAPGLPI
QAAYRSFIFDVAALQDAAGVVALLREDVSTAAAEEALAEARHVAEAACRSRDEMLASVSHELRTPLNAIVGFADLLANEM
FGKFANDKQREYVEVIREAGTHLLSVVNAILDVSKVQSGAYGVEAKPFHFEDAVRLCMAMTTHQAQAKSVELKADIAGDI
GTVRCDKNAVQQVLINLLSNAVKFTPSGEVKVTAHRSGDRLEFTVSDTGIGISAEDLELVGTPFMQVRNDYTRKCEGTGL
GLALVKGLVRLQGGGLSIESAPGRGTRVHVSLPAGPADACREVEDSSFAASGANYNREWYDDALRKTA

Sequences:

>Translated_548_residues
MLAALATAEIAARQMGLTSALSAAALVFGVGLLPPLVLITTAKRRIAEALALSLGAVTLGALIARSGGAISPLVVMSAGF
VVEAAWLGRTRRAIVFGSSAAAVAIGLGVALTALSGTDLPSAWQWLVPLVYAATLLVRWPFTGPAEGQVSSETPGLALEE
MIGAAVLRLQVSGDVVHASPKLEEVLGVAPEMLLGTGFFDRIHVTDRVAWLSTLGDLREGAGPRTLRLRLRVPAAPGLPI
QAAYRSFIFDVAALQDAAGVVALLREDVSTAAAEEALAEARHVAEAACRSRDEMLASVSHELRTPLNAIVGFADLLANEM
FGKFANDKQREYVEVIREAGTHLLSVVNAILDVSKVQSGAYGVEAKPFHFEDAVRLCMAMTTHQAQAKSVELKADIAGDI
GTVRCDKNAVQQVLINLLSNAVKFTPSGEVKVTAHRSGDRLEFTVSDTGIGISAEDLELVGTPFMQVRNDYTRKCEGTGL
GLALVKGLVRLQGGGLSIESAPGRGTRVHVSLPAGPADACREVEDSSFAASGANYNREWYDDALRKTA
>Mature_548_residues
MLAALATAEIAARQMGLTSALSAAALVFGVGLLPPLVLITTAKRRIAEALALSLGAVTLGALIARSGGAISPLVVMSAGF
VVEAAWLGRTRRAIVFGSSAAAVAIGLGVALTALSGTDLPSAWQWLVPLVYAATLLVRWPFTGPAEGQVSSETPGLALEE
MIGAAVLRLQVSGDVVHASPKLEEVLGVAPEMLLGTGFFDRIHVTDRVAWLSTLGDLREGAGPRTLRLRLRVPAAPGLPI
QAAYRSFIFDVAALQDAAGVVALLREDVSTAAAEEALAEARHVAEAACRSRDEMLASVSHELRTPLNAIVGFADLLANEM
FGKFANDKQREYVEVIREAGTHLLSVVNAILDVSKVQSGAYGVEAKPFHFEDAVRLCMAMTTHQAQAKSVELKADIAGDI
GTVRCDKNAVQQVLINLLSNAVKFTPSGEVKVTAHRSGDRLEFTVSDTGIGISAEDLELVGTPFMQVRNDYTRKCEGTGL
GLALVKGLVRLQGGGLSIESAPGRGTRVHVSLPAGPADACREVEDSSFAASGANYNREWYDDALRKTA

Specific function: Member Of The Two-Component Regulatory System Uvry/Bara Involved In The Regulation Of Carbon Metabolism Via The Csra/Csrb Regulatory System. Phosphorylates Uvry, Probably Via A Four-Step Phosphorelay. [C]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 PAC (PAS-associated C-terminal) domain [H]

Homologues:

Organism=Escherichia coli, GI1789149, Length=260, Percent_Identity=33.0769230769231, Blast_Score=144, Evalue=2e-35,
Organism=Escherichia coli, GI145693157, Length=249, Percent_Identity=35.7429718875502, Blast_Score=142, Evalue=5e-35,
Organism=Escherichia coli, GI48994928, Length=245, Percent_Identity=31.4285714285714, Blast_Score=120, Evalue=2e-28,
Organism=Escherichia coli, GI87081816, Length=238, Percent_Identity=33.6134453781513, Blast_Score=118, Evalue=1e-27,
Organism=Escherichia coli, GI1788713, Length=256, Percent_Identity=32.03125, Blast_Score=116, Evalue=4e-27,
Organism=Escherichia coli, GI1786912, Length=262, Percent_Identity=27.8625954198473, Blast_Score=96, Evalue=4e-21,
Organism=Escherichia coli, GI1790436, Length=219, Percent_Identity=28.7671232876712, Blast_Score=95, Evalue=1e-20,
Organism=Escherichia coli, GI1786600, Length=238, Percent_Identity=30.2521008403361, Blast_Score=94, Evalue=3e-20,
Organism=Escherichia coli, GI1788549, Length=399, Percent_Identity=22.8070175438596, Blast_Score=87, Evalue=3e-18,
Organism=Escherichia coli, GI1786783, Length=223, Percent_Identity=29.5964125560538, Blast_Score=84, Evalue=3e-17,
Organism=Escherichia coli, GI87082128, Length=229, Percent_Identity=26.2008733624454, Blast_Score=79, Evalue=6e-16,
Organism=Escherichia coli, GI1790346, Length=233, Percent_Identity=26.1802575107296, Blast_Score=72, Evalue=1e-13,
Organism=Escherichia coli, GI1788393, Length=241, Percent_Identity=26.1410788381743, Blast_Score=72, Evalue=1e-13,
Organism=Escherichia coli, GI1789808, Length=268, Percent_Identity=25.7462686567164, Blast_Score=64, Evalue=2e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR001610
- InterPro:   IPR000700
- InterPro:   IPR004358
- InterPro:   IPR003661
- InterPro:   IPR005467
- InterPro:   IPR009082 [H]

