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The map label for this gene is prtE [H]

Identifier: 110632974

GI number: 110632974

Start: 691497

End: 692795

Strand: Reverse

Name: prtE [H]

Synonym: Meso_0617

Alternate gene names: 110632974

Gene position: 692795-691497 (Counterclockwise)

Preceding gene: 110632975

Following gene: 110632973

Centisome position: 15.7

GC content: 63.66

Gene sequence:

>1299_bases
ATGGAATGGCATGCAGGCGTGAAGACCGGGTTCACCGGGCCATTTATCGCTGGACTGGTGAGCCTGACCGCAGGACTGGG
CGGCTTTGCCACCTGGGCAGCGCTGGCGCCCCTGGAGGGAGCCGTCATCGCACCTGGAAAGGTGGTCGTGCAGGGGCGCA
ACAAGACCGTTCAGCATCTGGAAGGCGGAATCGTCAAGACGATCCTCGTCGAGGACGGCGAGAATGTGGAGGCAGGCGAT
CCTCTCCTCGTGCTCGATGGCACCGCCGCGAAATCGGCGGCGGACCGGCTGCGCGCCCAATTGGCCGCTATCGAGGCCAC
GGAGGCCAGAGCCCTCGCCGAGCGGGAGAGCGCCAAGTCCATATCTTTCCCGGCCCATCTACTCGCTTCTCAGAAACCGG
AGATCGTGCGCCTTCTGGCGGACCAGGAGGCCGAATTTGACTTCCGGCTGCGCGAGCACGGAGCCGAAATCGCGACGTTC
GAACTGCAGATCGCCGCGCTGGAGGCTCAGATCGCCGGCCATACGGTTCAGCAGGAAGAAACGGCGCGGCAGCTTGAATT
GCTGGTCGAGGAACGGCAGGCATTGGAAACCCTGCTTGCCAAAGGGCTGACCCGCAAGAGCCAAGTTCTGGCGCTGAAGC
GCAACGAAGCCGAACTTCATGGCCGCCAGGGCCAGCTTGCCGCGGCGATTGCGGAATCGCGCCGCACCATGGCGGAAATC
CGTGAGCGCATTGAACAGGTCCGCTCGGCTCGCACCAGCAAGGCCTCGGCCCAGCTCAGCGAGCTTCGGCTAAAACGCGC
GGAAGTGCTGGAGCAGCTGCGCGCGGCAGAGGACGTCAGCGGCAGGCTCGTCGTGCGCGCGCCGGCTTCGGGAACCGTCA
TCAACCTGGCCAAGTACAATCCGGGCGCCGTTATCGCTCCGGGCGAAGATCTGATGTCCATCGTGCCGGAAGAAAGCGGT
CTGGTCGTGGAGGCGCGGATCAGGCCGCTCGATATAGACGAGATCAGGGTTGGCCAGGAAGCACGCCTCAATTTCTCGGC
TTTCGATGCACGGCAAACGCCGCCGATCGAAACCAAGGTGGTCTATCTTTCGGCAGACCGGTTCGAGAGCGAGCGCGGCG
AACCTTACTATATCGCCCGGCTCGAAATCCCGGCCGGCTCCGGCGCTGGTTTTGACCCGTCGAAAATCGGACCCGGGCAG
GAGGCTGAGGTCTTCATCACCACGGGTGAGCGAACCTTCTTCGGCTATATCGCCGCCCCTCTCATGAAAACACTCTCCCG
GTCCGTCCGGGAGAGCTGA

Upstream 100 bases:

>100_bases
CCCTCGCCTGAGGCGTCGAAAATTCCCGCCACAAACCCGGCCACCGGCTCTCCGCTCGTGACCGCGCGGTTCGGCTGACG
CATTGGACAGGATCAAAAAG

Downstream 100 bases:

>100_bases
GCACCACTTGACCCAAGCAGAGTAGAGAAAACAAATGCCCGCAACCGCCACCTATAATCTGACCGGCAACGCCTATATCG
ACGGCTTGCTGAGTGGAATC

Product: HlyD family type I secretion membrane fusion protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 432; Mature: 432

Protein sequence:

>432_residues
MEWHAGVKTGFTGPFIAGLVSLTAGLGGFATWAALAPLEGAVIAPGKVVVQGRNKTVQHLEGGIVKTILVEDGENVEAGD
PLLVLDGTAAKSAADRLRAQLAAIEATEARALAERESAKSISFPAHLLASQKPEIVRLLADQEAEFDFRLREHGAEIATF
ELQIAALEAQIAGHTVQQEETARQLELLVEERQALETLLAKGLTRKSQVLALKRNEAELHGRQGQLAAAIAESRRTMAEI
RERIEQVRSARTSKASAQLSELRLKRAEVLEQLRAAEDVSGRLVVRAPASGTVINLAKYNPGAVIAPGEDLMSIVPEESG
LVVEARIRPLDIDEIRVGQEARLNFSAFDARQTPPIETKVVYLSADRFESERGEPYYIARLEIPAGSGAGFDPSKIGPGQ
EAEVFITTGERTFFGYIAAPLMKTLSRSVRES

Sequences:

>Translated_432_residues
MEWHAGVKTGFTGPFIAGLVSLTAGLGGFATWAALAPLEGAVIAPGKVVVQGRNKTVQHLEGGIVKTILVEDGENVEAGD
PLLVLDGTAAKSAADRLRAQLAAIEATEARALAERESAKSISFPAHLLASQKPEIVRLLADQEAEFDFRLREHGAEIATF
ELQIAALEAQIAGHTVQQEETARQLELLVEERQALETLLAKGLTRKSQVLALKRNEAELHGRQGQLAAAIAESRRTMAEI
RERIEQVRSARTSKASAQLSELRLKRAEVLEQLRAAEDVSGRLVVRAPASGTVINLAKYNPGAVIAPGEDLMSIVPEESG
LVVEARIRPLDIDEIRVGQEARLNFSAFDARQTPPIETKVVYLSADRFESERGEPYYIARLEIPAGSGAGFDPSKIGPGQ
EAEVFITTGERTFFGYIAAPLMKTLSRSVRES
>Mature_432_residues
MEWHAGVKTGFTGPFIAGLVSLTAGLGGFATWAALAPLEGAVIAPGKVVVQGRNKTVQHLEGGIVKTILVEDGENVEAGD
PLLVLDGTAAKSAADRLRAQLAAIEATEARALAERESAKSISFPAHLLASQKPEIVRLLADQEAEFDFRLREHGAEIATF
ELQIAALEAQIAGHTVQQEETARQLELLVEERQALETLLAKGLTRKSQVLALKRNEAELHGRQGQLAAAIAESRRTMAEI
RERIEQVRSARTSKASAQLSELRLKRAEVLEQLRAAEDVSGRLVVRAPASGTVINLAKYNPGAVIAPGEDLMSIVPEESG
LVVEARIRPLDIDEIRVGQEARLNFSAFDARQTPPIETKVVYLSADRFESERGEPYYIARLEIPAGSGAGFDPSKIGPGQ
EAEVFITTGERTFFGYIAAPLMKTLSRSVRES

Specific function: Involved in the secretion of proteases A, B, C and G [H]

COG id: COG0845

COG function: function code M; Membrane-fusion protein

Gene ontology:

Cell location: Cell inner membrane; Single-pass membrane protein [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003997
- InterPro:   IPR006143
- InterPro:   IPR006144
- InterPro:   IPR010129 [H]

Pfam domain/function: PF00529 HlyD [H]

