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The map label for this gene is pqqL [C]

Identifier: 110633116

GI number: 110633116

Start: 833501

End: 834793

Strand: Reverse

Name: pqqL [C]

Synonym: Meso_0759

Alternate gene names: 110633116

Gene position: 834793-833501 (Counterclockwise)

Preceding gene: 229259627

Following gene: 110633115

Centisome position: 18.92

GC content: 63.34

Gene sequence:

>1293_bases
ATGGGCGTAGAAGTGAGCCGTCTTTCGAACGGCTTGACGGTGGCAACCGAAACTCTTCCGCATCTTGAATCGGTTGCTTT
GGGCGTGTGGGTGAAATCCGGATCGCGGAACGAGCGGGAAGACGAACACGGCATTGCCCATCTGCTCGAGCACATGGCCT
TCAAGGGCACAACGAAGCGCACGGCCCTTCAAATCGCAACTGACATCGAGGATGTGGGCGGGGAGATAAACGCCGCCACC
AGCGTGGAAACCACGGCTTTCTATGCCAGGGTGCTGAGGGACGACATGTCGCTTGCCATCGACATCTTGGCCGACATCCT
CACCGATTCCAAATTCGATCCGCACGAGCTCGAACGCGAGCAGCACGTGATCCTGCAGGAAATCGGCGCCGCCCACGACA
CGCCGGACGATGCGGTTTTCGACCGTTTCACCGAGACCGCTTTCCGCCACCAGGCGATCGGCCGCTCAATCCTCGGCACG
CCGGACACGGTGGCGTCCTTCACGTCCCAACAGCTCCGCCGCTTCATGGAGCGCCAGTACGGCGCCGACCGCATGGTCGT
GGTCGCGGCGGGTGGTGTGACCCATGACGAATTCGTGCGGGAGGTGGAGGCTAGGCTGGGCAGCTTCCGCGACAAGGCGG
ATACGGCCGTTCCGCAATATTCCAACTATGTGGGCGGGGACTACCGCGAGCACCGCGATCTGATGGACGCCCAGATCATC
CTCGGATTCGAGGGCCGCGCCTATCATGTGCGCGACTTCTATGCCTCGCAGATGCTGTCGATGATCCTCGGCGGCGGCAT
GTCCTCGCGCCTCTTCCAGGAAGTCCGCGAGAAGCGGGGGCTCTGCTACTCGGTCTATGCCTTCCATTGGGGCTTTTCGG
ACACCGGCGTCTTCGGCGTCCACGCCGCGACCGGGCAGAGCGACCTGGGCGAACTCATGCCTGTGATCCTGGGAGAACTG
CAGAAGGCCGGCGAGAGAATCGATCAGGCGGAACTCGACCGCGCGCGGGCGCAGTATCGCGCCGGCCTCATGATGTCGCG
CGAGAGCCCCGCCAGCCGCGCATCGCAGGTCGCGCGTCAGCTTCTGCTCTATGGCAGGCCCATCGAGACGGAAGAACTCA
TGGATCGCCTTGCGGGTATCACCGTCGAGCGGCTGGCGGATCTTTCCAACCGCCTTTTCTCCTCAAAGCCGACCGTCACG
GCGATCGGGCCGGTGGGGTCGCTCGCACCCTTCGAGGCCATCCGCGATACGCTGGTAACTTCGCGTCCGGTGCTGCGCAA
GCTCGCCGTCTAA

Upstream 100 bases:

>100_bases
AGAGCACGGAGACTTACACGGTCCTTCCCTCGGACCTGAAAATGGTGGAAGATCACATCAGCCGCCACGCAAGGGCGGAA
GGATAGAAAGCGAGTAACAT

Downstream 100 bases:

>100_bases
CTGCCCGCGCCCGCATGTTTCACTTTCCCTTCTCTCGCCGAGGCCTGCCGGCGCTTGAGGGCCCGAGAGTGCGGCTTCGC
ATGCCGATGGGGCGCGACTA

Product: peptidase M16-like

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 430; Mature: 429

Protein sequence:

>430_residues
MGVEVSRLSNGLTVATETLPHLESVALGVWVKSGSRNEREDEHGIAHLLEHMAFKGTTKRTALQIATDIEDVGGEINAAT
SVETTAFYARVLRDDMSLAIDILADILTDSKFDPHELEREQHVILQEIGAAHDTPDDAVFDRFTETAFRHQAIGRSILGT
PDTVASFTSQQLRRFMERQYGADRMVVVAAGGVTHDEFVREVEARLGSFRDKADTAVPQYSNYVGGDYREHRDLMDAQII
LGFEGRAYHVRDFYASQMLSMILGGGMSSRLFQEVREKRGLCYSVYAFHWGFSDTGVFGVHAATGQSDLGELMPVILGEL
QKAGERIDQAELDRARAQYRAGLMMSRESPASRASQVARQLLLYGRPIETEELMDRLAGITVERLADLSNRLFSSKPTVT
AIGPVGSLAPFEAIRDTLVTSRPVLRKLAV