Pfam domain/function: PF02518 HATPase_c; PF00512 HisKA [H]

EC number: =2.7.13.3 [H]

Molecular weight: Translated: 57573; Mature: 57573

Theoretical pI: Translated: 5.89; Mature: 5.89

Prosite motif: PS50112 PAS ; PS50109 HIS_KIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLAALATAEIAARQMGLTSALSAAALVFGVGLLPPLVLITTAKRRIAEALALSLGAVTLG
CCCHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
ALIARSGGAISPLVVMSAGFVVEAAWLGRTRRAIVFGSSAAAVAIGLGVALTALSGTDLP
HHHHCCCCCCCHHHHHHCCHHEEHHHHCCCCEEEEECCCHHHHHHHHHHHHHHCCCCCCC
SAWQWLVPLVYAATLLVRWPFTGPAEGQVSSETPGLALEEMIGAAVLRLQVSGDVVHASP
HHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCHHHHHHHHHHHEEEEECCCEEECCC
KLEEVLGVAPEMLLGTGFFDRIHVTDRVAWLSTLGDLREGAGPRTLRLRLRVPAAPGLPI
HHHHHHCCCHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEEECCCCCCCCH
QAAYRSFIFDVAALQDAAGVVALLREDVSTAAAEEALAEARHVAEAACRSRDEMLASVSH
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
ELRTPLNAIVGFADLLANEMFGKFANDKQREYVEVIREAGTHLLSVVNAILDVSKVQSGA
HHHCHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC
YGVEAKPFHFEDAVRLCMAMTTHQAQAKSVELKADIAGDIGTVRCDKNAVQQVLINLLSN
CCCCCCCCCHHHHHHHHHHHHHHHHHHHCEEEEEECCCCCCEEEECHHHHHHHHHHHHHH
AVKFTPSGEVKVTAHRSGDRLEFTVSDTGIGISAEDLELVGTPFMQVRNDYTRKCEGTGL
HEEECCCCCEEEEEECCCCEEEEEEECCCCCCCCCCHHHHCCCHHHHHHHHHHHCCCCCC
GLALVKGLVRLQGGGLSIESAPGRGTRVHVSLPAGPADACREVEDSSFAASGANYNREWY
HHHHHHHHHHCCCCCEEEECCCCCCCEEEEECCCCCHHHHHHCCCCCCCCCCCCCCHHHH
DDALRKTA
HHHHHHCC
>Mature Secondary Structure
MLAALATAEIAARQMGLTSALSAAALVFGVGLLPPLVLITTAKRRIAEALALSLGAVTLG
CCCHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
ALIARSGGAISPLVVMSAGFVVEAAWLGRTRRAIVFGSSAAAVAIGLGVALTALSGTDLP
HHHHCCCCCCCHHHHHHCCHHEEHHHHCCCCEEEEECCCHHHHHHHHHHHHHHCCCCCCC
SAWQWLVPLVYAATLLVRWPFTGPAEGQVSSETPGLALEEMIGAAVLRLQVSGDVVHASP
HHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCHHHHHHHHHHHEEEEECCCEEECCC
KLEEVLGVAPEMLLGTGFFDRIHVTDRVAWLSTLGDLREGAGPRTLRLRLRVPAAPGLPI
HHHHHHCCCHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEEECCCCCCCCH
QAAYRSFIFDVAALQDAAGVVALLREDVSTAAAEEALAEARHVAEAACRSRDEMLASVSH
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
ELRTPLNAIVGFADLLANEMFGKFANDKQREYVEVIREAGTHLLSVVNAILDVSKVQSGA
HHHCHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC
YGVEAKPFHFEDAVRLCMAMTTHQAQAKSVELKADIAGDIGTVRCDKNAVQQVLINLLSN
CCCCCCCCCHHHHHHHHHHHHHHHHHHHCEEEEEECCCCCCEEEECHHHHHHHHHHHHHH
AVKFTPSGEVKVTAHRSGDRLEFTVSDTGIGISAEDLELVGTPFMQVRNDYTRKCEGTGL
HEEECCCCCEEEEEECCCCEEEEEEECCCCCCCCCCHHHHCCCHHHHHHHHHHHCCCCCC
GLALVKGLVRLQGGGLSIESAPGRGTRVHVSLPAGPADACREVEDSSFAASGANYNREWY
HHHHHHHHHHCCCCCEEEECCCCCCCEEEEECCCCCHHHHHHCCCCCCCCCCCCCCHHHH
DDALRKTA
HHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 11481430; 7756693 [H]