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The map label for this gene is mocR [H]

Identifier: 110632433

GI number: 110632433

Start: 97095

End: 98585

Strand: Direct

Name: mocR [H]

Synonym: Meso_0071

Alternate gene names: 110632433

Gene position: 97095-98585 (Clockwise)

Preceding gene: 110632431

Following gene: 110632435

Centisome position: 2.2

GC content: 64.05

Gene sequence:

>1491_bases
ATGCCGACCAGAAACGATGCCGCTCTTTGGGCGGGCCTAATAAAGATTTCCAGTGATTCCACGCAGACATTGCAGGCGCA
GATTCGCCAGGCGATCGTCTCGGCGATTCTCGACCGGCAAATTTCGCCCACCATGCCGTTGCCGTCCTGCCGCATTCTGG
CCGACAAGCTGGGTGTGGCGCGCGGAACGGTGGTGCTCGCCTTCCAGCAGCTCGTTGATCAGGGTTTTCTCATCGCCCGG
GAGCGGCGCGGCCATTTCGTCAATCCGGAAGTGCTCGCCGCTCCGCCACGTCCGCCGCGCAAGACCCGCACTACGGCAAA
GATCGACTGGAAGGCGCGCCGCCAGGTAATGGCGAGCGAGCTCCCTGGTCCGCCGAAGAACGAGAACTGGATGCAGTCCT
CCTATCCCTTCGTCTACGGGCAGTTCGATCCCACACTGTTCCCCACCGCCGAGTGGCGCGAGTGCAACCGCATGGCGCTC
GCGGTGCTCGAGATCCGCAACTGGGCGGCCGACATGGTCGATAGGGATGACCCGCTGCTGATCGAGCAAATCCAGGCGCG
GCTTCTGCCGCGCCGCGGTATCTTCGCGAATCCGGATGAGATCATCGTGACGCTTGGCGCGCAGCACGCGCTCTACATGC
TTGCCACGCTGCTCATGGGCCGCGGCGCTCGTGTGGCGATGGAAAATCCCGGCTATCCGGACGCCCGCTCCATCTTCCGG
TTGTCTGGTGCCGAGACGCTGTCGGTTCCCGTGGACAAAGACGGCATGGAGGTGGATGCGATCCCGGCGGACTCTAGTTT
CGTTTTCGTTACCCCCAGCCACCATTGCCCGACCATGGTCCCGCTCAGCCGCGAGCGTCGGCAGGCGCTCCTGTCCGGCG
CTGAGAAGAACGACTGGATCATCATTGAGGACGATTACGACAGCCAGCTCGCGGACGAGACGCCCCAAGCGGCGCTGAAA
GGGCTCGACCATACCGGCCGTGTCATTTATCTCGGCTCCATGTCGAAGACGCTGGCGCCGGGTCTGCGGCTTGGCTATCT
CGTCGGGCCGGCCGAACTGGTGGCTGAATTGAGGGCGCTTCGCCGCTTCATGCTGCGTCATCCGCCGGCCAACAATCAGC
GGGCGGTGGCGCTTTTCCTCTCGCTCGGTCATCACGATTCGCTAATAAGGCGGCTCTCCGCCGCCTTCGAGGAGCGTCGC
AGCAAGCTGGTCGAAGTGATCGGCCGTTTAATGCCCGAATGGGAAGCGGCGGATGTGCCCGGTGGCACGTCCATTTGGCT
CCAGGGGCCTGAGGGGATCGACACGGGCGCGCTTTCACGCGCTGCCAGGGCGCGCGGCGTGATTATCGAACCGGGAGCCC
GCTTCTTCGATGGGCCTGAGCGCCCTTCGCGCCATATGCGGCTTGGTATTTCATCCATCGCGGTTCAGCATATCGAGCCG
GGCATCCGCGAGCTTGCCGCTGTCGTCTCCCGCCGCGCCATCGCGGCATAG

Upstream 100 bases:

>100_bases
GCCGAACGGCAAAAGTGAAGCAGCCCTCTGGCTTAATCGCTTGGACCAGGGTTGCGGTGCAGCCGCCATCATCGTAGGCT
CCCCATCGCCGGAGGACATG

Downstream 100 bases:

>100_bases
AGGCGCCGCCAGCGGCAAGGCCCGTGCCTCTTAGGGTGTTCCGTGAAAGGGCCTAATTCAGCAATACGCTGTTGCCGGGA
AAATCGAGCGAGAAGGCAGG

Product: GntR family transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 496; Mature: 495

Protein sequence:

>496_residues
MPTRNDAALWAGLIKISSDSTQTLQAQIRQAIVSAILDRQISPTMPLPSCRILADKLGVARGTVVLAFQQLVDQGFLIAR
ERRGHFVNPEVLAAPPRPPRKTRTTAKIDWKARRQVMASELPGPPKNENWMQSSYPFVYGQFDPTLFPTAEWRECNRMAL
AVLEIRNWAADMVDRDDPLLIEQIQARLLPRRGIFANPDEIIVTLGAQHALYMLATLLMGRGARVAMENPGYPDARSIFR
LSGAETLSVPVDKDGMEVDAIPADSSFVFVTPSHHCPTMVPLSRERRQALLSGAEKNDWIIIEDDYDSQLADETPQAALK
GLDHTGRVIYLGSMSKTLAPGLRLGYLVGPAELVAELRALRRFMLRHPPANNQRAVALFLSLGHHDSLIRRLSAAFEERR
SKLVEVIGRLMPEWEAADVPGGTSIWLQGPEGIDTGALSRAARARGVIIEPGARFFDGPERPSRHMRLGISSIAVQHIEP
GIRELAAVVSRRAIAA

Sequences:

>Translated_496_residues
MPTRNDAALWAGLIKISSDSTQTLQAQIRQAIVSAILDRQISPTMPLPSCRILADKLGVARGTVVLAFQQLVDQGFLIAR
ERRGHFVNPEVLAAPPRPPRKTRTTAKIDWKARRQVMASELPGPPKNENWMQSSYPFVYGQFDPTLFPTAEWRECNRMAL
AVLEIRNWAADMVDRDDPLLIEQIQARLLPRRGIFANPDEIIVTLGAQHALYMLATLLMGRGARVAMENPGYPDARSIFR
LSGAETLSVPVDKDGMEVDAIPADSSFVFVTPSHHCPTMVPLSRERRQALLSGAEKNDWIIIEDDYDSQLADETPQAALK
GLDHTGRVIYLGSMSKTLAPGLRLGYLVGPAELVAELRALRRFMLRHPPANNQRAVALFLSLGHHDSLIRRLSAAFEERR
SKLVEVIGRLMPEWEAADVPGGTSIWLQGPEGIDTGALSRAARARGVIIEPGARFFDGPERPSRHMRLGISSIAVQHIEP
GIRELAAVVSRRAIAA
>Mature_495_residues
PTRNDAALWAGLIKISSDSTQTLQAQIRQAIVSAILDRQISPTMPLPSCRILADKLGVARGTVVLAFQQLVDQGFLIARE
RRGHFVNPEVLAAPPRPPRKTRTTAKIDWKARRQVMASELPGPPKNENWMQSSYPFVYGQFDPTLFPTAEWRECNRMALA
VLEIRNWAADMVDRDDPLLIEQIQARLLPRRGIFANPDEIIVTLGAQHALYMLATLLMGRGARVAMENPGYPDARSIFRL
SGAETLSVPVDKDGMEVDAIPADSSFVFVTPSHHCPTMVPLSRERRQALLSGAEKNDWIIIEDDYDSQLADETPQAALKG
LDHTGRVIYLGSMSKTLAPGLRLGYLVGPAELVAELRALRRFMLRHPPANNQRAVALFLSLGHHDSLIRRLSAAFEERRS
KLVEVIGRLMPEWEAADVPGGTSIWLQGPEGIDTGALSRAARARGVIIEPGARFFDGPERPSRHMRLGISSIAVQHIEPG
IRELAAVVSRRAIAA

Specific function: Could play a regulatory role in the transcription of the moc genes for rhizopine catabolism. Could also have an aminotransferase activity [H]

COG id: COG1167

COG function: function code KE; Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Non Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH gntR-type DNA-binding domain [H]

Homologues:

Organism=Homo sapiens, GI7705897, Length=313, Percent_Identity=23.3226837060703, Blast_Score=91, Evalue=2e-18,
Organism=Homo sapiens, GI33469970, Length=313, Percent_Identity=23.3226837060703, Blast_Score=91, Evalue=2e-18,
Organism=Escherichia coli, GI1787710, Length=486, Percent_Identity=28.1893004115226, Blast_Score=133, Evalue=2e-32,
Organism=Escherichia coli, GI1790797, Length=419, Percent_Identity=27.4463007159904, Blast_Score=122, Evalue=7e-29,
Organism=Saccharomyces cerevisiae, GI6321236, Length=256, Percent_Identity=23.046875, Blast_Score=67, Evalue=8e-12,

Paralogues:

None

Copy number: 10-20 Molecules/Cell [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004839
- InterPro:   IPR000524
- InterPro:   IPR015424
- InterPro:   IPR015421
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00155 Aminotran_1_2; PF00392 GntR [H]

EC number: NA

Molecular weight: Translated: 54823; Mature: 54692

Theoretical pI: Translated: 9.37; Mature: 9.37

Prosite motif: PS50949 HTH_GNTR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPTRNDAALWAGLIKISSDSTQTLQAQIRQAIVSAILDRQISPTMPLPSCRILADKLGVA
CCCCCCHHHHEEEEEECCCCHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHCCH
RGTVVLAFQQLVDQGFLIARERRGHFVNPEVLAAPPRPPRKTRTTAKIDWKARRQVMASE
HHHHHHHHHHHHCCCCEEEECCCCCCCCCCEEECCCCCCCCCCCEEEECHHHHHHHHHHH
LPGPPKNENWMQSSYPFVYGQFDPTLFPTAEWRECNRMALAVLEIRNWAADMVDRDDPLL
CCCCCCCCCCCCCCCCEEEECCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHH
IEQIQARLLPRRGIFANPDEIIVTLGAQHALYMLATLLMGRGARVAMENPGYPDARSIFR
HHHHHHHHCCCCCCCCCCCCEEEEECCHHHHHHHHHHHHCCCCEEEECCCCCCCHHHHHE
LSGAETLSVPVDKDGMEVDAIPADSSFVFVTPSHHCPTMVPLSRERRQALLSGAEKNDWI
ECCCCEEECCCCCCCCEEEEECCCCCEEEEECCCCCCCCCCCCHHHHHHHHCCCCCCCEE
IIEDDYDSQLADETPQAALKGLDHTGRVIYLGSMSKTLAPGLRLGYLVGPAELVAELRAL
EEECCCCCHHHCCCHHHHHHCCCCCCCEEEEECCHHHHCCCCCEEEEECHHHHHHHHHHH
RRFMLRHPPANNQRAVALFLSLGHHDSLIRRLSAAFEERRSKLVEVIGRLMPEWEAADVP
HHHHHHCCCCCCCCEEEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCC
GGTSIWLQGPEGIDTGALSRAARARGVIIEPGARFFDGPERPSRHMRLGISSIAVQHIEP
CCCEEEEECCCCCCHHHHHHHHHHCCEEECCCCHHCCCCCCCCHHHHHHHHHHHHHHHCC
GIRELAAVVSRRAIAA
CHHHHHHHHHHHHHCC
>Mature Secondary Structure 
PTRNDAALWAGLIKISSDSTQTLQAQIRQAIVSAILDRQISPTMPLPSCRILADKLGVA
CCCCCHHHHEEEEEECCCCHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHCCH
RGTVVLAFQQLVDQGFLIARERRGHFVNPEVLAAPPRPPRKTRTTAKIDWKARRQVMASE
HHHHHHHHHHHHCCCCEEEECCCCCCCCCCEEECCCCCCCCCCCEEEECHHHHHHHHHHH
LPGPPKNENWMQSSYPFVYGQFDPTLFPTAEWRECNRMALAVLEIRNWAADMVDRDDPLL
CCCCCCCCCCCCCCCCEEEECCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHH
IEQIQARLLPRRGIFANPDEIIVTLGAQHALYMLATLLMGRGARVAMENPGYPDARSIFR
HHHHHHHHCCCCCCCCCCCCEEEEECCHHHHHHHHHHHHCCCCEEEECCCCCCCHHHHHE
LSGAETLSVPVDKDGMEVDAIPADSSFVFVTPSHHCPTMVPLSRERRQALLSGAEKNDWI
ECCCCEEECCCCCCCCEEEEECCCCCEEEEECCCCCCCCCCCCHHHHHHHHCCCCCCCEE
IIEDDYDSQLADETPQAALKGLDHTGRVIYLGSMSKTLAPGLRLGYLVGPAELVAELRAL
EEECCCCCHHHCCCHHHHHHCCCCCCCEEEEECCHHHHCCCCCEEEEECHHHHHHHHHHH
RRFMLRHPPANNQRAVALFLSLGHHDSLIRRLSAAFEERRSKLVEVIGRLMPEWEAADVP
HHHHHHCCCCCCCCEEEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCC
GGTSIWLQGPEGIDTGALSRAARARGVIIEPGARFFDGPERPSRHMRLGISSIAVQHIEP
CCCEEEEECCCCCCHHHHHHHHHHCCEEECCCCHHCCCCCCCCHHHHHHHHHHHHHHHCC
GIRELAAVVSRRAIAA
CHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 7845353 [H]