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The map label for this gene is ptsJ [H]

Identifier: 110632406

GI number: 110632406

Start: 52619

End: 53956

Strand: Direct

Name: ptsJ [H]

Synonym: Meso_0044

Alternate gene names: 110632406

Gene position: 52619-53956 (Clockwise)

Preceding gene: 110632396

Following gene: 110632407

Centisome position: 1.19

GC content: 60.61

Gene sequence:

>1338_bases
ATGCAGAGAATCGAAGCGAAGTGGCTGGCGGAGCTGCTGGAAGGCCGCAACGCCAAAGGCATTGCGGTCGAAACTGCGCG
GCTAATTCGCACCGGGAAGATCCCGGTGGGCGCCCGCCTCCCGGCATTGCGTGAGTTGGCCTTCTTCCTCGGTATCAGTC
CCGCTACCCTGTCAGGCGCATGGGCGGAATTGCGCAGGCAAAAGGTGATCTCAGGGCGCGGACGCAATGGTACGCTGATC
ACCGGCAAGACGATTGGCAAAGCACCGGCGCGTACTGGCCGTATGGGCCATTACACTTCCGATGCATTGGATCTTAGCTT
CGCGGTGCCCGATCCCGCTCTGCTCCCCGATCTGACCGAGGCGCTGCGAACCGCTGCGCAGAGCGCATCCCTCAACAGCT
ATCAGCGCTCTCGGATCGAACCCGCGCTCGAGGAGGCCCTGAGAGCTCGCTGGCCCTATGGCTATGAGGCACTGCTCGCA
ACCAATGGCGGCTACAATGCCGTCTATGCGACAGTGCATGCACTGGTGCAGCCAGGCGACCTTGTCGCTTGCGAGGAGCC
TACCGCGATTCGCCTGCTCGACATCATCGAGGACGCCGGCGCCAAGATCATTCCAGTGGCATGTGACGATCACGGTCCAT
TGCCCGCGAGCCTCAGCGAAGCACTCAGCCTCAAGCCGGTTTTGTTCGTCTATCAACCCCGTACGCATTCGGTGACAGGC
CGGCATGTCACGCCCGAACGGCTCGGCACACTTGGTGAATTGCTTTCATCGAGCAATGTGCTGATCCTGGAAGATGACGG
GCTTGGCGACATATCGGCCTATCCATCCCAAAGCCTCGGGTCGCGCTTTCCGGAACGCGTCATCCACGTGCAGTCTTTTT
CCAAGACTTACGGTCCCGATCTGCGTCTTGCGGTTATGTCGGCACCAGACGAGATCGTGGAGAAGGTCCAATCCTACAGA
TTGTTCAGCGCGGGCTGGACCAGCCGGCTTCTGCAAAATGTGGCCGCCTCACTGCTGTCGAGCGAACGAACCGCACGTGA
GGTTGACATGGCCCGGGAGGTCTACAAACAGCGCCGCACCGCGCTGATCGACGCGCTGGAAAAGCACGGCATCGAAGCTT
TTCGAGGGGACGGTCTCTGCATTTGGCTGGAAGTGCCGTCGGAGGCGTACGCGATGGTCACCCTGGCTGCACACAAAATC
GCCGTTCTGCCCGGTGCAAAGTGCTTTCTCGACGGGGGCGGCTTCATCCGAATTGGTACAAGCATGCTCGACCGGAAATA
TGACGAAGTCAGCCACGCAATCGCCCTTGCCTCGCGGTCTCCCGGACAGCTGCTATGA

Upstream 100 bases:

>100_bases
ACCTCTCATCCGTTTTTGGAAGTGCGAGGAGAATTAAATGTTCAATTCTTTGACACAAGTGTTATTATGTTATTGAACAT
TTAATTGTTGGGAGGGCTGC

Downstream 100 bases:

>100_bases
CGGTCTAGCGCTTCAGCTGCAGAGGGCGCACCGGCAGAGCCTCATAGCTTGAGTGATAATCAGCGCTGGCTCGCGGTGCT
TTTCGAGGAGATCGAAGACA

Product: GntR family transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 445; Mature: 445

Protein sequence:

>445_residues
MQRIEAKWLAELLEGRNAKGIAVETARLIRTGKIPVGARLPALRELAFFLGISPATLSGAWAELRRQKVISGRGRNGTLI
TGKTIGKAPARTGRMGHYTSDALDLSFAVPDPALLPDLTEALRTAAQSASLNSYQRSRIEPALEEALRARWPYGYEALLA
TNGGYNAVYATVHALVQPGDLVACEEPTAIRLLDIIEDAGAKIIPVACDDHGPLPASLSEALSLKPVLFVYQPRTHSVTG
RHVTPERLGTLGELLSSSNVLILEDDGLGDISAYPSQSLGSRFPERVIHVQSFSKTYGPDLRLAVMSAPDEIVEKVQSYR
LFSAGWTSRLLQNVAASLLSSERTAREVDMAREVYKQRRTALIDALEKHGIEAFRGDGLCIWLEVPSEAYAMVTLAAHKI
AVLPGAKCFLDGGGFIRIGTSMLDRKYDEVSHAIALASRSPGQLL

Sequences:

>Translated_445_residues
MQRIEAKWLAELLEGRNAKGIAVETARLIRTGKIPVGARLPALRELAFFLGISPATLSGAWAELRRQKVISGRGRNGTLI
TGKTIGKAPARTGRMGHYTSDALDLSFAVPDPALLPDLTEALRTAAQSASLNSYQRSRIEPALEEALRARWPYGYEALLA
TNGGYNAVYATVHALVQPGDLVACEEPTAIRLLDIIEDAGAKIIPVACDDHGPLPASLSEALSLKPVLFVYQPRTHSVTG
RHVTPERLGTLGELLSSSNVLILEDDGLGDISAYPSQSLGSRFPERVIHVQSFSKTYGPDLRLAVMSAPDEIVEKVQSYR
LFSAGWTSRLLQNVAASLLSSERTAREVDMAREVYKQRRTALIDALEKHGIEAFRGDGLCIWLEVPSEAYAMVTLAAHKI
AVLPGAKCFLDGGGFIRIGTSMLDRKYDEVSHAIALASRSPGQLL
>Mature_445_residues
MQRIEAKWLAELLEGRNAKGIAVETARLIRTGKIPVGARLPALRELAFFLGISPATLSGAWAELRRQKVISGRGRNGTLI
TGKTIGKAPARTGRMGHYTSDALDLSFAVPDPALLPDLTEALRTAAQSASLNSYQRSRIEPALEEALRARWPYGYEALLA
TNGGYNAVYATVHALVQPGDLVACEEPTAIRLLDIIEDAGAKIIPVACDDHGPLPASLSEALSLKPVLFVYQPRTHSVTG
RHVTPERLGTLGELLSSSNVLILEDDGLGDISAYPSQSLGSRFPERVIHVQSFSKTYGPDLRLAVMSAPDEIVEKVQSYR
LFSAGWTSRLLQNVAASLLSSERTAREVDMAREVYKQRRTALIDALEKHGIEAFRGDGLCIWLEVPSEAYAMVTLAAHKI
AVLPGAKCFLDGGGFIRIGTSMLDRKYDEVSHAIALASRSPGQLL

Specific function: Putative transcriptional regulator of the ptsHI/crr operon [H]

COG id: COG1167

COG function: function code KE; Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Non Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH gntR-type DNA-binding domain [H]

Homologues:

Organism=Homo sapiens, GI7705897, Length=289, Percent_Identity=27.3356401384083, Blast_Score=75, Evalue=2e-13,
Organism=Homo sapiens, GI33469970, Length=289, Percent_Identity=27.3356401384083, Blast_Score=75, Evalue=2e-13,
Organism=Escherichia coli, GI1787710, Length=448, Percent_Identity=26.5625, Blast_Score=91, Evalue=2e-19,
Organism=Escherichia coli, GI1790797, Length=459, Percent_Identity=24.400871459695, Blast_Score=73, Evalue=3e-14,

Paralogues:

None

Copy number: 10-20 Molecules/Cell [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004839
- InterPro:   IPR000524
- InterPro:   IPR015424
- InterPro:   IPR015421
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00155 Aminotran_1_2; PF00392 GntR [H]

