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The map label for this gene is ybeM [H]

Identifier: 110632404

GI number: 110632404

Start: 50737

End: 51528

Strand: Reverse

Name: ybeM [H]

Synonym: Meso_0042

Alternate gene names: 110632404

Gene position: 51528-50737 (Counterclockwise)

Preceding gene: 110632405

Following gene: 110632403

Centisome position: 1.17

GC content: 61.11

Gene sequence:

>792_bases
ATGAAGGTTGCGCTTGGCCAATTCGCGGCAGCGAACGAATGGCGTAGGAACGCGGAGACAGCCACCGCGATCATGGCGAA
AGCCAAGAATGCAAAATGCGACCTTCTGGTTCTCCCTGAGGGTATCCTGGCGCGCGATATCACCGATCCCGACATCGTCC
TCAAGGCCGCACAGCCCTTGGACGGTCCGTTCATGACGGAGATGCTGCGGGCCAGCGAAGGCTCTCAGATGACGACCATG
TTCTGCATTCATGTGCCGATCGAGGGCGAGACGCGCGTGCATAATGTGCTGGTCGCATTGCGCGATGGCAAGATCATCGC
CGCGTACAGAAAGCTGCATCTCTACGACGCCTTCGCCGCCCTGGAATCAACGCATGTCATGCCGGGCACGGCCATTCCGG
ATCTCGTGGAGGTGGCCGGCTTCAAGGTGGGGCTCATGACCTGCTACGATGTCCGCTTTCCCGAATTGGCGCGTCATCAC
GCCGTGGCTGGGGCCGACGTGCTTGCACTACCGGCGGCATGGGTCAGGGGCCCCGGCAAGGAACACCACTGGGAGACCCT
CGTTACAGCGCGGGCGTTGGAGAACACCTGTTATGTAATTGCCGTTGGCGAATGTGGCCCGCGCAACATCGGTGCGAGCA
TGATTGTCGATCCGCTCGGCGTGGTGACGCATCGGGCCGGCGAAGACCCGACGCTGATATTTGCCGATATCGAGCGCGAG
CGCCTTACCCACGCAAGAAGCGCCTTGCCAGTGCTTGCCAACCGCCAGTTCGCACAACCGCAACTGGCTTAA

Upstream 100 bases:

>100_bases
CTTACGACCAGAGGCTGATCCCGGCGCCCATTGCACCCGAGAACATCTTTGCATCGCCGGCAGAGCAGGCTGAAGCCAAA
AACTACGAGGAAGACAAGGT

Downstream 100 bases:

>100_bases
TCGCTTCAGAGAGAGGAAAGGGAGGAGAATCATGTCAAATACCATGCTGAAATACGGCGTTGCCATACTCGTCGCTGGTT
TCATGGCTGGTGCCGCACAG

Product: Nitrilase/cyanide hydratase and apolipoprotein N-acyltransferase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 263; Mature: 263

Protein sequence:

>263_residues
MKVALGQFAAANEWRRNAETATAIMAKAKNAKCDLLVLPEGILARDITDPDIVLKAAQPLDGPFMTEMLRASEGSQMTTM
FCIHVPIEGETRVHNVLVALRDGKIIAAYRKLHLYDAFAALESTHVMPGTAIPDLVEVAGFKVGLMTCYDVRFPELARHH
AVAGADVLALPAAWVRGPGKEHHWETLVTARALENTCYVIAVGECGPRNIGASMIVDPLGVVTHRAGEDPTLIFADIERE
RLTHARSALPVLANRQFAQPQLA

Sequences:

>Translated_263_residues
MKVALGQFAAANEWRRNAETATAIMAKAKNAKCDLLVLPEGILARDITDPDIVLKAAQPLDGPFMTEMLRASEGSQMTTM
FCIHVPIEGETRVHNVLVALRDGKIIAAYRKLHLYDAFAALESTHVMPGTAIPDLVEVAGFKVGLMTCYDVRFPELARHH
AVAGADVLALPAAWVRGPGKEHHWETLVTARALENTCYVIAVGECGPRNIGASMIVDPLGVVTHRAGEDPTLIFADIERE
RLTHARSALPVLANRQFAQPQLA
>Mature_263_residues
MKVALGQFAAANEWRRNAETATAIMAKAKNAKCDLLVLPEGILARDITDPDIVLKAAQPLDGPFMTEMLRASEGSQMTTM
FCIHVPIEGETRVHNVLVALRDGKIIAAYRKLHLYDAFAALESTHVMPGTAIPDLVEVAGFKVGLMTCYDVRFPELARHH
AVAGADVLALPAAWVRGPGKEHHWETLVTARALENTCYVIAVGECGPRNIGASMIVDPLGVVTHRAGEDPTLIFADIERE
RLTHARSALPVLANRQFAQPQLA