Sequences:

>Translated_430_residues
MGVEVSRLSNGLTVATETLPHLESVALGVWVKSGSRNEREDEHGIAHLLEHMAFKGTTKRTALQIATDIEDVGGEINAAT
SVETTAFYARVLRDDMSLAIDILADILTDSKFDPHELEREQHVILQEIGAAHDTPDDAVFDRFTETAFRHQAIGRSILGT
PDTVASFTSQQLRRFMERQYGADRMVVVAAGGVTHDEFVREVEARLGSFRDKADTAVPQYSNYVGGDYREHRDLMDAQII
LGFEGRAYHVRDFYASQMLSMILGGGMSSRLFQEVREKRGLCYSVYAFHWGFSDTGVFGVHAATGQSDLGELMPVILGEL
QKAGERIDQAELDRARAQYRAGLMMSRESPASRASQVARQLLLYGRPIETEELMDRLAGITVERLADLSNRLFSSKPTVT
AIGPVGSLAPFEAIRDTLVTSRPVLRKLAV
>Mature_429_residues
GVEVSRLSNGLTVATETLPHLESVALGVWVKSGSRNEREDEHGIAHLLEHMAFKGTTKRTALQIATDIEDVGGEINAATS
VETTAFYARVLRDDMSLAIDILADILTDSKFDPHELEREQHVILQEIGAAHDTPDDAVFDRFTETAFRHQAIGRSILGTP
DTVASFTSQQLRRFMERQYGADRMVVVAAGGVTHDEFVREVEARLGSFRDKADTAVPQYSNYVGGDYREHRDLMDAQIIL
GFEGRAYHVRDFYASQMLSMILGGGMSSRLFQEVREKRGLCYSVYAFHWGFSDTGVFGVHAATGQSDLGELMPVILGELQ
KAGERIDQAELDRARAQYRAGLMMSRESPASRASQVARQLLLYGRPIETEELMDRLAGITVERLADLSNRLFSSKPTVTA
IGPVGSLAPFEAIRDTLVTSRPVLRKLAV

Specific function: Unknown

COG id: COG0612

COG function: function code R; Predicted Zn-dependent peptidases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase M16 family [H]

Homologues:

Organism=Homo sapiens, GI94538354, Length=431, Percent_Identity=30.6264501160093, Blast_Score=230, Evalue=2e-60,
Organism=Homo sapiens, GI46593007, Length=434, Percent_Identity=28.8018433179723, Blast_Score=189, Evalue=5e-48,
Organism=Homo sapiens, GI24308013, Length=449, Percent_Identity=26.0579064587973, Blast_Score=140, Evalue=2e-33,
Organism=Homo sapiens, GI50592988, Length=421, Percent_Identity=22.8028503562945, Blast_Score=112, Evalue=5e-25,
Organism=Escherichia coli, GI1787770, Length=213, Percent_Identity=25.8215962441315, Blast_Score=71, Evalue=1e-13,
Organism=Escherichia coli, GI2367164, Length=212, Percent_Identity=27.8301886792453, Blast_Score=65, Evalue=1e-11,
Organism=Caenorhabditis elegans, GI71999683, Length=403, Percent_Identity=30.7692307692308, Blast_Score=196, Evalue=3e-50,
Organism=Caenorhabditis elegans, GI17553678, Length=385, Percent_Identity=27.5324675324675, Blast_Score=156, Evalue=2e-38,
Organism=Caenorhabditis elegans, GI17510601, Length=449, Percent_Identity=25.1670378619154, Blast_Score=132, Evalue=3e-31,
Organism=Caenorhabditis elegans, GI17569737, Length=327, Percent_Identity=23.8532110091743, Blast_Score=84, Evalue=1e-16,
Organism=Caenorhabditis elegans, GI17555260, Length=254, Percent_Identity=24.4094488188976, Blast_Score=75, Evalue=6e-14,
Organism=Caenorhabditis elegans, GI32566323, Length=406, Percent_Identity=21.1822660098522, Blast_Score=70, Evalue=2e-12,
Organism=Caenorhabditis elegans, GI17570205, Length=406, Percent_Identity=21.1822660098522, Blast_Score=70, Evalue=2e-12,
Organism=Saccharomyces cerevisiae, GI6323192, Length=439, Percent_Identity=30.5239179954442, Blast_Score=225, Evalue=1e-59,
Organism=Saccharomyces cerevisiae, GI6321813, Length=415, Percent_Identity=24.0963855421687, Blast_Score=129, Evalue=6e-31,
Organism=Saccharomyces cerevisiae, GI6319426, Length=443, Percent_Identity=20.7674943566591, Blast_Score=97, Evalue=4e-21,
Organism=Saccharomyces cerevisiae, GI6325449, Length=193, Percent_Identity=30.0518134715026, Blast_Score=70, Evalue=6e-13,
Organism=Drosophila melanogaster, GI21357875, Length=425, Percent_Identity=29.4117647058824, Blast_Score=226, Evalue=3e-59,
Organism=Drosophila melanogaster, GI24646943, Length=425, Percent_Identity=29.4117647058824, Blast_Score=226, Evalue=3e-59,
Organism=Drosophila melanogaster, GI19921772, Length=451, Percent_Identity=24.6119733924612, Blast_Score=130, Evalue=2e-30,
Organism=Drosophila melanogaster, GI24665395, Length=423, Percent_Identity=26.241134751773, Blast_Score=97, Evalue=2e-20,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011249
- InterPro:   IPR011237
- InterPro:   IPR011765
- InterPro:   IPR001431
- InterPro:   IPR007863 [H]

