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The map label for this gene is mhpR [H]

Identifier: 110632413

GI number: 110632413

Start: 72123

End: 72941

Strand: Reverse

Name: mhpR [H]

Synonym: Meso_0051

Alternate gene names: 110632413

Gene position: 72941-72123 (Counterclockwise)

Preceding gene: 110632424

Following gene: 110632412

Centisome position: 1.65

GC content: 59.71

Gene sequence:

>819_bases
ATGGAGAGGTACAAACACGTCGAAGGACTATTGCGGGGATTGTCGCTGCTCAGGGCGATGAATGAGGAGGAAGGAGGCTT
CGCCACCGTGACAACGCTGGCCGATCGAACCGGCCTGCATCGCACCACGGTTAAACGCCTTCTTGAGACCCTGCACTTCG
CCGGATATGTCCAACCGGCTGAAGACCGGCGGGGATATACGCTTGCCTTGGCGGTACGGGAACTAAGCGAGGGCTTCACC
GACGAAGCCTGGATCACTCAAATAGCGGGCCCTGCCCTGGGAGAACTGGTCGAGCGCGTGGTCTGGCCTTCCGATTTCAC
GACGCCCCAAGCTGACCAGATGGTGATCCGGGAAACCACCCGTCGTTTTAGCCCCTTTTCGTTTCATCGTGCGATGGTGG
GGCAGCGCCTCCCAATGCTGCAATCCTCAGCGGGGCGCGCCTTTCTGGGATTCTGCGCCGAGAACCAACGAGAGGCCTTG
ATTCGCCACCTGCAACGAGGCGTTACCGACAGGGCAACGCGACATGCCCTCCGTCAGGCAGTGGAACACGCTGCCCGCGA
GACAGCTGCCGTCGGTTATGGATGGAACTATGGCGGGTGGAGCCGACAACAACGCTTTGGGGGAATAGCGTTACCCGTGA
TCGTCGACGGACGGGTGCTCGCCTGCCTGAGCGTGGTCTTTCTTATCAAGAGCCTGTCTCTCAGGGAGGCGGAGAACCGG
TTTCTCTCGCACCTTTCTCACGCGGTGGATCGCATCCGAAATGGTCTGATCGAGATGGGGGTAGACCGCGAATTCGTGCC
AGGTCAATCCAATCATTGA

Upstream 100 bases:

>100_bases
GGCGTAGAGGACACACCATTGGAAAATCGGCGGGTGGAGTCTAGAAGTCGGTTTTCAGACGTGCACTAAGTGCACATCAG
AAGGTGAATGGGATTGAAGC

Downstream 100 bases:

>100_bases
ATGTGCACTAAGTGCACGTTCTTGGTTTTGCTTCTGGCAGCGCGCGGTTCGAAACGTTAAATCCTTGCCAAATTGAACGG
GCAAGGGAGGAGAGCCGTGC

Product: DNA-binding transcriptional activator MhpR

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 272; Mature: 272

Protein sequence:

>272_residues
MERYKHVEGLLRGLSLLRAMNEEEGGFATVTTLADRTGLHRTTVKRLLETLHFAGYVQPAEDRRGYTLALAVRELSEGFT
DEAWITQIAGPALGELVERVVWPSDFTTPQADQMVIRETTRRFSPFSFHRAMVGQRLPMLQSSAGRAFLGFCAENQREAL
IRHLQRGVTDRATRHALRQAVEHAARETAAVGYGWNYGGWSRQQRFGGIALPVIVDGRVLACLSVVFLIKSLSLREAENR
FLSHLSHAVDRIRNGLIEMGVDREFVPGQSNH

Sequences:

>Translated_272_residues
MERYKHVEGLLRGLSLLRAMNEEEGGFATVTTLADRTGLHRTTVKRLLETLHFAGYVQPAEDRRGYTLALAVRELSEGFT
DEAWITQIAGPALGELVERVVWPSDFTTPQADQMVIRETTRRFSPFSFHRAMVGQRLPMLQSSAGRAFLGFCAENQREAL
IRHLQRGVTDRATRHALRQAVEHAARETAAVGYGWNYGGWSRQQRFGGIALPVIVDGRVLACLSVVFLIKSLSLREAENR
FLSHLSHAVDRIRNGLIEMGVDREFVPGQSNH
>Mature_272_residues
MERYKHVEGLLRGLSLLRAMNEEEGGFATVTTLADRTGLHRTTVKRLLETLHFAGYVQPAEDRRGYTLALAVRELSEGFT
DEAWITQIAGPALGELVERVVWPSDFTTPQADQMVIRETTRRFSPFSFHRAMVGQRLPMLQSSAGRAFLGFCAENQREAL
IRHLQRGVTDRATRHALRQAVEHAARETAAVGYGWNYGGWSRQQRFGGIALPVIVDGRVLACLSVVFLIKSLSLREAENR
FLSHLSHAVDRIRNGLIEMGVDREFVPGQSNH

Specific function: Activator of the mhpRABCDEF operon coding for components of the 3-hydroxyphenylpropionate degradation pathway [H]

COG id: COG1414

COG function: function code K; Transcriptional regulator

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 iclR-ED (iclR effector binding) domain [H]

Homologues:

Organism=Escherichia coli, GI145693096, Length=256, Percent_Identity=44.140625, Blast_Score=206, Evalue=2e-54,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR014757
- InterPro:   IPR005471
- InterPro:   IPR011991 [H]

Pfam domain/function: PF09339 HTH_IclR; PF01614 IclR [H]

EC number: NA

Molecular weight: Translated: 30551; Mature: 30551

Theoretical pI: Translated: 9.54; Mature: 9.54

Prosite motif: PS51077 HTH_ICLR ; PS51078 ICLR_ED

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MERYKHVEGLLRGLSLLRAMNEEEGGFATVTTLADRTGLHRTTVKRLLETLHFAGYVQPA
CCHHHHHHHHHHHHHHHHHHCCCCCCEEHHHHHHHHCCCHHHHHHHHHHHHHHHCCCCCC
EDRRGYTLALAVRELSEGFTDEAWITQIAGPALGELVERVVWPSDFTTPQADQMVIRETT
CCCCCEEHHHHHHHHHCCCCCHHHHHHHCCHHHHHHHHHHHCCCCCCCCCHHHHHHHHHH
RRFSPFSFHRAMVGQRLPMLQSSAGRAFLGFCAENQREALIRHLQRGVTDRATRHALRQA
HHCCCHHHHHHHHHHHCCHHHCCCCCHHHHHHCCCHHHHHHHHHHHCHHHHHHHHHHHHH
VEHAARETAAVGYGWNYGGWSRQQRFGGIALPVIVDGRVLACLSVVFLIKSLSLREAENR
HHHHHHHHHHHCCCCCCCCCHHHHHCCCEEEHHEECCHHHHHHHHHHHHHHHHHHHHHHH
FLSHLSHAVDRIRNGLIEMGVDREFVPGQSNH
HHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCC
>Mature Secondary Structure
MERYKHVEGLLRGLSLLRAMNEEEGGFATVTTLADRTGLHRTTVKRLLETLHFAGYVQPA
CCHHHHHHHHHHHHHHHHHHCCCCCCEEHHHHHHHHCCCHHHHHHHHHHHHHHHCCCCCC
EDRRGYTLALAVRELSEGFTDEAWITQIAGPALGELVERVVWPSDFTTPQADQMVIRETT
CCCCCEEHHHHHHHHHCCCCCHHHHHHHCCHHHHHHHHHHHCCCCCCCCCHHHHHHHHHH
RRFSPFSFHRAMVGQRLPMLQSSAGRAFLGFCAENQREALIRHLQRGVTDRATRHALRQA
HHCCCHHHHHHHHHHHCCHHHCCCCCHHHHHHCCCHHHHHHHHHHHCHHHHHHHHHHHHH
VEHAARETAAVGYGWNYGGWSRQQRFGGIALPVIVDGRVLACLSVVFLIKSLSLREAENR
HHHHHHHHHHHCCCCCCCCCHHHHHCCCEEEHHEECCHHHHHHHHHHHHHHHHHHHHHHH
FLSHLSHAVDRIRNGLIEMGVDREFVPGQSNH
HHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9278503 [H]