Specific function: Unknown

COG id: COG0388

COG function: function code R; Predicted amidohydrolase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 CN hydrolase domain [H]

Homologues:

Organism=Homo sapiens, GI5031947, Length=273, Percent_Identity=34.4322344322344, Blast_Score=132, Evalue=2e-31,
Organism=Homo sapiens, GI297632350, Length=273, Percent_Identity=34.4322344322344, Blast_Score=132, Evalue=2e-31,
Organism=Homo sapiens, GI297632348, Length=273, Percent_Identity=34.4322344322344, Blast_Score=132, Evalue=2e-31,
Organism=Homo sapiens, GI9910460, Length=202, Percent_Identity=29.7029702970297, Blast_Score=93, Evalue=3e-19,
Organism=Homo sapiens, GI297632346, Length=197, Percent_Identity=31.9796954314721, Blast_Score=80, Evalue=2e-15,
Organism=Caenorhabditis elegans, GI17556280, Length=267, Percent_Identity=30.3370786516854, Blast_Score=116, Evalue=9e-27,
Organism=Saccharomyces cerevisiae, GI6322335, Length=300, Percent_Identity=29.6666666666667, Blast_Score=131, Evalue=1e-31,
Organism=Saccharomyces cerevisiae, GI6323383, Length=182, Percent_Identity=34.6153846153846, Blast_Score=96, Evalue=7e-21,
Organism=Drosophila melanogaster, GI17933642, Length=268, Percent_Identity=28.3582089552239, Blast_Score=96, Evalue=2e-20,
Organism=Drosophila melanogaster, GI21355835, Length=272, Percent_Identity=27.2058823529412, Blast_Score=91, Evalue=7e-19,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003010
- InterPro:   IPR001110 [H]

Pfam domain/function: PF00795 CN_hydrolase [H]

EC number: 3.5.-.- [C]

Molecular weight: Translated: 28572; Mature: 28572

Theoretical pI: Translated: 6.67; Mature: 6.67

Prosite motif: PS50263 CN_HYDROLASE ; PS01227 UPF0012

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.9 %Cys     (Translated Protein)
3.4 %Met     (Translated Protein)
5.3 %Cys+Met (Translated Protein)
1.9 %Cys     (Mature Protein)
3.4 %Met     (Mature Protein)
5.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKVALGQFAAANEWRRNAETATAIMAKAKNAKCDLLVLPEGILARDITDPDIVLKAAQPL
CCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCEEEEECCCCHHCCCCCCHHHEEEECCCC
DGPFMTEMLRASEGSQMTTMFCIHVPIEGETRVHNVLVALRDGKIIAAYRKLHLYDAFAA
CCHHHHHHHHHCCCCCEEEEEEEEECCCCCCCEEEEEEEEECCCEEEEHHHHHHHHHHHH
LESTHVMPGTAIPDLVEVAGFKVGLMTCYDVRFPELARHHAVAGADVLALPAAWVRGPGK
HHCCCCCCCCCCHHHHHHHCCEEEEEEEECCCCHHHHHHHHHCCCCHHHHCHHHHCCCCC
EHHWETLVTARALENTCYVIAVGECGPRNIGASMIVDPLGVVTHRAGEDPTLIFADIERE
CCHHHHHHHHHHHCCCEEEEEECCCCCCCCCHHHHHCCHHHHHHCCCCCCEEEEEECCHH
RLTHARSALPVLANRQFAQPQLA
HHHHHHHCCHHHHCCCCCCCCCC
>Mature Secondary Structure
MKVALGQFAAANEWRRNAETATAIMAKAKNAKCDLLVLPEGILARDITDPDIVLKAAQPL
CCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCEEEEECCCCHHCCCCCCHHHEEEECCCC
DGPFMTEMLRASEGSQMTTMFCIHVPIEGETRVHNVLVALRDGKIIAAYRKLHLYDAFAA
CCHHHHHHHHHCCCCCEEEEEEEEECCCCCCCEEEEEEEEECCCEEEEHHHHHHHHHHHH
LESTHVMPGTAIPDLVEVAGFKVGLMTCYDVRFPELARHHAVAGADVLALPAAWVRGPGK
HHCCCCCCCCCCHHHHHHHCCEEEEEEEECCCCHHHHHHHHHCCCCHHHHCHHHHCCCCC
EHHWETLVTARALENTCYVIAVGECGPRNIGASMIVDPLGVVTHRAGEDPTLIFADIERE
CCHHHHHHHHHHHCCCEEEEEECCCCCCCCCHHHHHCCHHHHHHCCCCCCEEEEEECCHH
RLTHARSALPVLANRQFAQPQLA
HHHHHHHCCHHHHCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]