EC number: NA

Molecular weight: Translated: 48185; Mature: 48185

Theoretical pI: Translated: 8.00; Mature: 8.00

Prosite motif: PS50949 HTH_GNTR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
1.3 %Met     (Translated Protein)
2.2 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
1.3 %Met     (Mature Protein)
2.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQRIEAKWLAELLEGRNAKGIAVETARLIRTGKIPVGARLPALRELAFFLGISPATLSGA
CCCCHHHHHHHHHCCCCCCCEEEHHHHHHHCCCCCCCCCCHHHHHHHHHHCCCCHHCCHH
WAELRRQKVISGRGRNGTLITGKTIGKAPARTGRMGHYTSDALDLSFAVPDPALLPDLTE
HHHHHHHHHHCCCCCCCCEEECCCCCCCCCCCCCCCCCCCCCCEEEEECCCCCHHHHHHH
ALRTAAQSASLNSYQRSRIEPALEEALRARWPYGYEALLATNGGYNAVYATVHALVQPGD
HHHHHHHHCCHHHHHHHHCCHHHHHHHHHCCCCCCEEEEEECCCCHHHHHHHHHHHCCCC
LVACEEPTAIRLLDIIEDAGAKIIPVACDDHGPLPASLSEALSLKPVLFVYQPRTHSVTG
EEEECCCCHHHHHHHHHHCCCEEEEEEECCCCCCCHHHHHHHCCCCEEEEECCCCCCCCC
RHVTPERLGTLGELLSSSNVLILEDDGLGDISAYPSQSLGSRFPERVIHVQSFSKTYGPD
CCCCHHHHHHHHHHHCCCCEEEEECCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCC
LRLAVMSAPDEIVEKVQSYRLFSAGWTSRLLQNVAASLLSSERTAREVDMAREVYKQRRT
EEEEEECCCHHHHHHHHHCEEHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
ALIDALEKHGIEAFRGDGLCIWLEVPSEAYAMVTLAAHKIAVLPGAKCFLDGGGFIRIGT
HHHHHHHHCCCCEECCCCEEEEEECCCCHHHHHHHHHHHEEECCCCEEEECCCCEEEECH
SMLDRKYDEVSHAIALASRSPGQLL
HHHHHHHHHHHHHHHHHCCCCCCCC
>Mature Secondary Structure
MQRIEAKWLAELLEGRNAKGIAVETARLIRTGKIPVGARLPALRELAFFLGISPATLSGA
CCCCHHHHHHHHHCCCCCCCEEEHHHHHHHCCCCCCCCCCHHHHHHHHHHCCCCHHCCHH
WAELRRQKVISGRGRNGTLITGKTIGKAPARTGRMGHYTSDALDLSFAVPDPALLPDLTE
HHHHHHHHHHCCCCCCCCEEECCCCCCCCCCCCCCCCCCCCCCEEEEECCCCCHHHHHHH
ALRTAAQSASLNSYQRSRIEPALEEALRARWPYGYEALLATNGGYNAVYATVHALVQPGD
HHHHHHHHCCHHHHHHHHCCHHHHHHHHHCCCCCCEEEEEECCCCHHHHHHHHHHHCCCC
LVACEEPTAIRLLDIIEDAGAKIIPVACDDHGPLPASLSEALSLKPVLFVYQPRTHSVTG
EEEECCCCHHHHHHHHHHCCCEEEEEEECCCCCCCHHHHHHHCCCCEEEEECCCCCCCCC
RHVTPERLGTLGELLSSSNVLILEDDGLGDISAYPSQSLGSRFPERVIHVQSFSKTYGPD
CCCCHHHHHHHHHHHCCCCEEEEECCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCC
LRLAVMSAPDEIVEKVQSYRLFSAGWTSRLLQNVAASLLSSERTAREVDMAREVYKQRRT
EEEEEECCCHHHHHHHHHCEEHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
ALIDALEKHGIEAFRGDGLCIWLEVPSEAYAMVTLAAHKIAVLPGAKCFLDGGGFIRIGT
HHHHHHHHCCCCEECCCCEEEEEECCCCHHHHHHHHHHHEEECCCCEEEECCCCEEEECH
SMLDRKYDEVSHAIALASRSPGQLL
HHHHHHHHHHHHHHHHHCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 7612925; 11677609 [H]