EC number: NA

Molecular weight: Translated: 46633; Mature: 46633

Theoretical pI: Translated: 5.19; Mature: 5.19

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
0.9 %Met     (Translated Protein)
0.9 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
0.9 %Met     (Mature Protein)
0.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MEWHAGVKTGFTGPFIAGLVSLTAGLGGFATWAALAPLEGAVIAPGKVVVQGRNKTVQHL
CCCCCCCCCCCCHHHHHHHHHHHHCCCHHHHHHHHCCCCCCEECCCEEEEECCCCHHHHH
EGGIVKTILVEDGENVEAGDPLLVLDGTAAKSAADRLRAQLAAIEATEARALAERESAKS
CCCEEEEEEEECCCCCCCCCCEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC
ISFPAHLLASQKPEIVRLLADQEAEFDFRLREHGAEIATFELQIAALEAQIAGHTVQQEE
CCCCHHHHCCCCCHHHHHHHCCCCCCCHHHHHCCCEEEEEEEEEEEEHHHHHCCCHHHHH
TARQLELLVEERQALETLLAKGLTRKSQVLALKRNEAELHGRQGQLAAAIAESRRTMAEI
HHHHHHHHHHHHHHHHHHHHHCCCCCHHEEEEECCCHHHCCCCCHHHHHHHHHHHHHHHH
RERIEQVRSARTSKASAQLSELRLKRAEVLEQLRAAEDVSGRLVVRAPASGTVINLAKYN
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEECCCCCEEEEEECC
PGAVIAPGEDLMSIVPEESGLVVEARIRPLDIDEIRVGQEARLNFSAFDARQTPPIETKV
CCEEEECCHHHHHHCCCCCCEEEEEECCCCCHHHHCCCCHHCCCEEEECCCCCCCCCEEE
VYLSADRFESERGEPYYIARLEIPAGSGAGFDPSKIGPGQEAEVFITTGERTFFGYIAAP
EEEECCCCCCCCCCEEEEEEEEECCCCCCCCCCCCCCCCCCCEEEEEECCCHHHHHHHHH
LMKTLSRSVRES
HHHHHHHHHHCC
>Mature Secondary Structure
MEWHAGVKTGFTGPFIAGLVSLTAGLGGFATWAALAPLEGAVIAPGKVVVQGRNKTVQHL
CCCCCCCCCCCCHHHHHHHHHHHHCCCHHHHHHHHCCCCCCEECCCEEEEECCCCHHHHH
EGGIVKTILVEDGENVEAGDPLLVLDGTAAKSAADRLRAQLAAIEATEARALAERESAKS
CCCEEEEEEEECCCCCCCCCCEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC
ISFPAHLLASQKPEIVRLLADQEAEFDFRLREHGAEIATFELQIAALEAQIAGHTVQQEE
CCCCHHHHCCCCCHHHHHHHCCCCCCCHHHHHCCCEEEEEEEEEEEEHHHHHCCCHHHHH
TARQLELLVEERQALETLLAKGLTRKSQVLALKRNEAELHGRQGQLAAAIAESRRTMAEI
HHHHHHHHHHHHHHHHHHHHHCCCCCHHEEEEECCCHHHCCCCCHHHHHHHHHHHHHHHH
RERIEQVRSARTSKASAQLSELRLKRAEVLEQLRAAEDVSGRLVVRAPASGTVINLAKYN
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEECCCCCEEEEEECC
PGAVIAPGEDLMSIVPEESGLVVEARIRPLDIDEIRVGQEARLNFSAFDARQTPPIETKV
CCEEEECCHHHHHHCCCCCCEEEEEECCCCCHHHHCCCCHHCCCEEEECCCCCCCCCEEE
VYLSADRFESERGEPYYIARLEIPAGSGAGFDPSKIGPGQEAEVFITTGERTFFGYIAAP
EEEECCCCCCCCCCEEEEEEEEECCCCCCCCCCCCCCCCCCCEEEEEECCCHHHHHHHHH
LMKTLSRSVRES
HHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 2184029 [H]