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The map label for this gene is cutL [H]

Identifier: 110632835

GI number: 110632835

Start: 522722

End: 525103

Strand: Reverse

Name: cutL [H]

Synonym: Meso_0474

Alternate gene names: 110632835

Gene position: 525103-522722 (Counterclockwise)

Preceding gene: 110632836

Following gene: 110632834

Centisome position: 11.9

GC content: 58.61

Gene sequence:

>2382_bases
ATGCCTACCTTAGCTGAGCAATCGGCCGTCTCCAGCTCCATTCCTCGCATCGACGCGCATCGTTATGTGAGTGGGAAGCC
GGTTTATACCTCTGATCTACTCCCAGCTGGCTGCCTCCATATGGCTCTGTTGCGCAGTCCGCATCCGCGCGCGCGCATCG
TTAGTCTTGATGTAATGAAGGCAAAGGCAGCGCCCGATATCGTTGAGGTTGTGACCGCAGTAGACCTCGACGATCTAAAG
CCGATCCCTGCGGCACTTCCCTTCAGGAGCGACGTGGAGGGGCGAGGAACGATTGTCGGTCGATGTCTTGCGGATGGCGA
GGTTTGTTACATCGGTCAACCAATCGCTGCTGTCGTCGCAACCAGTGTGCACAGCGCCCAGGCAGCTCTCGACCTGATCG
AAGTCGAGTACCAGCCGTTGCAAGCGGTCCTTGACTTCGACGAAGCACTTGATGCGGGAGCGGTCGCTGCGCACCCCGGT
TGGGCTACGAACGTGGTCGCCCGTGACGAGATCCATCGGGGCGATTTCGAAGCCGCCCTACGTTTGGCAGATGTGGTCGT
TGCCGGGGAGCTTGAGTTCGCGCCGTCAACAGCCGCACCCATGGAACCATGCTGTTTTACGGGAGATTGGGACCCGGCAC
TTGAACGCGTATCCCTGACCGGTACCCTGCAGAACCCTCACACAACCCGCTGGATGATCGCCACGGCGCTCAATATCCAA
GAGACCGCCGTGCGCGTGGTCGCGCCACCGCTTGGCGGCTCATTTGGCTTAAAAATGGCGGGGCATCCTGAAGAGGTTCT
TGTATGCGCCTTGGCGCGGTTTCTTAAGCGGCCGGTCAATTACACGGAAGAACGCTGGGAAACGCTGATGGCTCCTTGCC
GCCGGCAGAAGCATAGGTTCCAGATCGCGGCGACACGCGACGGCAGGATTCTTGGCTTCGAAGACCAGTTTGTCGCAGAT
GTCGGCATCACGGGGCCCGGCAATGGTTGGTCGATGCCGCTCGTTACGGCTACGGTCTTCCCGACGGTCTACGATGTGGA
GCACTGCCGGATCTCCGCGACATTGATCGCGACCAATTCCACGCCTTGGCAACCTATCCGCGGGTATGGCAAGGAGATCG
GTAACACTGTGATGGAGCGGGCCATCGATTTGCTCGCGGCACATCTCAGAATGGACCCGGTGGCCCTGCGGCACCTGAAC
CTGATTGCGGCCGGCGATTTTCCGAAAAAACTTGCCTCCGGTCTCAATCTCGATAGCGGTGACTATCCGACCGCGCTCGA
GAAGCTGACGAAGCTATTTGGCTACGACGCTTGGCGCCATCGGCAATCGAAGCAACGCCAATCGGAAAAGGTTATTGGCA
TTGGCATCGCGTTCGAATTGACGCCTGAAGGAGGAGCTCGACCGGGTGCATTCCCCAGCGGATTTGAAACCGCTACCGTT
AAGCTCCTTCCTGGCGGGAGCGTGCAGGTTCTGGTTGGGGTAACTTCACCCGGGAGCGGCAACGAAACTGGTATTGCCCA
ACTCGTTGCGGCGGAACTGGGCGTCGATGCTAGATCCGTCCAAGTGGTGCAAGGGGATACTGACGTAACGCCTGTTGGTA
CCGGACATGCAAGCAGCCGGGCGATGCTCTATGGTGGTACCGCGGCCGTTCTTGCCGCGCGCGATCTTCGTGCGAAGGTT
TTGTTATGCGCTGCAAACATTCTTCGAGCGCCGACGGAAGGTCTCTCCCTAGAGGCGAGCATGATACGCGACAGTGAGGG
GAATGGTGTCCTAACTCTTCAAGAAGTCTCCCACCAGGCGCATACCAATCCCATCATCGTGGCGAAGGGTACTGAACTGC
CACTTGAAGCTACTCGCAGCTTTCAGCCCATCAATGTCAGCGTTATTCCCGATGAAAAGGGCCGCATCGCGACGTATTCT
TCCTTCCCCTACTCGGTTCACGCAGCCGCCATCGAGCTCGATCGAGAGACTGGTTCGGTCAAGGTCTTGGACTACGCTTG
CGTCCATGATTGCGGTGTGATGATCAACCCAATGCTGGTTACGGGGCAGCTAAAGGGCGCAATTGTCATGGGTATCGGAG
CCGCCCTGTGGGAGGAGCTTGCCTATGATGATCAGAGAAGGCCGCTGGCACGTCGTCTTAAAGAATATCTTCTACCGCGT
GCGATAGATCTGCCTGAAATCCGCGTAGGGCACATGAGTACGCCCAGCCCATATCATCCCCTCGGACTGAAGGGCGCAGG
CGAGTCGGGGGTCGGTGGCGGTATTGCAGCGATGCTTTCCGCCGTCGCTGACGCTTTGGGGGAACGGCGCGCCGCGCTGA
CACGCTGTCCCGCAACACCGCCAACACTTCTGGATATCCTGCATGATACCCAACCGTTTTGA

