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The map label for this gene is yscR [H]

Identifier: 110632472

GI number: 110632472

Start: 138551

End: 139213

Strand: Direct

Name: yscR [H]

Synonym: Meso_0110

Alternate gene names: 110632472

Gene position: 138551-139213 (Clockwise)

Preceding gene: 110632471

Following gene: 110632473

Centisome position: 3.14

GC content: 52.94

Gene sequence:

>663_bases
ATGACGGCGGTTGAGAACTTCCCGGCTATTCTGCCGACCATCATCGCTGTAATGGCGCTGAGCTTCATTCCGTTTATCGT
GGTAATGGGCACGGCGTTCACAAAGATATCCATCGTGTTGATGCTGTTGCGCAATGCAATCGGCGTGCAACAGGCCCCTT
CGGGGCTGGTGATCAACTCCATCGCCTTGACGCTGACGGTGTTCGTGATGGTCCCGGTCGGGAATGCCATCATCACCCAG
GTGCAGCAGCAGCAATTGGGCTTTACTGGCTGGGAAAATGTCTCCCAGCTGTATTCTGTCGTTTCTGAGGCGTTTACCGG
TTACCTAAAGCAGTTTTCCTCTCCGCGTGAACTCCAGTTTTTCATGGATGCGGCCAGGAAGATGTGGCCTGAAACACTGC
ATGGGCAAATTACAACCGACAACGTTTTCATCCTTTTACCCGCACATGTGACATCGGAACTTACAAGGGCTTTTCAGATC
GCCTTTCTCATTTTCCTGCCCTTTGTTGTGGTCGATATGGTGGTTTCCAATATCTTGCTGGCCATGGGGGCGATGATGGT
GCCGCCCATGCTGGTGTCTCTGCCCATCAAGATACTGTTGTTTGTCGCCGCCGACGGCTGGGCTCTTCTGCTCCACAATC
TCGTATTGAGCTACGCGCGATGA

Upstream 100 bases:

>100_bases
ACCATTCTTGCCAATGGCGCACCAGCCGGCCGGGGCTATCTCGTGCAGATCGGCGATCATATGGGCGTGCAGCTTAGTCA
TTGGGCAGGCACGAAGCACA

Downstream 100 bases:

>100_bases
TGCGTCCTCTCATCTGGGAGAACCACAGGAGGATGCACATTGTCGCCAGATGACGTGATGATGATGGCGCGCAACGCCAT
TGTCCTGGTCTTTTATCTGT

Product: type III secretion system protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 220; Mature: 219

Protein sequence:

>220_residues
MTAVENFPAILPTIIAVMALSFIPFIVVMGTAFTKISIVLMLLRNAIGVQQAPSGLVINSIALTLTVFVMVPVGNAIITQ
VQQQQLGFTGWENVSQLYSVVSEAFTGYLKQFSSPRELQFFMDAARKMWPETLHGQITTDNVFILLPAHVTSELTRAFQI
AFLIFLPFVVVDMVVSNILLAMGAMMVPPMLVSLPIKILLFVAADGWALLLHNLVLSYAR

Sequences:

>Translated_220_residues
MTAVENFPAILPTIIAVMALSFIPFIVVMGTAFTKISIVLMLLRNAIGVQQAPSGLVINSIALTLTVFVMVPVGNAIITQ
VQQQQLGFTGWENVSQLYSVVSEAFTGYLKQFSSPRELQFFMDAARKMWPETLHGQITTDNVFILLPAHVTSELTRAFQI
AFLIFLPFVVVDMVVSNILLAMGAMMVPPMLVSLPIKILLFVAADGWALLLHNLVLSYAR
>Mature_219_residues
TAVENFPAILPTIIAVMALSFIPFIVVMGTAFTKISIVLMLLRNAIGVQQAPSGLVINSIALTLTVFVMVPVGNAIITQV
QQQQLGFTGWENVSQLYSVVSEAFTGYLKQFSSPRELQFFMDAARKMWPETLHGQITTDNVFILLPAHVTSELTRAFQIA
FLIFLPFVVVDMVVSNILLAMGAMMVPPMLVSLPIKILLFVAADGWALLLHNLVLSYAR

Specific function: Component of the yop secretion machinery. May have a role in the negative pathway regulation of yop expression controlled by calcium [H]

COG id: COG4790

COG function: function code U; Type III secretory pathway, component EscR

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the fliP/mopC/spaP family [H]

Homologues:

Organism=Escherichia coli, GI1788259, Length=216, Percent_Identity=38.4259259259259, Blast_Score=129, Evalue=2e-31,

Paralogues:

None

Copy number: 10-20 (rich media) [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005838
- InterPro:   IPR005773 [H]

Pfam domain/function: PF00813 FliP [H]

EC number: NA

Molecular weight: Translated: 24171; Mature: 24040

Theoretical pI: Translated: 6.80; Mature: 6.80

Prosite motif: PS01061 FLIP_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
5.5 %Met     (Translated Protein)
5.5 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
5.0 %Met     (Mature Protein)
5.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTAVENFPAILPTIIAVMALSFIPFIVVMGTAFTKISIVLMLLRNAIGVQQAPSGLVINS
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHH
IALTLTVFVMVPVGNAIITQVQQQQLGFTGWENVSQLYSVVSEAFTGYLKQFSSPRELQF
HHHHHHHHHHHHCCHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCHHHHH
FMDAARKMWPETLHGQITTDNVFILLPAHVTSELTRAFQIAFLIFLPFVVVDMVVSNILL
HHHHHHHHCHHHHCCEEEECCEEEEECHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
AMGAMMVPPMLVSLPIKILLFVAADGWALLLHNLVLSYAR
HHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHCC
>Mature Secondary Structure 
TAVENFPAILPTIIAVMALSFIPFIVVMGTAFTKISIVLMLLRNAIGVQQAPSGLVINS
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHH
IALTLTVFVMVPVGNAIITQVQQQQLGFTGWENVSQLYSVVSEAFTGYLKQFSSPRELQF
HHHHHHHHHHHHCCHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCHHHHH
FMDAARKMWPETLHGQITTDNVFILLPAHVTSELTRAFQIAFLIFLPFVVVDMVVSNILL
HHHHHHHHCHHHHCCEEEECCEEEEECHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
AMGAMMVPPMLVSLPIKILLFVAADGWALLLHNLVLSYAR
HHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 8300512; 9746557; 9748454; 11586360 [H]