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The map label for this gene is yscN [H]

Identifier: 110632469

GI number: 110632469

Start: 135736

End: 137025

Strand: Direct

Name: yscN [H]

Synonym: Meso_0107

Alternate gene names: 110632469

Gene position: 135736-137025 (Clockwise)

Preceding gene: 110632468

Following gene: 110632470

Centisome position: 3.08

GC content: 61.63

Gene sequence:

>1290_bases
ATGACGCGGGAACCCGAATTGAAGCGGCCGTTCAGGCGCCGCGGGCGGGTCAGTAAGGCCGTGGGGCCTGTGGTGCGGGC
GGCGGGCAATTTCTGCGTGGGGGAAATCTGCGCGGTTTCGCGCAGCAATGGCGATCCAATCCTGGCTGAGGTGGTCGGCT
TCGATCAGGGGGAAGCCATCCTGACTCCATACGGAGGCACGGCCGGCATATCGCACAACTCCACGATTGAGCCGCTGATG
AGTACATTTGAAGTGCCGGTTGGCGAGGAACTGACGGGACGGGTGATCGATGCGATGGGCAAGCCGATAGATGCCGGCCC
GAGCGTGACATCATGCGCGTTCTATCCCGGCCATCGGACGGCTCCCAATCCGATGCTGCGACCGACTATCGACCGCCCCT
TCATTCTTGGAGTGAGGGTTTTGGATGGTGCCCTGACATGTGGCGAGGGGCAGCGCATGGGCATTTTTGCCGCCGCCGGC
GGGGGAAAATCGACGCTGGTTTCCCTAATGGTGCGTTTCGCCGAATACGACCGCTGCGTAATTGCGCTGATTGGCGAGCG
TGGTCGCGAAGTGCGCGAATTCCTCGAACATCAGCTGGGGCCGACAGGTCTTGCCAAATCCATTGTCGTGGTGGCCACAT
CGGATCGCCCTGCGATCGAGCAGGTGAAGGCGGCCTACACGGCCACGGCACTCGCTGAATTCCACCGCGACAGAGGCGAG
CGGGTGCTGCTGATCATGGACAGCTTAACCCGTTTTGCCCGCGCGCAACGGCAGATAGGCCTGGCGGCAGGGGAGCCTCC
GACCCGGCGCGGCTTTCCTCCGTCCGTCTTCGAGCTGCTTCCGGGTCTTGTTGAGCGCGCGGGCCTCAGCGGCGATGGCT
CGATCACCGCTTTCTACACGGTTTTGGTGGAAGGCGACGATATGAACGAGCCCGTTGCCGATGAGGTGCGCTCGCTTCTC
GACGGCCATATCGTCCTTTCGCGGAAATTGGCAGAAGCGGGTCACTATCCTCCGGTCGATGTCATTACCAGCACCAGCCG
TATCCTGAGCCGCATCGTTTCTCCGGACCATCTGGAAGCCGTTCACAAGGCGCGCGGGCTCATGTCGAAACTCCAGGAAA
TAGAGCTGCTGCTAAAGATCGGCGAGTATTCGAAGGGTGCCGATGCACTGGCCGATGAGGCCCTGGCCCGCAGGACGGCG
CTGGATGCGTTTCTGCGCCAGGGCGTAAACGAGTTTTCAAGCTTCGAGGAAACCGTTATTGCTCTGAAGCGGGCAGTTGG
CCATGCTTGA

Upstream 100 bases:

>100_bases
GTCCTGACGTTATCGATTTAAGCCTCACCGTCGTGGTGGAGGAGATGATCGCGGCGCTTCATATCGCGGGGGCCGTCGTT
AGAACCGGCGGTGAAAACTG

Downstream 100 bases:

>100_bases
TTTTTCGCGGATCGTCGCGCTCCGCCAGCTCCGGCTTGACCGCATGCTCAAAGCAGAAAACGCGGAACAGGCCGCCGCTT
CGGAGGCGCTGTCGTCTTTG

Product: FliI/YscN family ATPase

Products: NA

Alternate protein names: Yop proteins secretion ATPase [H]

Number of amino acids: Translated: 429; Mature: 428

Protein sequence:

>429_residues
MTREPELKRPFRRRGRVSKAVGPVVRAAGNFCVGEICAVSRSNGDPILAEVVGFDQGEAILTPYGGTAGISHNSTIEPLM
STFEVPVGEELTGRVIDAMGKPIDAGPSVTSCAFYPGHRTAPNPMLRPTIDRPFILGVRVLDGALTCGEGQRMGIFAAAG
GGKSTLVSLMVRFAEYDRCVIALIGERGREVREFLEHQLGPTGLAKSIVVVATSDRPAIEQVKAAYTATALAEFHRDRGE
RVLLIMDSLTRFARAQRQIGLAAGEPPTRRGFPPSVFELLPGLVERAGLSGDGSITAFYTVLVEGDDMNEPVADEVRSLL
DGHIVLSRKLAEAGHYPPVDVITSTSRILSRIVSPDHLEAVHKARGLMSKLQEIELLLKIGEYSKGADALADEALARRTA
LDAFLRQGVNEFSSFEETVIALKRAVGHA

Sequences:

>Translated_429_residues
MTREPELKRPFRRRGRVSKAVGPVVRAAGNFCVGEICAVSRSNGDPILAEVVGFDQGEAILTPYGGTAGISHNSTIEPLM
STFEVPVGEELTGRVIDAMGKPIDAGPSVTSCAFYPGHRTAPNPMLRPTIDRPFILGVRVLDGALTCGEGQRMGIFAAAG
GGKSTLVSLMVRFAEYDRCVIALIGERGREVREFLEHQLGPTGLAKSIVVVATSDRPAIEQVKAAYTATALAEFHRDRGE
RVLLIMDSLTRFARAQRQIGLAAGEPPTRRGFPPSVFELLPGLVERAGLSGDGSITAFYTVLVEGDDMNEPVADEVRSLL
DGHIVLSRKLAEAGHYPPVDVITSTSRILSRIVSPDHLEAVHKARGLMSKLQEIELLLKIGEYSKGADALADEALARRTA
LDAFLRQGVNEFSSFEETVIALKRAVGHA
>Mature_428_residues
TREPELKRPFRRRGRVSKAVGPVVRAAGNFCVGEICAVSRSNGDPILAEVVGFDQGEAILTPYGGTAGISHNSTIEPLMS
TFEVPVGEELTGRVIDAMGKPIDAGPSVTSCAFYPGHRTAPNPMLRPTIDRPFILGVRVLDGALTCGEGQRMGIFAAAGG
GKSTLVSLMVRFAEYDRCVIALIGERGREVREFLEHQLGPTGLAKSIVVVATSDRPAIEQVKAAYTATALAEFHRDRGER
VLLIMDSLTRFARAQRQIGLAAGEPPTRRGFPPSVFELLPGLVERAGLSGDGSITAFYTVLVEGDDMNEPVADEVRSLLD
GHIVLSRKLAEAGHYPPVDVITSTSRILSRIVSPDHLEAVHKARGLMSKLQEIELLLKIGEYSKGADALADEALARRTAL
DAFLRQGVNEFSSFEETVIALKRAVGHA

Specific function: Is a component of the Yop secretion machinery using ATP, and it is either the energizer of this machinery, or part of it [H]

COG id: COG1157

COG function: function code NU; Flagellar biosynthesis/type III secretory pathway ATPase

Gene ontology:

Cell location: Cytoplasm. Note=But connected to the inner membrane possibly through LcrD (Probable) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ATPase alpha/beta chains family [H]

Homologues:

Organism=Homo sapiens, GI32189394, Length=357, Percent_Identity=30.2521008403361, Blast_Score=144, Evalue=2e-34,
Organism=Homo sapiens, GI50345984, Length=371, Percent_Identity=27.7628032345013, Blast_Score=134, Evalue=1e-31,
Organism=Homo sapiens, GI4757810, Length=371, Percent_Identity=27.7628032345013, Blast_Score=134, Evalue=1e-31,
Organism=Homo sapiens, GI19913428, Length=413, Percent_Identity=25.181598062954, Blast_Score=122, Evalue=8e-28,
Organism=Homo sapiens, GI19913426, Length=401, Percent_Identity=25.6857855361596, Blast_Score=117, Evalue=3e-26,
Organism=Homo sapiens, GI19913424, Length=339, Percent_Identity=28.023598820059, Blast_Score=100, Evalue=2e-21,
Organism=Escherichia coli, GI1788251, Length=428, Percent_Identity=45.3271028037383, Blast_Score=337, Evalue=1e-93,
Organism=Escherichia coli, GI1790170, Length=350, Percent_Identity=28.5714285714286, Blast_Score=145, Evalue=5e-36,
Organism=Escherichia coli, GI1790172, Length=313, Percent_Identity=32.5878594249201, Blast_Score=135, Evalue=6e-33,
Organism=Escherichia coli, GI1790217, Length=248, Percent_Identity=29.0322580645161, Blast_Score=74, Evalue=3e-14,
Organism=Caenorhabditis elegans, GI25144756, Length=379, Percent_Identity=28.7598944591029, Blast_Score=136, Evalue=2e-32,
Organism=Caenorhabditis elegans, GI71988080, Length=371, Percent_Identity=27.4932614555256, Blast_Score=130, Evalue=2e-30,
Organism=Caenorhabditis elegans, GI71988063, Length=371, Percent_Identity=27.4932614555256, Blast_Score=129, Evalue=2e-30,
Organism=Caenorhabditis elegans, GI17570191, Length=332, Percent_Identity=28.0120481927711, Blast_Score=122, Evalue=4e-28,
Organism=Caenorhabditis elegans, GI17510931, Length=341, Percent_Identity=27.2727272727273, Blast_Score=119, Evalue=4e-27,
Organism=Caenorhabditis elegans, GI17565854, Length=323, Percent_Identity=29.4117647058824, Blast_Score=112, Evalue=4e-25,
Organism=Caenorhabditis elegans, GI71988074, Length=336, Percent_Identity=26.7857142857143, Blast_Score=108, Evalue=5e-24,
Organism=Saccharomyces cerevisiae, GI6319370, Length=377, Percent_Identity=27.3209549071618, Blast_Score=133, Evalue=6e-32,
Organism=Saccharomyces cerevisiae, GI6319603, Length=406, Percent_Identity=27.0935960591133, Blast_Score=128, Evalue=2e-30,
Organism=Saccharomyces cerevisiae, GI6322581, Length=356, Percent_Identity=29.2134831460674, Blast_Score=127, Evalue=4e-30,
Organism=Saccharomyces cerevisiae, GI6320016, Length=274, Percent_Identity=27.007299270073, Blast_Score=86, Evalue=1e-17,
Organism=Drosophila melanogaster, GI24658560, Length=360, Percent_Identity=28.3333333333333, Blast_Score=135, Evalue=5e-32,
Organism=Drosophila melanogaster, GI24638766, Length=356, Percent_Identity=29.4943820224719, Blast_Score=134, Evalue=2e-31,
Organism=Drosophila melanogaster, GI28574560, Length=417, Percent_Identity=28.2973621103118, Blast_Score=125, Evalue=8e-29,
Organism=Drosophila melanogaster, GI281361666, Length=340, Percent_Identity=28.5294117647059, Blast_Score=119, Evalue=3e-27,
Organism=Drosophila melanogaster, GI24646341, Length=340, Percent_Identity=28.5294117647059, Blast_Score=119, Evalue=3e-27,
Organism=Drosophila melanogaster, GI17136796, Length=340, Percent_Identity=28.5294117647059, Blast_Score=119, Evalue=3e-27,
Organism=Drosophila melanogaster, GI20129479, Length=330, Percent_Identity=27.5757575757576, Blast_Score=107, Evalue=1e-23,
Organism=Drosophila melanogaster, GI24583988, Length=308, Percent_Identity=28.8961038961039, Blast_Score=104, Evalue=1e-22,
Organism=Drosophila melanogaster, GI24583986, Length=308, Percent_Identity=28.8961038961039, Blast_Score=104, Evalue=1e-22,
Organism=Drosophila melanogaster, GI24583984, Length=308, Percent_Identity=28.8961038961039, Blast_Score=104, Evalue=1e-22,
Organism=Drosophila melanogaster, GI24583992, Length=319, Percent_Identity=28.5266457680251, Blast_Score=102, Evalue=4e-22,

Paralogues:

None

Copy number: 10-20 (rich media) [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR020003
- InterPro:   IPR000194
- InterPro:   IPR003593
- InterPro:   IPR004100
- InterPro:   IPR005714
- InterPro:   IPR013380 [H]

Pfam domain/function: PF00006 ATP-synt_ab; PF02874 ATP-synt_ab_N [H]

EC number: =3.6.3.14 [H]

Molecular weight: Translated: 46103; Mature: 45971

Theoretical pI: Translated: 6.80; Mature: 6.80

Prosite motif: PS00152 ATPASE_ALPHA_BETA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTREPELKRPFRRRGRVSKAVGPVVRAAGNFCVGEICAVSRSNGDPILAEVVGFDQGEAI
CCCCCCHHHHHHHCCCHHHHHHHHHHHCCCCHHHHHHHHCCCCCCCHHHHHHCCCCCCEE
LTPYGGTAGISHNSTIEPLMSTFEVPVGEELTGRVIDAMGKPIDAGPSVTSCAFYPGHRT
EECCCCCCCCCCCCHHHHHHHHHCCCCCCHHHHHHHHHCCCCCCCCCCCCEEEECCCCCC
APNPMLRPTIDRPFILGVRVLDGALTCGEGQRMGIFAAAGGGKSTLVSLMVRFAEYDRCV
CCCCCCCCCCCCCCEEHHHHHCCCEECCCCCCEEEEEECCCCHHHHHHHHHHHHHHCHHH
IALIGERGREVREFLEHQLGPTGLAKSIVVVATSDRPAIEQVKAAYTATALAEFHRDRGE
HHHHHHCCHHHHHHHHHCCCCCCCCCCEEEEEECCCHHHHHHHHHHHHHHHHHHHHCCCC
RVLLIMDSLTRFARAQRQIGLAAGEPPTRRGFPPSVFELLPGLVERAGLSGDGSITAFYT
EEEEEHHHHHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHHHHCCCCCCCCEEEEEE
VLVEGDDMNEPVADEVRSLLDGHIVLSRKLAEAGHYPPVDVITSTSRILSRIVSPDHLEA
EEEECCCCCCCHHHHHHHHHCCHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHCCCHHHHH
VHKARGLMSKLQEIELLLKIGEYSKGADALADEALARRTALDAFLRQGVNEFSSFEETVI
HHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
ALKRAVGHA
HHHHHHCCC
>Mature Secondary Structure 
TREPELKRPFRRRGRVSKAVGPVVRAAGNFCVGEICAVSRSNGDPILAEVVGFDQGEAI
CCCCCHHHHHHHCCCHHHHHHHHHHHCCCCHHHHHHHHCCCCCCCHHHHHHCCCCCCEE
LTPYGGTAGISHNSTIEPLMSTFEVPVGEELTGRVIDAMGKPIDAGPSVTSCAFYPGHRT
EECCCCCCCCCCCCHHHHHHHHHCCCCCCHHHHHHHHHCCCCCCCCCCCCEEEECCCCCC
APNPMLRPTIDRPFILGVRVLDGALTCGEGQRMGIFAAAGGGKSTLVSLMVRFAEYDRCV
CCCCCCCCCCCCCCEEHHHHHCCCEECCCCCCEEEEEECCCCHHHHHHHHHHHHHHCHHH
IALIGERGREVREFLEHQLGPTGLAKSIVVVATSDRPAIEQVKAAYTATALAEFHRDRGE
HHHHHHCCHHHHHHHHHCCCCCCCCCCEEEEEECCCHHHHHHHHHHHHHHHHHHHHCCCC
RVLLIMDSLTRFARAQRQIGLAAGEPPTRRGFPPSVFELLPGLVERAGLSGDGSITAFYT
EEEEEHHHHHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHHHHCCCCCCCCEEEEEE
VLVEGDDMNEPVADEVRSLLDGHIVLSRKLAEAGHYPPVDVITSTSRILSRIVSPDHLEA
EEEECCCCCCCHHHHHHHHHCCHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHCCCHHHHH
VHKARGLMSKLQEIELLLKIGEYSKGADALADEALARRTALDAFLRQGVNEFSSFEETVI
HHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
ALKRAVGHA
HHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 8132449; 2160939 [H]