Upstream 100 bases:

>100_bases
ATGGCTCTTGAGGTGGCGGACCATGTCTACGTCTTGCGGCGGGGTGGAATTGCCCTCAGCAAACCGCGATCCGAGATTGT
AGACACGCAGGAAATCTTCG

Downstream 100 bases:

>100_bases
CTACGCTGCGCCAAAGACGCTGGATGCGGCTCTCGAGCTTCTCTCTGGGCGAAACGATGCCAAAATTCTCGGCGGAGGCA
CAGTGCTGGTGCCACTGATG

Product: xanthine dehydrogenase, molybdenum binding subunit apoprotein

Products: NA

Alternate protein names: CO dehydrogenase subunit L; CO-DH L [H]

Number of amino acids: Translated: 793; Mature: 792

Protein sequence:

>793_residues
MPTLAEQSAVSSSIPRIDAHRYVSGKPVYTSDLLPAGCLHMALLRSPHPRARIVSLDVMKAKAAPDIVEVVTAVDLDDLK
PIPAALPFRSDVEGRGTIVGRCLADGEVCYIGQPIAAVVATSVHSAQAALDLIEVEYQPLQAVLDFDEALDAGAVAAHPG
WATNVVARDEIHRGDFEAALRLADVVVAGELEFAPSTAAPMEPCCFTGDWDPALERVSLTGTLQNPHTTRWMIATALNIQ
ETAVRVVAPPLGGSFGLKMAGHPEEVLVCALARFLKRPVNYTEERWETLMAPCRRQKHRFQIAATRDGRILGFEDQFVAD
VGITGPGNGWSMPLVTATVFPTVYDVEHCRISATLIATNSTPWQPIRGYGKEIGNTVMERAIDLLAAHLRMDPVALRHLN
LIAAGDFPKKLASGLNLDSGDYPTALEKLTKLFGYDAWRHRQSKQRQSEKVIGIGIAFELTPEGGARPGAFPSGFETATV
KLLPGGSVQVLVGVTSPGSGNETGIAQLVAAELGVDARSVQVVQGDTDVTPVGTGHASSRAMLYGGTAAVLAARDLRAKV
LLCAANILRAPTEGLSLEASMIRDSEGNGVLTLQEVSHQAHTNPIIVAKGTELPLEATRSFQPINVSVIPDEKGRIATYS
SFPYSVHAAAIELDRETGSVKVLDYACVHDCGVMINPMLVTGQLKGAIVMGIGAALWEELAYDDQRRPLARRLKEYLLPR
AIDLPEIRVGHMSTPSPYHPLGLKGAGESGVGGGIAAMLSAVADALGERRAALTRCPATPPTLLDILHDTQPF