Pfam domain/function: PF00675 Peptidase_M16; PF05193 Peptidase_M16_C [H]

EC number: 3.4.99.- [C]

Molecular weight: Translated: 47581; Mature: 47450

Theoretical pI: Translated: 5.34; Mature: 5.34

Prosite motif: PS00143 INSULINASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MGVEVSRLSNGLTVATETLPHLESVALGVWVKSGSRNEREDEHGIAHLLEHMAFKGTTKR
CCCCHHHHCCCCEEEHHHHHHHHHHHHHHEEECCCCCCCHHHHHHHHHHHHHHHCCCCHH
TALQIATDIEDVGGEINAATSVETTAFYARVLRDDMSLAIDILADILTDSKFDPHELERE
HHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHH
QHVILQEIGAAHDTPDDAVFDRFTETAFRHQAIGRSILGTPDTVASFTSQQLRRFMERQY
HHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHCHHHCCCCHHHHHHHHHHHHHHHHHHC
GADRMVVVAAGGVTHDEFVREVEARLGSFRDKADTAVPQYSNYVGGDYREHRDLMDAQII
CCCEEEEEEECCCCHHHHHHHHHHHHHCCHHHHHHCCCCHHCCCCCCHHHHHHHHCCEEE
LGFEGRAYHVRDFYASQMLSMILGGGMSSRLFQEVREKRGLCYSVYAFHWGFSDTGVFGV
EECCCCEEHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHCCCEEEEEEEECCCCCCCEEEE
HAATGQSDLGELMPVILGELQKAGERIDQAELDRARAQYRAGLMMSRESPASRASQVARQ
ECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHH
LLLYGRPIETEELMDRLAGITVERLADLSNRLFSSKPTVTAIGPVGSLAPFEAIRDTLVT
HHHCCCCCCHHHHHHHHHCCHHHHHHHHHHHHHCCCCCEEEECCCCCCCHHHHHHHHHHC
SRPVLRKLAV
CHHHHHHHCC
>Mature Secondary Structure 
GVEVSRLSNGLTVATETLPHLESVALGVWVKSGSRNEREDEHGIAHLLEHMAFKGTTKR
CCCHHHHCCCCEEEHHHHHHHHHHHHHHEEECCCCCCCHHHHHHHHHHHHHHHCCCCHH
TALQIATDIEDVGGEINAATSVETTAFYARVLRDDMSLAIDILADILTDSKFDPHELERE
HHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHH
QHVILQEIGAAHDTPDDAVFDRFTETAFRHQAIGRSILGTPDTVASFTSQQLRRFMERQY
HHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHCHHHCCCCHHHHHHHHHHHHHHHHHHC
GADRMVVVAAGGVTHDEFVREVEARLGSFRDKADTAVPQYSNYVGGDYREHRDLMDAQII
CCCEEEEEEECCCCHHHHHHHHHHHHHCCHHHHHHCCCCHHCCCCCCHHHHHHHHCCEEE
LGFEGRAYHVRDFYASQMLSMILGGGMSSRLFQEVREKRGLCYSVYAFHWGFSDTGVFGV
EECCCCEEHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHCCCEEEEEEEECCCCCCCEEEE
HAATGQSDLGELMPVILGELQKAGERIDQAELDRARAQYRAGLMMSRESPASRASQVARQ
ECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHH
LLLYGRPIETEELMDRLAGITVERLADLSNRLFSSKPTVTAIGPVGSLAPFEAIRDTLVT
HHHCCCCCCHHHHHHHHHCCHHHHHHHHHHHHHCCCCCEEEECCCCCCCHHHHHHHHHHC
SRPVLRKLAV
CHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: Zn [C]

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: Hydrolase; Acting on peptide bonds (Peptidases); Endopeptidases of unknown catalytic mechanism [C]

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA