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The map label for this gene is dacA [H]

Identifier: 110632991

GI number: 110632991

Start: 710672

End: 711535

Strand: Reverse

Name: dacA [H]

Synonym: Meso_0634

Alternate gene names: 110632991

Gene position: 711535-710672 (Counterclockwise)

Preceding gene: 110632992

Following gene: 110632990

Centisome position: 16.13

GC content: 57.29

Gene sequence:

>864_bases
TTGCGGATCGGGAGCTTGGCATTACCGCGACTTTTCTGGCTTGCCTTTATTGTCTTGCCCTTCGTGTCCGGTTGCGGATC
CACATCGGCTGTGGCTCCTCTTGTCCAACCGATAGAATCCGAAAAATACTCATCCATCGTGGTCGACGCCGGTTCTGGAG
AGATCCTTCACCAATATGCGGCGGATGCGCCACGCTATCCGGCATCGCTTACGAAGATGATGACCCTTTACCTCCTCTTC
GAGGCGATTGATTCCGGCATCCTGTCGCCAACCAGCAGGATTACCGCTTCGGCCTATGCCGCCTCCCGCCCTCCCAGCAA
GCTTGGCTTGAGGCCGGGAGACTCCTTCGATGTCCAGACGGCCATACTAGCGCTGTGCGTGAAATCCGCAAATGATGTGG
CTGCCGCCGTGGCGGAGCATCTGGGGGGAACCGAGCAGCAATTTGCCGGCATGATGACTGCCAAGGCCCGGCAGCTCGGT
ATGAGATCCACGGTGTTCACCAATGCTTCGGGACTGCCTGATTCAGGCCAGATGACCACCGCACGTGACATGGCGTTGCT
TGCTCTGGCGCTGCATAACCGGTTTCCCCATCATTATCATGTCTTTGCCAATCAAAGCTTTGCCCATGAGGGAAGAACCA
TCAAAGGACATAACGATTTGCTCGGGCGTGTGGATGGCGTGGACGGGATCAAGACGGGCTATATCCGCGCATCCGGCTAC
AACATAGCCACGTCCGCTGCACGCGGACGCAAGCGAATTGTCGTGATTGTGATGGGAGGCGACACCGCGAGATCGCGAAA
TGCACATGTCGAACGCCTCCTGGAAGCCTACCTGCCACAGGCCGGATTTGCCGCAATTCGATAG

Upstream 100 bases:

>100_bases
CATGAAGCAGCGTGAATATCTTCTGAGCAACCGGCACCGCGGGCTTGGTTTCCCTGCGCGGAATGGCAAAGTATAGCGGA
CGAAGGATGGGGGTTATCAA

Downstream 100 bases:

>100_bases
AGCTTTTGGCATCGCCAAGGGGCTGCTGGAGCGTTTGCGGCGAGCCCTCGCGGCGTCACGCATTGTTATGGACTGAAAAG
CAGTGTTACTATACTCTTCG

Product: peptidase S11, D-alanyl-D-alanine carboxypeptidase 1

Products: NA

Alternate protein names: DD-carboxypeptidase; DD-peptidase; Penicillin-binding protein 5; PBP-5 [H]

Number of amino acids: Translated: 287; Mature: 287

Protein sequence:

>287_residues
MRIGSLALPRLFWLAFIVLPFVSGCGSTSAVAPLVQPIESEKYSSIVVDAGSGEILHQYAADAPRYPASLTKMMTLYLLF
EAIDSGILSPTSRITASAYAASRPPSKLGLRPGDSFDVQTAILALCVKSANDVAAAVAEHLGGTEQQFAGMMTAKARQLG
MRSTVFTNASGLPDSGQMTTARDMALLALALHNRFPHHYHVFANQSFAHEGRTIKGHNDLLGRVDGVDGIKTGYIRASGY
NIATSAARGRKRIVVIVMGGDTARSRNAHVERLLEAYLPQAGFAAIR

Sequences:

>Translated_287_residues
MRIGSLALPRLFWLAFIVLPFVSGCGSTSAVAPLVQPIESEKYSSIVVDAGSGEILHQYAADAPRYPASLTKMMTLYLLF
EAIDSGILSPTSRITASAYAASRPPSKLGLRPGDSFDVQTAILALCVKSANDVAAAVAEHLGGTEQQFAGMMTAKARQLG
MRSTVFTNASGLPDSGQMTTARDMALLALALHNRFPHHYHVFANQSFAHEGRTIKGHNDLLGRVDGVDGIKTGYIRASGY
NIATSAARGRKRIVVIVMGGDTARSRNAHVERLLEAYLPQAGFAAIR
>Mature_287_residues
MRIGSLALPRLFWLAFIVLPFVSGCGSTSAVAPLVQPIESEKYSSIVVDAGSGEILHQYAADAPRYPASLTKMMTLYLLF
EAIDSGILSPTSRITASAYAASRPPSKLGLRPGDSFDVQTAILALCVKSANDVAAAVAEHLGGTEQQFAGMMTAKARQLG
MRSTVFTNASGLPDSGQMTTARDMALLALALHNRFPHHYHVFANQSFAHEGRTIKGHNDLLGRVDGVDGIKTGYIRASGY
NIATSAARGRKRIVVIVMGGDTARSRNAHVERLLEAYLPQAGFAAIR

Specific function: Removes C-terminal D-alanyl residues from sugar-peptide cell wall precursors [H]

COG id: COG1686

COG function: function code M; D-alanyl-D-alanine carboxypeptidase

Gene ontology:

Cell location: Cell inner membrane; Peripheral membrane protein. Note=N-terminal lies in the periplasmic space (By similarity) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase S11 family [H]

Homologues:

Organism=Escherichia coli, GI1786851, Length=249, Percent_Identity=36.144578313253, Blast_Score=153, Evalue=1e-38,
Organism=Escherichia coli, GI87082022, Length=246, Percent_Identity=34.9593495934959, Blast_Score=146, Evalue=2e-36,
Organism=Escherichia coli, GI1787062, Length=236, Percent_Identity=35.1694915254237, Blast_Score=142, Evalue=3e-35,
Organism=Escherichia coli, GI87082054, Length=264, Percent_Identity=25, Blast_Score=62, Evalue=4e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR012338
- InterPro:   IPR015956
- InterPro:   IPR018044
- InterPro:   IPR012907
- InterPro:   IPR001967 [H]

Pfam domain/function: PF07943 PBP5_C; PF00768 Peptidase_S11 [H]

EC number: =3.4.16.4 [H]

Molecular weight: Translated: 30632; Mature: 30632

Theoretical pI: Translated: 9.86; Mature: 9.86

Prosite motif: PS00013 PROKAR_LIPOPROTEIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
3.1 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
3.1 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRIGSLALPRLFWLAFIVLPFVSGCGSTSAVAPLVQPIESEKYSSIVVDAGSGEILHQYA
CCCCHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHCCCCCCEEEEECCCCHHHHHHH
ADAPRYPASLTKMMTLYLLFEAIDSGILSPTSRITASAYAASRPPSKLGLRPGDSFDVQT
CCCCCCCHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHCCCCCHHCCCCCCCCCHHHH
AILALCVKSANDVAAAVAEHLGGTEQQFAGMMTAKARQLGMRSTVFTNASGLPDSGQMTT
HHHHHHHHCCHHHHHHHHHHCCCCHHHHHHHHHHHHHHHCCHHHEEECCCCCCCCCCCCH
ARDMALLALALHNRFPHHYHVFANQSFAHEGRTIKGHNDLLGRVDGVDGIKTGYIRASGY
HHHHHHHHHHHHHCCCCEEEEEECCCHHHCCCEECCCHHHHHHCCCCCCCCCCEEEECCC
NIATSAARGRKRIVVIVMGGDTARSRNAHVERLLEAYLPQAGFAAIR
CEEHHHCCCCCEEEEEEECCCCCCCCHHHHHHHHHHHCCCCCCCCCC
>Mature Secondary Structure
MRIGSLALPRLFWLAFIVLPFVSGCGSTSAVAPLVQPIESEKYSSIVVDAGSGEILHQYA
CCCCHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHCCCCCCEEEEECCCCHHHHHHH
ADAPRYPASLTKMMTLYLLFEAIDSGILSPTSRITASAYAASRPPSKLGLRPGDSFDVQT
CCCCCCCHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHCCCCCHHCCCCCCCCCHHHH
AILALCVKSANDVAAAVAEHLGGTEQQFAGMMTAKARQLGMRSTVFTNASGLPDSGQMTT
HHHHHHHHCCHHHHHHHHHHCCCCHHHHHHHHHHHHHHHCCHHHEEECCCCCCCCCCCCH
ARDMALLALALHNRFPHHYHVFANQSFAHEGRTIKGHNDLLGRVDGVDGIKTGYIRASGY
HHHHHHHHHHHHHCCCCEEEEEECCCHHHCCCEECCCHHHHHHCCCCCCCCCCEEEECCC
NIATSAARGRKRIVVIVMGGDTARSRNAHVERLLEAYLPQAGFAAIR
CEEHHHCCCCCEEEEEEECCCCCCCCHHHHHHHHHHHCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]