Sequences:

>Translated_793_residues
MPTLAEQSAVSSSIPRIDAHRYVSGKPVYTSDLLPAGCLHMALLRSPHPRARIVSLDVMKAKAAPDIVEVVTAVDLDDLK
PIPAALPFRSDVEGRGTIVGRCLADGEVCYIGQPIAAVVATSVHSAQAALDLIEVEYQPLQAVLDFDEALDAGAVAAHPG
WATNVVARDEIHRGDFEAALRLADVVVAGELEFAPSTAAPMEPCCFTGDWDPALERVSLTGTLQNPHTTRWMIATALNIQ
ETAVRVVAPPLGGSFGLKMAGHPEEVLVCALARFLKRPVNYTEERWETLMAPCRRQKHRFQIAATRDGRILGFEDQFVAD
VGITGPGNGWSMPLVTATVFPTVYDVEHCRISATLIATNSTPWQPIRGYGKEIGNTVMERAIDLLAAHLRMDPVALRHLN
LIAAGDFPKKLASGLNLDSGDYPTALEKLTKLFGYDAWRHRQSKQRQSEKVIGIGIAFELTPEGGARPGAFPSGFETATV
KLLPGGSVQVLVGVTSPGSGNETGIAQLVAAELGVDARSVQVVQGDTDVTPVGTGHASSRAMLYGGTAAVLAARDLRAKV
LLCAANILRAPTEGLSLEASMIRDSEGNGVLTLQEVSHQAHTNPIIVAKGTELPLEATRSFQPINVSVIPDEKGRIATYS
SFPYSVHAAAIELDRETGSVKVLDYACVHDCGVMINPMLVTGQLKGAIVMGIGAALWEELAYDDQRRPLARRLKEYLLPR
AIDLPEIRVGHMSTPSPYHPLGLKGAGESGVGGGIAAMLSAVADALGERRAALTRCPATPPTLLDILHDTQPF
>Mature_792_residues
PTLAEQSAVSSSIPRIDAHRYVSGKPVYTSDLLPAGCLHMALLRSPHPRARIVSLDVMKAKAAPDIVEVVTAVDLDDLKP
IPAALPFRSDVEGRGTIVGRCLADGEVCYIGQPIAAVVATSVHSAQAALDLIEVEYQPLQAVLDFDEALDAGAVAAHPGW
ATNVVARDEIHRGDFEAALRLADVVVAGELEFAPSTAAPMEPCCFTGDWDPALERVSLTGTLQNPHTTRWMIATALNIQE
TAVRVVAPPLGGSFGLKMAGHPEEVLVCALARFLKRPVNYTEERWETLMAPCRRQKHRFQIAATRDGRILGFEDQFVADV
GITGPGNGWSMPLVTATVFPTVYDVEHCRISATLIATNSTPWQPIRGYGKEIGNTVMERAIDLLAAHLRMDPVALRHLNL
IAAGDFPKKLASGLNLDSGDYPTALEKLTKLFGYDAWRHRQSKQRQSEKVIGIGIAFELTPEGGARPGAFPSGFETATVK
LLPGGSVQVLVGVTSPGSGNETGIAQLVAAELGVDARSVQVVQGDTDVTPVGTGHASSRAMLYGGTAAVLAARDLRAKVL
LCAANILRAPTEGLSLEASMIRDSEGNGVLTLQEVSHQAHTNPIIVAKGTELPLEATRSFQPINVSVIPDEKGRIATYSS
FPYSVHAAAIELDRETGSVKVLDYACVHDCGVMINPMLVTGQLKGAIVMGIGAALWEELAYDDQRRPLARRLKEYLLPRA
IDLPEIRVGHMSTPSPYHPLGLKGAGESGVGGGIAAMLSAVADALGERRAALTRCPATPPTLLDILHDTQPF

Specific function: Catalyzes the oxidation of carbon monoxide to carbon dioxide [H]

COG id: COG1529

COG function: function code C; Aerobic-type carbon monoxide dehydrogenase, large subunit CoxL/CutL homologs

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

Organism=Homo sapiens, GI91823271, Length=794, Percent_Identity=22.6700251889169, Blast_Score=121, Evalue=3e-27,
Organism=Homo sapiens, GI71773480, Length=806, Percent_Identity=22.3325062034739, Blast_Score=115, Evalue=1e-25,
Organism=Escherichia coli, GI1789246, Length=831, Percent_Identity=27.9181708784597, Blast_Score=235, Evalue=7e-63,
Organism=Escherichia coli, GI1789230, Length=792, Percent_Identity=27.9040404040404, Blast_Score=216, Evalue=4e-57,
Organism=Escherichia coli, GI1786478, Length=773, Percent_Identity=26.1319534282018, Blast_Score=112, Evalue=6e-26,
Organism=Caenorhabditis elegans, GI17539860, Length=783, Percent_Identity=21.3282247765006, Blast_Score=119, Evalue=5e-27,
Organism=Caenorhabditis elegans, GI17540638, Length=735, Percent_Identity=23.5374149659864, Blast_Score=112, Evalue=1e-24,
Organism=Caenorhabditis elegans, GI32566215, Length=582, Percent_Identity=22.5085910652921, Blast_Score=90, Evalue=4e-18,
Organism=Drosophila melanogaster, GI17737937, Length=772, Percent_Identity=24.0932642487047, Blast_Score=128, Evalue=1e-29,
Organism=Drosophila melanogaster, GI24647199, Length=751, Percent_Identity=23.1691078561917, Blast_Score=112, Evalue=1e-24,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000674
- InterPro:   IPR008274
- InterPro:   IPR012780 [H]

Pfam domain/function: PF01315 Ald_Xan_dh_C; PF02738 Ald_Xan_dh_C2 [H]

EC number: =1.2.99.2 [H]

Molecular weight: Translated: 84559; Mature: 84428

Theoretical pI: Translated: 5.98; Mature: 5.98

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
3.7 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
3.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPTLAEQSAVSSSIPRIDAHRYVSGKPVYTSDLLPAGCLHMALLRSPHPRARIVSLDVMK
CCCCCHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHCCCCCCEEEEEEEEHH
AKAAPDIVEVVTAVDLDDLKPIPAALPFRSDVEGRGTIVGRCLADGEVCYIGQPIAAVVA
HCCCCHHHHHHHHCCHHCCCCCCCCCCCCCCCCCCCEEEEEEECCCCEEEECCCHHHHHH
TSVHSAQAALDLIEVEYQPLQAVLDFDEALDAGAVAAHPGWATNVVARDEIHRGDFEAAL
HHHHHHHHHHHHHHHCHHHHHHHHHHHHHHCCCCEECCCCCCCCEEECCCCCCCCHHHHH
RLADVVVAGELEFAPSTAAPMEPCCFTGDWDPALERVSLTGTLQNPHTTRWMIATALNIQ
HHHHEEEECCEEECCCCCCCCCCCEECCCCCHHHHEEEEEEECCCCCCCEEEEEEECCHH
ETAVRVVAPPLGGSFGLKMAGHPEEVLVCALARFLKRPVNYTEERWETLMAPCRRQKHRF
HHEEEEEECCCCCCCCCEECCCHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHCCCCEE
QIAATRDGRILGFEDQFVADVGITGPGNGWSMPLVTATVFPTVYDVEHCRISATLIATNS
EEEEECCCEEECCCCCEEEEECCCCCCCCCCCCEEHHHHCCHHEECCCEEEEEEEEEECC
TPWQPIRGYGKEIGNTVMERAIDLLAAHLRMDPVALRHLNLIAAGDFPKKLASGLNLDSG
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHEEEEEECCCHHHHHCCCCCCCC
DYPTALEKLTKLFGYDAWRHRQSKQRQSEKVIGIGIAFELTPEGGARPGAFPSGFETATV
CCCHHHHHHHHHHCCHHHHHHHHHHHHCCCEEEEEEEEEECCCCCCCCCCCCCCCCEEEE
KLLPGGSVQVLVGVTSPGSGNETGIAQLVAAELGVDARSVQVVQGDTDVTPVGTGHASSR
EEECCCCEEEEEEECCCCCCCCHHHHHHHHHHHCCCCCEEEEEECCCCCCCCCCCCCCCC
AMLYGGTAAVLAARDLRAKVLLCAANILRAPTEGLSLEASMIRDSEGNGVLTLQEVSHQA
EEEECCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEHHHEECCCCCCEEEHHHHHHHH
HTNPIIVAKGTELPLEATRSFQPINVSVIPDEKGRIATYSSFPYSVHAAAIELDRETGSV
CCCCEEEECCCCCCHHHHCCCCCEEEEEECCCCCCEEEEECCCCEEEEEEEEEECCCCCE
KVLDYACVHDCGVMINPMLVTGQLKGAIVMGIGAALWEELAYDDQRRPLARRLKEYLLPR
EEEEEHHHHHCCCEECCEEEEECCCCEEEEHHHHHHHHHHHCCCCCCHHHHHHHHHHCCC
AIDLPEIRVGHMSTPSPYHPLGLKGAGESGVGGGIAAMLSAVADALGERRAALTRCPATP
CCCCCCEEECCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCC
PTLLDILHDTQPF
HHHHHHHHCCCCC
>Mature Secondary Structure 
PTLAEQSAVSSSIPRIDAHRYVSGKPVYTSDLLPAGCLHMALLRSPHPRARIVSLDVMK
CCCCHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHCCCCCCEEEEEEEEHH
AKAAPDIVEVVTAVDLDDLKPIPAALPFRSDVEGRGTIVGRCLADGEVCYIGQPIAAVVA
HCCCCHHHHHHHHCCHHCCCCCCCCCCCCCCCCCCCEEEEEEECCCCEEEECCCHHHHHH
TSVHSAQAALDLIEVEYQPLQAVLDFDEALDAGAVAAHPGWATNVVARDEIHRGDFEAAL
HHHHHHHHHHHHHHHCHHHHHHHHHHHHHHCCCCEECCCCCCCCEEECCCCCCCCHHHHH
RLADVVVAGELEFAPSTAAPMEPCCFTGDWDPALERVSLTGTLQNPHTTRWMIATALNIQ
HHHHEEEECCEEECCCCCCCCCCCEECCCCCHHHHEEEEEEECCCCCCCEEEEEEECCHH
ETAVRVVAPPLGGSFGLKMAGHPEEVLVCALARFLKRPVNYTEERWETLMAPCRRQKHRF
HHEEEEEECCCCCCCCCEECCCHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHCCCCEE
QIAATRDGRILGFEDQFVADVGITGPGNGWSMPLVTATVFPTVYDVEHCRISATLIATNS
EEEEECCCEEECCCCCEEEEECCCCCCCCCCCCEEHHHHCCHHEECCCEEEEEEEEEECC
TPWQPIRGYGKEIGNTVMERAIDLLAAHLRMDPVALRHLNLIAAGDFPKKLASGLNLDSG
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHEEEEEECCCHHHHHCCCCCCCC
DYPTALEKLTKLFGYDAWRHRQSKQRQSEKVIGIGIAFELTPEGGARPGAFPSGFETATV
CCCHHHHHHHHHHCCHHHHHHHHHHHHCCCEEEEEEEEEECCCCCCCCCCCCCCCCEEEE
KLLPGGSVQVLVGVTSPGSGNETGIAQLVAAELGVDARSVQVVQGDTDVTPVGTGHASSR
EEECCCCEEEEEEECCCCCCCCHHHHHHHHHHHCCCCCEEEEEECCCCCCCCCCCCCCCC
AMLYGGTAAVLAARDLRAKVLLCAANILRAPTEGLSLEASMIRDSEGNGVLTLQEVSHQA
EEEECCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEHHHEECCCCCCEEEHHHHHHHH
HTNPIIVAKGTELPLEATRSFQPINVSVIPDEKGRIATYSSFPYSVHAAAIELDRETGSV
CCCCEEEECCCCCCHHHHCCCCCEEEEEECCCCCCEEEEECCCCEEEEEEEEEECCCCCE
KVLDYACVHDCGVMINPMLVTGQLKGAIVMGIGAALWEELAYDDQRRPLARRLKEYLLPR
EEEEEHHHHHCCCEECCEEEEECCCCEEEEHHHHHHHHHHHCCCCCCHHHHHHHHHHCCC
AIDLPEIRVGHMSTPSPYHPLGLKGAGESGVGGGIAAMLSAVADALGERRAALTRCPATP
CCCCCCEEECCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCC
PTLLDILHDTQPF
HHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 10482497; 2818128; 10966817; 11076018 [H]